Decoupling of internal and external workload during a marathon: An analysis of durability in 82,303 recreational runner

© 2022 The Author(s). This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY), https://creativecommons.org/licenses/by/4.0/Aim: This study characterised the decoupling of internal-to-external workload in marathon running and investigated whether decoupling magnitude and onset could improve predictions of marathon performance. Methods: The decoupling of internal-to-external workload was calculated in 82,303 marathon runners (13,125 female). Internal workload was determined as a percentage of maximum heart rate, and external workload as speed relative to estimated critical speed (CS). Decoupling magnitude (i.e., decoupling in the 35–40 km segment relative to the 5–10 km segment) was classified as low (< 1.1), moderate (≥ 1.1 but < 1.2) or high (≥ 1.2). Decoupling onset was calculated when decoupling exceeded 1.025. Results: The overall internal-to-external workload decoupling experienced was 1.16 ± 0.22, first detected 25.2 ± 9.9 km into marathon running. The low decoupling group (34.5% of runners) completed the marathon at a faster relative speed (88 ± 6% CS), had better marathon performance (217.3 ± 33.1 min), and first experienced decoupling later in the marathon (33.4 ± 9.0 km) compared to those in the moderate (32.7% of runners, 86 ± 6% CS, 224.9 ± 31.7 min, and 22.6 ± 7.7 km), and high decoupling groups (32.8% runners, 82 ± 7% CS, 238.5 ± 30.7 min, and 19.1 ± 6.8 km; all p < 0.01). Compared to females, males’ decoupling magnitude was greater (1.17 ± 0.22 vs. 1.12 ± 0.16; p < 0.01) and occurred earlier (25.0 ± 9.8 vs. 26.3 ± 10.6 km; p < 0.01). Marathon performance was associated with the magnitude and onset of decoupling, and when included in marathon performance models utilising CS and the curvature constant, prediction error was reduced from 6.45 to 5.16%. Conclusion: Durability characteristics, assessed as internal-to-external workload ratio, show considerable inter-individual variability, and both its magnitude and onset are associated with marathon performance.Peer reviewe

Estimation of Connected Vehicle Penetration Rate on Indiana Roadways

Over 400 billion passenger vehicle trajectory waypoints are collected each month in the United States. This data creates many new opportunities for agencies to assess operational characteristics of roadways for more agile management of resources. This study compared traffic counts obtained from 24 Indiana Department of Transportation traffic counts stations with counts derived by the vehicle trajectories during the same periods. These stations were geographically distributed throughout Indiana with 13 locations on interstates and 11 locations on state or US roads. A Wednesday and a Saturday in January, August, and September 2020 are analyzed. The results show that the analyzed interstates had an average penetration of 4.3% with a standard deviation of 1.0. The non-interstate roads had an average penetration of 5.0% with a standard deviation of 1.36. These penetration levels suggest that connected vehicle data can provide a valuable data source for developing scalable roadway performance measures. Since all agencies currently have a highway monitoring system using fixed infrastructure, this paper concludes by recommending agencies integrate a connected vehicle penetration monitoring program into their traditional highway count station program to monitor the growing penetration of connected cars and trucks

Fluctuation-Dissipation-Theorem violation during the formation of a colloidal-glass

The relationship between the conductivity and the polarization noise is measured in a gel as a function of frequency in the range $1Hz - 40Hz$. It is found that at the beginning of the transition from a fluid like sol to a solid like gel the fluctuation dissipation theorem is strongly violated. The amplitude and the persistence time of this violation are decreasing functions of frequency. At the lowest frequencies of the measuring range it persists for times which are about 5% of the time needed to form the gel. This phenomenology is quite close to the recent theoretical predictions done for the violation of the fluctuation dissipation theorem in glassy systems.Comment: 6 pages + 4 figure

The Ursinus Weekly, October 22, 1962

Queen & football victory highlight Saturday\u27s Homecoming festivities • Students enjoy Winterthur visit • Pre-medicals hear student talks • Gould, Moser, Harris and Miller elected as freshman officers • Recent Spike convocation provocative, analytic • Tim Cope elected as MSGA soph rep. • Sororities take in 54 women • Weekly meeting for new members • Dawson and King chosen for cheerleading squad • PSEA meeting opens season • Innkeepers tour from G-B to UC • Young GOPers outline voting procedure • Ruby sales begin • Cole family concert slated for Norristown • Millers join koffee klatch opener • Editorial: A broken back • UC coed writes of Summer experiences at reform school • A report on the customs program • The Weekly interviews 3 of our 9 foreign students • Dr. Eugene Miller reports on India in recent Forum • UC downs Swarthmore 14-8 • Players of the week: Sermarini & Ritz real hustlers • Next week\u27s opponent: Wagner • Soccermen defeat East Baptist, Delaware to remain undefeated • Hockeyettes down WC & Swarthmore • Berlinger asset on soccer field • Greek gleanings • Dean\u27s listhttps://digitalcommons.ursinus.edu/weekly/1278/thumbnail.jp

Direct observations of the kinetics of migrating T-cells suggest active retention by endothelial cells with continual bidirectional migration.

The kinetics and regulatory mechanisms of T-cell migration through endothelium have not been fully defined. In experimental filter-based assays in vitro, transmigration of lymphocytes takes hours, compared to minutes in vivo. We cultured endothelial cell (EC) monolayers on filters, solid substrates or collagen gels, and treated them with tumour necrosis factor-α (TNF), interferon-γ (IFN), or both, prior to analysis of lymphocyte migration in the presence or absence of flow. Peripheral blood lymphocytes (PBL), CD4+ cells or CD8+ cells, took many hours to migrate through EC-filter constructs for all cytokine treatments. However, direct microscopic observations of EC-filters which had been mounted in a flow chamber showed that PBL crossed the endothelial monolayer in minutes and were highly motile in the subendothelial space. Migration through EC was also observed on clear plastic, with or without flow. After brief settling without flow, PBL and isolated CD3+ or CD4+ cells all crossed EC in minutes, but the numbers of migrated cells varied little with time. Close observation revealed that lymphocytes continuously migrated back and forth across endothelium. Under flow, migration kinetics and the proportions migrating back and forth were little altered. On collagen gels, PBL again crossed EC in minutes and migrated back and forth, but showed little penetration of the gel over hours.In contrast, neutrophils migrated efficiently through EC and into gels. These observations suggest a novel model for lymphoid migration, in which endothelial cells support migration but retain lymphocytes (as opposed to neutrophils), and additional signal(s) are required for onward migration

International Wildlife Law : Understanding and Enhancing Its Role in Conservation

We gratefully acknowledge valuable input by Kees Bastmeijer, Sanja Bogojevic, Jennifer Dubrulle, and Han Somsen.Peer reviewedPublisher PD

Direct Observations of the Ionizing Star in the UC HII Region G29.96-0.02: A Strong Constraint on the Stellar Birth Line for Massive Stars

We have observed the ultracompact HII region G29.96-0.02 in the near infrared J, H, and K bands and in the Br-gamma line. By comparison with radio observations, we determine that the extinction to the nebula is AK = 2.14 with a 3 sigma uncertainty of 0.25. We identify the ionizing star and determine its intrinsic K magnitude. The star does not have an infrared excess and so appears to be no longer accreting. The K magnitude and the bolometric luminosity allow us to place limits on the location of the ionizing star in the HR diagram. The 3 sigma upper limit on the effective temperature of the ionizing star is 42500 K. We favor a luminosity appropriate for star with a mass in excess of about 60 solar masses. The limit on the temperature and luminosity exclude stars on the ZAMS and stars within 10^6 yr of the ZAMS. Since the age of the UC HII region is estimated to be only about 10^5 yr, we suggest that this is direct evidence that the stellar birth line for massive stars at twice solar metallicity must be significantly redder than the ZAMS.Comment: 42 pages; LaTex; 11 Postscript figures; accepted for publication in Ap

First-order phase transition during displacement of amphiphilic biomacromolecules from interfaces by surfactant molecules

The adsorption of surfactants onto a hydrophobic interface, already laden with a fixed number of amphiphilic macromolecules, is studied using the self consistent field calculation method of Scheutjens and Fleer. For biopolymers having unfavourable interactions with the surfactant molecules, the adsorption isotherms show an abrupt jump at a certain value of surfactant bulk concentration. Alternatively, the same behaviour is exhibited when the number of amphiphilic chains on the interface is decreased. We show that this sudden jump is associated with a first-order phase transition, by calculating the free energy values for the stable and the metastable states at both sides of the transition point. We also observe that the transition can occur for two approaching surfaces, from a high surfactant coverage phase to a low surfactant coverage one, at sufficiently close separation distances. The consequence of this finding for the steric colloidal interactions, induced by the overlap of two biopolymer + surfactant films, is explored. In particular, a significantly different interaction, in terms of its magnitude and range, is predicted for these two phases. We also consider the relevance of the current study to problems involving the competitive displacement of proteins by surfactants in food colloid systems