3,723 research outputs found
Results on CP Violation from the NA48 experiment at CERN
In this article the current status and latest results of the NA48 experiment
at CERN are given. We present in more details the analysis performed for the
Re(e'/e) measurement with the combined statistics accumulated during the 1998
and 1999 data periods. Reviewing the NA48 rare decay program, we select to
underline the new results on the branching ratio and the A_v factor for the
decay KL->pi0gg and the KL->pi+pi-e+e- CP violating decay. This article is the
contribution to the Proceedings of the Lepton-Photon Conference held in Roma,
July 23-29 2001.Comment: 13 pages, 11 figures, contribution to the Lepton-Photon 2001
Conference Proceedings -ne
Cytokine Production in the Serum and Spleen of Mice from Day 6 to 14 of Gestation: Cytokines/Placenta/ Spleen/Serum
Pregnancy, like most biologic phenomena, involves the action of cytokines. These proteins
have a short half-life and are believed to exert their effect close to their site of production,
where diagnostic tests cannot be easily performed. Here we show that the cytokine content
in the maternal serum reflects cytokine production and secretion from maternal spleen
cells, which also correlates with production from decidual cells. We show that GM-CSF, IL-
3, and IL-10 are present in the serum at specific time intervals during the first half of murine
pregnancy, which correlates with their production from maternal spleen cells. Purified
GM-CSF and IL-3 from spleen-cell-culture supernatants are biologically active molecules,
able to stimulate placental-cell proliferation. Furthermore, TNF-0, which has been identified
in many cases of fetal rejection as well as in labor, is shown to be naturally produced
during the second half of pregnancy. Additionally, within the limits of the sensitivity of the
technique we have used, the detection of IL-4 and the absence of detectable levels of IL-
2 in the maternal serum strongly comforts the hypothesis that pregnancy is a Th2-dependent
phenomenon. The results presented in this paper show that the cytokine profile during
pregnancy can be monitored by simple blood tests, which may be of relevance both in the
followup of a physiological human pregnancy and to the diagnosis of recurrent abortions
due to cytokine imbalance
cuticleDB: a relational database of Arthropod cuticular proteins
BACKGROUND: The insect exoskeleton or cuticle is a bi-partite composite of proteins and chitin that provides protective, skeletal and structural functions. Little information is available about the molecular structure of this important complex that exhibits a helicoidal architecture. Scores of sequences of cuticular proteins have been obtained from direct protein sequencing, from cDNAs, and from genomic analyses. Most of these cuticular protein sequences contain motifs found only in arthropod proteins. DESCRIPTION: cuticleDB is a relational database containing all structural proteins of Arthropod cuticle identified to date. Many come from direct sequencing of proteins isolated from cuticle and from sequences from cDNAs that share common features with these authentic cuticular proteins. It also includes proteins from the Drosophila melanogaster and the Anopheles gambiae genomes, that have been predicted to be cuticular proteins, based on a Pfam motif (PF00379) responsible for chitin binding in Arthropod cuticle. The total number of the database entries is 445: 370 derive from insects, 60 from Crustacea and 15 from Chelicerata. The database can be accessed from our web server at . CONCLUSIONS: CuticleDB was primarily designed to contain correct and full annotation of cuticular protein data. The database will be of help to future genome annotators. Users will be able to test hypotheses for the existence of known and also of yet unknown motifs in cuticular proteins. An analysis of motifs may contribute to understanding how proteins contribute to the physical properties of cuticle as well as to the precise nature of their interaction with chitin
Determination of the branching ratios and
Improved branching ratios were measured for the decay in a
neutral beam at the CERN SPS with the NA31 detector: and .
From the first number an upper limit for and transitions in neutral kaon decay is derived. Using older results for the
Ke3/K3 fraction, the 3 branching ratio is found to be , about a factor three more
precise than from previous experiments
Energy Linearity and Resolution of the ATLAS Electromagnetic Barrel Calorimeter in an Electron Test-Beam
A module of the ATLAS electromagnetic barrel liquid argon calorimeter was
exposed to the CERN electron test-beam at the H8 beam line upgraded for
precision momentum measurement. The available energies of the electron beam
ranged from 10 to 245 GeV. The electron beam impinged at one point
corresponding to a pseudo-rapidity of eta=0.687 and an azimuthal angle of
phi=0.28 in the ATLAS coordinate system. A detailed study of several effects
biasing the electron energy measurement allowed an energy reconstruction
procedure to be developed that ensures a good linearity and a good resolution.
Use is made of detailed Monte Carlo simulations based on Geant which describe
the longitudinal and transverse shower profiles as well as the energy
distributions. For electron energies between 15 GeV and 180 GeV the deviation
of the measured incident electron energy over the beam energy is within 0.1%.
The systematic uncertainty of the measurement is about 0.1% at low energies and
negligible at high energies. The energy resolution is found to be about 10%
sqrt(E) for the sampling term and about 0.2% for the local constant term
HGCA2.0: An RNA-Seq Based Webtool for Gene Coexpression Analysis in Homo sapiens
Genes with similar expression patterns in a set of diverse samples may be considered coexpressed. Human Gene Coexpression Analysis 2.0 (HGCA2.0) is a webtool which studies the global coexpression landscape of human genes. The website is based on the hierarchical clustering of 55,431 Homo sapiens genes based on a large-scale coexpression analysis of 3500 GTEx bulk RNA-Seq samples of healthy individuals, which were selected as the best representative samples of each tissue type. HGCA2.0 presents subclades of coexpressed genes to a gene of interest, and performs various built-in gene term enrichment analyses on the coexpressed genes, including gene ontologies, biological pathways, protein families, and diseases, while also being unique in revealing enriched transcription factors driving coexpression. HGCA2.0 has been successful in identifying not only genes with ubiquitous expression patterns, but also tissue-specific genes. Benchmarking showed that HGCA2.0 belongs to the top performing coexpression webtools, as shown by STRING analysis. HGCA2.0 creates working hypotheses for the discovery of gene partners or common biological processes that can be experimentally validated. It offers a simple and intuitive website design and user interface, as well as an API endpoint
Position resolution and particle identification with the ATLAS EM calorimeter
In the years between 2000 and 2002 several pre-series and series modules of
the ATLAS EM barrel and end-cap calorimeter were exposed to electron, photon
and pion beams. The performance of the calorimeter with respect to its finely
segmented first sampling has been studied. The polar angle resolution has been
found to be in the range 50-60 mrad/sqrt(E (GeV)). The neutral pion rejection
has been measured to be about 3.5 for 90% photon selection efficiency at pT=50
GeV/c. Electron-pion separation studies have indicated that a pion fake rate of
(0.07-0.5)% can be achieved while maintaining 90% electron identification
efficiency for energies up to 40 GeV.Comment: 32 pages, 22 figures, to be published in NIM
Search for CP violation in K0 -> 3 pi0 decays
Using data taken during the year 2000 with the NA48 detector at the CERN SPS,
a search for the CP violating decay K_S -> 3 pi0 has been performed. From a fit
to the lifetime distribution of about 4.9 million reconstructed K0/K0bar -> 3
pi0 decays, the CP violating amplitude eta_000 = A(K_S -> 3 pi0)/A(K_L -> 3
pi0) has been found to be Re(eta_000) = -0.002 +- 0.011 +- 0.015 and
Im(eta_000) = -0.003 +- 0.013 +- 0.017. This corresponds to an upper limit on
the branching fraction of Br(K_S -> 3 pi0) < 7.4 x 10^-7 at 90% confidence
level. The result is used to improve knowledge of Re(epsilon) and the CPT
violating quantity Im(delta) via the Bell-Steinberger relation.Comment: 18 pages, 7 figures, submitted to Phys. Lett.
First observation of the KS->pi0 gamma gamma decay
Using the NA48 detector at the CERN SPS, 31 KS->pi0 gamma gamma candidates
with an estimated background of 13.7 +- 3.2 events have been observed. This
first observation leads to a branching ratio of BR(KS->pi0 gamma gamma) = (4.9
+- 1.6(stat) +- 0.9(syst)) x 10^-8 in agreement with Chiral Perturbation theory
predictions.Comment: 10 pages, 4 figures submitted to Phys. Lett.
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