Effect of immediate dentine sealing on the aging and fracture strength of lithium disilicate inlays and overlays

Objectives: The objectives of this study were to compare the in vitro, laboratory aging, fracture strength, failure mode and reparability of molars restored with lithium disilicate inlays and overlays in conjunction with or without immediate dentin sealing (IDS). Methods: Forty extracted, sound human molars were selected and divided into four groups: 1) Inlays with IDS; 2) Inlays without IDS; 3) Overlays with IDS; 4) Overlays without IDS. Standard MOD preparations were made (3 mm wide, 5 mm deep) and in groups 2 and 4, all the cusps were reduced by 2 mm. Directly following tooth preparation, IDS was applied in specimens belonging to groups 1 and 3. The indirect restorations were luted with a heated composite. The restored teeth were subsequently challenged during aging (1.2 million cycles) and thermocycling loading (8000 cycles, 5–55 degrees C). Subsequently, the fracture strength was tested by a load to failure test at 45°. A failure analysis was performed using light- and scanning electron microscopy. The results were analyzed using two-way ANOVA and a Fisher exact test. Results: Mean fracture load + SD (N) were: Group 1 (n = 12): 1610 ± 419; Group 2 (n = 12): 1115 ± 487; Group 3 (n = 12): 2011 ± 496; Group 4 (n = 12): 1837 ± 406. Teeth restored with an onlay were stronger than those restored with an inlay restoration (p <.001). Teeth with IDS were stronger overall than those without IDS (p =.026). The interaction between preparation type and the mode of dentin conditioning had no statistically significant influence on fracture strength (p =.272). Subsequently, custom hypothesis tests showed that there was no statistically significant difference in fracture strength between inlays with IDS and overlays without IDS (p =.27). Overlays tend to fail in a more destructive, non-reparable way (p =.003). Significance: Both variables IDS and overlay preparation improve overall fracture strength. Inlays with IDS and overlays without IDS didn't differ in fracture strength. Both inlays and overlays are strong enough to withstand physiological chewing forces

Велес – повелитель мертвих

In providing advice on herd health, veterinarians need to be aware of farmers' goals and priorities. To determine the level of awareness, 29 veterinarians from 15 practices completed questionnaires during visits to dairy farms within the scope of veterinary herd health management (VHHM) programmes. The farmers (n = 30) were asked to complete a questionnaire and their discussions with the veterinarian were recorded using a voice recorder. Herd performance goals were set by the farmer and veterinarian in 24% of cases. Veterinarians who did not set goals indicated that they and the farmer 'intuitively knew' what each wanted to achieve, and that the setting of performance goals was considered 'too formal'. Veterinarians often could not identify a farmer's main goal, and typically found milk production and nutrition significantly more important (P <0.01, and P <0.02, respectively), and fertility significantly less important (P <0.01) than the farmers. During on-farm conversations, veterinarians did not actively seek to identify farmers' goals or problems, suggest a co-operative strategy or summarise any advice given. The findings of this survey suggest that veterinarians need to focus more on goal setting, since awareness of goals and priorities is important for both communication and compliance with advice given. The needs of farmers with respect to herd health should also be more actively sought by veterinarians as the findings indicate that most farmers do not readily volunteer such information. (C) 2013 Published by Elsevier Ltd

Practices in antenatal counseling for extremely premature infants amongst European trainees

Item does not contain fulltextThere is no international consensus on content and process regarding antenatal counseling in extreme prematurity. The need for adequate training is increasingly recognized. This descriptive study evaluates current practice in antenatal counseling amongst European trainees using an online survey. Focusing on the process, the majority of respondents did not have a medical consensus guideline. Seven percent of the trainees received some formal training. Focusing on the content, about half of the subjects did not mention any statistics about mortality. CONCLUSION: We observed wide variation in actual content and organization in antenatal counseling in Europe amongst European trainees in neonatology

Professionals' preferences in prenatal counseling at the limits of viability: a nationwide qualitative Dutch study

Item does not contain fulltextPrenatal counseling practices at the limits of viability do vary, and constructing a counseling framework based on guidelines, professional and parental preferences, might achieve more homogeneity. We aimed to gain insight into professionals' preferences on three domains of counseling, particularly content, organization, and decision making and their influencing factors. A qualitative, nationwide in-depth exploration among Dutch perinatal professionals by semi-structured interviews in focus groups was performed. Regarding content of prenatal counseling, preparing parents on the short-term situation (delivery room care) and revealing their perspectives on "quality of life" were considered important. Parents should be informed on the kind of decision, on the difficulty of individual outcome predictions, on survival and mortality figures, short- and long-term morbidity, and the burden of hospitalization. For organization, the making of and compliance with agreements between professionals may promote joint counseling by neonatologists and obstetricians. Supportive materials were considered useful but only when up-to-date, in addition to the discussion and with opportunity for personalization. Regarding decision making, it is not always clear to parents that a prenatal decision needs to be made and they can participate, influencing factors could be, e.g., unclear language, directive counseling, overload of information, and an immediate delivery. There is limited familiarity with shared decision making although it is the preferred model. CONCLUSION: This study gained insight into preferred content, organization, and decision making of prenatal counseling at the limits of viability and their influencing factors from a professionals' perspective. What is Known: * Heterogeneity in prenatal counseling at the limits of viability exists * Differences between preferred counseling and actual practice also exists What is New: * Insight into preferred content, organization, and decision making of prenatal periviability counseling and its influencing factors from a professionals' perspective. Results should be taken into account when performing counseling. * Particularly the understanding of true shared decision making needs to be improved. Furthermore, implementation of shared decision making in daily practice needs more attention

Dutch guidelines on care for extremely premature infants:Navigating between personalisation and standardization

OBJECTIVE: There is no international consensus on what type of guideline is preferred for care at the limit of viability. We aimed to conceptualize what type of guideline is preferred by Dutch healthcare professionals: 1) none; 2) gestational-age-based; 3) gestational-age-based-plus; or 4) prognosis-based via a survey instrument. Additional questions were asked to explore the grey zone and attitudes towards treatment variation. FINDING: 769 surveys were received. Most of the respondents (72.8%) preferred a gestational-age-based-plus guideline. Around 50% preferred 24+0/7 weeks gestational age as the lower limit of the grey zone, whereas 26+0/7 weeks was the most preferred upper limit. Professionals considered treatment variation acceptable when it is based upon parental values, but unacceptable when it is based upon the hospital's policy or the physician's opinion. CONCLUSION: In contrast to the current Dutch guideline, our results suggest that there is a preference to take into account individual factors besides gestational age

Costs of Rabies Control: An Economic Calculation Method Applied to Flores Island

Background: Rabies is a zoonotic disease that, in most human cases, is fatal once clinical signs appear. The disease transmits to humans through an animal bite. Dogs are the main vector of rabies in humans on Flores Island, Indonesia, resulting in about 19 human deaths each year. Currently, rabies control measures on Flores Island include mass vaccination and culling of dogs, laboratory diagnostics of suspected rabid dogs, putting imported dogs in quarantine, and pre-and post-exposure treatment (PET) of humans. The objective of this study was to estimate the costs of the applied rabies control measures on Flores Island. Methodology/principal findings: A deterministic economic model was developed to calculate the costs of the rabies control measures and their individual cost components from 2000 to 2011. The inputs for the economic model were obtained from (i) relevant literature, (ii) available data on Flores Island, and (iii) experts such as responsible policy makers and veterinarians involved in rabies control measures in the past. As a result, the total costs of rabies control measures were estimated to be US$1.12 million (range: US$0.60-1.47 million) per year. The costs of culling roaming dogs were the highest portion, about 39 percent of the total costs, followed by PET (35 percent), mass vaccination (24 percent), pre-exposure treatment (1.4 percent), and others (1.3 percent) (dog-bite investigation, diagnostic of suspected rabid dogs, trace-back investigation of human contact with rabid dogs, and quarantine of imported dogs). Conclusions/significance: This study demonstrates that rabies has a large economic impact on the government and dog owners. Control of rabies by culling dogs is relatively costly for the dog owners in comparison with other measures. Providing PET for humans is an effective way to prevent rabies, but is costly for government and does not provide a permanent solution to rabies in the future

Effectiveness of High Fidelity Video-Assisted Real-Time Simulation: A Comparison of Three Training Methods for Acute Pediatric Emergencies

Background. Video-assisted real-time simulation (VARS) offers the possibility of developing competence in acute medicine in a realistic and safe environment. We investigated the effectiveness of the VARS model and compared it with educational methods like Problem-Based Learning (PBL) and Pediatric Advanced Life Support (PALS). Methods. 45 fourth-year medical students were randomized for three educational methods. Level of knowledge and self-efficacy were measured before and after intervention. Clinical performance was measured by a blinded observer using a video checklist of prescripted scenarios on a high-fidelity simulator. Results. Knowledge test and self-efficacy scores improved significantly (P < 0.001) without differences between educational groups. The VARS group showed significantly (P < 0.05) higher scores on both postintervention scenarios concerning structure and time. Conclusion. VARS training is an effective educational method teaching pediatric acute care skills in the undergraduate curriculum. When compared to PBL and PALS training, VARS training appears to be superior in enhancing short-term clinical performance

HD 144432: a young triple system

We present new imaging and spectroscopic data of the young Herbig star HD 144432 A, which was known to be a binary star with a separation of 1.47 arcsec. High-resolution NIR imaging data obtained with NACO at the VLT reveal that HD 144432 B itself is a close binary pair with a separation of 0.1 arcsec. High-resolution optical spectra, acquired with FEROS at the 2.2m MPG/ESO telescope in La Silla, of the primary star and its co-moving companions were used to determine their main stellar parameters such as effective temperature, surface gravity, radial velocity, and projected rotational velocity by fitting synthetic spectra to the observed stellar spectra. The two companions, HD 144432 B and HD 144432 C, are identified as low-mass T Tauri stars of spectral type K7V and M1V, respectively. From the position in the HRD the triple system appears to be co-eval with a system age of 6+/-3 Myr.Comment: Accepted for publication in Astronomy & Astrophysics, 4 pages, 4 figure