Get your facts right : preschoolers systematically extend both object names and category-relevant facts

There is an ongoing debate over the extent to which language development shares common processing mechanisms with other domains of learning. It is well-established that toddlers will systematically extend object labels to similarly-shaped category exemplars (e.g., Landau, Smith, & Jones, 1988; Markman & Hutchinson, 1984). However, previous research is inconclusive as to whether young children will similarly extend factual information about an object to other category members. We explicitly contrast facts varying in category relevance, and test for extension using two different tasks. Three- to four-year-olds (N = 61) were provided with one of three types of information about a single novel object: a category-relevant fact (‘it’s from a place called Modi’), a category-irrelevant fact (‘my uncle gave it to me’), or an object label (‘it’s called a Modi’). At test, children provided with the object name or category-relevant fact were significantly more likely to display systematic category extension than children who learnt the category-irrelevant fact. Our findings contribute to a growing body of evidence that the mechanisms responsible for word learning may be domain-general in nature

Young children retain fast mapped object labels better than shape, color, and texture words

We compared short- and long-term retention of fast mapped color, shape and texture words as well as object labels. In an exposure session, 354 3- and 4-year-old children were shown a set of two familiar and three novel stimuli. One of the novel stimuli was labeled with a new object label, color, shape or texture word. Retention of the mapping between the new word and the novel object or property was measured either five minutes or one week later. After five minutes, retention was significantly above chance in all conditions. However, after one week only the mappings for object labels were retained above chance levels. Our findings suggest that fast mapped object labels are retained long-term better than color, shape and texture words. The results also highlight the importance of comparing short- and long-term retention when studying children’s word learning

Mixed sand and gravel beaches: accurate measurement of active layer depth to develop predictive models of sediment transport

This thesis addresses the need to calibrate longshore sediment transport equations for use on heavily managed mixed sediment beaches, which are becoming increasingly common but are still relatively understudied. This is achieved through the use of active layer measurements, tracer pebble experiments, and monitoring of morphodynamics over a total period of 16 months. It is unique in investigating a complex, artificially replenished, groyned mixed sand and gravel beach in this way. The groynes have a significant impact on beach morphology and sediment transport at Eastoke. Beach levels were monitored using repeated profiles at three main locations within a groyne cell, allowing for the effect of these structures on beach profile shape and response to changing wave climates to be assessed. This provides a more accurate representation of morphodynamics than would otherwise be available from semi-annual profile surveys. The beach response to hydrodynamic conditions was shown to be rapid, and not always indicative of drift direction. Sediment sorting was observed, but was not strongly correlated with wave conditions. A vast dataset of active layer measurements indicated significant variability, which has not been made clear by previous studies of active layer depth. The key finding of this thesis is that active layer depth as a percentage of wave height can be predicted from significant wave height using the equation ln(y) = -0.797x + 3.565 (R2 = 0.578), and this value can then be converted into a depth measurement. The prediction can be applied at a daily scale to the combined upper and mid beach as an estimate of the average active layer depth. Further field sites should be investigated to determine whether this equation can be applied to other mixed sediment beaches. Short- and medium-term pebble transport patterns were observed using passive integrated transponder (PIT) tagged pebbles, deployed in stages throughout the research. Sediment transport volumes were estimated based on field data, and hydrodynamic data used to calculate a range of drift coefficients (k) for the commonly used CERC transport formula. Low detection rates ultimately limit the confidence which can be applied to final calculations of longshore transport volumes and values of k, but this study provides insight into the complexities associated with studying a site like this, and suggestions for improvements which could be made to future research

A comparison of sex offenders and other types of offenders referred to intellectual disability forensic services

This study compared 131 sex offenders with ID and 346 other types of offenders with ID using case file records. All the females in the study were non sexual offenders. Significantly more sexual offenders were referred from court and criminal justice services while significantly fewer were referred from secondary healthcare. A higher percentage of sex offenders had some form of legal status at time of referral. Greater proportions of non sexual offenders were referred for aggression, damage to property, substance abuse and fire setting while only the sex offenders had an index sex offence. For previous offending, the non sexual offenders had higher rates of aggression, cruelty and neglect of children, property damage and substance abuse while the sexual offenders had higher rates of previous sexual offending. For psychiatric disturbance and adversity in childhood, only ADHD showed a significant difference between groups with the non sexual offenders recording higher rates

Does the Affirmative Consent Standard Increase the Accuracy of Sexual Assault Perceptions? It Depends on How You Learn About the Standard

Objective: Colleges and universities are increasingly adopting affirmative consent standards of sexual assault, in which consent is defined as conscious and voluntary “yeses” given throughout a sexual interaction. We examined the impact of affirmative consent standards on perceptions of assault and consent. Hypotheses: We hypothesized that in sexual assault scenarios involving physical force or verbal coercion, exposure to the consent standard would increase perceptions of assault and decrease perceptions of consent relative to not being exposed to the standard. We then explored whether dehumanization of the perpetrator or the victim mediates the association between assault type and sexual assault perceptions and how this relation changes on the basis of exposure to the affirmative consent standard. Method: We exposed 909 participants (predominantly women: n = 574; predominantly White: n = 677; age: M = 28.61 years, SD = 11.10; students: n = 363, Mechanical Turk workers: n = 546) to an affirmative consent standard in a written policy, a video using a “cup-of-tea” metaphor to describe the consent standard, or no information on the standard. Participants rated perceptions of assault, consent, and dehumanization of a man and woman involved in a sexual interaction involving physical force, verbal coercion, or a consensual agreement. Results:Participants who saw the affirmative consent video were more likely to perceive physical assault as assault compared with participants in the no-exposure control condition. Participants who read the affirmative consent definition were no more or less likely to perceive physical assault as sexual assault compared with participants in the control condition. Participants exposed to the text definition perceived the consensual interaction as more assaultive than did participants in the video and control conditions. Perpetrator dehumanization also emerged as a mediator of the relation between assault type and assault perceptions. Conclusions: These results suggest that exposure to consent standards sometimes aids sexual assault decision-making but also leads to confusion, even in scenarios in which consent is normally discernable. Public Significance: Many institutions of higher education use affirmative consent standards, or a “yes means yes” approach, in attempts to stop sexual assault. Empirical evidence on how these standards shape perceptions of assault is mixed. University offices of violence prevention and Title IX officers may benefit from considering the manner in which students are educated about consent standards to understand the impact of training on sexual assault decision-making. Includes Supplemental materials

Pharmacist-led management of chronic pain in primary care:results from a randomised controlled exploratory trial

To compare the effectiveness of pharmacist medication review, with or without pharmacist prescribing, with standard care, for patients with chronic pain

Astrocyte-Specific Expression Patterns Associated with the PDGF-Induced Glioma Microenvironment

The tumor microenvironment contains normal, non-neoplastic cells that may contribute to tumor growth and maintenance. Within PDGF-driven murine gliomas, tumor-associated astrocytes (TAAs) are a large component of the tumor microenvironment. The function of non-neoplastic astrocytes in the glioma microenvironment has not been fully elucidated; moreover, the differences between these astrocytes and normal astrocytes are unknown. We therefore sought to identify genes and pathways that are increased in TAAs relative to normal astrocytes and also to determine whether expression of these genes correlates with glioma behavior.We compared the gene expression profiles of TAAs to normal astrocytes and found the Antigen Presentation Pathway to be significantly increased in TAAs. We then identified a gene signature for glioblastoma (GBM) TAAs and validated the expression of some of those genes within the tumor. We also show that TAAs are derived from the non-tumor, stromal environment, in contrast to the Olig2+ tumor cells that constitute the neoplastic elements in our model. Finally, we validate this GBM TAA signature in patients and show that a TAA-derived gene signature predicts survival specifically in the human proneural subtype of glioma.Our data identifies unique gene expression patterns between populations of TAAs and suggests potential roles for stromal astrocytes within the glioma microenvironment. We show that certain stromal astrocytes in the tumor microenvironment express a GBM-specific gene signature and that the majority of these stromal astrocyte genes can predict survival in the human disease

Transition from community dwelling to retirement village in older adults:cognitive functioning and psychological health outcomes

Supported living and retirement villages are becoming a significant option for older adults with impairments, with independence concerns or for forward planning in older age, but evidence as to psychological benefits for residents is sparse. This study examined the hypothesis that the multi-component advantages of moving into a supported and physically and socially accessible ‘extra-care’ independent living environment will impact on psychological and functioning measures. Using an observational longitudinal design, 161 new residents were assessed initially and three months later, in comparison to 33 older adults staying in their original homes. Initial group differences were apparent but some reduced after three months. Residents showed improvement in depression, perceived health, aspects of cognitive function and reduced functional limitations, while controls showed increased functional limitations (worsening). Ability to recall specific autobiographical memories, known to be related to social problem solving, depression and functioning in social relationships, predicted change in communication limitations, and cognitive change predicted changes in recreational limitations. Change in anxiety and memory predicted change in depression. Findings suggest that older adults with independent living concerns who move to an independent but supported environment can show significant benefits in psychological outcomes and reduction in perceived impact of health on functional limitations in a short period. Targets for focused rehabilitation are indicated, but findings also validate development of untargeted general supportive environments