Improving Link Reliability through Network Coding in Cooperative Cellular Networks

The paper proposes a XOR-based network coded cooperation protocol for the uplink transmission of relay assisted cellular networks and an algorithm for selection and assignment of the relay nodes. The performances of the cooperation protocol are expressed in terms of network decoder outage probability and Block Error Rate of the cooperating users. These performance indicators are analyzed theoretically and by computer simulations. The relay nodes assignment is based on the optimization, according to several criteria, of the graph that describes the cooperation cluster formed after an initial selection of the relay nodes. The graph optimization is performed using Genetic Algorithms adapted to the topology of the cooperation cluster and the optimization criteria considered

'Gewoon worden wie je bent': Over authenticiteit en anti-institutionalisme

Analysis of a dozen semi-structured interviews with Dutch New Age trainers demonstrates that the modern 'ethics of authenticity' underlies contemporary society's anti-institutional mood. All institutions, be they traditional or modern, or so our respondants argue, prevent one from being true to oneself. Institutional pressure for conformity to social roles, they maintain, causes feelings of alienation, mental and physical illness, malicious types of sexuality, violence and many other problems. Although the ethics of authenticity thus produces a demonization of institutions, it simultaneously, and in quite a paradoxical way, exerts considerable institutional pressure itself. Politicians, media stars and others are today morally expected to be authentic: to be true to themselves and express their emotions in public

Combining learning and optimization for transprecision computing

The growing demands of the worldwide IT infrastructure stress the need for reduced power consumption, which is addressed in so-called transprecision computing by improving energy efficiency at the expense of precision. For example, reducing the number of bits for some floating-point operations leads to higher efficiency, but also to a non-linear decrease of the computation accuracy. Depending on the application, small errors can be tolerated, thus allowing to fine-tune the precision of the computation. Finding the optimal precision for all variables in respect of an error bound is a complex task, which is tackled in the literature via heuristics. In this paper, we report on a first attempt to address the problem by combining a Mathematical Programming (MP) model and a Machine Learning (ML) model, following the Empirical Model Learning methodology. The ML model learns the relation between variables precision and the output error; this information is then embedded in the MP focused on minimizing the number of bits. An additional refinement phase is then added to improve the quality of the solution. The experimental results demonstrate an average speedup of 6.5% and a 3% increase in solution quality compared to the state-of-the-art. In addition, experiments on a hardware platform capable of mixed-precision arithmetic (PULPissimo) show the benefits of the proposed approach, with energy savings of around 40% compared to fixed-precision

Disruption of the basal body protein POC1B results in autosomal-recessive cone-rod dystrophy

Exome sequencing revealed a homozygous missense mutation (c.317C>G [p.Arg106Pro]) in POC1B, encoding POC1 centriolar protein B, in three siblings with autosomal-recessive cone dystrophy or cone-rod dystrophy and compound-heterozygous POC1B mutations (c.199_201del [p.G1n67del] and c.810+1G>T) in an unrelated person with cone-rod dystrophy. Upon overexpression of POC1B in human TERT-immortalized retinal pigment epithelium 1 cells, the encoded wild-type protein localized to the basal body of the primary cilium, whereas this localization was lost for p.Arg106Pro and p.G1n67del variant forms of POC1B. Morpholino-oligonucleotide-induced knockdown of poc1b translation in zebrafish resulted in a dose-dependent small-eye phenotype, impaired optokinetic responses, and decreased length of photoreceptor outer segments. These ocular phenotypes could partially be rescued by wild-type human POC1B mRNA, but not by c.199_201del and c.317C>G mutant human POC1B mRNAs. Yeast two-hybrid screening of a human retinal cDNA library revealed FAM161A as a binary interaction partner of POC1B. This was confirmed in coimmunoprecipitation and colocalization assays, which both showed loss of FAM161A interaction with p.Arg106Pro and p.G1n67del variant forms of POC1B. FAM161A was previously implicated in autosomal-recessive retinitis pigmentosa and shown to be located at the base of the photoreceptor connecting cilium, where it interacts with several other ciliopathy-associated proteins. Altogether, this study demonstrates that POC1B mutations result in a defect of the photoreceptor sensory cilium and thus affect cone and rod photoreceptors

Investigating commercially relevant packaging solutions to improve storage stability of mechanically filleted Atlantic mackerel (Scomber scombrus) produced under industrial conditions

This study investigated the efficacy of three commercially relevant packaging methods (vacuum with water glazing VAC-G; vacuum with seawater VAC-S; shatter-layer packaging SL) to improve frozen storage stability of mechanically filleted Atlantic mackerel at −\ua025\ua0\ub0C, in comparison to water glazing alone (GL) and storage as whole unglazed, block frozen fish. Besides proximate composition and pH of raw material, quality changes were analysed by free fatty acid content (FFA), water holding capacity (WHC), cooking yield, lipid oxidation (lipid hydroperoxides, PV; non-protein bound thiobarbituric acid reactive substances, TBARS) and sensory profiles of cooked samples after 3.5, 8, 10 and 12\ua0months of frozen storage. Vacuum-packaging was effective in mitigating the PV and TBARS as well as rancid odour and flavour. The inclusion of seawater in VAC-S altered the sensory textural attributes of the mackerel fillet to be more juicy, tender and soft and increased the attribute of salty flavour in the sample. SL delayed rancid odour and flavour by 2\ua0months compared to GL. Processing of mackerel under industrial conditions, including filleting, handling, double-freezing and glazing accelerated the formation of FFA as well as losses of WHC and cooking yield in the fillet regardless the packaging methods