A mass stranding of squid Martialia hyadesi Rochebrunne & Mabille (Teuthoidea: Ommastrepidae) at Macquarie Island

A large number of squid, subsequently identified as Martialia hyadesi (Ommastrephidae) was stranded on beaches at the northern end of Macquarie Island, 54°30'S, 158°57'E, on 5 March 1971. The squid were immature, or at least pre-breeding, and had been feeding recently. It is suggested that a sudden change in wind direction, coupled with a rising tide, caused the stranding. This is the first reported stranding of this species, which has not previously been recorded in the Pacific region

Excitation thresholds of field-aligned irregularities and associated ionospheric hysteresis at very high latitudes observed using SPEAR-induced HF radar backscatter

On 10 October 2006 the SPEAR high power radar facility was operated in a power-stepping mode where both CUTLASS radars were detecting backscatter from the SPEAR-induced field-aligned irregularities (FAIs). The effective radiated power of SPEAR was varied from 1–10 MW. The aim of the experiment was to investigate the power thresholds for excitation (<I>P<sub>t</sub></I>) and collapse (<I>P<sub>c</sub></I>) of artificially-induced FAIs in the ionosphere over Svalbard. It was demonstrated that FAI could be excited by a SPEAR ERP of only 1 MW, representing only 1/30th of SPEAR's total capability, and that once created the irregularities could be maintained for even lower powers. The experiment also demonstrated that the very high latitude ionosphere exhibits hysteresis, where the down-going part of the power cycle provided a higher density of irregularities than for the equivalent part of the up-going cycle. Although this second result is similar to that observed previously by CUTLASS in conjunction with the Tromsø heater, the same is not true for the equivalent incoherent scatter measurements. The EISCAT Svalbard Radar (ESR) failed to detect any hysteresis in the plasma parameters over Svalbard in stark contract with the measurements made using the Tromsø UHF

Boundary completion is automatic and dissociable from shape discrimination

Normal visual perception readily overcomes suboptimal or degraded viewing conditions through perceptual filling-in processes, enhancing object recognition and discrimination abilities. This study used visual evoked potential (VEP) recordings in conjunction with electrical neuroimaging analyses to determine the spatiotemporal brain dynamics of boundary completion and shape discrimination processes in healthy humans performing the so-called "thin/fat" discrimination task (Ringach and Shapley, 1996) with stimuli producing illusory contours. First, results suggest that boundary completion processes occur independent of subjects' accuracy on the discrimination task. Modulation of the VEP to the presence versus absence of illusory contours [the IC effect (Murray et al., 2002)] was indistinguishable in terms of response magnitude and scalp topography over the 124-186 ms poststimulus period, regardless of whether task performance was correct. This suggests that failure on this discrimination task is not primarily a consequence of failed boundary completion. Second, the electrophysiological correlates of thin/fat shape discrimination processes are temporally dissociable from those of boundary completion, occurring during a substantially later phase of processing (approximately 330-406 ms). The earlier IC effect was unaffected by whether the perceived contour produced a thin or fat shape. In contrast, later time periods of the VEP modulated according to perceived shape only in the case of stimuli producing illusory contours, but not for control stimuli for which performance was at near-chance levels. Collectively, these data provide further support for a multistage model of object processing under degraded viewing conditions

No tumor-specific expression levels of protein kinase C isoenzymes and of c-fos in human breast cancer cell cultures

Epithelial cells derived from 46 human breast tissue samples of patients suffering from breast cancer have been cultivated. Twenty-five of these cell cultures stemmed from normal and 21 from tumor tissues. Moderate to large variations of protein levels of three protein kinase C (PKC) isoenzymes (α, Δ and ε) were found among the various cell cultures. The cell cultures also exhibited very heterogeneous basal as well as inducible levels of c-fos mRNA. However, none of these variations could be correlated with the character of the original tissue nor with any clinical parameter of the respective patient. Our results suggest that altered levels of PKC isoenzymes or of the protooncogene c-fos per se cannot serve as an indication for a transformed behavior of the epithelial cell fraction of human breast tissu

Demonstration of Calreticulin Expression in Hamster Pancreatic Adenocarcinoma with the Use of Fluorescent Gold Quantum Dots

BACKGROUND: There is dire need for discovery of novel pancreatic cancer biomarkers and of agents with the potential for simultaneous diagnostic and therapeutic capacity. This study demonstrates calreticulin expression on hamster pancreatic adenocarcinoma via bio-conjugated gold quantum dots (AuQDs). MATERIALS AND METHODS: Hamster pancreatic adenocarcinoma cells were cultured, fixed and incubated with fluorescent AuQDs, bio-conjugated to anti-calreticulin antibodies. Anti-calreticulin and AuQDs were produced in-house. AuQDs were manufactured to emit in the near-infrared. Cells were further characterized under confocal fluorescence. RESULTS: AuQDs were confirmed to emit in the near-infrared. AuQD bio-conjugation to calreticulin was confirmed via dot-blotting. Upon laser excitation and post-incubation with bio-conjugated AuQDs, pancreatic cancer cell lines emitted fluorescence in near-infrared. CONCLUSION: Hamster pancreatic cancer cells express calreticulin, which may be labelled with AuQDs. This study demonstrates the application of nanoparticle-based theranostics in pancreatic cancer. Such biomarker-targeting nanosystems are anticipated to play a significant role in the management of pancreatic cancer

Coronal and heliospheric magnetic flux circulation and its relation to open solar flux evolution

Solar cycle 24 is notable for three features that can be found in previous cycles but which have been unusually prominent: (1) sunspot activity was considerably greater in the northern/southern hemisphere during the rising/declining phase; (2) accumulation of Open Solar Flux (OSF) during the rising phase was modest, but rapid in the early declining phase; (3) the Heliospheric Current Sheet (HCS) tilt showed large fluctuations. We show these features had a major influence on the progression of the cycle. All flux emergence causes a rise then a fall in OSF, but only OSF with footpoints in opposing hemispheres progresses the solar cycle via the evolution of the polar fields. Emergence in one hemisphere, or symmetric emergence without some form of footpoint exchange across the heliographic equator, causes poleward-migrating fields of both polarities in one or both (respectively) hemispheres which temporarily enhance OSF but do not advance the polar field cycle. The heliospheric field observed near Mercury and Earth reflects the asymmetries in emergence. Using magnetograms, we find evidence that the poleward magnetic flux transport (of both polarities) is modulated by the HCS tilt, revealing an effect on OSF loss rate. The declining phase rise in OSF was caused by strong emergence in the southern hemisphere with an anomalously low HCS tilt. This implies the recent fall in the southern polar field will be sustained and that the peak OSF has limited implications for the polar field at the next sunspot minimum and hence for the amplitude of cycle 25

Brood patch and sex-ratio observations indicate breeding provenance and timing in New Zealand storm petrel (Fregetta maoriana)

We used measurements of brood patch and moult status to estimate the breeding phenology of New Zealand Storm-Petrel, using birds caught at sea within the Hauraki Gulf Marine Park near Auckland, New Zealand. Birds caught October–January had completely downy brood patches, whereas birds caught February–April had bare brood patches with an observed male bias in the February sex-ratio, consistent with a female pre-laying exodus typical of petrels and with the existence of an unknown colony in the region. No birds captured exhibited primary moult, which is known to occur in storm-petrels during their non-breeding season. Our data support the conclusion that the New Zealand storm-petrel breeds during January–June in northern New Zealand and that field surveys for the species on offshore islands in this region during this period are warrante

The early childhood generalized trust belief scale

The study was designed to develop and evaluate the Early Childhood Generalized Trust Belief Scale (ECGTBS) as a method of assessing 5-to-8-year-olds’ generalized trust. Two hundred and eleven (103 male and 108 female) children (mean age 6 years and 2 months at Time 1) completed the ECGTBS twice over a year. A subsample of participants completed the ECGTBS after two weeks to assess the scale’s test-retest reliability. Exploratory and confirmatory factor analyses confirmed that the ECGTBS assessed the expected three factors: reliability, emotional trust, and honesty with item-pairs loading most strongly on their corresponding factor. However, the ECGTBS demonstrated low to modest internal consistency and test-retest reliability which indicates a need for further development of this instrument. As evidence for the convergent validity of the ECGTBS, the reliability and emotional trust items were associated with the children’s trust in classmates at Time 2. Concurrent asymmetric quadratic relationships indicated the importance of midrange generalized trust. Specifically, children with very high generalized trust experienced greater loneliness and children with very low generalized trust had fewer friendships than children with midrange trust

The Need for Collaboration Between Ordnance Manufacturers and UXO Clean-up Personnel

The ability to locate unexploded ordnance remotely and accurately increases the safety and efficiency of clearance efforts. To achieve maximum effectiveness, UXO manufacturers and removal groups should coordinate resources and information to create new and practical technologies to assist in efforts to identify failure rates and prevent civilian casualties. The Lost Puppy Proposal is one example of a life-saving technology that could result from such collaboration