82 research outputs found
The characteristics of juvenile myasthenia gravis among South Africans
OBJECTIVES: To report the characteristics of juvenile-onset (<20
years) myasthenia gravis (MG) in Africa.
SUBJECTS AND METHOD: Six South African centres collected data
which included acetylcholine receptor-antibody (AChR-ab) status,
delay before diagnosis, MG Foundation of America grade at onset,
maximum severity and severity at last visit, therapies, outcomes and
complications.
RESULTS: We report on 190 individuals with a 4-year median
follow-up (interquartile range (IQR) 1 - 8). The median age at
symptom onset was 7 years (IQR 4 - 14). Ocular MG (26%) occurred
among younger children (mean 5.1 years) compared with those
developing generalised MG (74%) (mean 10.2 years) (p=0.0004).
Remissions were obtained in 45% of generalised and 50% of ocular
MG patients, of whom the majority received immunosuppressive
treatment, mainly prednisone. Children with post-pubertal onset
had more severe MG, but deaths were infrequent.
Thymectomies were performed in 43% of those with generalised
MG who suffered greater maximum disease severity (p=0.002);
there was a trend towards more remissions in the thymectomy
group compared with the non-thymectomy group (p=0.057).
There was no racial variation with respect to AChR-ab status,
maximum severity, or use of immunosuppression. However, 23% of
children of African genetic ancestry developed partial or complete
ophthalmoplegia as a complication of generalised MG (p=0.002).
CONCLUSION: Younger children developed ocular MG and older
children generalised MG. Persistent ophthalmoplegia developing as
a MG complication is not uncommon among juveniles of African
genetic ancestry. A successful approach to the management of this
complication that causes significant morbidity is, as yet, unclear.http://www.samj.org.z
Semi-Analytic Stellar Structure in Scalar-Tensor Gravity
Precision tests of gravity can be used to constrain the properties of
hypothetical very light scalar fields, but these tests depend crucially on how
macroscopic astrophysical objects couple to the new scalar field. We develop
quasi-analytic methods for solving the equations of stellar structure using
scalar-tensor gravity, with the goal of seeing how stellar properties depend on
assumptions made about the scalar coupling at a microscopic level. We
illustrate these methods by applying them to Brans-Dicke scalars, and their
generalization in which the scalar-matter coupling is a weak function of the
scalar field. The four observable parameters that characterize the fields
external to a spherically symmetric star (the stellar radius, R, mass, M,
scalar `charge', Q, and the scalar's asymptotic value, phi_infty) are subject
to two relations because of the matching to the interior solution, generalizing
the usual mass-radius, M(R), relation of General Relativity. We identify how
these relations depend on the microscopic scalar couplings, agreeing with
earlier workers when comparisons are possible. Explicit analytical solutions
are obtained for the instructive toy model of constant-density stars, whose
properties we compare to more realistic equations of state for neutron star
models.Comment: 39 pages, 9 figure
Spin asymmetry A_1^d and the spin-dependent structure function g_1^d of the deuteron at low values of x and Q^2
We present a precise measurement of the deuteron longitudinal spin asymmetry
A_1^d and of the deuteron spin-dependent structure function g_1^d at Q^2 < 1
GeV^2 and 4*10^-5 < x < 2.5*10^-2 based on the data collected by the COMPASS
experiment at CERN during the years 2002 and 2003. The statistical precision is
tenfold better than that of the previous measurement in this region. The
measured A_1^d and g_1^d are found to be consistent with zero in the whole
range of x.Comment: 17 pages, 10 figure
The COMPASS Experiment at CERN
The COMPASS experiment makes use of the CERN SPS high-intensitymuon and
hadron beams for the investigation of the nucleon spin structure and the
spectroscopy of hadrons. One or more outgoing particles are detected in
coincidence with the incoming muon or hadron. A large polarized target inside a
superconducting solenoid is used for the measurements with the muon beam.
Outgoing particles are detected by a two-stage, large angle and large momentum
range spectrometer. The setup is built using several types of tracking
detectors, according to the expected incident rate, required space resolution
and the solid angle to be covered. Particle identification is achieved using a
RICH counter and both hadron and electromagnetic calorimeters. The setup has
been successfully operated from 2002 onwards using a muon beam. Data with a
hadron beam were also collected in 2004. This article describes the main
features and performances of the spectrometer in 2004; a short summary of the
2006 upgrade is also given.Comment: 84 papes, 74 figure
Collins and Sivers asymmetries for pions and kaons in muon-deuteron DIS
The measurements of the Collins and Sivers asymmetries of identified hadrons
produced in deep-inelastic scattering of 160 GeV/c muons on a transversely
polarised 6LiD target at COMPASS are presented. The results for charged pions
and charged and neutral kaons correspond to all data available, which were
collected from 2002 to 2004. For all final state particles both the Collins and
Sivers asymmetries turn out to be small, compatible with zero within the
statistical errors, in line with the previously published results for not
identified charged hadrons, and with the expected cancellation between the u-
and d-quark contributions.Comment: 16 pages, 9 figures, added author Efremov, calculated pure kaon
asymmetries instead of those for experimental kaon/pion mixture (mainly error
affected
Double spin asymmetry in exclusive rho^0 muoproduction at COMPASS
The longitudinal double spin asymmetry A_1^rho for exclusive leptoproduction
of rho^0 mesons, mu + N -> mu + N + rho, is studied using the COMPASS 2002 and
2003 data. The measured reaction is incoherent exclusive rho^0 production on
polarised deuterons. The Q^2 and x dependence of A_1^rho is presented in a wide
kinematical range: 3x10^-3 < Q^2 < 7 (GeV/c)^2 and 5x10^-5 < x < 0.05. The
presented results are the first measurements of A_1^rho at small Q2 (Q2 < 0.1
(GeV/c)^2) and small x (x < 3x10^-3). The asymmetry is in general compatible
with zero in the whole kinematical range.Comment: 6 Figures, 15 pages, version 2 with updated author list, technical
latex problem fixe
Observation of a sudden cessation of a very-high-energy gamma-ray flare in PKS 1510-089 with H.E.S.S. and MAGIC in May 2016
The flat spectrum radio quasar (FSRQ) PKS 1510-089 is known for its complex multiwavelength behavior, and is one of only a few FSRQs detected at very high energy (VHE, E >100 GeV) -rays. VHE -ray observations with H.E.S.S. and MAGIC during late May and early June 2016 resulted in the detection of an unprecedented flare, which reveals for the first time VHE -ray intranight variability in this source. While a common variability timescale of 1.5 hr is found, there is a significant deviation near the end of the flare with a timescale of ∼ 20 min marking the cessation of the event. The peak flux is nearly two orders of magnitude above the low-level emission. For the first time, curvature is detected in the VHE -ray spectrum of PKS 1510-089, which is fully explained through absorption by the extragalactic background light. Optical R-band observations with ATOM reveal a counterpart of the -ray flare, even though the detailed flux evolution differs from the VHE lightcurve. Interestingly, a steep flux decrease is observed at the same time as the cessation of the VHE flare. In the high energy (HE, E >100 MeV) -ray band only a moderate flux increase is observed with Fermi-LAT, while the HE -ray spectrum significantly hardens up to a photon index of 1.6. A search for broad-line region (BLR) absorption features in the -ray spectrum indicates that the emission region is located outside of the BLR. Radio VLBI observations reveal a fast moving knot interacting with a standing jet feature around the time of the flare. As the standing feature is located ∼ 50 pc from the black hole, the emission region of the flare may have been located at a significant distance from the black hole. If this correlation is indeed true, VHE rays have been produced far down the jet where turbulent plasma crosses a standing shock.Accepted manuscrip
Effect of fungal treatment of lignocellulosics on digestibility for ruminants
International audienc
Neutron stars and incompressible fluid spheres in the Jordan-Brans-Dicke theory of gravitation
Quasi-metrics and monotone normality
The purpose of this paper is to study which quasi-metrizable spaces are monotonically normal. In particular, we provide a sufficient condition for a quasi-metrizable space to be monotonically normal. This enables us to prove the monotone normality of a certain amount of interesting examples of quasi-metric spaces; for instance, we show that the continuous poset of formal balls of a metric space, endowed with the Scott topology, is a monotonically normal quasi-metrizable space. © 2011 Elsevier B.V.Gutiérrez García, J.; Romaguera Bonilla, S.; Sánchez Álvarez, JM. (2011). Quasi-metrics and monotone normality. Elsevier. doi:10.1016/j.topol.2011.06.046
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