36 research outputs found
Evaluation of upper limb sensitivity in patients with lymphedema after radical mastectomy
O objetivo deste trabalho foi avaliar a sensibilidade de membros superiores com linfedema pĂłs- mastectomia radical. Foram avaliadas nove pacientes, com mĂ©dia de idade de 60,7 anos, para verificar se ocorre diferença de sensibilidade entre o membro com linfedema e o membro sem linfedema. Para o teste de sensibilidade foram utilizados 6 monofilamentos de Semmens-Weinstes (modelo de bolso) “sensi kit”. As áreas testadas foram aquelas correspondentes aos dermátomos ligados Ă distribuição dos nervos ulnar, mediano e radial. Como resultados tivemos que o tempo decorrido desde a cirurgia foi em mĂ©dia de 8,9 anos, e o aparecimento do linfedema ocorreu em mĂ©dia 5,5 anos apĂłs a cirurgia. Utilizou-se a estatĂstica nĂŁo-paramĂ©trica, empregando-se o Teste de Fisher para pequenas amostras, das freqĂĽĂŞncias encontradas. Para cada lado testado evidenciou que a freqĂĽĂŞncia de pacientes que apresentaram sensibilidade no lado acometido foi significativamente menor (0,0045; p>0,005) do que a observada no lado controle, quando testado o Ponto 1, cor verde; nĂŁo houve diferenças estatisticamente importantes entre os lados avaliados nos demais pontos e cores testados; com relação ao grau de incapacidade, conforme o MinistĂ©rio da SaĂşde, nĂŁo houve qualquer diferença significativa entre os lados acometido e controle em qualquer dos sete pontos testados.The objective of this work was to evaluate the sensitivity of upper limbs with lymphoedema after radical mastectomy. Nine patients were evaluated, whose mean age was 60.7 years, to verify the presence of sensitivity difference between the limb with lymphedema and the control limb. For the sensitivity test, a six-monofilament Semmens-Weinstes "sensi kit" (pocket model) was used. The tested areas were those that corresponded to the dermatomes connected to the distribution of the ulnar, medianus and radialis nerves. Our results showed that the elapsed time since the surgery was on average 8.9 years and that the onset of lymphedema occurred on average 5.5 years after the surgery. Statistical analysis was non-parametrical and used Fisher's Test for small samples of the observed frequencies. For each tested side it was evidenced that the frequency of patients who presented sensitivity in the affected side was significantly smaller (0.0045; p>0.005) than the one observed in the control side, when Point 1, green color, was tested; there were no statistically significant differences between the evaluated sides in the remaining tested points and colors; regarding the incapacity degree, according to the Health Ministry, there were no significant differences between the affected and control sides in any of the seven tested points
Neuroplasticidade e estilo de vida: qual a relação?
RESUMO: Essa revisĂŁo teve como fundamento o gradativo rompimento do pensamento de que o cĂ©rebro Ă© um conjunto de multiestruturas isoladas permitiu a estruturação de um novo conceito: o cĂ©rebro Ă© um ĂłrgĂŁo dinâmico e adaptável frente Ă s exigĂŞncias impostas ao mesmo. Diante desse cenário, a neuroplasticidade ganha relevância, posto que, de acordo com C. H. Phelp (1990), trata-se de uma mudança adaptativa estrutural e funcional do sistema nervoso, que “ocorre em qualquer estágio da ontogenia, como função de interações com o ambiente interno ou externo ou, ainda, como resultado de injĂşrias, de traumatismos ou de lesões que afetam o ambiente neural”. Teve como objetivo revisar possĂveis associações entre neuroplasticidade e estilo de vida. Apresntou como metodologia a busca de livros e artigos, nacionais e internacionais, utilizando a Biblioteca Virtual em SaĂşde – BVS MS e o PubMed. Ultilizou-se como descritores: plasticidade neuronal, exercĂcios aerĂłbicos, yoga, e estilo de vida. 12 artigos foram selecionados e revisados, mas apenas 7 foram incluĂdos. Teve como resultados mais significativos encontradas referentes Ă estilo de vida, yoga e exercĂcios aerĂłbicos, ao lado da demonstração da relação entre neuroplasticidade e patologia de Alzheimer. Conclui-se que há relação entre neuroplasticidade e estilo de vida, porĂ©m, há diminuta amostragem de estudos sobre a temática. Ainda, os mecanismos que demonstram o vĂnculo descrito sĂŁo pouco compreendidos, inferindo e demandando maior volume de estudos esclarecedores sobre a temática.
 
Neuroplasticidade e estilo de vida: qual a relação? / Neuroplasticity and lifestyle: what is the relationship?
O gradativo rompimento do pensamento de que o cĂ©rebro Ă© um conjunto de multiestruturas isoladas permitiu a estruturação de um novo conceito: o cĂ©rebro Ă© um ĂłrgĂŁo dinâmico e adaptável frente Ă s exigĂŞncias impostas ao mesmo. Diante desse cenário, a neuroplasticidade ganha relevância, posto que, de acordo com C. H. Phelp (1990), trata-se de uma mudança adaptativa estrutural e funcional do sistema nervoso, que “ocorre em qualquer estágio da ontogenia, como função de interações com o ambiente interno ou externo ou, ainda, como resultado de injĂşrias, de traumatismos ou de lesões que afetam o ambiente neural”. Objetivo: Revisar possĂveis associações entre neuroplasticidade e estilo de vida. Metodologia: Foi realizado busca de livros e artigos, nacionais e internacionais, utilizando a Biblioteca Virtual em SaĂşde – BVS MS e o PubMed. Utilizou-se como descritores: plasticidade neuronal, exercĂcios aerĂłbicos, yoga, e estilo de vida. 12 artigos foram selecionados e revisados, mas apenas 7 foram incluĂdos. Resultados: Yoga e exercĂcios aerĂłbicos foram Ă s relações mais significativas encontradas referentes a estilo de vida, ao lado da demonstração da relação entre neuroplasticidade e patologia de Alzheimer. ConclusĂŁo: Há relação entre neuroplasticidade e estilo de vida, porĂ©m, há diminuta amostragem de estudos sobre a temática. Ainda, os mecanismos que demonstram o vĂnculo descrito sĂŁo pouco compreendidos, inferindo e demandando maior volume de estudos esclarecedores sobre a tematica
Analysis of the effects of the interruption of the flow in the normal arterial endothelium morphology and the correlation with the ischemia duration in rabbits
Critérios semiquantitativos de análise da linfocintilografia em linfedema dos membros inferiores
Health-related quality of life in patients with type 1 diabetes mellitus in the different geographical regions of Brazil : data from the Brazilian Type 1 Diabetes Study Group
Background: In type 1 diabetes mellitus (T1DM) management, enhancing health-related quality of life (HRQoL) is as important as good metabolic control and prevention of secondary complications. This study aims to evaluate possible regional differences in HRQoL, demographic features and clinical characteristics of patients with T1DM in Brazil, a country of continental proportions, as well as investigate which variables could influence the HRQoL of these individuals and contribute to these regional disparities. Methods: This was a retrospective, cross-sectional, multicenter study performed by the Brazilian Type 1 Diabetes Study Group (BrazDiab1SG), by analyzing EuroQol scores from 3005 participants with T1DM, in 28 public clinics, among all geographical regions of Brazil. Data on demography, economic status, chronic complications, glycemic control and lipid profile were also collected. Results: We have found that the North-Northeast region presents a higher index in the assessment of the overall health status (EQ-VAS) compared to the Southeast (74.6 ± 30 and 70.4 ± 19, respectively; p < 0.05). In addition, North- Northeast presented a lower frequency of self-reported anxiety-depression compared to all regions of the country (North-Northeast: 1.53 ± 0.6; Southeast: 1.65 ± 0.7; South: 1.72 ± 0.7; Midwest: 1.67 ± 0.7; p < 0.05). These findings could not be entirely explained by the HbA1c levels or the other variables examined. Conclusions: Our study points to the existence of additional factors not yet evaluated that could be determinant in the HRQoL of people with T1DM and contribute to these regional disparities
Pervasive gaps in Amazonian ecological research
Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4
While the increasing availability of global databases on ecological communities has advanced our knowledge
of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In
the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of
Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus
crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced
environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian
Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by
2050. This means that unless we take immediate action, we will not be able to establish their current status,
much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio
Health-related quality of life in patients with type 1 diabetes mellitus in the different geographical regions of Brazil: data from the Brazilian Type 1 Diabetes Study Group
Pervasive gaps in Amazonian ecological research
Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost