193 research outputs found

    Prediction of Compressive Strength and Evaluation of Different Theoretical Standards and Proposed Models of Brick Columns Confined with FRP, FRCM, or SRG System

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    The Strength Capacity of Confined Masonry Column is One of the Topics that Need to Be Studied. in This Study, the Efficiency of using Different Types of Advanced Composite (Non-Corrosive Materials) Such as Fiber Reinforced Polymer (FRP), Fiber Reinforced Cementitious Matrix (FRCM), or Steel Reinforced Grout (SRG) in Confining Masonry Columns is Investigated. a Wide Range of Experimental Database of Masonry Column Specimens Has Been Collected from the Results that Available in Scientific Literatures. Different Theoretical Standards and Proposed Models that Used to Predict the Capacity of Masonry Columns Confined with FRP and FRCM Are Evaluated based on Collected Experimental Database. Since There is No Standard Code or Specific Proposed Model for SRG System, the Confined Capacity of This System is Predicted and Evaluated using the FRCM Proposed Models. the Justification of using These Models is that Both FRCM and SRG Systems Have the Same Concept of using Inorganic Material as a Paste Material. an Index Named Equivalent Fiber Reinforcement Index (EFRI) is Proposed to Capture the Key Factors that Control the Behavior of the Confined Masonry Columns with Different Advanced Composite. This Index is Used as Reference Parameter for the Purpose of the Comparison between Different Strengthening Systems. as a Result, All Types of Advanced Composite Presented a Significant Increase in Ultimate Capacity. Also, the Behavior of the Masonry Columns Was Significantly Dependent on the Type of Fabric Used. Different Modes of Failure Were Reported, Including Crushing of Masonry Block, as Well as a Deboning of FRP from the Masonry Substrate and Deboning or Slippage of Fabric within Inorganic Paste Matrix. Compared with Other Models and Standards, the American Concrete Institute Committee 440 (ACI 440) and American Concrete Institute Committee 549 (ACI 549) Shows Very Good Predictions for the Confined Capacity of Masonry Columns Strengthened by FRP and FRCM or SRG Respectively

    LES, DNS, and RANS for the Analysis of High-Speed Turbulent Reacting Flows

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    A filtered density function (FDF) method suitable for chemically reactive flows is developed in the context of large eddy simulation. The advantage of the FDF methodology is its inherent ability to resolve subgrid scales (SGS) scalar correlations that otherwise have to be modeled. Because of the lack of robust models to accurately predict these correlations in turbulent reactive flows, simulations involving turbulent combustion are often met with a degree of skepticism. The FDF methodology avoids the closure problem associated with these terms and treats the reaction in an exact manner. The scalar FDF approach is particularly attractive since it can be coupled with existing hydrodynamic computational fluid dynamics (CFD) codes

    Serosurvey of human antibodies recognizing Aedes aegypti D7 salivary proteins in Colombia

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    Citation: Londono-Renteria, B. L., Shakeri, H., Rozo-Lopez, P., Conway, M. J., Duggan, N., Jaberi-Douraki, M., & Colpitts, T. M. (2018). Serosurvey of Human Antibodies Recognizing Aedes aegypti D7 Salivary Proteins in Colombia. Frontiers in Public Health, 6. https://doi.org/10.3389/fpubh.2018.00111Background: Dengue is one of the most geographically significant mosquito-borne viral diseases transmitted by Aedes mosquitoes. During blood feeding, the mosquito deposits salivary proteins that induce antibody responses. These can be related to the intensity of exposure to bites. Some mosquito salivary proteins, such as D7 proteins, are known as potent allergens. The antibody response to D7 proteins can be used as a marker to evaluate the risk of exposure and disease transmission, and provide critical information for understanding the dynamics of vector-host interactions. Methods: The study was conducted at the Los Patios Hospital, Cucuta, Norte de Santander, Colombia. A total of 63 participants were enrolled in the study. Participants were categorized into three disease status groups, age groups, and socioeconomic strata. The level of IgG antibodies against D7 Aedes proteins was determined by ELISA. We used a statistical approach to determine if there is an association between antibody levels and factors such as age, living conditions, and dengue virus infection. Results: We found that IgG antibodies against D7 proteins were higher in non-DENV infected individuals in comparison to DENV-infected participants. Also, age factor showed a significant positive correlation with IgG antibodies against D7 proteins, and the living conditions (socioeconomic stratification), in people ages 20 years or older, are a statistically significant factor in the variability of IgG antibodies against D7 proteins. Conclusions: This pilot study represents the first approximation to elucidate any correlation between the antibody response against mosquito D7 salivary proteins and its correlation with age, living conditions and dengue virus infection in a dengue endemic area

    Corynebacterium species inhibit Streptococcus pneumoniae colonization and infection of the mouse airway

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    The stability and composition of the airway microbiome is an important determinant of respiratory health. Some airway bacteria are considered to be beneficial due to their potential to impede the acquisition and persistence of opportunistic bacterial pathogens such a

    Evaluation of Precision Livestock Technology and Human Scoring of Nursery Pigs in a Controlled Immune Challenge Experiment

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    The objectives were to determine the sensitivity, specificity, and cutoff values of a visual-based precision livestock technology (NUtrack), and determine the sensitivity and specificity of sickness score data collected with the live observation by trained human observers. At weaning, pigs (n = 192; gilts and barrows) were randomly assigned to one of twelve pens (16/pen) and treatments were randomly assigned to pens. Sham-pen pigs all received subcutaneous saline (3 mL). For LPS-pen pigs, all pigs received subcutaneous lipopolysaccharide (LPS; 300 µg/kg BW; E. coli O111:B4; in 3 mL of saline). For the last treatment, eight pigs were randomly assigned to receive LPS, and the other eight were sham (same methods as above; half-and-half pens). Human data from the day of the challenge presented high true positive and low false positive rates (88.5% sensitivity; 85.4% specificity; 0.871 Area Under Curve, AUC), however, these values declined when half-and-half pigs were scored (75% sensitivity; 65.5% specificity; 0.703 AUC). Precision technology measures had excellent AUC, sensitivity, and specificity for the first 72 h after treatment and AUC values were \u3e0.970, regardless of pen treatment. These results indicate that precision technology has a greater potential for identifying pigs during a natural infectious disease event than trained professionals using timepoint sampling

    Identifying a Milk-Replacer and Weaning Strategy for Holstein Calves Using Automated Behavioral Measures of Lying and Environmental Enrichment Device Use

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    In dairy production, “weaning readiness” is often based on solid feed intake. The goal of this study was to determine weaning readiness using feed-intake, lying-behaviors, and the use of an environmental enrichment device (EED) in calves that underwent 1 of 4 milk-replacer and weaning protocols. Twenty-eight male Holstein calves (95 ± 2.6 lb BW at 1 d of age) were housed in individual pens and initially fed one type of milk replacer (25% crude protein (CP), 17% fat, 1.45 lb of dry matter (DM)) via nipplebuckets twice a day (AM and PM), and one type of textured calf starter (ad libitum; 20% CP and 37% starch). At age 3 days, calves were randomly assigned to one of the four nutrition-weaning strategies:1. MOD-STEP - 1.46 lb per day of milk replacer; 2-step weaned, initiated at age 6 weeks, completed 3 days later; 2. HI-STEP - 2.4 lb per day of milk replacer; 2-step weaned, initiated at age 5 weeks and completed 1 week later; 3. HI-LATE - 2.4 lb per day of milk replacer; 2-step weaned, initiated at age 7 weeks and completed 1 week later; and 4. HI-GRAD - 2.4 lb per day of milk replacer; 5-step weaned, initiated at age 6 week and completed 2 weeks later. Each calf’s pen had an EED, which included a dummy-nipple attached to a bottle and holder. A sensor and automated logger tracked each event (1 Hz) that the calf manipulated the EED (25 Hz sensitivity). Each calf was fitted with an accelerometer on the back leg to automatically measure lying behaviors. The device collected the y-axis (lie vs. stand) and z-axis (right or left percent during lying) of the calf every minute. For this experiment, 3-day sample periods were analyzed before and after weaning was initiated. In addition, the 3 days following weaning-completion were sampled. Feed intake among MOD-STEP calves increased by 1.0 ± 0.19 lb after the first bottle was removed (P ≤ 0.05), and then by 1.5 ± 0.19 SE lb after completion of weaning (P ≤ 0.05). The use of EED did not change among MOD-STEP calves (P \u3e 0.05), but after weaning, they increased their lying time, especially on their left side (P ≤ 0.05). These changes in lying-behaviors may indicate increased comfort and maturity of the rumen. On the contrary, calves in the HI-STEP treatment ate the least amount of feed overall (P \u3c 0.05), and they used the EED the most (P \u3e 0.05). Calves in the HI-STEP treatment showed reduced lying bouts after weaning (P ≤ 0.05), but no other lying-measures changed (P \u3e 0.05). The HI-LATE calves had similar feed intake and EED use compared to MOD-STEP calves. These findings suggest that weaning age needs to be more than 8 weeks for calves fed 2.4 lb of milk replacer per day. Gradual weaning may also improve feed intake and reduce EED use. When calves were gradually weaned starting at age 6 weeks and completed at age 8 weeks, they had the same amount of solid feed intake as HI-LATE calves. More research is needed to determine if increased feed intake and reduced EED use are also indicators that cross-sucking is less likely to occur when calves are grouped after weaning

    Synthesis of MnO-NiO-SO4 2/ZrO2 solid acid catalyst for methyl ester production from palm fatty acid distillate

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    Biodiesel is a found promising alternative biofuel to popular fossil fuel because of to its renewable and biodegradable nature and thus is considered as environmentally benign. This paper reports on the synthesis of a novel heterogeneous manganese-nickel doped on sulfated zirconia catalyst (MnO-NiO-SO4−2/ZrO2) by using simple wet impregnation method for biodiesel production from palm fatty acid distillate (PFAD). The synthesized catalyst was characterized through ammonia temperature programmed desorption (TPD-NH3), X-ray diffraction (XRD), Fourier transform infrared (FTIR), pyridine adsorption via FTIR, scanning electron microscopy (SEM) and thermal gravimetric analysis (TGA) techniques. The synthesized catalyst was tested for PFAD through esterification reaction where more than 97% of biodiesel yield was observed under the optimized reaction conditions of 15:1 methanol to PFAD ratio, 70 °C reaction temperature, 3 wt% catalyst loading and 3 h reaction time. The reusability of the catalyst was tested and found that it could be reused for at least five times without significant reduction in activity. Hence, the catalyst was found suitable for biodiesel production from low grade feedstock

    The effect of malnutrition on patients undergoing elective joint arthroplasty.

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    Malnutrition has been linked to serious complications in patients undergoing elective total joint arthroplasty (TJA). This study prospectively evaluated 2,161 patients undergoing elective TJA for malnutrition as defined by either an abnormal serum albumin or transferrin. The overall incidence of malnutrition was 8.5% (184 of 2,161) and the rate of overall complications in the malnourished group was 12% as compared to 2.9% in patients with normal parameters (P55years-old undergoing TJA and is associated with a significant increase in post-operative complications

    Adult urinary bladder tumors with rabdomyosarcomatous differentiation: Clinical, pathological and immunohistochemical studies

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    Adult rhabdomyosarcoma (RMS) in the urinary bladder is rare, and is the subject of case reports and small series. It consists of sheets of small round blue cells with high nuclear cytoplasmic ratio, brisk mitosis and apoptosis. In this study, we reported one case of pure rhabdomyosarcoma and two cases of urothelial carcinomas with extensive rhabdomyosarcomatous differentiation. In addition, their immunohistochemical profile was compared to that of small cell carcinoma of the bladder. Our study showed that sufficient sampling was critical for the diagnosis of urothelial carcinoma with extensive rhabdomyosarcomatous differentiation. As adult RMS in the bladder and urothelial carcinoma with rhabdomyosarcomatous differentiation shared morphological features with small cell carcinoma of the bladder, appropriate immunohistochemical stains were necessary in the differential diagnosis. We showed both rhabdomyosarcoma and rhabdomyosarcomatous areas of the urothelial carcinoma were positive for myogenin, negative for cytokeratin and chromogranin stains. In contrast, small cell carcinoma was positive for cytokeratin, and 7 out of 9 cases were also positive for chromogranin. Both rhabdomyosarcoma and small cell carcinoma could be positive for synaptophysin, a potential pitfall to avoid. In addition, all of the tumors with rhabdomyosarcomatous differentiation were negative for FKHR rearrangement
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