The emerging landscape of single-molecule protein sequencing technologies

Single-cell profiling methods have had a profound impact on the understanding of cellular heterogeneity. While genomes and transcriptomes can be explored at the single-cell level, single-cell profiling of proteomes is not yet established. Here we describe new single-molecule protein sequencing and identification technologies alongside innovations in mass spectrometry that will eventually enable broad sequence coverage in single-cell profiling. These technologies will in turn facilitate biological discovery and open new avenues for ultrasensitive disease diagnostics.This Perspective describes new single-molecule protein sequencing and identification technologies alongside innovations in mass spectrometry that will eventually enable broad sequence coverage in single-cell proteomics.</p

Vidéo Art Plastique : 9èmes Rencontres Hérouville Saint-Clair 1995

Works by 150 international artists are annotated in this catalogue which includes discussions about issues as diverse as current practices on the World Wide Web, process in television production, and video teaching in four European schools

Ars Electronica : Facing the Future : A Survey of Two Decades

A survey of the two decades of the Ars Electronica festival in Linz, Austria that draws on the resources of its publications and archives to represent the ongoing debate about the effects of digital media on creativity and culture. Three different sections address the history, theory and practice of electronic art. Co-founder H. Leopoldseder gives an overview of each year of the festival and its chosen theme from 1979 to1999. Biographical notes. 353 bibl. ref