Physical profile comparison between 3x3 and 5x5 basketball training

El objetivo del estudio fue comparar las demandas físicas a partir de variables de distancia, velocidad y aceleración en baloncesto entre dos juegos reducidos, 3x3 y 5x5, mediante tecnología GPS. Diez mujeres (15 ±1,0 años) participaron en el estudio, durante dos sesiones de entrenamiento. Se aplicaron las reglas de las competiciones 3 contra 3 en una sola canasta y a media cancha. Las jugadoras participaron en dos juegos (5x5 y 3x3) durante 5 minutos cada uno. Las jugadoras fueron organizadas en función de su puesto específico. Las variables utilizadas para analizar los datos registrados se agruparon en: indicadores físicos globales (distancia total o DT, velocidad media o DT/min, Player Load o PL y Velocidad máxima o Vmax), distancia recorrida en diferentes rangos de velocidad y distancia recorrida en diferentes rangos de aceleración. El análisis de datos mostró valores más altos en el 3x3, existiendo diferencias significativas en las variables DT, DT/min y PL, distancia recorrida en el rango de >1,0 m/s-1 y en la mayoría de los rangos de aceleración. La interpretación de los resultados sugiere que el espacio afectó en la demanda física de las jugadorasThe aim of the study was to compare the physical requirements taking into account the variables of distance, velocity and acceleration in basketball between two small-sided games, 3x3 and 5x5, using GPS technology. Ten women (15 ±1.0 years) participated in the study, during two training sessions. The rules of 3v3 competitions were applied in a single basket half-court. The players participated in two games (5x5 and 3x3) during 5 minutes each. The players were organized according to their specific position. The variables used to analyze the recorded data were grouped into: global physical indicators (total distance or DT, average speed or DTmin, Player Load or PL and maximum speed or Vmax), traversed distance in different ranges of speed and traversed distance in different ranges of acceleration. The data-analysis showed higher values in the 3x3, being significant differences in the variables DT, DT/min and PL, traversed distance in the range of 1.0 m/s-1 and in most of the ranges of acceleration. The interpretation of the results suggests that space affected the physical demand of the player

Identification of efficient subgame-perfect Nash equilibria in a class of differential games

The original publication is available at www.springerlink.comWe present a method for the characterization of subgameperfect Nash equilibria being Pareto efficient in a class of differential games. For that purpose, we propose a new approach based on new necessary and sufficient conditions for computing subgame-perfect Nash equilibria.Publicad

Validación del Cuestionario de Autoevaluación de la Creatividad en la Enseñanza Universitaria CACEU-2010

La creatividad es un vector formativo de la enseñanza y de las relaciones entre estudiantes y profesores en la Educación Superior. A tal fin, el Cuestionario de Autoevaluación de la Creatividad en la Enseñanza Universitaria (CACEU-2010) se ha diseñado para conocer cómo comprenden los profesores universitarios la creatividad aplicada a su enseñanza y facilitar su autoevaluación. Se estructuró como una escala de autoinforme, conformada por 44 ítemes. Se estudió la validez de contenido, realizada por jueces expertos. La fiabilidad se obtuvo con el método Alpha de Cronbach, y el parámetro obtuvo valores entre 0,70 y 0,94 para las diferentes subescalas utilizadas

Alimentación de modelos cuantitativos con información subjetiva: aplicación Delphi en la elaboración de un modelo de imputación del gasto turístico individual en Catalunya

El presente artículo presenta un estudio realizado para el Institut d'Estadística de Catalunya, donde se ha aplicado una técnica que trabaja con información subjetiva (el Método Delphi) para obtener unos datos que puedan ser empleados en la alimentación parcial de un modelo matemático, que se nutre principalmente de datos estadísticos (objetivos), con el fin de incrementar la utilidad global del modelo. El artículo justifica la utilización en determinadas circunstancias de la información subjetiva, describe el método Delphi y plantea una serie de proposiciones referentes a la utilidad, empleo y mejora de esta técnica que se ven refrendadas en el caso expuesto

On coincidence of feedback and global Stackelberg equilibria in a class of differential games

This paper shows for a class of differential games that the global Stackelberg equilibrium (GSE) coincides with the feedback Stackelberg equilibrium (FSE), although the GSE assumes that the leader/regulator an- nounces at the initial time the regulatory instrument rule she will follow for the rest of the game, while in the FSE, the regulator at any time chooses the optimal level of the regulatory instrument rate. This coincidence is based on the fact that the FSE is calculated using dynamic programming what implies that although the regulator chooses the regulatory instrument rate level that maximizes social welfare, the first-order condition for the maximization of the right-hand side of the Hamilton-Jacobi-Bellman equa- tion implicitly defines a rule for the regulatory instrument. Then, as the regulatory instrument rule de- fined by the FSE implements the efficient outcome as the GSE does, the rules defined by both equilibria must be the same. In the second part of the paper, we check that this is the case for two examples. The first is an operations research model, while the second is an economic model. The first example fits in a linear-state differential game structure, while the second example presents a linear-quadratic specifica- tion. In both cases the regulatory instrument rules for both equilibria (GSE and FSE) are calculated and identical expressions are obtained.Agencia Estatal de Investigación (AEI) y la Junta de Castilla y León (projects ECO2017-82227-P , VA105G18 y VA169P20, respectivamente) los dos últimos co-financiados por fondos FEDER (UE)

Detection of a putative TetR-like gene related to Mycobacterium bovis BCG growth in cholesterol using a gfp-transposon mutagenesis system

In vitro transposition is a powerful genetic tool for identifying mycobacterial virulence genes and studying virulence factors in relation to the host. Transposon shuttle mutagenesis is a method for constructing stable insertions in the genome of different microorganisms including mycobacteria. Using an IS1096 derivative, we have constructed the Tngfp, a transposon containing a promoterless green fluorescent protein (gfp) gene. This transposon was able to transpose randomly in Mycobacterium bovis BCG. Bacteria with a single copy of the gfp gene per chromosome from an M. bovis BCG::Tngfp library were analyzed and cells exhibiting high levels of fluorescence were detected by flow cytometry. Application of this approach allowed for the selection of a mutant, BCG_2177c::Tngfp (BCG-Tn), on the basis of high level of long-standing fluorescence at stationary phase. This BCG-Tn mutant showed some particular phenotypic features compared to the wild type strain, mainly during stationary phase, when cholesterol was used as a sole carbon source, thus supporting the relationships of the targeted gene with the regulation of cholesterol metabolism in this bacteria. This approach showed that Tngfp is a potentially useful tool for studying the involvement of the targeted loci in metabolic pathways of mycobacteria

New method to characterize subgame-perfect Nash equilibria in differential games

The original publication is available at www.springerlink.comIn this paper, we present a method for computing Nash equilibria in feedback strategies. This method gives necessary and sufficient conditions to characterize subgame perfect equilibria by means of a system of quasilinear partial differential equations. This characterization allows one to know explicitly the solution of the game in some cases. In other cases, this approach makes a qualitative study easier. We apply this method to nonrenewable resource games.Publicad

A fast and cost-effective approach to develop and map EST-SSR markers: oak as a case study

Background: Expressed Sequence Tags (ESTs) are a source of simple sequence repeats (SSRs) that can be used to develop molecular markers for genetic studies. The availability of ESTs for Quercus robur and Quercus petraea provided a unique opportunity to develop microsatellite markers to accelerate research aimed at studying adaptation of these long-lived species to their environment. As a first step toward the construction of a SSR-based linkage map of oak for quantitative trait locus (QTL) mapping, we describe the mining and survey of EST-SSRs as well as a fast and cost-effective approach (bin mapping) to assign these markers to an approximate map position. We also compared the level of polymorphism between genomic and EST-derived SSRs and address the transferability of EST-SSRs in Castanea sativa (chestnut). Results: A catalogue of 103,000 Sanger ESTs was assembled into 28,024 unigenes from which 18.6% presented one or more SSR motifs. More than 42% of these SSRs corresponded to trinucleotides. Primer pairs were designed for 748 putative unigenes. Overall 37.7% (283) were found to amplify a single polymorphic locus in a reference fullsib pedigree of Quercus robur. The usefulness of these loci for establishing a genetic map was assessed using a bin mapping approach. Bin maps were constructed for the male and female parental tree for which framework linkage maps based on AFLP markers were available. The bin set consisting of 14 highly informative offspring selected based on the number and position of crossover sites. The female and male maps comprised 44 and 37 bins, with an average bin length of 16.5 cM and 20.99 cM, respectively. A total of 256 EST-SSRs were assigned to bins and their map position was further validated by linkage mapping. EST-SSRs were found to be less polymorphic than genomic SSRs, but their transferability rate to chestnut, a phylogenetically related species to oak, was higher. Conclusion: We have generated a bin map for oak comprising 256 EST-SSRs. This resource constitutes a first step toward the establishment of a gene-based map for this genus that will facilitate the dissection of QTLs affecting complex traits of ecological importance

Tetrahydropyrazolo[1,5-a]Pyrimidine-3-Carboxamide and N-Benzyl-6′,7′-Dihydrospiro[Piperidine-4,4′-Thieno[3,2-c]Pyran] analogues with bactericidal efficacy against Mycobacterium tuberculosis targeting MmpL3

Mycobacterium tuberculosis is a major human pathogen and the causative agent for the pulmonary disease, tuberculosis (TB). Current treatment programs to combat TB are under threat due to the emergence of multi-drug and extensively-drug resistant TB. As part of our efforts towards the discovery of new anti-tubercular leads, a number of potent tetrahydropyrazolo[1,5-a]pyrimidine-3-ca​rboxamide(THPP) and N-benzyl-6′,7′-dihydrospiro[piperidine-4,​4′-thieno[3,2-c]pyran](Spiro) analogues were recently identified against Mycobacterium tuberculosis and Mycobacterium bovis BCG through a high-throughput whole-cell screening campaign. Herein, we describe the attractive in vitro and in vivo anti-tubercular profiles of both lead series. The generation of M. tuberculosis spontaneous mutants and subsequent whole genome sequencing of several resistant mutants identified single mutations in the essential mmpL3 gene. This ‘genetic phenotype’ was further confirmed by a ‘chemical phenotype’, whereby M. bovis BCG treated with both the THPP and Spiro series resulted in the accumulation of trehalose monomycolate. In vivo efficacy evaluation of two optimized THPP and Spiro leads showed how the compounds were able to reduce >2 logs bacterial cfu counts in the lungs of infected mice