333 research outputs found

    The problem with teaching ‘British values’ in school

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    The piece will focus on what the mandatory promotion of British values in schools means for practice in schools, and for wider debates around democracy and citizenship, with particular reference to the social and political context of Brexit and anti-extremism policies

    A latent class analysis of parental bipolar disorder: examining associations with offspring psychopathology

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    Bipolar disorder (BD) is highly heterogeneous, and course variations are associated with patient outcomes. This diagnostic complexity challenges identification of patients in greatest need of intervention. Additionally, course variations have implications for offspring risk. First, latent class analysis (LCA) categorized parents with BD based on salient illness characteristics: BD type, onset age, polarity of index episode, pole of majority of episodes, rapid cycling, psychosis, anxiety comorbidity, and substance dependence. Fit indices favored three parental classes with some substantively meaningful patterns. Two classes, labeled “Earlier-Onset Bipolar-I” (EO-I) and “Earlier-Onset Bipolar-II” (EO-II), comprised parents who had a mean onset age in mid-adolescence, with EO-I primarily BD-I parents and EO-II entirely BD-II parents. The third class, labeled “Later-Onset BD” (LO) had an average onset age in adulthood. Classes also varied on probability of anxiety comorbidity, substance dependence, psychosis, rapid cycling, and pole of majority of episodes. Second, we examined rates of disorders in offspring (ages 4–33, Mage=13.46) based on parental latent class membership. Differences emerged for offspring anxiety disorders only such that offspring of EO-I and EO-II parents had higher rates, compared to offspring of LO parents, particularly for daughters. Findings may enhance understanding of BD and its nosologyThis study was funded by two Brain & Behavior Research Foundation (formerly NARSAD) Independent Investigator Awards (PI: Nierenberg), a Brain & Behavior Research Foundation Young Investigator Award (PI: Henin) generously supported in part by the SHINE Initiative, and an MGH Claflin Award (PI: Henin). We thank David A. Langer, Ph.D., Thomas M. Olino, Ph.D., and Meredith Lotz Wallace, Ph.D. for their consultation. (Brain & Behavior Research Foundation; Brain & Behavior Research Foundation Young Investigator Award; SHINE Initiative; MGH Claflin Award)Accepted manuscrip

    Conditions in the eastern equatorial Pacific related to the intertropical convergence zone of the winds. Qggp. gig _B_e

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    Abstract-Surface temperature and salinity data gathered by merchant ships along the TahitiPanama track from 1955 to 1978 are considered in relation t o cloud cover. Equatorial upwelling is associated with strong cloudiness at its northern boundary. The cloudiness indicates the presence of the intertropical convergence zone of the winds. During the seasonal absence of upwelling, the position of the intertropical convergence zone is southernmost and the cloudy zone is south of the equator. In the case of EI Niño, equatorial upwelling weakens, the northern cloud cover is minimal, and the intertropical convergence zone may shift southward. During EI Niño, the surface salinity is affected by the position of the intertropical convergence zone

    Implant surfaces exposed to the oral cavity and treated with toothpaste containing oxygen releasing compound : a morphological controlled clinical trial

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    Aim of the present in vivo study is to assess if a toothpaste containing an oxygen releasing compound (AX) is able to reduce the biofilm formation on implants with rough surface compared to a control toothpaste, without affecting the microstructure of the tested surface. Methods: In this double blind, cross-over, controlled clinical trial, a total of fourteen healthy volunteers were recruited. For each subject, two mandibular splints (test and control) were created with one implant fixed on the right lingual side of the mandibular arch. The splint was continuously worn for 5 days and the daily hygiene was performed wearing the splint and using the test (AX) or control toothpaste. Implants were analyzed at scanning-electron-microscopy and at laser profilometer for the assessment of biofilm adhesion (% of areas free from biofilm-FA) and surface changes (morphology and roughness). Results: FA resulted significantly higher in test than in control implants. No differences were found between groups in term of biofilm organization, surface microstructure and roughness. Discussion: Daily use of toothpaste containing AX seems to reduce the amount of biofilm adherent to the rough implant surface without corrosion or degradation of the titanium surface

    Engaging narratives evoke similar neural activity and lead to similar time perception

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    It is said that we lose track of time - that “time flies” - when we are engrossed in a story. How does engagement with the story cause this distorted perception of time, and what are its neural correlates? People commit both time and attentional resources to an engaging stimulus. For narrative videos, attentional engagement can be represented as the level of similarity between the electroencephalographic responses of different viewers. Here we show that this measure of neural engagement predicted the duration of time that viewers were willing to commit to narrative videos. Contrary to popular wisdom, engagement did not distort the average perception of time duration. Rather, more similar brain responses resulted in a more uniform perception of time across viewers. These findings suggest that by capturing the attention of an audience, narrative videos bring both neural processing and the subjective perception of time into synchrony

    Age and sex affect intersubject correlation of EEG throught development

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    Recent efforts have aimed to characterize clinical pediatric populations by using neurophysiological tests in addition to behavioral assays. Here we report on a data collection effort in which electroencephalography (EEG) was recorded in both juveniles and adults (N=114 participants, ages 6-44 years of age) during various stimulation protocols. The present analysis focuses on how neural responses during passive viewing of naturalistic videos vary with age and sex, and in particular, how similar they are within developmental groups. Similarity of neural responses was measured as the inter-subject correlation of the EEG. Stimulus-evoked neural responses are more similar among children and decrease in similarity with age. Among children, males respond more similarly to each other than females. This was uniformly true for a variety of videos. The decrease in group similarity with age may result from an overall decline in the magnitude of evoked responses, but this cannot explain the sex differences found in the young. We therefore propose that as children mature, neural function may become more variable

    The Variability of Neural Responses to Naturalistic Videos Change with Age and Sex

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    Neural development is generally marked by an increase in the efficiency and diversity of neural processes. In a large sample (n=114) of human children and adults with ages ranging from 5 to 44 yr, we investigated the neural responses to naturalistic video stimuli. Videos from both real-life classroom settings and Hollywood feature films were used to probe different aspects of attention and engagement. For all stimuli, older ages were marked by more variable neural responses. Variability was assessed by the intersubject correlation of evoked electroencephalographic responses. Young males also had less-variable responses than young females. These results were replicated in an independent cohort (n = 303). When interpreted in the context of neural maturation, we conclude that neural function becomes more variable with maturity, at least during the passive viewing of real-world stimuli.Fil: Petroni, AgustĂ­n. City University of New York; Estados Unidos. Consejo Nacional de Investigaciones CientĂ­ficas y TĂ©cnicas; ArgentinaFil: Cohen, Samantha S.. City University of New York; Estados UnidosFil: Ai, Lei. City University of New York; Estados UnidosFil: Langer, Nicolas. City University of New York; Estados UnidosFil: Henin, Simon. City University of New York; Estados UnidosFil: Vanderwal, Tamara. City University of New York; Estados UnidosFil: Milham, Michael P.. City University of New York; Estados UnidosFil: Parra, Lucas C.. City University of New York; Estados Unido

    Multijoule scaling of laser-induced condensation in air

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    Using 100 TW laser pulses, we demonstrate that laser-induced nanometric particle generation in air increases much faster than the beam-averaged incident intensity. This increase is due to a contribution from the photon bath, which adds up with the previously identified one from the filaments and becomes dominant above 550 GW/cm2. It appears related to ozone formation via multiphotondissociation of the oxygen molecules and demonstrates the critical need for further increasing the laser energy in view of macroscopic effects in laser-induced condensation

    On negative higher-order Kerr effect and filamentation

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    As a contribution to the ongoing controversy about the role of higher-order Kerr effect (HOKE) in laser filamentation, we first provide thorough details about the protocol that has been employed to infer the HOKE indices from the experiment. Next, we discuss potential sources of artifact in the experimental measurements of these terms and show that neither the value of the observed birefringence, nor its inversion, nor the intensity at which it is observed, appear to be flawed. Furthermore, we argue that, independently on our values, the principle of including HOKE is straightforward. Due to the different temporal and spectral dynamics, the respective efficiency of defocusing by the plasma and by the HOKE is expected to depend substantially on both incident wavelength and pulse duration. The discussion should therefore focus on defining the conditions where each filamentation regime dominates.Comment: 22 pages, 11 figures. Submitted to Laser physics as proceedings of the Laser Physics 2010 conferenc
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