Pavement Thickness Evaluation by GPR Survey in Idaho

In 1995 and 1996, the Idaho Transportation Department (lTD) conducted a series of ground-penetrating radar (GPR) surveys as a nondestructive testing (NDT) method to evaluate the thickness of asphalt and Portland cement concrete (AC/PCC) pavements in Idaho. GPR surveys employed both air-coupled and combination air and ground coupled systems with their associated equipment and software. A total of 30 miles of AC/PCC pavements were evaluated by GPR surveys. The results obtained were correlated with the site-specific ground-truth data from borings. Knowledge of pavement layer thickness is needed to predict pavement performance, establish load carrying capacities and develop maintenance and rehabilitation priorities. In addition, for new construction, it is important to ensure that the thickness of materials being placed by the contractor is acceptably close to specification. Core sampling and test pits are destructive to the pavement system, expensive, time consuming and intrusive to traffic. The objective of the lTD study was to evaluate, compare and assess the ability of these two GPR systems to accurately measure the thickness of multiple pavement layers, and document the data nondestructively. This paper reviews the findings of these surveys and provides statistically based data for both AC and PCC pavements. The overall study has shown that reasonably accurate, dependable determination of pavement thickness can be achieved by using GPR survey for conditions encountered in Idaho

Vulnerability of Water Supply Systems to Droughts

This summary completion report describes the project work completed in three areas: 1) the development and preliminary testing of drought severity and vulnerability indices, 2) the impacts of Utah\u27s 1977 drought, and 3) an operation comparison of stochastic streamflow models. The drought indices were evaluated for three municipal and three irrigation water supply systems in Utah. It was concluded that a continuous loss function to define the effects of water shortage would be more appropriate than the existing assumption that drought-related lossed occur suddenly at a certain degree of water shortage. Information on the impacts of Utah\u27s 1977 drought was collected by surveys of municipal and rural domestic systems, water users in Salt Lake County, and farmers, stockmen, ranchers, and irrigation company officials. Survey results were used to examine drought effects in different regions of the state and with respect to size of municipal supply systems. Despite severe restrictiosn placed on Salt Lake County water users most did not consider the experience an undue burden. The comparison of five stochastic streamflow models on four Utah streams lead to a preliminary model choice strategy which is based on the historical estimates of the lag-one autocorrelation and Hurst coefficients

Microbes, histology, blood analysis, enterotoxins, and cytokines: Findings from the ASERF Systemic Symptoms in Women-Biospecimen Analysis Study: Part 3

BACKGROUND: There has been an increasing need to acquire rigorous scientific data to answer the concerns of physicians, patients, and the FDA regarding the self-reported illness identified as breast implant illness (BII). There are no diagnostic tests or specific laboratory values to explain the reported systemic symptoms described by these patients. OBJECTIVES: The aim of this study was to determine if there are quantifiable laboratory findings that can be identified in blood, capsule tissue pathology, or microbes that differentiate women with systemic symptoms they attribute to their implants from 2 control groups. METHODS: A prospective blinded study enrolled 150 subjects into 3 cohorts: (A) women with systemic symptoms they attribute to implants who requested implant removal; (B) women with breast implants requesting removal or exchange who did not have symptoms attributed to implants; and (C) women undergoing cosmetic mastopexy who have never had any implanted medical device. Capsule tissue underwent detailed analysis and blood was sent from all 3 cohorts to evaluate for markers of inflammation. RESULTS: No significant histologic differences were identified between the cohorts, except there were more capsules with synovial metaplasia in the non-BII cohort. There was no statistical difference in thyroid-stimulating hormone, vitamin D levels, or complete blood count with differential between the cohorts. Next-generation sequencing revealed no statistically significant difference in positivity between Cohort A and B. Of the 12 cytokines measured, 3 cytokines, interleukin (IL)-17A, IL-13, and IL-22, were found to be significantly more often elevated in sera of subjects in Cohort A than in Cohorts B or C. The enterotoxin data demonstrated an elevation in immunoglobulin G (IgG) anti-Staphylococcus aureus enterotoxin A in Cohort A. There was no correlation between the presence of IgE or IgG anti-Staphylococcal antibody and a positive next-generation sequencing result. CONCLUSIONS: This study adds to the current literature by demonstrating few identifiable biomedical markers to explain the systemic symptoms self-reported by patients with BII

Superconducting Cosmc Strings and Primordial Magnetic Fields

We consider grand unified theories with superconducting cosmic strings and which admit the mechanism for generating primordial magnetic fields recently discussed by Vachaspati. We show that these models are severely constrained by cosmological arguments. Quite generically, either stable springs or vortons will form. Provided the mass per unit length of the strings is sufficiently large, these stable configurations will overclose the Universe.Comment: BROWN-HET-830, 14 pages, use phyzz

Reduced T2* Values in Soleus Muscle of Patients with Type 2 Diabetes Mellitus

Tissue water transverse relaxation times (T2) are highly sensitive to fluid and lipid accumulations in skeletal muscles whereas the related T2* is sensitive to changes in tissue oxygenation in addition to factors affecting T2. Diabetes mellitus (DM) affects muscles of lower extremities progressively by impairing blood flow at the macrovascular and microvascular levels. This study is to investigate whether T2 and T2* are sensitive enough to detect abnormalities in skeletal muscles of diabetic patients in the resting state. T2 and T2* values in calf muscle of 18 patients with type 2 DM (T2DM), 22 young healthy controls (YHC), and 7 age-matched older healthy controls (OHC) were measured at 3T using multi-TE spin echo and gradient echo sequences. Regional lipid levels of the soleus muscle were also measured using the Dixon method in a subset of the subjects. Correlations between T2, T2*, lipid levels, glycated hemoglobin (HbA1c) and presence of diabetes were evaluated. We found that T2 values were significantly higher in calf muscles of T2DM subjects, as were T2* values in anterior tibialis, and gastrocnemius muscles of T2DM participants. However, soleus T2* values of the T2DM subjects were significantly lower than those of the older, age-matched HC cohort $(22.9\pm 0.5 vs 26.7\pm 0.4 ms, p<0.01)$. The soleus T2* values in the T2DM cohort were inversely correlated with the presence of diabetes (t = −3.46, p<0.001) and with an increase in HbA1c, but not with body mass index or regional lipid levels. Although multiple factors may contribute to changes in T2* values, the lowered T2* value observed in the T2DM soleus muscle is most consistent with a combination of high oxygen consumption and poor regional perfusion. This finding is consistent with results of previous perfusion studies and suggests that the soleus in individuals with T2DM is likely under tissue oxygenation stress

Using participatory workshops to assess alignment or tension in the community for minimally invasive tissue sampling prior to start of child mortality surveillance: lessons From 5 sites across the CHAMPS network

The Child Health and Mortality Prevention Surveillance (CHAMPS) program is a 7-country network (as of December 2018) established by the Bill &amp; Melinda Gates Foundation to identify the causes of death in children in communities with high rates of under-5 mortality. The program carries out both mortality and pregnancy surveillance, and mortality surveillance employs minimally invasive tissue sampling (MITS) to gather small samples of body fluids and tissue from the bodies of children who have died. While this method will lead to greater knowledge of the specific causes of childhood mortality, the procedure is in tension with cultural and religious norms in many of the countries where CHAMPS works - Bangladesh, Ethiopia, Kenya, Mali, Mozambique, Sierra Leone, and South Africa. Participatory Inquiry Into Community Knowledge of Child Health and Mortality Prevention (PICK-CHAMP) is a community entry activity designed to introduce CHAMPS to communities and gather initial perspectives on alignments and tensions between CHAMPS activities and community perceptions and priorities. Participants' responses revealed medium levels of overall alignment in all sites (with the exception of South Africa, where alignment was high) and medium levels of tension (with the exception of Ethiopia, where tension was high). Alignment was high and tension was low for pregnancy surveillance across all sites, whereas Ethiopia reflected low alignment and high tension for MITS. Participants across all sites indicated that support for MITS was possible only if the procedure did not interfere with burial practices and rituals

MASSACHUSETTS WHIGS, 1833-1854.

Abstract not availabl

Race, Property Rights, and the Economic Consequences of Reconstruction: A Case Study

In assessing the problems of race and debtor relief in Mississippi during Reconstruction, it is clear that, on the local level, the Lafayette County court system, as represented by the Lafayette county court, effectively carried out an institutional framework established by the Mississippi legislature and the Mississippi Supreme Court in which the freedman was denied any meaningful role and/or opportunity in the economic environment of the community.In doing so, the county court system, by allegedly protecting the rights of private property, helped stifle the economic recovery of Lafayette County and, inferentially, the State as a whole. Moreover, by quickly acting in accordance with the Mississippi legislature\u27s and Mississippi Supreme Court\u27s initial actions regarding private debtor relief, the county court system in Lafayette actively contributed to sustaining an economic environment which not only slowed the pace of economic recovery, but also assured that the economic elite or private property owners of the local community sustained their power and influence over the course of future developments. In general, the Lafayette county court demonstrated that,on the local level, the judicial system could and did adjust to the demands of the national and state government while simultaneously satisfying and promoting its own constituency\u27s interests