Sebaceous carcinoma in a mature teratoma of the ovary

The finding of a sebaceous carcinoma in a mature teratoma is rare in human pathology, with fewer than 10 cases currently reported in the literature. In this article, we report a case of sebaceous carcinoma in a mature teratoma of the ovary in a 59-year-old patient and discuss its histological findings

Epidemiological profile of ameloblastoma at Erasto Gaertner Hospital

Ameloblastoma is the most common benign tumor of odontogenic origin, and represents about 11% of all odontogenic tumors. It is characterized by being locally aggressive and having high recurrence rates. Objective: To evaluate the occurrence of ameloblastoma in the Erasto Gaertner Hospital in patients from 1972 to 2012. In addition, to assess the main treatments, the most prevalent histological variants, the recurrence rate, the anatomical location of the lesion and patient profile. Material and methods: A retrospective study of patients diagnosed with ameloblastoma at the Erasto Gaertner Hospital between the years 1972-2012 was performed. Epidemiological data were collected such as gender, age, race, lesion location, type of surgical procedure, follow-up and recurrence rate; and analyzed using descriptive statistics. Results: A total of 40 patients were selected for the study. The most affected age group was between the third and fifth decade of life, with 19 cases (47.5%), followed by the second and fourth decade, with 14 cases (35%); the sixth decade, with 5 cases (12.5%) and seventh decade with 1 case (2.5%). The patients’ ages ranged from 13 to 66 years, with an average age 34.9 years. The mandible was the most affected site, with 38 cases (95%) of cases, and maxilla had only 2 cases (5%). Thirty-eight patients were treated with radical surgery and 5 patients presented recurrence after 1 year of follow-up. Both cases that occurred in maxilla presented recurrence. Conclusion: Recurrence of ameloblastoma decreases significantly when surgery is performed properly, with wide excision and margin. Combination of full tumor resection and reconstruction was the best approach observed in this study. In addition, we recommend a long period of clinical and radiographic follow-up

Painel de Gestão Orçamentária dos Custos Assistenciais de uma Operadora de Plano de Saúde / Budgetary Management Panel of Assistance Costs of a Health Plan Operator

Este trabalho apresenta a construção de um painel com resultados orçados versus realizados, da quantidade de beneficiários, valores de receitas e custos assistenciais, utilizando-se dos conceitos de projeções, séries temporais utilizando aprendizagem de máquina supervisionada. O principal objetivo desse trabalho é apresentar a concepção de um painel de acompanhamento orçamentário, uma ferramenta para compartilhar e integrar informações entre os setores da empresa, apoiando as análises e tomada de decisões, em relação ao posicionamento de mercado, situação financeira e utilização dos recursos, referenciados por premissas de mercado, saúde e indicadores assistenciais

Effects of aging on abdominal wall healing in rats

PURPOSE: The aim of this study was to assess abdominal wall healing in old and young adult rats. METHODS: On average, young animals were 110 days old and old animals were 762 days old. A 4.0 cm median laparotomy was performed under anesthesia, followed by laparorrhaphy on two synthesis planes, i.e. peritoneum-muscle-aponeurosis and skin, using continuous 5.0 nylon sutures. The animals were evaluated on the 3rd, 7th, 14th and 21st postoperative days. The resistance of the two planes was studied separately and a histopathologic analysis was performed on sections stained with hematoxylin-eosin and Sirius Red. Immunohistochemical analysis was also carried out using PCNA, LCA and CD34. RESULTS: The skin scars gained resistance in a similar manner at the initial time points, but those of young rats were more resistant on the 21st day (p=0.0029). Total and type III collagen content was similar in the two groups and type I collagen content was higher in young animals on the 14th day. Inflammatory cell infiltration was more marked in the skin wounds of young animals on the 3rd day (p=0.0190). Reepithelialization was similar and angiogenesis was more intense in the skin wounds of young animals on the 14th day (p=0.0062). The peritoneum-muscle-aponeurosis wounds gained similar resistance during the early phases, but were more resistant on the 14th day (p=0.0005) and on the 21st day (p=0.0023) in old rats Collagen concentration was higher in the wounds of old animals on the 3rd day (p=0.0112) and in the wounds of young animals on the 21st day (p=0.0348). The inflammatory reaction was more intense in the wounds of old animals on the 3rd day (p=0.0060) and angiogenesis was more intense on the 14th day (0.0432). CONCLUSION: Although there are some differences in the healing course between young and old animals, age, of itself, does not impair the healing of abdominal wall wounds in rats

Accuracy, sensitivity and specificity of fine needle aspiration biopsy in salivary gland tumours : a retrospective study

Objective: The aim of this study was to evaluate the diagnostic accuracy, sensitivity and specificity of fine needle aspiration biopsies (FNAB) of salivary gland tumours performed at the Erasto Gaertner Hospital over the course of a four year period. Study design: A retrospective study was carried out between 2001-2005 to review the cases of patients with salivary gland tumours who had undergone pre-operative FNAB and had been diagnosed during post-operative histopathology examination. Results: A total of 106 cases of salivary gland tumours were considered for this study, but 27 cases (25.5%) of the samples were considered unsatisfactory for analysis. The sensitivity, specificity and accuracy were calculated considering only the 79 benign and malignant cases in which FNAB provided sufficient samples for analysis. Based on these data, the value of sensitivity was 68.2% (15/22), specificity was 87.7% (50/57), accuracy was 82.3% (65/79), positive predictive value was 68.2% (15/22) and negative predictive value was 87.7% (50/57). Conclusions: Despite the high rate of inadequate samples obtained in the FNAB in this study, the technique offers high specificity, accuracy and acceptable sensitivity

Perfil das infecções do trato urinário nos Campos Gerais, uma revisão da literatura / Profile of urinary tract infections in the Campos Gerais, a literature review

A infecção do trato urinário (ITU) é uma entidade nosológica  de extrema importância clínica, devido ao grande número de pacientes acometidos e às suas consequências que acarretam em morbidade e geram gastos para a saúde pública. O objetivo desta revisão é trazer alguns aspectos a respeito das terapias utilizadas em pacientes com ITU, principalmente dos estudos realizados na cidade de Ponta Grossa – Paraná, caracterizando os diferentes tipos de ITU para que possamos identificar que este tipo de infecção é bastante presente no dia a dia dos profissionais de saúde, e que é muito importante traçar o perfil de cada região para que o tratamento seja realizado de maneira correta

Sebaceous carcinoma in a mature teratoma of the ovary

The finding of a sebaceous carcinoma in a mature teratoma is rare in human pathology, with fewer than 10 cases currently reported in the literature. In this article, we report a case of sebaceous carcinoma in a mature teratoma of the ovary in a 59-year-old patient and discuss its histological findings

ABDOME AGUDO OCLUSIVO POR HEMATOMA DE INTESTINO DELGADO: RELATO DE CASO

OBJETIVO: Relatar o caso de uma paciente adulta com abdome agudo oclusivo causado por hematoma de intestino delgado.MÉTODO: Apresenta-se o caso de uma paciente atendido no serviço de urgência e emergência do HC-UFPR.RESULTADO: Paciente feminina, de 20 anos, apresentou dor no mesogástrio, distensão abdominal e vomitos. A tomografia abdominal evidenciou segmento de intestino delgado com espessamento da parede  Foi submetida a laparotomia mediana onde se evidenciou um hematoma de intestino delgado em íleo há 40 cm da valvula ileocecal, causando obstrução. Realizou-se entrerectomia segmentar de 15cm e enteroenteroanastomose. O exame anatomopatológico evidenciou hematoma extenso de submucosa do segmento ressecado.CONCLUSÃO: Os casos de abdome agudo oclusivo por hematoma de intestino delgado expontâneo são raros e devem ser manejados com tratamento clínico. Indica-se a cirurgia apenas na falha deste ou em casos de complicações durante o tratamento clinico