394 research outputs found

    CCAFS Gender and Social Inclusion Strategy

    Get PDF
    The CCAFS Gender and Social Inclusion (GSI) Strategy is an update of the CCAFS 2012 Gender Strategy. The new strategy addresses gender as well as social inclusion for different social groups while bearing in mind that women are central to agriculture in developing countries. The CCAFS approach to GSI allies with the CGIAR objectives to create opportunities for women, young people and marginalized groups and to promote equitable access to resources, information and power in the agri-food system for men and women in order to close the gender gap by 2030

    Supporting women farmers in a changing climate: five policy lessons

    Get PDF
    Policies, institutions and services to help farmers develop new approaches to deal with climate change will need to produce results for women farmers as well as men. This brief provides five policy lessons to support this process, based on evidence from research in low- and middle- income countries and offers guidelines for crafting gender-responsive climate policies at global and national levels. This research was presented in March 2015 at a seminar in Paris on ‘Closing the gender gap in farming under climate change’, co-organized by the CGIAR Research Program on Climate Change, Agriculture and Food Security (CCAFS), the International Social Science Council (ISSC) and Future Earth

    Apoyo a las mujeres agricultoras en un clima cambiante: cinco lecciones de políticas

    Get PDF
    Recientes investigaciones presentadas en un seminario en París, coorganizado por el Programa de Investigación de CGIAR en Cambio Climático, Agricultura y Seguridad Alimentaria (CCAFS), el Consejo Internacional de Ciencias Sociales (CICS) y Future Earth, dieron lugar a cinco recomendaciones de políticas clave para apoyar a las mujeres agricultoras en un clima cambiante. Los conocimientos y competencias técnicas únicos de las mujeres en materia de gestión ambiental pueden contribuir a hallar soluciones innovadoras que hagan frente a los problemas causados por el cambio climático. English version: https://cgspace.cgiar.org/bitstream/handle/10568/68533/CCAFS%20PB10.pdf?sequence=

    Aider les femmes agricultrices à vivre le changement climatique: cinq recommandations politique

    Get PDF
    Une recherche récente présentée lors d’une conférence à Paris co-organisée par le programme de recherche du CGIAR sur le changement climatique, l’agriculture et la sécurité alimentaire (CCAFS), le Conseil international des sciences sociales (CISS) et Future Earth a produit cinq recommandations politiques essentielles pour aider les femmes agricultrices à vivre le changement climatique. L’expertise unique des femmes concernant la gestion environnementale peut contribuer au développement des solutions innovantes pour répondre à l’urgence climatique. English version: https://cgspace.cgiar.org/bitstream/handle/10568/68533/CCAFS%20PB10.pdf?sequence=

    Climate change, policy change: Five policy lessons to support women farmers in a changing climate

    Get PDF
    Climate change demands new approaches to agriculture: farmers’ practices will need to change to adapt to and mitigate the effects of changing conditions. Addressing gender inequality is key to ensuring this outcome. Agriculture is a fundamental part of women’s livelihoods globally, most markedly in least developed countries, where four-fifths of economically active women report agriculture as their primary economic activity1 . More women are moving into agriculture as men move elsewhere for seasonal or paid labor. Yet women farmers have less access to inputs and resources that could improve their farming and meet climate change challenges2 . Policies, institutions and services aimed at helping farmers develop approaches to tackle climate change will need to produce results for men and women farmers. This brief provides five policy lessons to support this process, based on evidence from research in low- and middle-income countries

    Estrogen inhibits GH signaling by suppressing GH-induced JAK2 phosphorylation, an effect mediated by SOCS-2

    Get PDF
    Oral estrogen administration attenuates the metabolic action of growth hormone (GH) in humans. To investigate the mechanism involved, we studied the effects of estrogen on GH signaling through Janus kinase (JAK)2 and the signal transducers and activators of transcription (STATs) in HEK293 cells stably expressing the GH receptor (293GHR), HuH7 (hepatoma) and T-47D (breast cancer) cells. 293GHR cells were transiently transfected with an estrogen receptor-α expression plasmid and luciferase reporters with binding elements for STAT3 and STAT5 or the β-casein promoter. GH stimulated the reporter activities by four- to sixfold. Cotreatment with 17β-estradiol (E2) resulted in a dose-dependent reduction in the response of all three reporters to GH to a maximum of 49-66% of control at 100 nM (P < 0.05). No reduction was seen when E2 was added 1-2 h after GH treatment. Similar inhibitory effects were observed in HuH7 and T-47D cells. E2 suppressed GH-induced JAK2 phosphorylation, an effect attenuated by actinomycin D, suggesting a requirement for gene expression. Next, we investigated the role of the suppressors of cytokine signaling (SOCS) in E2 inhibition. E2 increased the mRNA abundance of SOCS-2 but not SOCS-1 and SOCS-3 in HEK293 cells. The inhibitory effect of E2 was absent in cells lacking SOCS-2 but not in those lacking SOCS-1 and SOCS-3. In conclusion, estrogen inhibits GH signaling, an action mediated by SOCS-2. This paper provides evidence for regulatory interaction between a sex steroid and the GH/JAK/STAT pathway, in which SOCS-2 plays a central mechanistic role
    • …
    corecore