7 research outputs found
Costs of a school-based dental mobile service in South Africa
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Avenues and Barriers to Access of Services for Immigrant Elders: State and Local Policies for OAA Units on Aging
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Drug Strategies Targeting CYP51 in Neglected Tropical Diseases
- Author
- ABalkis M. M.
- Al-Abdely H. M.
- Andrade S. G.
- Andriani G.
- Andriani G.
- Aoyama Y.
- Aoyama Y.
- Aoyama Y.
- Aoyama Y.
- Aquilino C.
- Baldwin B. C.
- Bard M.
- Baroni A.
- Becher R.
- Bellamine A.
- Bellamine A.
- Bennett F.
- Berman J. D.
- Berman J. D.
- Bettiol E.
- Bird C. W.
- Bode H. B.
- Brezna B.
- Buckner F.
- Buckner F.
- Buckner F. S.
- Buckner F. S.
- Buckner F. S.
- Buckner F. S.
- Cacciapuoti A.
- Calvet C. M.
- Camandaroba E. L.
- Cancado J. R.
- Castelli M. V.
- Castro J. A.
- Chagas C.
- Chau A. S.
- Chen C.-K.
- Chen C.-K.
- Chennamaneni N. K.
- Choi J. Y.
- Choi J. Y.
- Choy J. W.
- Clayton J.
- Coppens I.
- Coppens I.
- Corrales M.
- Coste A.
- Coura J. R.
- Courtney K. D.
- Croft S. L.
- Dandapani S.
- de Macedo-Silva S. T.
- de Souza W.
- De Vita D.
- DeLano W. L.
- Desmond E.
- Diaz-Guerra T. M.
- DiDomenico B.
- Diniz Lde F.
- Doyle P. S.
- Dunkel N.
- El-Sayed N. M.
- Emad M.
- Engel J. C.
- Ferraz M. L.
- Filardi L. S.
- Firooz A.
- Fischer R.
- Fischer R. T.
- Friese G.
- Friggeri L.
- Frye L. L.
- Gangneux J. P.
- Geber A.
- Geronikaki A.
- Gibbons G. F.
- Girois S. B.
- Goad L. J.
- Greenberg R. N.
- Guedes P. M.
- Gunatilleke S. S.
- Gupta A. K.
- Hardwick J. P.
- Hargrove T. Y.
- Hargrove T. Y.
- Hargrove T. Y.
- Hargrove T. Y.
- Heeres J.
- Heeres J.
- Heeres J.
- Heeres J.
- Herbrecht R.
- Hoekstra W. J.
- Hossain M. A.
- Howard S. J.
- Howard S. J.
- Hucke O.
- Jackson C. J.
- Jensen-Pergakes K. L.
- Ji H.
- Jun Yong Choi
- Karp J. E.
- Keber R.
- Keenan M.
- Keenan M.
- Keenan M.
- Keenan M.
- Keiser M. J.
- Kelly S. L.
- Kelly S. L.
- Koga H.
- Kohl N. E.
- Kohl W.
- Konkle M. E.
- Kraus J. M.
- Kraus J. M.
- Lackner T. E.
- Lamb D. C.
- Larissa M. Podust
- Lee B. Y.
- Lennon I. C.
- Lepesheva G. I.
- Lepesheva G. I.
- Lepesheva G. I.
- Lepesheva G. I.
- Lepesheva G. I.
- Lewis M. D.
- Li H.
- Li X.
- Liendo A.
- Litton J. K.
- Mann P. A.
- Marichal P.
- Martin-Iguacel R.
- Mejia A. M.
- Mellado E.
- Mellado E.
- Mellado E.
- Mellinghoff I. K.
- Miles M. A.
- Mishra J.
- Molina I.
- Molina J.
- Monk B. C.
- Moraes C. B.
- Moreno M.
- Morio F.
- Moss G. P.
- Murta S. M.
- Musiol R.
- Nagano S.
- Nasser Eddine A.
- Navin T. R.
- Nelson D. R.
- Nes C. R.
- Nes W. D.
- Niwano Y.
- Nomeir A. A.
- Nwaka S.
- Ohkanda J.
- Ortiz de Montellano P. R.
- Paiva J. A.
- Paniz Mondolfi A. E.
- Parish E. J.
- Patra T.
- Pearson A.
- Perea S.
- Perez-Moreno G.
- Pfaller M. A.
- Pietila M. P.
- Pinazo M.-J.
- Pinto e Silva A. T.
- Pitisuttithum P.
- Plempel M.
- Plempel M.
- Pochapsky T. C.
- Podust L. M.
- Podust L. M.
- Podust L. M.
- Podust L. M.
- Pont A.
- Pont A.
- Posteraro B.
- Poulos T. L.
- Raad I. I.
- Raederstorff D.
- Raederstorff D.
- Raederstorff D.
- Rafferty S. W.
- Rangel H.
- Rees H. H.
- Rezen T.
- Richardson K.
- Risley J. M.
- Roberts C. W.
- Rodero L.
- Rodrigues J. C.
- Rodriguez-Tudela J. L.
- Russi A. J.
- Sakariassen K. S.
- Sanchez-Sancho F.
- Sanderson J. T.
- Sanglard D.
- Sanglard D.
- Schiller D. S.
- Schilling S.
- Schlichting I.
- Selmecki A.
- Sen K.
- Shakya N.
- Shakya N.
- Shang N.
- Sheehan D. J.
- Shyadehi A. Z.
- Sionov E.
- Sionov E.
- Slaven J. W.
- Snelders E.
- Snelders E.
- Soeiro Mde N.
- Strushkevich N.
- Summons R. E.
- Suryadevara P. K.
- Taxvig C.
- Teston A. P.
- Timpel C.
- Toledo M. J.
- Troke P. F.
- Trosken E. R.
- Trzaskos J.
- Trzaskos J. M.
- Urbina J. A.
- Urbina J. A.
- Urbina J. A.
- Urbina J. A.
- Urbina J. A.
- Urbina J. A.
- Urbina J. A.
- Urbina J. A.
- Urbina J. A.
- van der Linden J. W.
- Venkateswarlu K.
- Vermeulen E.
- Verweij P. E.
- Verweij P. E.
- Vieira D. F.
- Villalta F.
- Villarreal D.
- Viotti R.
- Visvesvara G. S.
- Volkman J. K.
- von Kries J. P.
- Warrilow A. G.
- Wheat L. J.
- Wheat L. J.
- White J. M.
- William R. Roush
- Xiao L.
- Zeiman E.
- Zhou W.
- Zijlstra E. E.
- Zingales B.
- Zingales B.
- Zirngibl L.
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- Field of study
Gene-deleted live-attenuated Trypanosoma cruzi
- Author
- Ajioka J
- Allaoui A
- Andrade ZA
- Annoura T
- Araujo AF
- Arturo Ferreira
- Atwood JA
- Bafica A
- Barrio AB
- Basombrio MA
- Basombrio MA
- Basombrio MA
- Basombrio MA
- Basombrio MA
- Basombrio MA
- Basombrio MA
- Basso B
- Bastos CJ
- Bern C
- Bestetti RB
- Bouvier LA
- Bustamante JM
- Caler EV
- Castro JA
- Cazorla SI
- Cazorla SI
- Cazorla SI
- Cecilia Pérez Brandán
- Chhajer R
- Clayton CE
- Coburn CM
- Collins MH
- Constant S
- Cooper R
- Cordova E
- Corrales M
- Cruz A
- Cruz AK
- Curto Mde L
- DaRocha WD
- Davoudi N
- Davoudi N
- de Jesus AR
- de Souza FS
- de Souza W
- Dey R
- Dias JC
- Diez M
- DosReis GA
- Dumonteil E
- Duncan R
- Eickhoff CS
- Estrada-Franco JG
- Fernando J Sánchez-Valdéz
- Ferreira V
- Ferreira V
- Fiorelli AI
- Fiuza JA
- Fontanella GH
- Foulds KE
- Gannavaram S
- Gannavaram S
- Gannavaram S
- Garcia S
- Giddings OK
- Gluenz E
- Golgher D
- Gomez LE
- Gravina HD
- Guinazu N
- Gurtler RE
- Gurtler RE
- Hoft DF
- Hotez P
- Hotez PJ
- Hotez PJ
- Hotez PJ
- Jackson Y
- Junqueira C
- Kalil J
- Kayama H
- Kelly JM
- Khan SM
- Kierszenbaum F
- Kuehn CC
- Kurup SP
- Labriola C
- Leguizamon MS
- Lima MT
- MacRae JI
- Manning-Cela R
- Maranon C
- Martinez-Calvillo S
- Matos MN
- Meeusen EN
- Menezes H II
- Metz DP
- Miguel Ángel Basombrío
- Morell M
- Mukherjee A
- Nobrega AA
- Nozaki T
- Padilla AM
- Parodi C
- Pellegrini A
- Pena-Diaz J
- Perez Brandan C
- Perez-Fuentes R
- Pizzi T
- Pérez brandán C
- Quijano-Hernandez IA
- Ragone PG
- Ramirez G
- Rassi A
- Rassi A
- Revelli S
- Revelli S
- Rigato PO
- Robinson HL
- Rodrigues AA
- Rodrigues MM
- Rosenberg CS
- Saljoughian N
- Sanchez-Valdez FJ
- Santori FR
- Schijman AG
- Schijman AG
- Schmunis G
- Schmunis GA
- Schofield CJ
- Selvapandiyan A
- Sosoniuk E
- Spring M
- Sánchez Valdéz F
- Taibi A
- Tarleton RL
- Tarleton RL
- Tarleton RL
- Tarleton RL
- Vago AR
- Vaidian AK
- Valck C
- VanBuskirk KM
- Vuola JM
- WHO
- Xu D
- Yoshida N
- Zago MP
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Outcomes after perioperative SARS-CoV-2 infection in patients with proximal femoral fractures: an international cohort study
- Author
- A'Court J
- Aawsaj Y
- Abbadessa F
- Abbas A
- Abbott S
- Abdalaziz H
- Abdalla M
- Abdeh L
- Abdelsaid K
- Abdou H
- Abdul-Jabar H
- Abood A
- Abou-Foul AK
- Abrate A
- Abu-Nayla I
- Abual-Rub Z
- Abuown A
- Adamec A
- Adegbola S
- Ademuyiwa AO
- Advani R
- Aftab R
- Agarwal A
- Agarwal K
- Aggarwal A
- Aghababyan K
- Agilinko J
- Agrawal S
- Ahad S
- Ahmad Y
- Ahmed Elamin H
- Ahmed I
- Ahmeidat A
- Akhtar MA
- Al Ameer E
- Al-mukhtar A
- Al-omishy H
- Al-Samaraee A
- Al-Sukaini A
- Al-Yaseen M
- Aladeojebi A
- Alanbuki A
- Alderson D
- Aldridge K
- Alexander ME
- Alga A
- Ali M
- Ali Mahmoud F
- Ali S
- Allana A
- Allen M
- Almeida AC
- Almond M
- Alotaibi M
- Alqallaf A
- Alsakkaf M
- Alser O
- Alser O
- Altomare DF
- Alves R
- Alwadiya A
- Alzetani A
- Amaral MJ
- Ambler GK
- Ameerally P
- Anania G
- Anazor F
- Anderson C
- Andrade R
- Andreani SM
- Andronic A
- Aneke IA
- Angamuthu N
- Anjarwalla N
- Antar M
- Anthoney J
- Anton-Eguia BT
- Antunes J
- Apampa AA
- Aragon Achig EJ
- Archer JE
- Arigoni M
- Arkani S
- Armao T
- Arminio A
- Arnaud AP
- Arrieta M
- Asaad P
- Ascensao J
- Ashcroft J
- Asher S
- Askari A
- Athayde Nemesio R
- Augestad KM
- Aujayeb A
- Aujayeb A
- Awadallah M
- Ayeni F
- Ayorinde J
- Azevedo P
- Baban C
- Babawale O
- Babu BHB
- Bacarese-Hamilton J
- Bacarese-Hamilton T
- Badran A
- Bagouri E
- Baig M
- Baig MMAS
- Baker M
- Baker OJ
- Balaguer-Castro M
- Balakrishnan A
- Balasubramaniam D
- Balasubramanian SP
- Balau P
- Baldwin AJ
- Ballabio M
- Ballantyne K
- Baltazar G
- Bandyopadhyay S
- Bankhad-Kendall B
- Bankhead-Kendall B
- Bankhead-Kendall B
- Baquedano M
- Barbe Y
- Barbier L
- Barmayehvar B
- Barmpagianni C
- Barret E
- Barry C
- Bartsch A
- Basgaran A
- Basha A
- Bashkirova V
- Baskaran D
- Bateman A
- Bath MF
- Baumber R
- Baxter Z
- Bayer J
- Beak P
- Beamish AJ
- Begona E
- Bekheit M
- Belcher E
- Bellis C
- Beltran-Miranda P
- Ben-Sassi A
- Bence M
- Benitez-Linero I
- Benjamin MW
- Benson RA
- Bernal-Sprekelsen JC
- Bernasconi M
- Bevan K
- Bhalla A
- Bhangu A
- Bhangu A
- Bhangu A
- Bhasin S
- Bhaskar Pala RR
- Bhatia K
- Bhattacharya S
- Bhojwani D
- Bhutiani N
- Bierman W
- Bisagni P
- Blair J
- Blake I
- Blanco J
- Blanco-Colino R
- Blas Laina JL
- Blasco-Moreu J
- Blasco-Torres L
- Bleibleh S
- Blencowe NS
- Bloom O
- Blundell C
- Boal M
- Board T
- Bobak P
- Bodla AS
- Boeckxstaens A
- Boeker C
- Bond-Smith G
- Booth K
- Bordenave M
- Borghi F
- Borgstein ABJ
- Bosanquet D
- Bosch KD
- Bouche PA
- Bourke G
- Bowen D
- Branco C
- Brar A
- Brathwaite CEM
- Bravo A Minaya
- Breda D
- Breen K
- Breen KA
- Breik O
- Brennan C
- Brennan P
- Bretherton C
- Bretherton C
- Brian E
- Britton E
- Brown A
- Brown BC
- Brown O
- Brown O
- Brown S
- Brown SR
- Brown V
- Brunelli A
- Brunt A
- Buarque I Lima
- Burahee A
- Burke JR
- Byrne J
- Byrne MHV
- Cabeleira A
- Cadersa A
- Cagigal Ortega EP
- Caja Vivancos P
- Callahan MP
- Callan R
- Calvo Rey A
- Camacho C
- Camacho-Carrasco P
- Campain N
- Campbell R
- Campuzano-Bitterling B
- Canhoto C
- Cao H
- Capitan-Morales L
- Capitelli-McMahon H
- Caputo M
- Carcoforo P
- Cardoso N
- Cardoso N
- Cardoso P
- Cardoso P
- Carlos W
- Carmichael H
- Carreras-Castaner A
- Carrillo-Rivas M
- Carter J
- Caruana E
- Carvalho L
- Castano-Leon AM
- Castellanos J
- Catala Bauset JC
- Cathala N
- Cathelineau X
- Cato LD
- Catton A
- Cernei C
- Cervera I
- Chakrabortee S
- Chan CD
- Chan CH
- Chan M
- Chase T
- Chatterji S
- Chaudhry D
- Chaudhry D
- Chauhan G
- Chebaro A
- Chek Syed Nong SAH
- Chelva R
- Chen F
- Cheng D
- Chetty G
- Cheung J
- Chia Z
- Chiarpenello R
- Chidambaram S
- Chiozza M
- Choron R
- Choudhry A
- Chowdhury M
- Chowdhury S
- Chrastek D
- Christensen MA
- Christoforidis D
- Chu H
- Chui K
- Chung C
- Chung E
- Cianflocca D
- Cioci A
- Ciriello V
- Cirocchi N
- Clancy H
- Clark J
- Clifford R
- Clough E
- Clynch AL
- Cohnert TU
- Coleman NL
- Colino M
- Collaborative COVIDSurg
- Collera P
- Collier T
- Collis J
- Colombo F
- Colquhoun A
- Colvin HV
- Combellack T
- Connolly H
- Conso C
- Constable J
- Cooper Z
- Cordonnier A
- Cornish J
- Correia S
- Costa M
- Costeira B
- Cotoia A
- Cotsoglou C
- Coughlin P
- Crego-Vita D
- Cresner R
- Crichton A
- Crichton R
- Cros B
- Cross GWV
- Cuming T
- Cumpstey A
- Cunha C
- Cunha MF
- Cunningham Y
- Cuschieri J
- Cuthbert R
- Cymes W
- D'Agruma M
- Daadipour A
- Dalgleish S
- Daliya P
- Dalmasso E
- Daniele A
- Daniels IR
- Das R
- Dasa M
- Dass D
- Dauer MDE
- Davenport D
- Davidson B
- Davidson GH
- Davidson GH
- Davies E
- Davies RJ
- Davies-Jones G
- Davis NF
- Davison S
- Dawe N
- Dawson AC
- Dawson BE
- De Barros J
- de Castro Rubio Garcia E
- De Coster J
- De Gheldere C
- de la Manzanara Cano Lopez CA
- De la Rosa-Estadella M
- de Lacy FB
- De Marchi J
- De Oliveira Lopez AL
- De Vries JPPM
- Dean B
- Dean H
- Deglurkar I
- Dehal A
- del Toro Lopez MD
- Delgado Fernandez J
- Dellonder Frigole J
- Demetriou C
- Denning A
- Denning M
- Desai A
- Desai A
- Dewan V
- Dhaif F
- Di Chiara F
- Di Giuseppe M
- Di Saverio S
- Di Taranto G
- Diaz Del Gobbo R
- Diaz Pena P
- Diaz J
- Diaz J
- Dickson K
- Divecha H
- Dixon J
- Doe M
- Domenech J
- Domingues JC
- Domingues JC
- Doorgakant A
- Dos Santos Carregal L
- Dott C
- Doulias T
- Dovell G
- Drake T
- Drane A
- Duchateau N
- Duck E
- Dudek J
- Duff S
- Duggleby L
- Dunn J
- Dunne N
- Dunning J
- Dunstan M
- Duque M
- Duran-Munoz-Cruzado VM
- Durrani A
- Durst AZED
- Dvorkin LS
- Eardley N
- Eberbach H
- Ebrahim A
- Edmondson R
- Edwards J
- Edwards J
- Egan RJ
- Egglestone A
- Eibinger N
- Eiriz Fernandez C
- El Amrani M
- El Drubi Vega S
- El Hechi M
- El Kafsi J
- El Moheb M
- El-Hasani S
- Elhadi M
- Elhusseini M
- Elkadi H
- Elliott L
- Elmaleh N
- Emerson H
- Emmerson O
- Emslie K
- Enemosah I
- Engel J
- English C
- Enjuto D
- Erdle B
- Eriberto F
- Erridge S
- Escartin J
- Escobar D
- Espino Segura-Illa M
- Estaire Gomez M
- Esteban Sinovas O
- Evans J
- Evans J
- Evans JP
- Evans R
- Exley R
- Farik S
- Farre Font R
- Farrell T
- Fathelbab MSAT
- Faulkner G
- Fawi H
- Fayad A
- Fediuk M
- Fell A
- Ferguson D
- Ferguson H
- Fernandez Bernabe P
- Fernandez Camunas A
- Fernandez-Colorado A
- Fernandez-Marin MR
- Ferrero Herrero E
- Finch JG
- Fine N
- Fiore M
- Fisher A
- Fitzgerald JE
- Flannery O
- Flatman M
- Flindall I
- Flores Clotet R
- Folorunso A
- Ford D
- Ford S
- Ford S
- Forlani S
- Foster L
- Fountain DM
- Fowler GE
- Freedman J
- Freijeiro M
- Freystaetter K
- Fu H
- Fudulu DP
- Fuks D
- Fusai G
- Gabr A
- Gagliano A
- Gainza A
- Gaitanidis A
- Galhoum M
- Galipienso Eri M
- Gallagher B
- Gallagher P
- Gallo G
- Gammeri E
- Ganau M
- Garces Garcia R
- Garcia de Cortazar U
- Garcia Egea J
- Garcia Gutierrez JJ
- Garcia Montesino JD
- Garcia Opere G
- Garcia Perez D
- Garcia Santos EP
- Garcia Villar O
- Garcia-Borda J
- Gardner A
- Garner M
- Garnero A
- Garrido R
- Garrido S
- Garrido-Ondono S
- Gasset-Teixidor A
- Gasulla-Rodriguez A
- Gaujoux S
- Gaunt A
- Gelarda E
- George K
- Georgiades F
- Georgopoulou N
- Gerogiannis I
- Ghanbari A
- Ghattaura H
- Ghobrial M
- Ghosh D
- Ghosh K
- Giblin A
- Gil-Albarova O
- Gilabert Estelles J
- Gill C
- Gill DF
- Gilliland J
- Giraudo G
- Gisbertz SS
- Giuffrida MC
- Glasbey JC
- Gnanachandran C
- Godbole C
- Godinho M
- Gohil K
- Gokcen E
- Gomes GMA
- Gomes H
- Gomez Cruzado Fernandez L
- Gomez Diaz CJ
- Gomez Suarez J
- Gomez P
- Gomez-Rosado J
- Gonzalez De Miguel M
- Gonzalez J
- Gossot D
- Goubran A
- Gowda M
- Goyal A
- Gracia I
- Gradinariu G
- Grainger T
- Granieri S
- Green S
- Greenhalgh MS
- Griffin XL
- Griffiths E
- Griffiths E
- Grigoroiu M
- Grimaldi Di Maria S
- Grimley E
- Groot G
- Guardia N
- Guariglia CA
- Guerreiro P
- Guha S
- Guimaraes A
- Gujjuri RR
- Gusani N
- Habeeb A
- Habeebullah A
- Hadfield JN
- Hagger R
- Hainsworth A
- Hakami I
- Hakmi H
- Halkias C
- Halkias C
- Hall J
- Halliday E
- Hamady Z
- Hamilton E
- Hammond J
- Hampton M
- Handa S
- Hanna N
- Hannah A
- Hansen L
- Hanson A
- Haq I
- Hardie C
- Hardie J
- Harries R
- Harris G
- Harrison EM
- Harrison EM
- Hart C
- Hasan MT
- Hasan R
- Hashem M
- Hassan A
- Hassan M
- Hatzantonis C
- Haugstvedt AF
- Hawkin P
- Hazelton J
- Heckburn R
- Heer B
- Henegouwen van Berge MI
- Hennessy EA
- Henriques Marujo D
- Henriques P
- Henriques P
- Henry A
- Henshall DE
- Heritage E
- Hernandez E
- Hernandez I
- Herrera-Merino N
- Hettige R
- Higgs S
- Hill A
- Hill G
- Hilley A
- Hine T
- Hing C
- Hirji SA
- Hirri F
- Hirsch H
- Hitchman L
- HKruijff S
- Ho B
- Ho M
- Holler E
- Holme T
- Holroyd D
- Hope N
- Hopkins J
- Hormis AP
- Horvath S
- Hosny S
- Hossain F
- Hossain N
- Houston R
- Howden D
- Hudson VE
- Huecas-Martinez M
- Hughes I
- Hughes JL
- Humphreys L
- Hunt I
- Hunt J
- Hussein KMA
- Hutchinson P
- Hutchinson PJ
- Ibrahim Aboelkassem A
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- Publication venue
- 'BMJ'
- Publication date
- 01/01/2021
- Field of study
Objectives Studies have demonstrated high rates of mortality in people with proximal femoral fracture and SARS-CoV-2, but there is limited published data on the factors that influence mortality for clinicians to make informed treatment decisions. This study aims to report the 30-day mortality associated with perioperative infection of patients undergoing surgery for proximal femoral fractures and to examine the factors that influence mortality in a multivariate analysis. Setting Prospective, international, multicentre, observational cohort study. Participants Patients undergoing any operation for a proximal femoral fracture from 1 February to 30 April 2020 and with perioperative SARS-CoV-2 infection (either 7 days prior or 30-day postoperative). Primary outcome 30-day mortality. Multivariate modelling was performed to identify factors associated with 30-day mortality. Results This study reports included 1063 patients from 174 hospitals in 19 countries. Overall 30-day mortality was 29.4% (313/1063). In an adjusted model, 30-day mortality was associated with male gender (OR 2.29, 95% CI 1.68 to 3.13, p80 years (OR 1.60, 95% CI 1.1 to 2.31, p=0.013), preoperative diagnosis of dementia (OR 1.57, 95% CI 1.15 to 2.16, p=0.005), kidney disease (OR 1.73, 95% CI 1.18 to 2.55, p=0.005) and congestive heart failure (OR 1.62, 95% CI 1.06 to 2.48, p=0.025). Mortality at 30 days was lower in patients with a preoperative diagnosis of SARS-CoV-2 (OR 0.6, 95% CI 0.6 (0.42 to 0.85), p=0.004). There was no difference in mortality in patients with an increase to delay in surgery (p=0.220) or type of anaesthetic given (p=0.787). Conclusions Patients undergoing surgery for a proximal femoral fracture with a perioperative infection of SARS-CoV-2 have a high rate of mortality. This study would support the need for providing these patients with individualised medical and anaesthetic care, including medical optimisation before theatre. Careful preoperative counselling is needed for those with a proximal femoral fracture and SARS-CoV-2, especially those in the highest risk groups. Trial registration number NCT0432364
Mortality after surgery in Europe: a 7 day cohort study
- Author
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- Acan I
- Adams D
- Adams T
- Adanic M
- Adolfsson A
- Afonso O
- Afshari A
- Agarwal B
- Agnic I
- Aguado DN
- Ahern R
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- Aignatoaie M
- Akotia N
- Akouds E
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- Alagarsamy F
- Alameda LE
- Alaspää A
- Albalad DD
- Albaladejo P
- Albante A
- Alberdi F
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- Alcaide CM
- Alcantud JF
- Aldecoa C
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- Aleixandre IS
- Aleksic D
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- Andersen JD
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- Bona F
- Bonet A
- Boninsegna D
- Bonnet A
- Bonnet F
- Bonnett A
- Bonnington S
- Bonnländer G
- Borchers F
- Bordeianu C
- Borja MM
- Borovsak Z
- Borrat X
- Bosinceanu D
- Botas C
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- Božic A
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- Brattström O
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- Buttera S
- Bártolo A
- Béclère A
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- Canalechevarria AM
- Candi GM
- Cantarini E
- Capel YJ
- Capková J
- Capone M
- Capuzzo M
- Carballal FF
- Carballo CL
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- Cartlidge D
- Carvalho A
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- Castiñeiras AP
- Castrillón S
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- Castro MR
- Castro NM
- Catalán M
- Cecconi M
- Centonze C
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- Cerny V
- Cerutti E
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- Cervera Montes M
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- Chew M
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- Christ S
- Christie I
- Christopoulos C
- Cimadevilla B
- Ciobanu A
- Cirillo V
- Ciubotaru R
- Clanchet M
- Clarke A
- Clausen NG
- Clauwaert C
- Claxton A
- Clouva Molyvdas PM
- Cocu S
- Codreanu M
- Collantes E
- Collard E
- Collareta M
- Collates AF
- Collin V
- Collins D
- Collins H
- Collyer T
- Concostrina Mde L
- Conway D
- Copley E
- Copotoiu R
- Copotoiu SM
- Coppini R
- Corneci D
- Corner V
- Corradetti F
- Correia C
- Corsini LM
- Cortes JG
- Cortés AF
- Costagliola R
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- Cremades M
- Crespo BI
- Crespo Mdel R
- Crespo P
- Cristina MV
- Crooks N
- Crowley S
- Csomos A
- Csüllög E
- Cuarental A
- Cubillos DN
- Cupitt J
- Currie V
- Cvachovec K
- Czeslick E
- Cíková A
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- Damian M
- Damjanovska M
- Damster S
- Danira V
- Das D
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- Day C
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- de Almeida J
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- de la Lastra M
- de la Torre PA
- de Maeyer AG
- de Meneses H
- De Michele M
- De Neve N
- de Prat IC
- de Quevedo SA
- de Rabago RB
- De Rudnicki S
- De Simone M
- de Sousa AC
- de Sousa M
- De Wit E
- de Zayas RS
- Debelic D
- Debernardi F
- Del Olmo M
- Delgado FC
- Delgado HG
- Delgado TR
- Delic N
- Dell'unto S
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- Della Rocca G
- Della Rocca G
- Demars N
- Dempsey G
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- Dennesen P
- Derumeaux P
- Desbordes J
- Desikan S
- Deutsch PA
- Di Mauro P
- Di Noto A
- Diaconescu C
- Diaz A
- Diaz Boladeras RM
- Diaz DS
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- Dinescu SA
- Dinu M
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- Dokka V
- Domínguez D
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- Doyle Y
- Drab M
- Dragoumanis C
- Dragulescu D
- Dražen B
- Drenjancevic IH
- Drescher J
- Dresden C
- Dropulic N
- Druwé P
- Dubois Vallaud D
- Dufur M
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- Dumenil AS
- Dunne K
- Duque P
- Durán MV
- Duzel V
- Dušanka K
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- Díaz TD
- Díez EP
- Earnshaw G
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- Elekes E
- Elisei D
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- Ellermaa J
- ElMiloudi F
- Elomaa E
- Elson MZ
- Elvira MA
- Elósegui I
- Engelen WC
- Epure F
- Ercole A
- Erkens U
- Erler I
- Ernst S
- Espinosa E
- Espinosa N
- Esteruelas JA
- Esteva GE
- Esteves F
- Estilita J
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- Fagnoul D
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- Farnia A
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- Feld F
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- Fernández LF
- Fernández PT
- Fernández SR
- Ferrandiz ST
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- Frkovic V
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- Fucecchio I
- Fumagalli R
- Fusari M
- Fuster ML
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- Galambos Z
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- Gandolfi A
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- García PD
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- García Sanz M
- García V
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- Gardin C
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- Gazibegovic N
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- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2012
- Field of study
Background: Clinical outcomes after major surgery are poorly described at the national level. Evidence of heterogeneity between hospitals and health-care systems suggests potential to improve care for patients but this potential remains unconfirmed. The European Surgical Outcomes Study was an international study designed to assess outcomes after non-cardiac surgery in Europe.Methods: We did this 7 day cohort study between April 4 and April 11, 2011. We collected data describing consecutive patients aged 16 years and older undergoing inpatient non-cardiac surgery in 498 hospitals across 28 European nations. Patients were followed up for a maximum of 60 days. The primary endpoint was in-hospital mortality. Secondary outcome measures were duration of hospital stay and admission to critical care. We used χ² and Fisher’s exact tests to compare categorical variables and the t test or the Mann-Whitney U test to compare continuous variables. Significance was set at p<0·05. We constructed multilevel logistic regression models to adjust for the differences in mortality rates between countries.Findings: We included 46 539 patients, of whom 1855 (4%) died before hospital discharge. 3599 (8%) patients were admitted to critical care after surgery with a median length of stay of 1·2 days (IQR 0·9–3·6). 1358 (73%) patients who died were not admitted to critical care at any stage after surgery. Crude mortality rates varied widely between countries (from 1·2% [95% CI 0·0–3·0] for Iceland to 21·5% [16·9–26·2] for Latvia). After adjustment for confounding variables, important differences remained between countries when compared with the UK, the country with the largest dataset (OR range from 0·44 [95% CI 0·19 1·05; p=0·06] for Finland to 6·92 [2·37–20·27; p=0·0004] for Poland).Interpretation: The mortality rate for patients undergoing inpatient non-cardiac surgery was higher than anticipated. Variations in mortality between countries suggest the need for national and international strategies to improve care for this group of patients.Funding: European Society of Intensive Care Medicine, European Society of Anaesthesiology
Mortality after surgery in Europe: a 7 day cohort study.
- Author
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- \u160aric JP
- \u160eric J
- \u160imic-Korac N
- \u160imurina T
- \u160ribar A
- \u17dilic A
- \u17dilinc\ue1rov\ue1 V
- \u17duni J
- \u17dupcic M
- \uc1lvaro JL
- \uc5lvarez JT
- \ucd\uf1igo JA
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- Tiainen P
- Tibblin AO
- Tikkerberi A
- Timms G
- Timoneda FL
- Tincu E
- Tindall L
- Tinti C
- Toft P
- Toft P
- Toha AC
- Toivonen J
- Toma\u161evic A
- Tomasevic B
- Tomescu D
- Tomkute G
- Tommasino C
- Tompsett L
- Tomulic K
- Topic J
- Toplice K
- Toretti I
- Tormena M
- Toro JP
- Torrente FM
- Torres BF
- Tosi M
- Tot OK
- Tounou-Akue F
- Tredici S
- Trenkler S
- Triltsch A
- Trodd D
- Tsakas P
- Tsirogianni A
- Tucker K
- Tufano R
- Turcanu R
- Turi S
- Turina M
- Turner A
- Tzani V
- Ubre M
- Ungureanu L
- Unterberg M
- Untergehrer G
- Unz\ufae CL
- Ursic T
- Ursu I
- Utrera FA
- V\ue4\ue4r\ue4niemi H
- Vaccarisi E
- Vainio K
- Vajter J
- Vakkala M
- Valc\ue1rcel IE
- Vallejo A
- Vallet B
- van Acker G
- van Bommel J
- van den Berg R
- van der A M
- van der Hoven B
- van Duijn D
- van Klei W
- Van Mossevelde V
- van Obbergh L
- Vanlinthout L
- Vaquer S
- Varela IP
- Vargas MJ
- Vasan R
- Vasanth S
- Vasian H
- Vega JL
- Velasco AR
- Veld B
- Velzeboer F
- Venema A
- Venkatesh S
- Venzera- Azenic D
- Verbeke A
- Vercauteren M
- Verdenelli P
- Verhamme B
- Vezzoli D
- Viarengo V
- Vicari L
- Vicente R
- Vidal FG
- Vidal SG
- Viitanen M
- Vijar K
- Vilardi A
- Villach IR
- Villagran J
- Villen LM
- Vincent JL
- Vincent JL
- Vingsnes SO
- Vinnal M
- Visentin R
- Visk E
- Viskovic N
- Vitor P
- Vizca\uedno M
- Vizcaychipi M
- Vojinovic R
- von Heymann C
- Voulas A
- Vrankovic S
- Vrbanovic V
- Vrettou E
- Vymazal T
- Wadams B
- Wagner B
- Wagner J
- Waife N
- Walder B
- Walker E
- Walker R
- Wallet F
- Walsh H
- Ward G
- Ward S
- Warde B
- Wasmund C
- Waton K
- Watters M
- Webb S
- Weber M
- Weda T
- Wepler U
- Wernerman J
- Wessels K
- Westbrook A
- Westbrook A
- Weyland A
- White N
- White S
- Wickboldt N
- Wiegand-L\uf6hnert C
- Wiese O
- Wigmore T
- Wilde J
- Willars C
- Williams C
- Williams M
- Wilson J
- Wilson R
- Wilson S
- Windsor D
- Winsser L
- Wintzheimer S
- Wittmann M
- Wollaston J
- Wong K
- Wong P
- Woolhead A
- Worton R
- Wright C
- Wright M
- Wyldbore M
- Yemnga B
- Yepes MJ
- Yeung J
- Ytrebo LM
- Zaballos J
- Zabarte M
- Zacharouli D
- Zacharovska A
- Zadrazilova K
- Zafiridis T
- Zahorec R
- Zahorec R
- Zaldibar E
- Zamora JF
- Zandvliet R
- Zantua K
- Zearo E
- Zeba S
- Ziekenhuis A
- Zittling R
- Zocca E
- Zoltowski MK
- Zompanti V
- Zsisku L
- Zunic F
- Zuzan O
- Publication venue
- Publication date
- 01/01/2012
- Field of study