Diet, faecal pH and colorectal cancer.

We suggest that a lower faecal pH may be correlated with a lower mortality of large-bowel cancer and that faecal pH should always be considered in epidemiological studies on the role of diet in colon carcinogenesis

Microbial fuel cell – A novel self-powered wastewater electrolyser for electrocoagulation of heavy metals

© 2016 The Authors This paper describes the suitability of the Microbial Fuel Cell (MFC) for generation of electrical power with a simultaneous synthesis of active catholyte in the form of caustic solution. The active solution formed inside a terracotta based MFC reactor was a product of self-powered wastewater electrolysis utilizing i) wastewater with added sodium acetate as a carbon source and ii) neat urine. The catholyte solution that has been actively synthesized was harvested and used for precipitation of heavy metals such as: iron, copper and zinc showing its suitability for use in electro-coagulation (electro-flocculation). This proposed alternative approach to self-powered electrocoagulation is based on electrochemically formed caustic catholyte within the inner cathode chamber of the MFC and then used ex situ to form metal hydroxides that precipitate out from heavy metal solutions

Articulating the effect of food systems innovation on the Sustainable Development Goals

Food system innovations will be instrumental to achieving multiple Sustainable Development Goals (SDGs). However, major innovation breakthroughs can trigger profound and disruptive changes, leading to simultaneous and interlinked reconfigurations of multiple parts of the global food system. The emergence of new technologies or social solutions, therefore, have very different impact profiles, with favourable consequences for some SDGs and unintended adverse side-effects for others. Stand-alone innovations seldom achieve positive outcomes over multiple sustainability dimensions. Instead, they should be embedded as part of systemic changes that facilitate the implementation of the SDGs. Emerging trade-offs need to be intentionally addressed to achieve true sustainability, particularly those involving social aspects like inequality in its many forms, social justice, and strong institutions, which remain challenging. Trade-offs with undesirable consequences are manageable through the development of well planned transition pathways, careful monitoring of key indicators, and through the implementation of transparent science targets at the local level

Articulating the effect of food systems innovation on the Sustainable Development Goals

Acknowledgments MH, DM-D, JP, JRB, AH, GDB, CMG, CLM, and KR acknowledge funding from the Commonwealth Scientific and Industrial Research Organisation. PKT, BMC, AJ, and AML acknowledge funding from the CGIAR Research Program on Climate Change, Agriculture and Food Security, which is supported by the CGIAR Trust Fund and through bilateral funding agreements. PP acknowledges funding from the German Federal Ministry of Education and Research for the BIOCLIMAPATHS project.Peer reviewedPublisher PD

Surfactant protein-D and pulmonary host defense

Surfactant protein-D (SP-D) participates in the innate response to inhaled microorganisms and organic antigens, and contributes to immune and inflammatory regulation within the lung. SP-D is synthesized and secreted by alveolar and bronchiolar epithelial cells, but is also expressed by epithelial cells lining various exocrine ducts and the mucosa of the gastrointestinal and genitourinary tracts. SP-D, a collagenous calcium-dependent lectin (or collectin), binds to surface glycoconjugates expressed by a wide variety of microorganisms, and to oligosaccharides associated with the surface of various complex organic antigens. SP-D also specifically interacts with glycoconjugates and other molecules expressed on the surface of macrophages, neutrophils, and lymphocytes. In addition, SP-D binds to specific surfactant-associated lipids and can influence the organization of lipid mixtures containing phosphatidylinositol in vitro. Consistent with these diverse in vitro activities is the observation that SP-D-deficient transgenic mice show abnormal accumulations of surfactant lipids, and respond abnormally to challenge with respiratory viruses and bacterial lipopolysaccharides. The phenotype of macrophages isolated from the lungs of SP-D-deficient mice is altered, and there is circumstantial evidence that abnormal oxidant metabolism and/or increased metalloproteinase expression contributes to the development of emphysema. The expression of SP-D is increased in response to many forms of lung injury, and deficient accumulation of appropriately oligomerized SP-D might contribute to the pathogenesis of a variety of human lung diseases

An Analysis of the Safety Performance of Air Cargo Operators

this report. Parts of this report are based on a presentation held at the 1