325 research outputs found
Maternal protein-energy supplementation does not affect adolescent blood pressure in The Gambia.
BACKGROUND: Birthweight, and by inference maternal nutrition during pregnancy, is thought to be an important determinant of offspring blood pressure but the evidence base for this in humans is lacking data from randomized controlled trials. METHODS: The offspring from a maternal prenatal protein-energy supplementation trial were enrolled into a follow-up study of chronic disease risk factors including blood pressure. Subjects were 11-17 years of age and blood pressure was measured in triplicate using an automated monitor (Omron 705IT). One-thousand two-hundred sixty seven individuals (71% of potential participants) were included in the analysis. RESULTS: There was no difference in blood pressure between those whose mothers had consumed protein-energy biscuits during pregnancy and those whose mothers had consumed the same supplement post-partum. For systolic blood pressure the intention-to-treat regression coefficient was 0.46 (95% CI: -1.12, 2.04). Mean systolic blood pressure for control children was 110.2 (SD +/- 9.3) mmHg and for intervention children was 110.8 (SD +/- 8.8) mmHg. Mean diastolic blood pressure for control children was 64.7 (SD +/- 7.7) mmHg and for intervention children was 64.6 (SD +/- 7.6) mmHg. CONCLUSIONS: We have found no association between maternal prenatal protein-energy supplementation and offspring blood pressure in adolescence amongst rural Gambians. We found some evidence to suggest that offspring body composition may interact with the effect of maternal supplementation on blood pressure
Governance, Coordination and Evaluation: the case for an epistemological focus and a return to C.E. Lindblom
While much political science research focuses on conceptualizing and analyzing various forms of governance, there remains a need to develop frameworks and criteria for governance evaluation (Torfing et al 2012). The post-positivist turn, influential in recent governance theory, emphasizes the complexity, uncertainty and the contested normative dimensions of policy analysis. Yet a central evaluative question still arises concerning the capacity of governance networks to facilitate âcoordinationâ. The classic contributions of Charles Lindblom, although pre-dating the contemporary governance literature, can enable further elaboration of and engagement with this question. Lindblomâs conceptualisation of coordination challenges in the face of complexity shares with post-positivism a recognition of the inevitably contested nature of policy goals. Yet Lindblom suggests a closer focus on the complex, dynamically evolving, broadly âeconomicâ choices and trade-offs involved in defining and delivery policy for enabling these goals to be achieved and the significant epistemological challenges that they raise for policy-makers. This focus can complement and enrich both post-positivist scholarship and the process and incentives-orientated approaches which predominate in contemporary political science research on coordination in governance. This is briefly illustrated through a short case study evaluating governance for steering markets towards delivering low and zero carbon homes in England
The problem of gender categorisation: addressing dilemmas past and present in gender and education research
Developments in the field of gender theory as applied to education since the 1970s are briefly reviewed in order to highlight key challenges and debates around gender categorisation and identification in gender and education. We argue that conundrums of categorisation have haunted, and continue to haunt, the field of gender theory, and empirical applications (such as the case of education) in particular. We explain how we have attempted to address some of the conundrums arising in our own theoretical work, and analyse remaining challenges that we feel the field of education needs to address in order to advance theoretically. Identifying two key tensions underpinning this empirical dilemma of gender categorisation â the tension between agency and determinism in gender identification, and that between gender deconstruction and gender analysis â we seek to weave a path through some of these complex debates, and to indicate ways in which they may be addressed in future work. We argue that in order to avoid essentialism and reification of gender distinction, we need to apply a âthree-foldâ analysis that incorporates three different elements in our categorisation of gender: spectator perspective; respondent perspective and social context
Fore-arc deformation and underplating at the northern Hikurangi margin, New Zealand
Geophysical investigations of the northern Hikurangi subduction zone northeast of New Zealand, image foreâarc and surrounding upper lithospheric structures. A seismic velocity (Vp) field is determined from seismic wideâangle data, and our structural interpretation is supported by multichannel seismic reflection stratigraphy and gravity and magnetic modeling. We found that the subducting Hikurangi Plateau carries about 2 km of sediments above a 2 km mixed layer of volcaniclastics, limestone, and chert. The upper plateau crust is characterized by Vp = 4.9â6.7 km/s overlying the lower crust with Vp > 7.1 km/s. Gravity modeling yields a plateau thickness around 10 km. The reactivated Raukumara foreâarc basin is >10 km deep, deposited on 5â10 km thick Australian crust. The foreâarc mantle of Vp > 8 km/s appears unaffected by subduction hydration processes. The East Cape Ridge foreâarc high is underlain by a 3.5 km deep strongly magnetic (3.3 A/m) highâvelocity zone, interpreted as part of the onshore Matakaoa volcanic allochthon and/or uplifted Raukumara Basin basement of probable oceanic crustal origin. Beneath the trench slope, we interpret lowâseismicâvelocity, highâattenuation, lowâdensity foreâarc material as accreted and recycled, suggesting that underplating and uplift destabilizes East Cape Ridge, triggering twoâsided mass wasting. Mass balance calculations indicate that the proposed accreted and recycled material represents 25â100% of all incoming sediment, and any remainder could be accounted for through erosion of older accreted material into surrounding basins. We suggest that continental mass flux into the mantle at subduction zones may be significantly overestimated because crustal underplating beneath foreâarc highs have not properly been accounted for
Combined U-Pb and Lu-Hf isotope analyses by laser ablation MC-ICP-MS : methodology and applications
O sistema isotĂłpico LutĂ©cio-Hafnio representa uma das ferramentas mais recentes e poderosas para estudos isotĂłpicos e geocronolĂłgicos. AnĂĄlises combinadas in situ de U-Pb e Lu-Hf sobre zircĂŁo pelo LA-MC-ICP-MS permitem caracterizar isotopicamente o magma onde ele cristalizou, fornecendo valiosas informaçÔes para estudos de proveniĂȘncia de sedimento e de evolução crustal. Nesse trabalho descrevemos a sistemĂĄtica de Lu-Hf pelo LA-MC-ICP-MS implantada no laboratĂłrio de Geocronologia da Universidade de BrasĂlia e reportamos os resultados obtidos de repetidas anĂĄlises de trĂȘs padrĂ”es de zircĂŁo: GJ-1 = 0.282022 ± 11 (2SD, n=56), Temora 2 = 0.282693 ± 14 (2SD, n=25) and UQ-Z = 0.282127 ± 33 (2SD, n=11). Foi tambĂ©m caracterizada arazĂŁo isotĂłpica 176Hf/177Hf(0.282352 ± 22, 2SD, n=14) de um zircĂŁo usado como padrĂŁo interno do laboratĂłrio. Como aplicação geolĂłgica, analisamos dois zircĂ”es complexos selecionados a partir de uma amostra de migmatito da ProvĂncia de Borborema, NE do Brasil. Sobre a base dos dados U-Pb e Lu-Hf foram identificados em ambos os zircĂ”es dois eventos de cristalização. Um evento mais antigo de 2.05 Ga nos nĂșcleos herdados, representa um evento magmĂĄtico Paleoproterozoico bem conhecido na ProvĂncia Borborema. Um segundo evento de ~ 575 Ma, reconhecido nas bordas, representa um evento magmĂĄtico-metamĂłrfico NeoproterozĂłico (Brasiliano). ________________________________________________________________________________________ ABSTRACTThe Lutetium-Hafnium isotopic system represents one of the most innovative and powerful tools for geochronology and isotopic studies. Combined U-Pb and Lu-Hf in situ analyses on zircon by LA-MC-ICP-MS permit to characterize isotopically the host magma from which it crystallized furnishing significant information for sediment provenance and crustal evolution studies. In this paper e describe the Lu-Hf systematic by LA-MC-ICP-MS developed in the laboratory of Geochronology of the University of Brasilia and report the results obtained by repeated analyses of 176Hf/177Hf isotopic ratio of three zircon standards: GJ-1 = 0.282022 ± 11 (n=56), Temora 2 = 0.282693 ± 14 (n=25) and UQZ = 0.282127 ± 33 (n=11). The 176Hf/177Hf ratio (0.282352 ± 22, n=14) of gem quality zircon used as in-house standard have been also characterized. As a geological application, we analyzed two complex zircons selected from a migmatitic rocks from the Borborema Province, NE Brazil. On the basis of U-Pb and Lu-Hf data, two main crystallization events have been identified in both studied zircons. An older event at ca. 2.05 Ga recognized in the inherited cores represents a well-characterized paleoproterozoic magmatic event that affected the whole Borborema Province. A second crystallization event at ~ 575 Ma, recognized at the rims, represents a Neoproterozoic (Brazilian) high grade metamorphic-magmatic event
A qualitative investigation into the impact of domestic abuse on womenâs desistance
While criminological literature, criminal justice practice, and to a lesser extent, state policy have acknowledged a link between womenâs criminalisation and gendered violence (MoJ, 2018; Ăsterman, 2018; Prison Reform Trust, 2017; Roberts, 2015), there has been much less acknowledgement of the role of historical and contemporaneous experiences of violence in the desistance scripts of criminalised women. Combining findings from two research projects exploring gender and desistance, this article argues that (i) criminalised womenâs experiences of gendered violence are such that any exploration of gender and desistance which does not acknowledge this is incomplete, (ii) coercion and control can inform womenâs entry into the criminal justice system, (iii) expressions of agency and resistance in abusive interpersonal relationships can also inform womenâs offending, yet (iv) womenâs experiences of desistance from crime can mask the harm they face in coercive, controlling, and violent relationships. Thus, the article argues for a reframing of desistance from crime as desistance from harm both theoretically and in practice, and considers what this might entail
Seismic and geochemical evidence for large-scale mantle upwelling beneath the eastern Atlantic and western and central Europe
Seismic tomography and the isotope geochemistry of Cenozoic volcanic rocks suggest the existence of a large, sheet-like region of upwelling in the upper mantle which extends from the eastern Atlantic Ocean to central Europe and the western Mediterranean. A belt of extension and rifting in the latter two areas appears to lie above the intersection of the centre of the upwelling region with the base of the lithosphere. Lead, strontium and neodymium isotope data for all three regions converge on a restricted composition, inferred to be that of the upwelling mantle
The History, Relevance, and Applications of the Periodic System in Geochemistry
Geochemistry is a discipline in the earth sciences concerned with understanding the chemistry of the Earth and what that chemistry tells us about the processes that control the formation and evolution of Earth materials and the planet itself. The periodic table and the periodic system, as developed by Mendeleev and others in the nineteenth century, are as important in geochemistry as in other areas of chemistry. In fact, systemisation of the myriad of observations that geochemists make is perhaps even more important in this branch of chemistry, given the huge variability in the nature of Earth materials â from the Fe-rich core, through the silicate-dominated mantle and crust, to the volatile-rich ocean and atmosphere. This systemisation started in the eighteenth century, when geochemistry did not yet exist as a separate pursuit in itself. Mineralogy, one of the disciplines that eventually became geochemistry, was central to the discovery of the elements, and nineteenth-century mineralogists played a key role in this endeavour. Early âgeochemistsâ continued this systemisation effort into the twentieth century, particularly highlighted in the career of V.M. Goldschmidt. The focus of the modern discipline of geochemistry has moved well beyond classification, in order to invert the information held in the properties of elements across the periodic table and their distribution across Earth and planetary materials, to learn about the physicochemical processes that shaped the Earth and other planets, on all scales. We illustrate this approach with key examples, those rooted in the patterns inherent in the periodic law as well as those that exploit concepts that only became familiar after Mendeleev, such as stable and radiogenic isotopes
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