Shear-free rotating inflation

We demonstrate the existence of shear-free cosmological models with rotation and expansion which support the inflationary scenarios. The corresponding metrics belong to the family of spatially homogeneous models with the geometry of the closed universe (Bianchi type IX). We show that the global vorticity does not prevent the inflation and even can accelerate it.Comment: Revtex, 12 pages; to appear in Phys. Rev.

From Fast Oscillations to Circadian Rhythms: Coupling at Multiscale Frequency Bands in the Rodent Subcortical Visual System

This is the final version. Available on open access from Frontiers Media via the DOI in this recordData Availability Statement: The original contributions presented in the study are included in the article/supplementary material, further inquiries can be directed to the corresponding authors.The subcortical visual system (SVS) is a unique collection of brain structures localised in the thalamus, hypothalamus and midbrain. The SVS receives ambient light inputs from retinal ganglion cells and integrates this signal with internal homeostatic demands to influence physiology. During this processing, a multitude of oscillatory frequency bands coalesces, with some originating from the retinas, while others are intrinsically generated in the SVS. Collectively, these rhythms are further modulated by the day and night cycle. The multiplexing of these diverse frequency bands (from circadian to infra-slow and gamma oscillations) makes the SVS an interesting system to study coupling at multiscale frequencies. We review the functional organisation of the SVS, and the various frequencies generated and processed by its neurons. We propose a perspective on how these different frequency bands couple with one another to synchronise the activity of the SVS to control physiology and behaviour.National Science CentreBiotechnology and Biological Sciences Research Council (BBSRC)Higher Education Sprout Project, Taiwan Ministry of EducationTaiwan Ministry of Science and TechnologyTaipei Medical Universit

Shearfree perfect fluids with solenoidal magnetic curvature and a gamma-law equation of state

We show that shearfree perfect fluids obeying an equation of state p=(gamma -1) mu are non-rotating or non-expanding under the assumption that the spatial divergence of the magnetic part of the Weyl tensor is zero.Comment: 11 page

Scalar-field quintessence by cosmic shear: CFHT data analysis and forecasts for DUNE

A light scalar field, minimally or not-minimally coupled to the metric field, is a well-defined candidate for the dark energy, overcoming the coincidence problem intrinsic to the cosmological constant and avoiding the difficulties of parameterizations. We present a general description of the weak gravitational lensing valid for every metric theory of gravity, including vector and tensor perturbations for a non-flat spatial metric. Based on this description, we investigate two minimally-coupled scalar field quintessence models using VIRMOS-Descart and CFHTLS cosmic shear data, and forecast the constraints for the proposed space-borne wide-field imager DUNE.Comment: 7 pages, 4 figures. To appear in proceedings of IRGAC06 (Barcelona, July 06

Principal null directions of perturbed black holes

The properties of principal null directions of a perturbed black hole are investigated. It shown that principal null directions are directly observable quantities characterizing the space-time. A definition of a perturbed space-time, generalizing that given by Stewart and Walker is proposed. This more general framework allows one to include descriptions of a given space-time other than by a pair $(M,g)$ where $M$ is a four-dimensional differential manifold and $g$ a Lorentz metric. Examples of alternative characterizations are the curvature representation of Karlhede and others, the Newman-Penrose representation or observable quantities involving principal null directions. The conditions are studied under which the various alternative choices of observables provide equivalent descriptions of the space-time.Comment: To appear in Class. Quantum Gra

On closed rotating worlds

A new solution for the stationary closed world with rigid rotation is obtained for the spinning fluid source. It is found that the spin and vorticity are locally balanced. This model qualitatively shows that the local rotation of the cosmological matter can be indeed related to the global cosmic vorticity, provided the total angular momentum of the closed world is vanishing.Comment: 10 pages, Revtex, to appear in Phys. Rev. D6

Classification of image distortions in terms of Petrov types

An observer surrounded by sufficiently small spherical light sources at a fixed distance will see a pattern of elliptical images distributed over the sky, owing to the distortion effect (shearing effect) of the spacetime geometry upon light bundles. In lowest non-trivial order with respect to the distance, this pattern is completely determined by the conformal curvature tensor (Weyl tensor) at the observation event. In this paper we derive formulas that allow to calculate these distortion patterns in terms of the Newman-Penrose formalism. Then we represent the distortion patterns graphically for all Petrov types, and we discuss their dependence on the velocity of the observer.Comment: 22 pages, 8 eps-figures; revised version, parts of Introduction and Conclusions rewritte

Monocyte behaviour and tissue transglutaminase expression during experimental autoimmune encephalomyelitis in transgenic CX3CR1gfp/gfp mice

Leukocyte infiltration into the central nervous system (CNS) is a key pathological feature in multiple sclerosis (MS) and the MS animal model experimental autoimmune encephalomyelitis (EAE). Recently, preventing leukocyte influx into the CNS of MS patients is the main target of MS therapies and insight into cell behaviour in the circulation is needed for further elucidation of such therapies. In this study, we aimed at in vivo visualization of monocytes in a time-dependent manner during EAE. Using intravital two-photon microscopy (IVM), we imaged CX3CR1gfp/gfp mice during EAE, visualizing CX3CR1-GFP+ monocytes and their dynamics in the spinal cord vasculature. Our observations showed that intraluminal crawling of CX3CR1-GFP+ monocytes increased even before the clinical onset of EAE due to immunization of the animals. Furthermore, intraluminal crawling remained elevated during ongoing clinical disease. Besides, the displacement of these cells was larger during the peak of EAE compared to the control animals. In addition, we showed that the enzyme tissue transglutaminase (TG2), which is present in CNS-infiltrated cells in MS patients, is likewise found in CX3CR1-GFP+ monocytes in the spinal cord lesions and at the luminal side of the vasculature during EAE. It might thereby contribute to adhesion and crawling of monocytes, facilitating extravasation into the CNS. Thus, we put forward that interference with monocyte adhesion, by e.g. inhibition of TG2, should be applied at a very early stage of EAE and possibly MS, to effectively combat subsequent pathology

Union of the European Phoniatricians' position statement on the exit strategy of phoniatric and laryngological services : staying safe and getting back to normal after the peak of coronavirus disease 2019 (issued on 25th May 2020)

Background The following position statement from the Union of the European Phoniatricians, updated on 25th May 2020 (superseding the previous statement issued on 21st April 2020), contains a series of recommendations for phoniatricians and ENT surgeons who provide and/or run voice, swallowing, speech and language, or paediatric audiology services. Objectives This material specifically aims to inform clinical practices in countries where clinics and operating theatres are reopening for elective work. It endeavours to present a current European view in relation to common procedures, many of which fall under the aegis of aerosol generating procedures. Conclusion As evidence continues to build, some of the recommended practices will undoubtedly evolve, but it is hoped that the updated position statement will offer clinicians precepts on safe clinical practice.Peer reviewe