Numerical modeling of the wind flow over a transverse dune

Transverse dunes, which form under unidirectional winds and have fixed profile in the direction perpendicular to the wind, occur on all celestial objects of our solar system where dunes have been detected. Here we perform a numerical study of the average turbulent wind flow over a transverse dune by means of computational fluid dynamics simulations. We find that the length of the zone of recirculating flow at the dune lee --- the {\em{separation bubble}} --- displays a surprisingly strong dependence on the wind shear velocity, $u_{\ast}$: it is nearly independent of $u_{\ast}$ for shear velocities within the range between $0.2\,$ms and $0.8\,$ms but increases linearly with $u_{\ast}$ for larger shear velocities. Our calculations show that transport in the direction opposite to dune migration within the separation bubble can be sustained if $u_{\ast}$ is larger than approximately $0.39\,$ms, whereas a larger value of $u_{\ast}$ (about $0.49\,$ms) is required to initiate this reverse transport.Comment: 11 pages, 8 figure

InVerDa - co-existing Schema Versions Made Foolproof

In modern software landscapes multiple applications usually share one database as their single point of truth. All these applications will evolve over time by their very nature. Often former versions need to stay available, so database developers find themselves maintaining co-existing schema version of multiple applications in multiple versions. This is highly error-prone and accounts for significant costs in software projects, as developers realize the translation of data accesses between schema versions with hand-written delta code. In this demo, we showcase INVERDA, a tool for integrated, robust, and easy to use database versioning. We rethink the way of specifying the evolution to new schema versions. Using the richer semantics of a descriptive database evolution language, we generate all required artifacts automatically and make database versioning foolproof

Towards a Neuronally Consistent Ontology for Robotic Agents

The Collaborative Research Center for Everyday Activity Science & Engineering (CRC EASE) aims to enable robots to perform environmental interaction tasks with close to human capacity. It therefore employs a shared ontology to model the activity of both kinds of agents, empowering robots to learn from human experiences. To properly describe these human experiences, the ontology will strongly benefit from incorporating characteristics of neuronal information processing which are not accessible from a behavioral perspective alone. We, therefore, propose the analysis of human neuroimaging data for evaluation and validation of concepts and events defined in the ontology model underlying most of the CRC projects. In an exploratory analysis, we employed an Independent Component Analysis (ICA) on functional Magnetic Resonance Imaging (fMRI) data from participants who were presented with the same complex video stimuli of activities as robotic and human agents in different environments and contexts. We then correlated the activity patterns of brain networks represented by derived components with timings of annotated event categories as defined by the ontology model. The present results demonstrate a subset of common networks with stable correlations and specificity towards particular event classes and groups, associated with environmental and contextual factors. These neuronal characteristics will open up avenues for adapting the ontology model to be more consistent with human information processing.Comment: Preprint of paper accepted for the European Conference on Artificial Intelligence (ECAI) 2023 (minor typo corrections

The perception of dynamic and static facial expressions of happiness and disgust investigated by ERPs and fMRI constrained source analysis

A recent functional magnetic resonance imaging (fMRI) study by our group demonstrated that dynamic emotional faces are more accurately recognized and evoked more widespread patterns of hemodynamic brain responses than static emotional faces. Based on this experimental design, the present study aimed at investigating the spatio-temporal processing of static and dynamic emotional facial expressions in 19 healthy women by means of multi-channel electroencephalography (EEG), event-related potentials (ERP) and fMRI-constrained regional source analyses. ERP analysis showed an increased amplitude of the LPP (late posterior positivity) over centro-parietal regions for static facial expressions of disgust compared to neutral faces. In addition, the LPP was more widespread and temporally prolonged for dynamic compared to static faces of disgust and happiness. fMRI constrained source analysis on static emotional face stimuli indicated the spatio-temporal modulation of predominantly posterior regional brain activation related to the visual processing stream for both emotional valences when compared to the neutral condition in the fusiform gyrus. The spatio-temporal processing of dynamic stimuli yielded enhanced source activity for emotional compared to neutral conditions in temporal (e.g., fusiform gyrus), and frontal regions (e.g., ventromedial prefrontal cortex, medial and inferior frontal cortex) in early and again in later time windows. The present data support the view that dynamic facial displays trigger more information reflected in complex neural networks, in particular because of their changing features potentially triggering sustained activation related to a continuing evaluation of those faces. A combined fMRI and EEG approach thus provides an advanced insight to the spatio-temporal characteristics of emotional face processing, by also revealing additional neural generators, not identifiable by the only use of an fMRI approach

NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain

Signaling in apoptosis and inflammation is often mediated by proteins of the death domain superfamily in the Fas/FADD/Caspase-8 or the Apaf-1/Caspase-9 pathways. This superfamily currently comprises the death domain (DD), death effector domain (DED), caspase recruitment domain (CARD), and pyrin domain (PYD) subfamilies. The PYD subfamily is most abundant, but three-dimensional structures are only available for the subfamilies DD, DED, and CARD, which have an antiparallel arrangement of six alpha helices as common fold. This paper presents the NMR structure of PYD of NALP1, a protein that is involved in the innate immune response and is a component of the inflammasome. The structure of NALP1 PYD differs from all other known death domain superfamily structures in that the third alpha helix is replaced by a flexibly disordered loop. This unique feature appears to relate to the molecular basis of familial Mediterranean fever (FMF), a genetic disease caused by single-point mutations

Simulation of rotating drum experiments using non-circular particles

We investigate the flow of granular material in a rotating cylinder numerically using molecular dynamics in two dimensions. The particles are described by a new model which allows to simulate geometrically complicated shaped grains. The results of the simulation agree significantly better with experiments than the results which are based on circular particles.Comment: 15 pages, 9 figure

Исследование величины наклепанного слоя при обработке стали 40Х концевыми фрезами из быстрорежущей стали с разными углами винтовой стружечной канавки

Объект исследования – концевые фрезы из быстрорежущей стали Р6М5 с разными углами наклона винтовой стружечной канавки в 20°, 30°, 45° и концевая фреза с волнообразной режущей кромкой. Предмет исследования – влияние на величину наклепанного слоя после обработки фрезерованием стали 40Х. Цель. Исследовать величину наклепанного слоя при обработке стали 40Х концевыми фрезами из быстрорежущей стали с разными углами наклона винтовой канавки, выявить меньшую величину наклепанного слоя, определить конструкцию и геометрию концевых фрез для улучшения качества обработки стали 40Х. Тема диссертации актуальна для производства корпусов сборного инструмента на предприятии ООО "ПК МИОН".The object of research – end mills made of high-speed steel R6M5 with different angles of inclination of the screw chip groove in 20°, 30°, 45° and an end mill with a wavy cutting edge. The subject of the study is the influence on the size of the riveted layer after processing by milling steel 40X. Goal. Investigate the size of the riveted layer when processing 40X steel with high-speed steel end mills with different angles of inclination of the screw groove, identify a smaller size of the riveted layer, determine the design and geometry of the end mills to improve the quality of processing 40X steel. Relevance. The topic of the dissertation is relevant for the production of prefabricated tool cases at the company "PC MION"