An overview of 2-Styrylchromones: natural occurrence, synthesis, reactivity and biological properties

2-Styrylchromones are a small class of oxygen-containing heterocycles. Despite their sparse occurrence in nature, several synthetic approaches have been developed in order to synthesize a large variety of derivatives, possessing different substituents in different positions of the main core. They are also versatile building blocks in the synthesis of new heterocyclic systems and important intermediates in the search for bioactive compounds. It is our intention in this review to give a general overview on the natural occurrence, synthesis, reactivity and biological properties of 2-styrylchromones, which were published up until 2016.Thanks are due to the Instituto Politécnico de Bragança and also to the University of Aveiro and the Formación en Centros de Trabajo, Ministerio de Educación y Ciencia (FCT, MEC) for the financial support of the QOPNA research unit (FCT UID/QUI/ 00062/2013) through national funds and, where applicable, cofinanced by the Fundo Europeu De Desenvolvimento Regional (FEDER), within the PT2020 Partnership Agreement. Thanks are also due to the Portuguese NMR Network.info:eu-repo/semantics/publishedVersio