Novel effects of strains in graphene and other two dimensional materials

The analysis of the electronic properties of strained or lattice deformed graphene combines ideas from classical condensed matter physics, soft matter, and geometrical aspects of quantum field theory (QFT) in curved spaces. Recent theoretical and experimental work shows the influence of strains in many properties of graphene not considered before, such as electronic transport, spin-orbit coupling, the formation of Moir\'e patterns, optics, ... There is also significant evidence of anharmonic effects, which can modify the structural properties of graphene. These phenomena are not restricted to graphene, and they are being intensively studied in other two dimensional materials, such as the metallic dichalcogenides. We review here recent developments related to the role of strains in the structural and electronic properties of graphene and other two dimensional compounds.Comment: 75 pages, 15 figures, review articl

Pleistocene climate changes, and not agricultural spread, accounts for range expansion and admixture in the dominant grassland species <i>Lolium perenne</i> L.

International audienceAim: Grasslands have been pivotal in the development of herbivore breeding since the Neolithic and still represent the most widespread agricultural land use across Europe. However, it remains unclear whether the current large‐scale genetic variation of plant species found in natural grasslands of Europe is the result of human activities or natural processes. Location: Europe. Taxon: Lolium perenne L. (perennial ryegrass). Methods: We reconstructed the phylogeographic history of L. perenne, a dominant grassland species, using 481 natural populations, including 11 populations of closely related taxa. We combined Genotyping‐by‐Sequencing (GBS) and pool‐Sequencing (pool‐Seq) to obtain high‐quality allele frequency calls of ~500 k SNP loci. We performed genetic structure analyses and demographic reconstructions based on the site frequency spectrum (SFS). We additionally used the same genotyping protocol to assess the genomic diversity of a set of 32 cultivars representative of the L. perenne cultivars widely used for forage purposes. Results: Expansion across Europe took place during the Würm glaciation (12–110 kya), a cooling period that decreased the dominance of trees in favour of grasses. Splits and admixtures in L. perenne fit historical climate changes in the Mediterranean basin. The development of agriculture in Europe (7–3.5 kya), that caused an increase in the abundance of grasslands, did not have an effect on the demographic patterns of L. perenne. We found that most modern cultivars are closely related to natural diversity from north-western Europe. Thus, modern cultivars do not represent the wide genetic variation found in natural populations. Main conclusions: Demographic events in L. perenne can be explained by the changing climatic conditions during the Pleistocene. Natural populations maintain a wide genomic variability at continental scale that has been minimally exploited by recent breeding activities. This variability constitutes valuable standing genetic variation for future adaptation of grasslands to climate change, safeguarding the agricultural services they provide

Quality criteria of physiotherapy grade (diploma): report provided by the Spanish Association and Physiotherapists

[Resumen] El informe sobre criterios de calidad específicos de recursos materiales y profesorado para el título de grado de Fisioterapia ha sido elaborado por la Asociación Española de Fisioterapeutas que convocó, con tal finalidad, a una comisión de expertos en Educación en Fisioterapia. El documento, realizado a propuesta de la Dirección General de Universidades en diciembre de 2004, tiene por objetivo el establecer los criterios mínimos de recursos materiales y humanos derivados de la especificidad de la titulación de Fisioterapia, que permita cubrir las nuevas demandas de la sociedad. En relación a los recursos materiales, se ha procurado darle un suficiente grado de especificación cuantitativa y cualitativa a los instrumentos que constituyen los recursos materiales específicos. La intención es, así mismo, facilitar su valoración en el momento de acreditar la titulación. Se abordan, por una parte, los recursos específicos de la titulación para la docencia teórico-práctica en el centro, dentro de los laboratorios destinados a tal efecto. Por otra parte, se definen las características o perfil de los centros sociosanitarios donde debe impartirse la formación clínica del alumno. En relación a los recursos humanos, se hace especial hincapié en el perfil y la experiencia del profesorado para la docencia, así como en el ratio profesor-alumno en la formación práctica y en la formación clínica.[Abstract] The report about specific quality criteria of resources material (items) and teaching profession to obtain the Physiotherapy Grade, has been elaborated by the Spanish Association of Physiotherapists, which aimed to convoke a Physiotherapy Education experts commission. The document was carried out on Universities General Chairmene’s proposal, aiming to establish the minimum criteria of human and Material (Items) resources, derived from the specific Physical Therapy Grade (Diploma), Which may cover the latest Society requirements. According to the Material resources, there has been a serious attempt to give the instruments, which constitute the specific material resources, an appropriate degree, quantitative and qualitative specification. The main intention by itself, consists of providing its assessment when the time to accredit the title comes. On the one hand the specific resources of the Physiotherapy Grade for the Theoric-practical Teaching in the Centre are taken up even in the laboratories aimed to get such goal. On the other hand we define the characteristics or the profile of the social. Health centres, where Pupils’ Clinical Education, must be carried out. Relating to the Human Resources, we do underline the Teaching Profession experience and profile, as well as the rate Teacher-Pupil, both in the practical Training and the Clinical Education, too

Canonical correlations reveal adaptive loci and phenotypic responses to climate in perennial ryegrass

Germplasm from perennial ryegrass (Lolium perenne L.) natural populations is useful for breeding because of its adaptation to a wide range of climates. Climate‐adaptive genes can be detected from associations between genotype, phenotype and climate but an integrated framework for the analysis of these three sources of information is lacking. We used two approaches to identify adaptive loci in perennial ryegrass and their effect on phenotypic traits. First, we combined Genome‐Environment Association (GEA) and GWAS analyses. Then, we implemented a new test based on a Canonical Correlation Analysis (CANCOR) to detect adaptive loci. Furthermore, we improved the previous perennial ryegrass gene set by de novo gene prediction and functional annotation of 39,967 genes. GEA‐GWAS revealed eight outlier loci associated with both environmental variables and phenotypic traits. CANCOR retrieved 633 outlier loci associated with two climatic gradients, characterized by cold‐dry winter versus mild‐wet winter and long rainy season versus long summer, and pointed out traits putatively conferring adaptation at the extremes of these gradients. Our CANCOR test also revealed the presence of both polygenic and oligogenic climatic adaptations. Our gene annotation revealed that 374 of the CANCOR outlier loci were positioned within or close to a gene. Co‐association networks of outlier loci revealed a potential utility of CANCOR for investigating the interaction of genes involved in polygenic adaptations. The CANCOR test provides an integrated framework to analyse adaptive genomic diversity and phenotypic responses to environmental selection pressures that could be used to facilitate the adaptation of plant species to climate change

Design and creation of informative pills from professional seminars and conferences in Business Administration Degree and Master in Foreign Trade

Este proyecto propone el uso de las nuevas tecnologías y, en concreto, del concepto de “cápsula informativa” para incentivar la motivación del alumnado en su aprendizaje y dar un mejor uso de algunas de las actividades propuestas en el aula, de manera que se incremente su perdurabilidad y que el esfuerzo que supone su organización no caiga en saco roto. El contenido concreto de las cápsulas se ha pretendido que sea un compendio de mini-entrevistas a los profesionales que visitan las aulas de la titulación en distintas asignaturas y que proceden del mundo de la empresa (emprendedores, directores de departamentos de comercio exterior, directivos de multinacionales, técnicos de la Cámara de Comercio, etc.).This project proposes the use of new technologies and, in particular, the concept of "information pill" to encourage student motivation in their learning and give better use of some of the activities proposed in the classroom in order to increase their durability and that the effort they suppose do not fall on deaf ears. The specific content of the pills has been intended to be a compendium of mini-interviews to professionals who visit the classrooms in different subjects and who come from business world (entrepreneurs, directors of foreign trade departments, managers of multinationals, technicians of the Chamber of Commerce, etc.)

Thrombopoietin Receptor Agonists for Severe Thrombocytopenia after Allogeneic Stem Cell Transplantation : Experience of the Spanish Group of Hematopoietic Stem Cell Transplant

Persistent thrombocytopenia is a common complication after allogeneic hematopoietic stem cell transplantation (allo-SCT). Romiplostim and eltrombopag are the currently available thrombopoietin receptor agonists (TPO-RAs), and some studies with very small numbers of cases have reported their potential efficacy in the allo-SCT setting. The present retrospective study evaluated the safety and efficacy of TPO-RAs in 86 patients with persistent thrombocytopenia after allo-HSCT. Sixteen patients (19%) had isolated thrombocytopenia (PT), and 71 (82%) had secondary failure of platelet recovery (SFPR). TPO-RA therapy was started at a median of 127 days (range, 27 to 1177 days) after allo-SCT. The median initial and maximum administered doses were 50 mg/day (range, 25 to 150 mg/day) and 75 mg/day (range, 25 to 150 mg/day), respectively, for eltrombopag and 1 µg/kg (range, 1 to 7 µg/kg) and 5 µg/kg (range, 1 to 10 µg/kg), respectively, for romiplostin. The median platelet count before initiation of TPO-RA therapy was 14,000/µL (range, 1000 to 57,000/µL). Platelet recovery to ≥50,000/µL without transfusion support was achieved in 72% of patients at a median time of 66 days (range, 2 to 247 days). Eighty-one percent of the patients had a decreased number of megakaryocytes before treatment, showing a slower response to therapy (P =.011). The median duration of treatment was 62 days (range, 7 to 700 days). Grade 3-4 adverse events (hepatic and asthenia) were observed in only 2% of the patients. At last follow-up, 81% of patients had discontinued TPO-RAs and maintained response, and 71% were alive. To our knowledge, this is the largest series analyzing the use of TPO-RAs after allo-SCT reported to date. Our results support the efficacy and safety in this new setting. Further prospective trials are needed to increase the level of evidence and to identify predictors of response

Teaching material for the visibilization of models in the female entrepreneurship. Raising awareness in self-employment

En un momento de grandes cambios, la docencia universitaria no se encuentra ajena a los retos y necesidades planteados por la sociedad en la que desenvuelve su actividad. Juega una especial importancia el papel de la mujer como agente dinamizador de la actividad económica. En este sentido la universidad debe de tratar de fomentar el espíritu emprendedor entre el alumnado. Según esto, este proyecto se orienta hacia la elaboración de material docente para la mejora de la visibilización del rol empresarial de la mujer mediante la elaboración de casos de emprendimiento femenino. El material docente se ha materializado en un libro coeditado por el Consejo Social de la universidad de Córdoba, la Fundación Caja Rural del Sur y la editorial Tirant lo Blanc (indexada en el primer cuartil del índice SPI). Dicho material proporciona una variada selección de casos reales que el alumno puede consultar convirtiéndose así en un complemento didáctico esencial en la Asignatura de Creación de Empresas. Además, a medio plazo, este libro, mediante su continua utilización en próximos cursos, podría permitir hacer un seguimiento y medición de las tasas de respuesta en intención emprendedora entre los alumnos.In a time of great changes, university teaching is not alien to the challenges and needs that the society in which it develops its activity poses. The role of women as a dynamic agent of economic activity plays a special role. In this sense, the university should try to foster an entrepreneurial spirit among the students. According to this, this project is oriented towards the development of teaching material for the visibility of female entrepreneurship cases. The teaching material has materialized in a book in editing process coedited by the social council of the University of Córdoba and the publishing house Tirant lo Blanc (indexed in the first quartile of the SPI index). This material provides a selection of real and varied cases that the student can consult, thus becoming an essential didactic complement in the Business Creation Course. In the medium term, this book, through its continuous use in future courses, could allow to track and measure response rates entrepreneurial intention among students

Ingeniería Forestal y ambiental en medios insulares

Las Islas Canarias a pesar de su reducida extensión y del relativo poco peso específico a nivel mundial, no es ajena a los problemas globales detectados en la conservación de bosques y en la importancia que éstos tienen para obtener beneficios económicos, socioculturales y ambientales. La gestión forestal sostenible es en este sentido esencial para asegurar y compatibilizar los diversos beneficios del bosque. El papel específico de los bosques y su gestión son sin embargo temas aún por conocer en nuestras islas, por lo que el Año Internacional de los Bosques ha representado una oportunidad única para dar a conocer el mundo forestal y acercarlo a nuestra sociedad. El presente libro consta de 25 capítulos donde se ha contemplado la mayoría de los aspectos a tener en cuenta en la planificación y gestión del medio forestal y natural. Desde la historia forestal del archipiélago, hasta el uso y técnicas de manejo de los recursos naturales, incluyendo el agua, la energía en forma de biomasa y la selvicultura