Le mal de pott sous occipital révélé par un abcès rétro pharyngien a propos d’un cas

Introduction : Pott's disease is the most frequent localisation of osteo-articular tuberculosis. The suboccipital localisation remains rare. Case report : A 12-years old boy, admitted for cervicalgy and dysphagia. His clinical exam revealed a swelling of posterior pharyngeal wall associated with a basicervical tumefaction fistulased to the skin. Cervical spine MRI and cervico-thoracic tomodensitometry show a retro-pharyngeal collection associated with necrosed mediastinal adenopathies and apical pulmonar retractile lesion. The patient underwent, in emergency, an incision of the retro-pharyngeal abscess. The biological assessment revealed an inflommatory syndrom. A tuberculine intra dermo-reaction was negative whereas the BK research were positive. The diagnosis of suboccipital Pott's disease associated with pulmonar tuberculosis was done. The anti-tuberculosis drug was mentained for 11 months with a good recovery. The follow-up was 6 years. Discussion : The sub occipital pain Pott localisation was rare. The cervicalgy was the important clinical sign of consultation. Whearas, the dysphagia and retro-pharyngeal abscess could be revealing. The MRI was necessary for an early diagnosis. The diagnosis confirmation was made by the presence of Mycobacterium Koch in the pottic lesion. The treatment was based on the anti-tuberculosis drugs for a period of 11 months completed with an orthopedic or surgical stabilisation of cervical occipital jonction.Keywords : Pott’s disease, tuberculosis, cervical spine, MRI, Mycobacterium Koch

Localisation rare du melanome muqueux

Purpose: Mucosal melanoma of the upper respiratory tract is rare. Nasopharyngeal involvement is extremely rare. The diagnosis and management of this tumour still remain difficult. We present a new case of mucosal nasopharyngeal melanoma, to discuss diagnosis and therapeutic modalities.Observation: A 15-year-old girl was referred to the department of otolaryngology because of bilateral cervical mass with bilateral nasal obstruction, right otalgia and chronic headache. Nasopharyngeal tumour was observed endoscopically. The histologic examination showed mucosal melanoma. No distant metastatic localisations were identified. The patientunderwent cervical lymph node dissection followed by 6 courses of chemotherapy, but she died 9 months later because of loco-regional failures.Conclusion: The primary malignant melanoma of nasopharyngeal is extremely rare disease particularly among child. Its histologic diagnosis is challenging. The treatment still remains controversial. The prognosis is poor because of anatomic localisation and high frequency of distant metastasis.Key words: Melanoma, nasopharynx, immuno-histochemistry

Complications orbitaires de la polypose nasosinusienne de l’enfant

La polypose nasosinusienne (PNS) est une pathologie rare chez l’enfant. La symptomatologie clinique est habituellement celle de l’adulte. Exceptionnellement, une complication locorégionale lui est révélatrice. A travers deux observations de PNS diagnostiquées suite à une complication orbitaire, on discute les particularités cliniques de cette entité ainsi que ses implications thérapeutiques. Il s’agissait de deux enfants âgés de 13 ans ayant été hospitalisés pour une exophtalmie unilatérale d’apparition aiguë. L’examen clinique a découvert une PNS surinfectée évoquant alors le diagnostic de complication orbitaire d’origine infectieuse, confirmé par l’imagerie. Le traitement a associé un drainage chirurgical d’urgence de l’abcès orbitaire par voie externe paracanthale interne, suivi par une corticothérapie locale. L’ethmoïdectomie a été nécessaire dans un cas. L’évolution était favorable dans les deux cas avec une stabilisation de la PNS et une absence de signes de récidive de l’infection orbitaire

Les Surdites Brusques Idiopathiques Facteurs Pronostiques

Introduction : Les surdités brusques idiopathiques (SBI) constituent l\'un des sujets les plus débattus en otologie. Plusieurs problèmes d\'ordre physiopathologiques, thérapeutiques et pronostiques restent non résolus. But : Identifier les facteurs pronostiques, cliniques et audiométriques de récupération auditive après traitement d\'une SBI. Malades : Etude rétrospective portée sur 27 malades (29 cas de SBI) traités dans le service d\'ORL et chirurgie cervicofaciale du CHU Habib Bourguiba Sfax durant la période comprise entre les années 1990 et 2005. Méthodes : C\'est une étude statistique recherchant une corrélation significative entre certains facteurs cliniques et audiométriques et la récupération auditive. Les facteurs étudiés étaient : l\'âge, l\'aspect de la courbe audiométrique, la perte auditive initiale et le délai de prise en charge thérapeutique. Résultats : L\'âge inférieur à 50 ans, la courbe ascendante et la perte auditive inférieure à 70 dB étaient les facteurs de meilleur pronostic. Le délai de prise en charge thérapeutique semble avoir peu de rôle dans la récupération auditive. Discussion : La majorité des auteurs ont signalé que l\'âge jeune, les surdités légères ou moyennes, la courbe ascendante et la précocité de la prise en charge sont associés à un meilleur pronostic. Nos résultats rejoignent ceux de Tran Ba Huy qui ne trouve pas de corrélation entre le délai de prise en charge thérapeutique et le pronostic de récupération auditive.Introduction : Idiopathic Sudden Sensorineural Hearing Loss (ISSHL) remains one of the major otologic debates. Many etiopathogenic, therapeutic and prognostic problems are still unsolved. Purpose : Identify some clinical and audiometric factors influencing the recovery prognostic after treatment of ISSHL. Patients : Retrospective study of 27 patients (29 cases of ISSHL) treated in the department of Oto-Rhino-Laryngology and Head and Neck Surgery of Habib Bourguiba Hospital during the period from 1990 to 2005. Method: We underwent a statistical data to search a significant correlation between some clinical, audiometric factors and hearing recovery. The factors studied are: age of patient, the type of the tonal audiogram shape, the degree of the initial hearing loss and the therapeutic delay. Results: The age under 50 years, the ascending audiogram shape and initial hearing loss under 70dB involve a better prognostic. The therapeutic delay seems have a little role in the hearing recovery. Discussion: The majority of authors concluded that the young age, the mild and moderate hearing loss, the ascending audiogram shape and the precocity of treatment are correlated to a better prognostic. We, as Tran Ba Huy, don\'t find a significant correlation between the therapeutic delay and the quality of hearing recovery. Journal Tunisien d\'ORL et de chirurgie cervico-faciale Vol. 18 2007: pp. 7-1

Kyste Dermoïde Du Plancher Buccal

Le kyste dermoïde du plancher buccal est une entité rare. Il touche essentiellement le sujet jeune. Nous rapportons l\'observation d\'un nourrisson âgé de 9 mois qui a été amené par ses parents pour fistule sous mentale sans aucune gêne fonctionnelle associée. L\'examen clinique a révélé une voussure du plancher buccal antérieur. L\'IRM a montré une lésion kystique du plancher buccal en hyposignal T1 et hypersignal T2. L\'enfant a été opéré par voie endobuccale. Les suites opératoires étaient simples. L\'examen anatomopathologique a conclu à un kyste dermoïde. Nous discutons, dans ce travail, les caractéristiques cliniques, radiologiques et les volets thérapeutiques de cette entité. Keywords: kyste dermoïde, plancher buccal. Journal Tunisien d\'ORL et de chirurgie cervico-faciale Vol. 18 2007: pp. 58-6

Is diet partly responsible for differences in COVID-19 death rates between and within countries?

Correction: Volume: 10 Issue: 1 Article Number: 44 DOI: 10.1186/s13601-020-00351-w Published: OCT 26 2020Reported COVID-19 deaths in Germany are relatively low as compared to many European countries. Among the several explanations proposed, an early and large testing of the population was put forward. Most current debates on COVID-19 focus on the differences among countries, but little attention has been given to regional differences and diet. The low-death rate European countries (e.g. Austria, Baltic States, Czech Republic, Finland, Norway, Poland, Slovakia) have used different quarantine and/or confinement times and methods and none have performed as many early tests as Germany. Among other factors that may be significant are the dietary habits. It seems that some foods largely used in these countries may reduce angiotensin-converting enzyme activity or are anti-oxidants. Among the many possible areas of research, it might be important to understand diet and angiotensin-converting enzyme-2 (ACE2) levels in populations with different COVID-19 death rates since dietary interventions may be of great benefit.Peer reviewe

Quantitative diffusion-weighted MRI response assessment in rhabdomyosarcoma: an international retrospective study on behalf of the European paediatric Soft tissue sarcoma Study Group Imaging Committee

Objective: To investigate the feasibility of diffusion-weighted magnetic resonance imaging (DW-MRI) as a predictive imaging marker after neoadjuvant chemotherapy in patients with rhabdomyosarcoma. Material and methods: We performed a multicenter retrospective study including pediatric, adolescent and young adult patients with rhabdomyosarcoma, Intergroup Rhabdomyosarcoma Study group III/IV, treated according to the European paediatric Soft tissue sarcoma Study Group (EpSSG) RMS2005 or MTS2008 studies. DW-MRI was performed according to institutional protocols. We performed two-dimensional single-slice tumor delineation. Areas of necrosis or hemorrhage were delineated to be excluded in the primary analysis. Mean, median and 5th and 95th apparent diffusion coefficient (ADC) were extracted. Results: Of 134 included patients, 82 had measurable tumor at diagnosis and response and DW-MRI scans of adequate quality and were included in the analysis. Technical heterogeneity in scan acquisition protocols and scanners was observed. Mean ADC at diagnosis was 1.1 (95% confidence interval [CI]: 1.1–1.2) (all ADC expressed in * 10−3 mm2/s), versus 1.6 (1.5–1.6) at response assessment. The 5th percentile ADC was 0.8 (0.7–0.9) at diagnosis and 1.1 (1.0–1.2) at response. Absolute change in mean ADC after neoadjuvant chemotherapy was 0.4 (0.3–0.5). Exploratory analyses for association between ADC and clinical parameters showed a significant difference in mean ADC at diagnosis for alveolar versus embryonal histology. Landmark analysis at nine weeks after the date of diagnosis showed no significant association (hazard ratio 1.3 [0.6–3.2]) between the mean ADC change and event-free survival. Conclusion: A significant change in the 5th percentile and the mean ADC after chemotherapy was observed. Strong heterogeneity was identified in DW-MRI acquisition protocols between centers and in individual patients. Graphical Abstract: [Figure not available: see fulltext.

Valeur de L\'examen extemporane dans la chirurgie des nodules thyroidiens

No Abstract. Journal Tunisien d\'ORL et de chirurgie cervico-faciale Vol. 17 2006: pp. 13-1