218 research outputs found
EP-1199: The identification of putative biomarkers of radioresistance in rectal cancer tissue using antibody microarray
ALMA observations of the Extended Green Object G19.01-0.03 - I. A Keplerian disc in a massive protostellar system
Interstellar matter and star formatio
(Sub)mm Interferometry Applications in Star Formation Research
This contribution gives an overview about various applications of (sub)mm
interferometry in star formation research. The topics covered are molecular
outflows, accretion disks, fragmentation and chemical properties of low- and
high-mass star-forming regions. A short outlook on the capabilities of ALMA is
given as well.Comment: 20 pages, 7 figures, in proceedings to "2nd European School on Jets
from Young Star: High Angular Resolution Observations". A high-resolution
version of the paper can be found at
http://www.mpia.de/homes/beuther/papers.htm
Telecommunication wavelength GaAsBi light emitting diodes
GaAsBi light emitting diodes containing ∼6% Bi are grown on GaAs substrates. Good room-temperature electroluminescence spectra are obtained at current densities as low as 8 Acm − 2. Measurements of the integrated emitted luminescence suggest that there is a continuum of localised Bi states extending up to 75 meV into the bandgap, which is in good agreement with previous photoluminescence studies. X-ray diffraction analysis shows that strain relaxation has probably occurred in the thicker samples grown in this study
Investigating the effects of an oral fructose challenge on hepatic ATP reserves in healthy volunteers: a 31P MRS study
Background: Impaired homeostasis of hepatic ATP has been associated with NAFLD. An intravenous fructose infusion has been shown to be an effective challenge to monitor the depletion and subsequent recovery of hepatic ATP reserves using 31P MRS.
Aims: The purpose of this study was to evaluate the effects of an oral rather than intravenous fructose challenge on hepatic ATP reserves in healthy subjects.
Methods: Self-reported healthy males were recruited. Following an overnight fast, baseline liver glycogen and lipid levels were measured using Magnetic Resonance Spectroscopy (MRS). Immediately after consuming a 500 ml 75 g fructose drink (1275 kJ) subjects were scanned continuously for 90 min to acquire dynamic 31P MRS measurements of liver ATP reserves.
Results: A significant effect on ATP reserves was observed across the time course (P < 0.05). Mean ATP levels reached a minimum at 50 min which was markedly lower than baseline (80 ± 17% baseline, P < 0.05). Subsequently, mean values tended to rise but did not reach statistical significance above minimum. The time to minimum ATP levels across subjects was negatively correlated with BMI (R2 ¼ 0.74, P < 0.005). Rates of ATP recovery were not significantly correlated with BMI or liver fat levels, but were negatively correlated with baseline glycogen levels (R2 ¼ 0.7, P < 0.05).
Conclusions: Depletion of ATP reserves can be measured non-invasively following an oral fructose challenge using 31P
3d CFT and Multi M2-brane Theory on RxS^2
The radial quantization of N=8 theory in three dimensions is considered i.e.
we study the N=8 BLG theory on RxS^2. We present the explicit from of the
Lagrangian and the corresponding supersymmetry transformations and
supersymmetry algebra. We study spectrum of this theory and some of its BPS
configurations.Comment: 13 page
The long-term survival chances of young massive star clusters
We review the long-term survival chances of young massive star clusters
(YMCs), hallmarks of intense starburst episodes often associated with violent
galaxy interactions. We address the key question as to whether at least some of
these YMCs can be considered proto-globular clusters (GCs), in which case these
would be expected to evolve into counterparts of the ubiquitous old GCs
believed to be among the oldest galactic building blocks. In the absence of
significant external perturbations, the key factor determining a cluster's
long-term survival chances is the shape of its stellar initial mass function
(IMF). It is, however, not straightforward to assess the IMF shape in
unresolved extragalactic YMCs. We discuss in detail the promise of using
high-resolution spectroscopy to make progress towards this goal, as well as the
numerous pitfalls associated with this approach. We also discuss the latest
progress in worldwide efforts to better understand the evolution of entire
cluster systems, the disruption processes they are affected by, and whether we
can use recently gained insights to determine the nature of at least some of
the YMCs observed in extragalactic starbursts as proto-GCs. We conclude that
there is an increasing body of evidence that GC formation appears to be
continuing until today; their long-term evolution crucially depends on their
environmental conditions, however.Comment: invited refereed review article; ChJA&A, in press; 33 pages LaTeX (2
postscript figures); requires chjaa.cls style fil
FTO genetic variants, dietary intake and body mass index: insights from 177 330 individuals
FTO is the strongest known genetic susceptibility locus for obesity. Experimental studies in animals suggest the potential roles of FTO in regulating food intake. The interactive relation among FTO variants, dietary intake and body mass index (BMI) is complex and results from previous often small-scale studies in humans are highly inconsistent. We performed large-scale analyses based on data from 177 330 adults (154 439 Whites, 5776 African Americans and 17 115 Asians) from 40 studies to examine: (i) the association between the FTO-rs9939609 variant (or a proxy single-nucleotide polymorphism) and total energy and macronutrient intake and (ii) the interaction between the FTO variant and dietary intake on BMI. The minor allele (A-allele) of the FTO-rs9939609 variant was associated with higher BMI in Whites (effect per allele = 0.34 [0.31, 0.37] kg/m2, P = 1.9 × 10−105), and all participants (0.30 [0.30, 0.35] kg/m2, P = 3.6 × 10−107). The BMI-increasing allele of the FTO variant showed a significant association with higher dietary protein intake (effect per allele = 0.08 [0.06, 0.10] %, P = 2.4 × 10−16), and relative weak associations with lower total energy intake (−6.4 [−10.1, −2.6] kcal/day, P = 0.001) and lower dietary carbohydrate intake (−0.07 [−0.11, −0.02] %, P = 0.004). The associations with protein (P = 7.5 × 10−9) and total energy (P = 0.002) were attenuated but remained significant after adjustment for BMI. We did not find significant interactions between the FTO variant and dietary intake of total energy, protein, carbohydrate or fat on BMI. Our findings suggest a positive association between the BMI-increasing allele of FTO variant and higher dietary protein intake and offer insight into potential link between FTO, dietary protein intake and adiposit
Multiple-subgenotype infections of Giardia intestinalis detected in Palestinian clinical cases using a subcloning approach
The Physics of Star Cluster Formation and Evolution
© 2020 Springer-Verlag. The final publication is available at Springer via https://doi.org/10.1007/s11214-020-00689-4.Star clusters form in dense, hierarchically collapsing gas clouds. Bulk kinetic energy is transformed to turbulence with stars forming from cores fed by filaments. In the most compact regions, stellar feedback is least effective in removing the gas and stars may form very efficiently. These are also the regions where, in high-mass clusters, ejecta from some kind of high-mass stars are effectively captured during the formation phase of some of the low mass stars and effectively channeled into the latter to form multiple populations. Star formation epochs in star clusters are generally set by gas flows that determine the abundance of gas in the cluster. We argue that there is likely only one star formation epoch after which clusters remain essentially clear of gas by cluster winds. Collisional dynamics is important in this phase leading to core collapse, expansion and eventual dispersion of every cluster. We review recent developments in the field with a focus on theoretical work.Peer reviewe
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