On the factorization of a class of Wiener-Hopf kernels

This is a pre-copy-editing, author-produced PDF of an article accepted for publication in IMA Journal of Applied Mathematics following peer review. The definitive publisher-authenticated version: Abrahams, I.D. & Lawrie, J.B. (1995) “On the factorisation of a class of Wiener-Hopf kernels.” I.M.A. J. Appl. Math., 55, 35-47. is available online at: http://imamat.oxfordjournals.org/cgi/content/abstract/55/1/35.The Wiener-Hopf technique is a powerful aid for solving a wide range of problems in mathematical physics. The key step in its application is the factorization of the Wiener-Hopf kernel into the product of two functions which have different regions of analyticity. The traditional approach to obtaining these factors gives formulae which are not particularly easy to compute. In this article a novel approach is used to derive an elegant form for the product factors of a specific class of Wiener-Hopf kernels. The method utilizes the known solution to a difference equation and the main advantage of this approach is that, without recourse to the Cauchy integral, the product factors are expressed in terms of simple, finite range integrals which are easy to compute

A brief historical perspective of the Wiener-Hopf technique

It is a little over 75 years since two of the most important mathematicians of the 20th century collaborated on finding the exact solution of a particular equation with semi-infinite convolution type integral operator. The elegance and analytical sophistication of the method, now called the Wiener–Hopf technique, impress all who use it. Its applicability to almost all branches of engineering, mathematical physics and applied mathematics is borne out by the many thousands of papers published on the subject since its conception. The Wiener–Hopf technique remains an extremely important tool for modern scientists, and the areas of application continue to broaden. This special issue of the Journal of Engineering Mathematics is dedicated to the work of Wiener and Hopf, and includes a number of articles which demonstrate the relevance of the technique to a representative range of model problems

Scattering of flexural waves by a semi-infinite crack in an elastic plate carrying an electric current

Copyright @ 2011 Sage Publications LtdSmart structures are components used in engineering applications that are capable of sensing or reacting to their environment in a predictable and desired manner. In addition to carrying mechanical loads, smart structures may alleviate vibration, reduce acoustic noise, change their mechanical properties as required or monitor their own condition. With the last point in mind, this article examines the scattering of flexural waves by a semi-infinite crack in a non-ferrous thin plate that is subjected to a constant current aligned in the direction of the crack edge. The aim is to investigate whether the current can be used to detect or inhibit the onset of crack growth. The model problem is amenable to an exact solution via the Wiener–Hopf technique, which enables an explicit analysis of the bending (and twisting) moment intensity factors at the crack tip, and also the diffracted field. The latter contains an edge wave component, and its amplitude is determined explicitly in terms of the current and angle of incidence of the forcing flexural wave. It is further observed that the edge wave phase speed exhibits a dual dependence on frequency and current, resulting in two distinct asymptotic behaviours

An orthogonality condition for a class of problems with high order boundary conditions: Applications in sound/structure interaction

This is a pre-copy-editing, author-produced PDF of an article accepted for publication in The Quarterly Journal of Mechanics and Applied Mathematics following peer review. The definitive publisher-authenticated version: Lawrie, J.B. & Abrahams, I.D. (1999) “An orthogonality condition for a class of problems with high order boundary conditions; applications in sound/structure interaction.” Q. Jl. Mech. Appl. Math., 52(2), 161-181. is available online at: http://qjmam.oxfordjournals.org/cgi/content/abstract/52/2/161There are numerous interesting physical problems, in the fields of elasticity, acoustics and electromagnetism etc., involving the propagation of waves in ducts or pipes. Often the problems consist of pipes or ducts with abrupt changes of material properties or geometry. For example, in car silencer design, where there is a sudden change in cross-sectional area, or when the bounding wall is lagged. As the wavenumber spectrum in such problems is usually discrete, the wave-field is representable by a superposition of travelling or evanescent wave modes in each region of constant duct properties. The solution to the reflection or transmission of waves in ducts is therefore most frequently obtained by mode-matching across the interface at the discontinuities in duct properties. This is easy to do if the eigenfunctions in each region form a complete orthogonal set of basis functions; therefore, orthogonality relations allow the eigenfunction coefficients to be determined by solving a simple system of linear algebraic equations. The objective of this paper is to examine a class of problems in which the boundary conditions at the duct walls are not of Dirichlet, Neumann or of impedance type, but involve second or higher derivatives of the dependent variable. Such wall conditions are found in models of fluid/structural interaction, for example membrane or plate boundaries, and in electromagnetic wave propagation. In these models the eigenfunctions are not orthogonal, and also extra edge conditions, imposed at the points of discontinuity, must be included when mode matching. This article presents a new orthogonality relation, involving eigenfunctions and their derivatives, for the general class of problems involving a scalar wave equation and high-order boundary conditions. It also discusses the procedure for incorporating the necessary edge conditions. Via two specific examples from structural acoustics, both of which have exact solutions obtainable by other techniques, it is shown that the orthogonality relation allows mode matching to follow through in the same manner as for simpler boundary conditions. That is, it yields coupled algebraic systems for the eigenfunction expansions which are easily solvable, and by which means more complicated cases, such as that illustrated in figure 1, are tractable

Quantum Tricritical Points in NbFe2_2

Quantum critical points (QCPs) emerge when a 2nd order phase transition is suppressed to zero temperature. In metals the quantum fluctuations at such a QCP can give rise to new phases including unconventional superconductivity. Whereas antiferromagnetic QCPs have been studied in considerable detail ferromagnetic (FM) QCPs are much harder to access. In almost all metals FM QCPs are avoided through either a change to 1st order transitions or through an intervening spin-density-wave (SDW) phase. Here, we study the prototype of the second case, NbFe$_2$. We demonstrate that the phase diagram can be modelled using a two-order-parameter theory in which the putative FM QCP is buried within a SDW phase. We establish the presence of quantum tricritical points (QTCPs) at which both the uniform and finite $q$ susceptibility diverge. The universal nature of our model suggests that such QTCPs arise naturally from the interplay between SDW and FM order and exist generally near a buried FM QCP of this type. Our results promote NbFe$_2$ as the first example of a QTCP, which has been proposed as a key concept in a range of narrow-band metals, including the prominent heavy-fermion compound YbRh$_2$Si$_2$.Comment: 21 pages including S

Quantum tricritical points in NbFe2

Quantum critical points (QCPs) emerge when a 2nd order phase transition is suppressed to zero temperature. In metals the quantum fluctuations at such a QCP can give rise to new phases including unconventional superconductivity. Whereas antiferromagnetic QCPs have been studied in considerable detail ferromagnetic (FM) QCPs are much harder to access. In almost all metals FM QCPs are avoided through either a change to 1st order transitions or through an intervening spin-density-wave (SDW) phase. Here, we study the prototype of the second case, NbFe$_2$. We demonstrate that the phase diagram can be modelled using a two-order-parameter theory in which the putative FM QCP is buried within a SDW phase. We establish the presence of quantum tricritical points (QTCPs) at which both the uniform and finite $q$ susceptibility diverge. The universal nature of our model suggests that such QTCPs arise naturally from the interplay between SDW and FM order and exist generally near a buried FM QCP of this type. Our results promote NbFe$_2$ as the first example of a QTCP, which has been proposed as a key concept in a range of narrow-band metals, including the prominent heavy-fermion compound YbRh$_2$Si$_2$

Joining S100 proteins and migration:for better or for worse, in sickness and in health

The vast diversity of S100 proteins has demonstrated a multitude of biological correlations with cell growth, cell differentiation and cell survival in numerous physiological and pathological conditions in all cells of the body. This review summarises some of the reported regulatory functions of S100 proteins (namely S100A1, S100A2, S100A4, S100A6, S100A7, S100A8/S100A9, S100A10, S100A11, S100A12, S100B and S100P) on cellular migration and invasion, established in both culture and animal model systems and the possible mechanisms that have been proposed to be responsible. These mechanisms involve intracellular events and components of the cytoskeletal organisation (actin/myosin filaments, intermediate filaments and microtubules) as well as extracellular signalling at different cell surface receptors (RAGE and integrins). Finally, we shall attempt to demonstrate how aberrant expression of the S100 proteins may lead to pathological events and human disorders and furthermore provide a rationale to possibly explain why the expression of some of the S100 proteins (mainly S100A4 and S100P) has led to conflicting results on motility, depending on the cells used. © 2013 Springer Basel

Qualitative Evidence Synthesis (QES) for Guidelines: Paper 2 – Using qualitative evidence synthesis findings to inform evidence-to-decision frameworks and recommendations

Background: WHO has recognised the need to improve its guideline methodology to ensure that guideline decision-making processes are transparent and evidence based, and that the resulting recommendations are relevant and applicable. To help achieve this, WHO guidelines now typically enhance intervention effectiveness data with evidence on a wider range of decision-making criteria, including how stakeholders value different outcomes, equity, gender and human rights impacts, and the acceptability and feasibility of interventions. Qualitative evidence syntheses (QES) are increasingly used to provide evidence on this wider range of issues. In this paper, we describe and discuss how to use the findings from QES to populate decision-making criteria in evidence-to-decision (EtD) frameworks. This is the second in a series of three papers that examines the use of QES in developing clinical and health system guidelines. Methods: WHO convened a writing group drawn from the technical teams involved in its recent (2010–2018) guidelines employing QES. Using a pragmatic and iterative approach that included feedback from WHO staff and other stakeholders, the group reflected on, discussed and identified key methods and research implications from designing QES and using the resulting findings in guideline development. Results: We describe a step-wise approach to populating EtD frameworks with QES findings. This involves allocating findings to the different EtD criteria (how stakeholders value different outcomes, equity, acceptability and feasibility, etc.), weaving the findings into a short narrative relevant to each criterion, and inserting this summary narrative into the corresponding ‘research evidence’ sections of the EtD. We also identify areas for further methodological research, including how best to summarise and present qualitative data to groups developing guidelines, how these groups draw on different types of evidence in their decisions, and the extent to which our experiences are relevant to decision-making processes in fields other than health. Conclusions: This paper shows the value of incorporating QES within a guideline development process, and the roles that qualitative evidence can play in integrating the views and experiences of relevant stakeholders, including groups who may not be otherwise represented in the decision-making process