525 research outputs found
Interpretations of Slope Through Written and Verbal Interactions Between a Student and Her Tutors in Algebra 1
There is an ongoing need to support students’ learning of linear functions, and the study of slope makes up a foundational component of this learning. We applied techniques from systemic functional linguistics to document the meanings that were established through spoken interaction between a student and her tutors during discussions of slope. We found that, while fraction notation gave the student and tutors a common reference point to discuss slope, it also masked important differences in how the student interpreted slope compared to her tutors. The findings of this analysis imply the need not only to attend to how students quantify slope, but also whether students recognize slope as an attribute of a line
Far-ultraviolet Spectroscopy of Venus and Mars at 4 A Resolution with the Hopkins Ultraviolet Telescope on Astro-2
Far-ultraviolet spectra of Venus and Mars in the range 820-1840 A at 4 A
resolution were obtained on 13 and 12 March 1995, respectively, by the Hopkins
Ultraviolet Telescope (HUT), which was part of the Astro-2 observatory on the
Space Shuttle Endeavour. Longward of 1250 A, the spectra of both planets are
dominated by emission of the CO Fourth Positive band system and strong OI and
CI multiplets. In addition, CO Hopfield-Birge bands, B - X (0,0) at 1151 A and
C - X (0,0) at 1088 A, are detected for the first time, and there is a weak
indication of the E - X (0,0) band at 1076 A in the spectrum of Venus. The B -
X band is blended with emission from OI 1152. Modeling the relative intensities
of these bands suggests that resonance fluorescence of CO is the dominant
source of the emission, as it is for the Fourth Positive system. Shortward of
Lyman-alpha, other emission features detected include OII 834, OI lambda 989,
HI Lyman-beta, and NI 1134 and 1200. For Venus, the derived disk brightnesses
of the OI, OII, and HI features are about one-half of those reported by Hord et
al. (1991) from Galileo EUV measurements made in February 1990. This result is
consistent with the expected variation from solar maximum to solar minimum. The
ArI 1048, 1066 doublet is detected only in the spectrum of Mars and the derived
mixing ratio of Ar is of the order of 2%, consistent with previous
determinations.Comment: 8 pages, 5 figures, accepted for publication in ApJ, July 20, 200
POMK regulates dystroglycan function via LARGE-mediated elongation of matriglycan
Matriglycan [-GlcA-β1,3-Xyl-α1,3-]n serves as a scaffold in many tissues for extracellular matrix proteins containing laminin-G domains including laminin, agrin, and perlecan. Like-acetylglucosaminyltransferase-1 (LARGE1) synthesizes and extends matriglycan on α-dystroglycan (α-DG) during skeletal muscle differentiation and regeneration; however, the mechanisms which regulate matriglycan elongation are unknown. Here, we show that Protein O-Mannose Kinase (POMK), which phosphorylates mannose of core M3 (GalNac-β1,3-GlcNac-β1,4-Man) preceding matriglycan synthesis, is required for LARGE1-mediated generation of full-length matriglycan on α-DG (~150 kDa). In the absence of Pomk in mouse skeletal muscle, LARGE1 synthesizes a very short matriglycan resulting in a ~90 kDa α-DG which binds laminin but cannot prevent eccentric contraction-induced force loss or muscle pathology. Solution NMR spectroscopy studies demonstrate that LARGE1 directly interacts with core M3 and binds preferentially to the phosphorylated form. Collectively, our study demonstrates that phosphorylation of core M3 by POMK enables LARGE1 to elongate matriglycan on α-DG, thereby preventing muscular dystrophy
Estimating the costs for the treatment of abortion complications in two public referral hospitals: a cross-sectional study in Ouagadougou, Burkina Faso
Treatment costs of induced abortion complications can consume a substantial amount of hospital resources. This use of hospitals scarce resources to treat induced abortion complications may affect hospitals’ capacities to deliver other health care services. In spite of the importance of studying the burden of the treatment of induced abortion complications, few studies have been conducted to document the costs of treating abortion complications in Burkina Faso. Our objective was to estimate the costs of six abortion complications including incomplete abortion, hemorrhage, shock, infection/sepsis, cervix or vagina laceration, and uterus perforation treated in two public referral hospital facilities in Ouagadougou and the cost saving of providing safe abortion care services
Far‐UV emissions from the SL9 impacts with Jupiter
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/95348/1/grl8617.pd
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