1,384 research outputs found

    Anal signs of child sexual abuse: a case–control study

    Get PDF
    Background: There is uncertainty about the nature and specificity of physical signs following anal child sexual abuse. The study investigates the extent to which physical findings discriminate between children with and without a history of anal abuse.<p></p> Methods: Retrospective case note review in a paediatric forensic unit.<p></p> Cases: all eligible cases from 1990 to 2007 alleging anal abuse.<p></p> Controls: all children examined anally from 1998 to 2007 with possible physical abuse or neglect with no identified concern regarding sexual abuse. Fisher’s exact test (two-tailed) was performed to ascertain the significance of differences for individual signs between cases and controls. To explore the potential role of confounding, logistic regression was used to produce odds ratios adjusted for age and gender.<p></p> Results: A total of 184 cases (105 boys, 79 girls), average age 98.5 months (range 26 to 179) were compared with 179 controls (94 boys, 85 girls) average age 83.7 months (range 35–193). Of the cases 136 (74%) had one or more signs described in anal abuse, compared to 29 (16%) controls. 79 (43%) cases and 2 (1.1%) controls had >1 sign. Reflex anal dilatation (RAD) and venous congestion were seen in 22% and 36% of cases but <1% of controls (likelihood ratios (LR) 40, 60 respectively), anal fissure in 14% cases and 1.1% controls (LR 13), anal laxity in 27% cases and 3% controls (LR 10).<p></p> Novel signs seen significantly more commonly in cases were anal fold changes, swelling and twitching. Erythema, swelling and fold changes were seen most commonly within 7 days of last reported contact; RAD, laxity, venous congestion, fissure and twitching were observed up to 6 months after the alleged assault.<p></p> Conclusions: Anal findings are more common in children alleging anal abuse than in those presenting with physical abuse or neglect with no concern about sexual abuse. Multiple signs are rare in controls and support disclosed anal abuse

    3-D kinematic comparison of treadmill and overground running.

    Get PDF
    Studies investigating the mechanics of human movement are often conducted using the treadmill. The treadmill is an attractive device for the analysis of human locomotion. Studies comparing overground and treadmill running have analyzed discrete variables, however differences in excursion from footstrike to peak angle and range of motion during stance have yet to be examined. This study aimed to examine the 3-D kinematics of the lower extremities during overground and treadmill locomotion to determine the extent to which the two modalities differ. Twelve participants ran at 4.0m/s in both treadmill and overground conditions. 3-D angular kinematic parameters during the stance phase were collected using an eight camera motion analysis system. Hip, knee and ankle joint kinematics were quantified in the sagittal, coronal and transverse planes, then compared using paired t-tests. Of the parameters analyzed hip flexion at footstrike 12° hip range of motion 17°, peak hip flexion 12.7°, hip transverse plane range of motion 8° peak knee flexion 5° and peak ankle excursion range 6.6°, coronal plane ankle angle at toe-off 6.5° and peak ankle eversion 6.3° were found to be significantly different. These results lead to the conclusion that the mechanics of treadmill locomotion cannot be generalized to overground

    The influence of barefoot and barefoot inspired footwear on the kinetics and kinematics of running in comparison to conventional running shoes.

    Get PDF
    Barefoot running has experienced a resurgence in footwear biomechanics literature, based on the supposition that it serves to reduce the occurrence of overuse injuries in comparison to conventional shoe models. This consensus has lead footwear manufacturers to develop shoes which aim to mimic the mechanics of barefoot locomotion. This study compared the impact kinetics and 3-D joint angular kinematics observed whilst running: barefoot, in conventional cushioned running shoes and in shoes designed to integrate the perceived benefits of barefoot locomotion. The aim of the current investigation was therefore to determine whether differences in impact kinetics exist between the footwear conditions and whether shoes which aim to simulate barefoot movement patterns can closely mimic the 3-D kinematics of barefoot running. Twelve participants ran at 4.0 m.s-1±5% in each footwear condition. Angular joint kinematics from the hip, knee and ankle in the sagittal, coronal and transverse planes were measured using an eight camera motion analysis system. In addition simultaneous tibial acceleration and ground reaction forces were obtained. Impact parameters and joint kinematics were subsequently compared using repeated measures ANOVAs. The kinematic analysis indicates that in comparison to the conventional and barefoot inspired shoes that running barefoot was associated significantly greater plantar-flexion at footstrike and range of motion to peak dorsiflexion. Furthermore, the kinetic analysis revealed that compared to the conventional footwear impact parameters were significantly greater in the barefoot condition. Therefore this study suggests that barefoot running is associated with impact kinetics linked to an increased risk of overuse injury, when compared to conventional shod running. Furthermore, the mechanics of the shoes which aim to simulate barefoot movement patterns do not appear to closely mimic the kinematics of barefoot locomotion

    The coupling of a young stellar disc with the molecular torus in the Galactic centre

    Full text link
    The Galactic centre hosts, according to observations, a number of early-type stars. About one half of those which are orbiting the central supermassive black hole on orbits with projected radii \gtrsim 0.03 pc form a coherently rotating disc. Observations further reveal a massive gaseous torus and a significant population of late-type stars. In this paper, we investigate, by means of numerical N-body computations, the orbital evolution of the stellar disc, which we consider to be initially thin. We include the gravitational influence of both the torus and the late-type stars, as well as the self-gravity of the disc. Our results show that, for a significant set of system parameters, the evolution of the disc leads, within the lifetime of the early-type stars, to a configuration compatible with the observations. In particular, the disc naturally reaches a specific - perpendicular - orientation with respect to the torus, which is indeed the configuration observed in the Galactic centre. We, therefore, suggest that all the early-type stars may have been born within a single gaseous disc.Comment: Accepted for publication in MNRAS; 9 pages, 4 figures, 1 tabl

    Quiet Supersonic Flights 2018 (QSF18) Test: Galveston, Texas Risk Reduction for Future Community Testing with a Low-Boom Flight Demonstration Vehicle

    Get PDF
    The Quiet Supersonic Flights 2018 (QSF18) Program was designed to develop tools and methods for demonstration of overland supersonic flight with an acceptable sonic boom, and collect a large dataset of responses from a representative sample of the population. Phase 1 provided the basis for a low amplitude sonic boom testing in six different climate regions that will enable international regulatory agencies to draft a noise-based standard for certifying civilian supersonic overland flight. Phase 2 successfully executed a large scale test in Galveston, Texas, developed well documented data sets, calculated dose response relationships, yielded lessons, and identified future risk reduction activities

    Broken discs: warp propagation in accretion discs

    Full text link
    We simulate the viscous evolution of an accretion disc around a spinning black hole. In general any such disc is misaligned, and warped by the Lense-Thirring effect. Unlike previous studies we use effective viscosities constrained to be consistent with the internal fluid dynamics of the disc. We find that nonlinear fluid effects, which reduce the effective viscosities in warped regions, can promote the breaking of the disc into two distinct planes. This occurs when the Shakura & Sunyaev dimensionless viscosity parameter alpha is ~ 45 degrees. The break can be a long-lived feature, propagating outwards in the disc on the usual alignment timescale, after which the disc is fully co- or counter-aligned with the hole. Such a break in the disc may be significant in systems where we know the inclination of the outer accretion disc to the line of sight, such as some X-ray binaries: the inner disc, and so any jets, may be noticeably misaligned with respect to the orbital plane.Comment: 8 pages, 9 figures. Accepted for publication in MNRA

    Rapid Detection of Botulinum Neurotoxins—A Review

    Get PDF
    A toxin is a poisonous substance produced within living cells or organisms. One of the most potent groups of toxins currently known are the Botulinum Neurotoxins (BoNTs). These are so deadly that as little as 62 ng could kill an average human; to put this into context that is approximately 200,000 × less than the weight of a grain of sand. The extreme toxicity of BoNTs leads to the need for methods of determining their concentration at very low levels of sensitivity. Currently the mouse bioassay is the most widely used detection method monitoring the activity of the toxin; however, this assay is not only lengthy, it also has both cost and ethical issues due to the use of live animals. This review focuses on detection methods both existing and emerging that remove the need for the use of animals and will look at three areas; speed of detection, sensitivity of detection and finally cost. The assays will have wide reaching interest, ranging from the pharmaceutical/clinical industry for production quality management or as a point of care sensor in suspected cases of botulism, the food industry as a quality control measure, to the military, detecting BoNT that has been potentially used as a bio warfare agent

    Supernova Kicks and Misaligned Microquasars

    Full text link
    The low-mass X-ray binary microquasar GRO J1655-40 is observed to have a misalignment between the jets and the binary orbital plane. Since the current black hole spin axis is likely to be parallel to the jets, this implies a misalignment between the spin axis of the black hole and the binary orbital plane. It is likely the black holes formed with an asymmetric supernova which caused the orbital axis to misalign with the spin of the stars. We ask whether the null hypothesis that the supernova explosion did not affect the spin axis of the black hole can be ruled out by what can be deduced about the properties of the explosion from the known system parameters. We find that this null hypothesis cannot be disproved but we find that the most likely requirements to form the system include a small natal black hole kick (of a few tens of km/s) and a relatively wide pre-supernova binary. In such cases the observed close binary system could have formed by tidal circularisation without a common envelope phase.Comment: Accepted for publication in MNRA

    Reviews

    Get PDF
    Tolkien, Race and Cultural History: From Fairies to Hobbits. Dimitra Fimi. Reviewed by Jason Fisher. Charles Williams and his Contemporaries. Suzanne Bray and Richard Sturch, eds. Reviewed by Joe R. Christopher. In the Land of Invented Languages: Esperanto Rock Stars, Klingon Poets, Loglan Lovers, and the Mad Dreamers who Tried to Build a Perfect Language. Arika Okrent. Reviewed by Harley J. Sims. Millennial Mythmaking: Essays on the Power of Science Fiction and Fantasy Literature, Films and Games. John Perlich & David Whitt, eds. Reviewed by Priscilla Hobbs Middle-earth Minstrel: Essays on Music in Tolkien. Bradford Lee Eden, ed. Reviewed by Emily A. Moniz. Harry Potter & Imagination: The Way Between Two Worlds. Travis Prinzi. Reviewed by David D. Oberhelman. Fastitocalon: Studies in Fantasticism Ancient to Modern: Immortals and the Undead. Eds. Thomas Honneger and Fanfan Chen. Reviewed by Janet Brennan Croft. Theodor Seuss Geisel [sic]. Donald E. Pease. Reviewed by Joe R. Christopher
    corecore