265 research outputs found

    Keeping the hope for tomorrow : Community Development in Aida Refugee Camp

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    Master in Community Development and Social Innovation, VID Specialized University, Stavanger, May 2021This research sought to see how Alrowwad as an organization in Aida refugee camp worked to better their community through the arts. The specific topic was how the organization faced and worked through the difficulties of the situation in occupied Palestine and how resisting the occupation was part of the organization’s Community Development. Though the field of Community Development has amassed a lot of research, there is very little research done on what community Development looks like and how it works in Palestine and communities under occupation. The paper also includes global dimensions of international donation and volunteering, as well as stereotypes and structures of power. The findings are based on semi-structured interviews and theories of critical approach to community development, asset and need-based approach to community development, art and community development and a report on Palestinian Youth´s aspirations and challenges.submittedVersio

    Etiological Perspectives of ABDL Behavior from Members of an Online ABDL Community

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    Atypical sexual behavior is often viewed from a perspective of pathology and non-clinical samples are not typically used in research. The current exploratory research is a qualitative study that examined the etiological perspectives of Adult Baby/ Diaper Lover (ABDL) behavior from members of an online ABDL community. Archival survey data from an online sample (N = 1,795) of ABDL participants were used. The theories informing this research included attachment theory and the sexual health model. Research questions included an examination of: (a) what we can be learn from the way an ABDL individual perceives the origin of ABDL behavior, (b) differences in the way participants find their ABDL interests, and (c) the origin beliefs of participants from a community sample compare to the results from historical data. Thematic analysis was used to analyze the archival survey data, and grounded theory was used to forward a theory about the etiology of ABDL. Participants suggested that ABDL may not be the result of a mental health condition or a trauma history. The majority of participants believe their ABDL behaviors are connected to childhood experiences, which partially dovetails with current theories on the etiology of paraphilias. Although some participants believe ABDL behaviors are related to toilet training, most do not. Most participants endorse a wide range of explanations for their ABDL interests and behaviors. The environmental shaping theory of ABDL is based on data from this study and both supports and conflicts with historical research on paraphilia. This study contributes to positive social change by allowing clinicians and scholars the opportunity to hear the voices of a stigmatized group and understand them better. An increased awareness of sexual diversity can allow for greater acceptance and less stigmatization in the mental health and medical fields

    The importance of EU as an external factor on democratic consolidation. The cases of the Czech Republic and Slovakia

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    The breakdown of communist rule in Central and Eastern Europe has offered scholars in the field of transition and regime change theory, and comparative politics in general, a major opportunity to test out former theories, but also formulate new ones. Obviously, no theory is alone applicable to the complexity of the transitions. There is a variety of cases, each with distinct developments before, during and after the transition to democracy has been completed. Some common features are still possible to extract when studying regime change in a region. As for Central and Eastern Europe, one of the most outstanding characteristics of the transition to democracy has been the visibility and importance of external factors. Previously the view was held that external factors were essentially secondary to domestic processes of regime change. The studies on Central and Eastern Europe carried out the last 15 years might show another picture, and that leads us to the core of this paper. How important have the external factors been? After providing the reader with some relevant theories on democracy and démocratisation, the focus is turned to the examination of external influences on transition in this region. In order to narrow down the complexity of the subject, the European Union has been chosen as the variable to...Department of Political ScienceKatedra politologieFakulta sociálních vědFaculty of Social Science

    The Forum: Spring 2006

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    Spring 2006 journal of the Honors Program at the University of North Dakota. The issue includes stories, poems, essays and art by undergraduate students.https://commons.und.edu/und-books/1059/thumbnail.jp

    Disinfection of Shared Mobile Phones Carried by Registered Nurses: A Comparison of Two Methods

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    This study determined the efficacy of cleaning products on mobile phones. Previous research has demonstrated the risk for bacterial cross contamination between healthcare workers\u27 hands, close contact equipment, and mobile communication devices. There is extensive literature on survival of organisms on inanimate objects. Mobile communication devices can act as a reservoir for bacteria associated with nosocomial infection. Additional studies show cross contamination between the healthcare workers hands, the mobile phones, and the patient.https://digitalcommons.centracare.com/nursing_posters/1025/thumbnail.jp

    You Missed a Spot! Disinfecting Shared Mobile Phones

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    The use of portable mobile devices has facilitated timely communication among healthcare team members. It\u27s now a common practice for hospital-owned mobile phones to be shared among healthcare employees from shift to shift. Despite the benefit of increased, timely communication between caregivers, sharing mobile devices can lead to the spread of healthcare-associated infections (HAIs). This article looks at the efficacy of two types of cleaning products on shared mobile phones carried by RNs at a 489-bed, Magnet-designated, Midwestern regional medical center. The cleaning methods evaluated were 70% isopropyl alcohol wipes and ethyl alcohol wipes

    Bacteria on Shared Mobile Phones Can Lead to Infections

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    It\u27s now a common practice for hospital-owned mobile phones to be shared among healthcare employees from shift to shift. Despite the benefit of increased, timely communication between caregivers, sharing mobile devices can lead to the spread of healthcare-associated infections (HAIs) if they aren\u27t properly disinfected. The Guidelines for Disinfection and Sterilization in Healthcare Facilities describe non-critical environmental surfaces as items that are frequently touched by the hand and may pose a risk of secondary infection transmission

    Co-transcriptional degradation of aberrant pre-mRNA by Xrn2

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    Eukaryotic protein-coding genes are transcribed as pre-mRNAs that are matured by capping, splicing and cleavage and polyadenylation. Although human pre-mRNAs can be long and complex, containing multiple introns and many alternative processing sites, they are usually processed co-transcriptionally. Mistakes during nuclear mRNA maturation could lead to potentially harmful transcripts that are important to eliminate. However, the processes of human pre-mRNA degradation are not well characterised in the human nucleus. We have studied how aberrantly processed pre-mRNAs are degraded and find a role for the 5′→3′ exonuclease, Xrn2. Xrn2 associates with and co-transcriptionally degrades nascent β-globin transcripts, mutated to inhibit splicing or 3′ end processing. Importantly, we provide evidence that many endogenous pre-mRNAs are also co-transcriptionally degraded by Xrn2 when their processing is inhibited by Spliceostatin A. Our data therefore establish a previously unknown function for Xrn2 and an important further aspect of pre-mRNA metabolism that occurs co-transcriptionally

    Risk Factors for CIED Infection After Secondary Procedures

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    OBJECTIVES This study aimed to identify risk factors for infection after secondary cardiac implantable electronic device (CIED) procedures. BACKGROUND Risk factors for CIED infection are not well defined and techniques to minimize infection lack supportive evidence. WRAP-IT (World-wide Randomized Antibiotic Envelope Infection Prevention trial), a large study that assessed the safety and efficacy of an antibacterial envelope for CIED infection reduction, offers insight into procedural details and infection prevention strategies. METHODS This analysis included 2,803 control patients from the WRAP-IT trial who received standard preoperative antibiotics but not the envelope (44 patients with major infections through all follow-up). A multivariate least absolute shrinkage and selection operator machine learning model, controlling for patient characteristics and procedural variables, was used for risk factor selection and identification. Risk factors consistently retaining predictive value in the model (appeared >10 times) across 100 iterations of imputed data were deemed significant. RESULTS Of the 81 variables screened, 17 were identified as risk factors with 6 being patient/device-related (nonmodifiable) and 11 begin procedure-related (potentially modifiable). Patient/device-related factors included higher number of previous CIED procedures, history of atrial arrhythmia, geography (outside North America and Europe), device type, and lower body mass index. Procedural factors associated with increased risk included longer procedure time, implant location (non-left pectoral subcutaneous), perioperative glycopeptide antibiotic versus nonglycopeptide, anticoagulant, and/or antiplatelet use, and capsulectomy. Factors associated with decreased risk of infection included chlorhexidine skin preparation and antibiotic pocket wash. CONCLUSIONS In WRAP-IT patients, we observed that several procedural risk factors correlated with infection risk. These results can help guide infection prevention strategies to minimize infections associated with secondary CIED procedures. (J Am Coll Cardiol EP 2022;8:101-111) (c) 2022 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)

    Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p

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    The RNA exosome processes and degrades RNAs in archaeal and eukaryotic cells. Exosomes from yeast and humans contain two active exoribonuclease components, Rrp6p and Dis3p/Rrp44p. Rrp6p is concentrated in the nucleus and the dependence of its function on the nine-subunit core exosome and Dis3p remains unclear. We found that cells lacking Rrp6p accumulate poly(A)+ rRNA degradation intermediates distinct from those found in cells depleted of Dis3p, or the core exosome component Rrp43p. Depletion of Dis3p in the absence of Rrp6p causes a synergistic increase in the levels of degradation substrates common to the core exosome and Rrp6p, but has no effect on Rrp6p-specific substrates. Rrp6p lacking a portion of its C-terminal domain no longer co-purifies with the core exosome, but continues to carry out RNA 3′-end processing of 5.8S rRNA and snoRNAs, as well as the degradation of certain truncated Rrp6-specific rRNA intermediates. However, disruption of Rrp6p–core exosome interaction results in the inability of the cell to efficiently degrade certain poly(A)+ rRNA processing products that require the combined activities of Dis3p and Rrp6p. These findings indicate that Rrp6p may carry out some of its critical functions without physical association with the core exosome
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