Eğitim Kurumu Kaynakları, Aile Özellikleri ve Öğrenci Başarısı: Türkiye’den Ortaöğretim Kurumları Öğrenci Seçme Sınavı Örneği

The paper examines the determinants of student achievement on the secondary school entrance exam (SSEE). The data for this project were collected through a survey of 810 primaryschool graduates. The empirical work is carried out by forming a model on student achievement and three categories of school, student, and family characteristics from primary-school graduates who were successful in SSEE.Bu çalışmanın amacı, Ortaöğretim Kurumları Öğrenci Seçme Sınavı’na (OKS) katılan öğrencilerin başarısının hangi faktörlerden kaynaklandığını araştırmaktır. Veriler 810 ilkeğitim mezunuyla yapılan anket çalışması sonucu elde edilmiştir. Bu bilgilerden yararlanarak OKS’de yüksek puan alan ilkeğitim kurumu mezunlarının başarısı ile eğitim kurumu, öğrencinin ve ailenin nitelikleri arasındaki ilişki ortaya konulmaya çalışılmıştır

Comparison of Effects of Smoking and Smokeless Tobacco “Maras Powder” Use on Humoral Immune System Parameters

Background. The aim of this study is to assess the impacts of “Maras powder” and cigarette smoking on the parameters of the humoral immune system. Material and Methods. One hundred seventy seven subjects were included in the study. The IgA, IgG, IgM, C3 and C4 levels were detected via nephelometric method. Results. In 1.4% of the control group IgM levels were below normal where it was 10.8% and 18.6% in Maras powder group and in cigarette smoking group respectively. The IgM levels of both groups were significantly lower compared to the control group (P < .05). Nonetheless, the IgE levels of Maras powder group and smoking group were found to be remarkably higher compared to the control group (P < .01). Conclusion. Effects of Maras powder on humoral immune response were found to be similar to that of smoking

Salt tolerance in Solanum pennellii: antioxidant response and related QTL

<p>Abstract</p> <p>Background</p> <p>Excessive soil salinity is an important problem for agriculture, however, salt tolerance is a complex trait that is not easily bred into plants. Exposure of cultivated tomato to salt stress has been reported to result in increased antioxidant content and activity. Salt tolerance of the related wild species, <it>Solanum pennellii</it>, has also been associated with similar changes in antioxidants. In this work, <it>S. lycopersicum </it>M82, <it>S. pennellii </it>LA716 and a <it>S. pennellii </it>introgression line (IL) population were evaluated for growth and their levels of antioxidant activity (total water-soluble antioxidant activity), major antioxidant compounds (phenolic and flavonoid contents) and antioxidant enzyme activities (superoxide dismutase, catalase, ascorbate peroxidase and peroxidase) under both control and salt stress (150 mM NaCl) conditions. These data were then used to identify quantitative trait loci (QTL) responsible for controlling the antioxidant parameters under both stress and nonstress conditions.</p> <p>Results</p> <p>Under control conditions, cultivated tomato had higher levels of all antioxidants (except superoxide dismutase) than <it>S. pennellii</it>. However, under salt stress, the wild species showed greater induction of all antioxidants except peroxidase. The ILs showed diverse responses to salinity and proved very useful for the identification of QTL. Thus, 125 loci for antioxidant content under control and salt conditions were detected. Eleven of the total antioxidant activity and phenolic content QTL matched loci identified in an independent study using the same population, thereby reinforcing the validity of the loci. In addition, the growth responses of the ILs were evaluated to identify lines with favorable growth and antioxidant profiles.</p> <p>Conclusions</p> <p>Plants have a complex antioxidant response when placed under salt stress. Some loci control antioxidant content under all conditions while others are responsible for antioxidant content only under saline or nonsaline conditions. The localization of QTL for these traits and the identification of lines with specific antioxidant and growth responses may be useful for breeding potentially salt tolerant tomato cultivars having higher antioxidant levels under nonstress and salt stress conditions.</p

Dichloridobis[5-nitro-1-trimethyl­silyl­methyl-1H-benzimidazole-κN 3]cobalt(II) N,N-dimethyl­formamide solvate

The title compound, [CoCl2(C11H15N3O2Si)2]·C3H7NO, was synthesized from 5-nitro-1-trimethyl­silylmethyl-1H-benzimid­azole and cobalt(II) chloride in dimethyl­formamide. The CoII atom is coordinated in a distorted tetra­hedral environment by two Cl atoms and two N atoms. In the crystal structure, there are a number of C—H⋯Cl and C—H⋯O hydrogen-bonding inter­actions between symmetry-related mol­ecules

SELENIUM SUPPLEMENT AND CYS/MET INDEX IN TARM 92 BARLEY CULTIVAR

Selenium (Se) as essential micronutrient found in foods in the form of organic selenomethionine (SeMet) and selenocysteine (SeCys) in adequate amounts. However, selenite (SeO3 2-) or selenate (SeO4 2-) can be found in inorganic form in very low amounts. Higher plants indicate considerable variations in terms of Se requirement with various effects on plant metabolism and uptake of some nutrients. Barley (Hordeum vulgare L.) is a significant dietary source for this element for humans and animals. In present study, Cys/Met index of Tarm 92 registered barley cultivar subjected to increasing sodium selenate (Na2SeO4) doses (6.25, 12.50, 18.75, 25.00 g ha-1) was investigated. Amino acids were analyzed according to Ion Exchange Liquid Chromatography method by Amino Acid Analyzer AAA 339 M. The experimental soil was analyzed for texture, organic matter, pH, available Phosphorus (P), Nitrogen (N), and Potassium (K). The average Sulfur (S) level in Tarm 92 cultivar was 0.0514 mg 100mg-1. Results revealed significant effects of Se-treatments on grain Cys/Met index at 12.50 g ha-1. Average Cys/Met index remarkably increased to highest level at 12.50 g ha-1. However, at 25 g ha-1, the level (6.98 mg 100mg-1) was closer to that in control (5.10 mg 100mg-1) group. It was concluded in present study that 12.5 g ha-1 selenium treatment was sufficient to increase grain Cys/Met index of Tarm 92 barley cultiva

Comparison of the effects of intranasal and transdermal estradiol plus dydrogestorone on lipids, lipoprotein(a) and apolipoproteins in postmenopausal women

Amaç: Bu araştırmanın amacı, postmenopozal kadınlarda, intranazal ve transdermal 17 östradiol ile didrogesteronun kombine kesintisiz hormon replasman tedavisinin, serumlipid, lipoprotein(a) ve apolipoprotein düzeyleri üzerindeki etkilerini karşılaştırmaktır. Gereç ve Yöntem: Bu prospektif araştırmaya yaşları 43-54 arasında değişen, sağlıklı 50 postmenopozal kadın dahil edildi. Olgular, 12 hafta süre ile 300 μg/g ün intranazal 17 β- östradiol (n=25) veya 50 μg/gün transdermal östradiol (n=25) almak üzere iki gruba randomize edildi. Bütün olgulara 10 mg/gün oral didrogesteron kesintisiz verildi. Araştırmanın başında ve sonunda, total kolesterol, trigliserid, HDL, LDL, VLDL, lipoprotein(a), Apo A-I ve Apo B düzeyleri, grup içi ve gruplar arasında farkın yüzdeleri karşılaştırıldı. İstatistiksel analiz içinMann-WhitneyUveWilcoxontesti kullanıldı. P<0,05anlamlı kabul edildi. Bulgular: Araştırmayı, intranazal grubunda 16, transdermal gurubunda 18 olmak üzere 34 olgu tamamladı. İntranazal östradiol grubunda, tedavi başlangıcına kıyasla, tedavi sonunda sadece apolipoprotein B düzeyinde anlamlı bir azalma izlenirken (2,0±0,4'den 0,9±0,1'ye, p=0,028), total kolesterol, trigliserid, HDL, LDL,VLDL, lipoprotein(a) ve Apo A-I düzeylerinde anlamlı değişiklik izlenmedi. Transdermal östradiol gurubunda hiçbir değişkende anlamlı değişiklik gözlenmedi. Her iki grup arasında, tüm değişkenler açısından anlamlı farklılık yoktu. Sonuç: İntranazal ve transdermal östradiolün, didrogesteron kombinasyonuyla yapılan kesintisiz hormon replasman tedavisinin, total kolesterol, trigliserid, HDL, LDL, VLDL, lipoprotein(a) ve Apo A-I düzeylerine etkileri benzerdir.Objective: To compare the effects of continuous hormon replacement therapy in the form of intranasal and transdermal 17β-estradiol combined with dydrogesterone on serum lipids, lipoprotein(a) and apolipoproteins among postmenopausal women. Materials and methods: In this prospective study, 50 healthy postmenopausal women aged 43-54 years were randomly assigned to receive either 300 μg/day intranasal 17β- estradiol (n=25) or 50 μg/day transdermal 17β- estradiol (n=25) for 12 weeks. All women also received 10 mg/day oral dydrogesterone continuously. At the end of the study, changes in serum total cholesterol, triglyceride, HDL, LDL, VLDL, lipoprotein(a), Apo A-I and Apo B levels within and percent changes between the groups were compared. Mann-Whitney U and Wilcoxon tests were used as indicated. P-values below 0.05 were considered significant. Results: Thirty-four women completed this study (intranasal group, n=16; transdermal group, n=18). In intranasal estradiol group, only apolipoprotein B levels were decreased significantly after 12 weeks of treatment (2.0±0.4 to 0.9±0.1, p=0.028) whereas no changes in the levels of total cholesterol, triglyceride, HDL, LDL, VLDL, lipoprotein(a) and Apo A-I were observed. Also, in transdermal estradiol group, no significant changes were seen in all variables. No significant differences with regard to variables were noted between the groups at the end of the study. Conclusions: The effects of intranasal and transdermal estradiol plus dydrogestorone asa continouos hormone replacement therapy on the serum total cholesterol, triglyceride, HDL, LDL, VLDL, lipoprotein(a) and Apo A-I levels are similar in postmenopausal women

Phenological, Pomological and Technological Characteristics of Seedless White Mulberry in Mulberry Genetic Resources of Turkey

This study carried out in 2015 and 2016 to determine phenological, pomological and some technological characteristics of 19 seedless mulberry genotypes of the Malatya Apricot Research Institute. Full-bloom periods of the genotypes varied between 27th of April (Poser 24-07) and 3rd of May (24 MRK 02); start of harvest dates varied between 15th of May (Poser 24-07) and 31st of May (Yediveren 24-08); end of harvest dates varied between 5th of July (Angut 009) and 30th of August (Yediveren 24-08). Fruiting durations varied between 50 days (Angut 009) and 95 days (Gemirgap Dutu 24-05). Of the pomological characteristics, average fruit weights varied between 0.77 g (Angut 009) and 2.46 g (Poser 24-07); water soluble dry matter (WSDM) contents varied between 15.50% (Topu Beyaz 1) and 29.60% (Angut 009). Of the technological characteristics, drying efficiency values varied between 15.79% (44 KE 10) and 39.94% (Angut 009), dry fruit color L values varied between 25.97 (Poser 24-07) and 50.20 (İstanbul Dutu 24-12). Based on present findings, Poser 24-07 genotype was found to be prominent with early fruiting and availability for fresh consumption; Yediveren 24-08 genotype with late fruiting; İstanbul Dutu 24-12 genotype with drying efficiency and Gemirgap Dutu 24-05 and Gemirgap Dutu 24-06 genotypes with their longer fruiting durations. Current findings may be beneficial in mulberry breeding programs

Yakınları ve ailesi Çetin Emeç'i anlattı

Taha Toros Arşivi, Dosya No: 44-Çetin-Aydın-Ragıp Eme

Crizotinib efficacy and safety in patients with advanced NSCLC harboring MET alterations: A real-life data of Turkish Oncology Group

Crizotinib is a multikinase inhibitor, effective in non-small cell lung cancer (NSCLC) harboring mesenchymal-epidermal transition (MET) alterations. Although small prospective studies showed efficacy and safety of crizotinib in NSCLC with MET alterations, there is limited real-life data. Aim of this study is to investigate real-life efficacy and safety of crizotinib in patients with advanced NSCLC harboring MET alterations. This was a retrospective, multicenter (17 centers) study of Turkish Oncology Group. Patients' demographic, histological data, treatment, response rates, survival outcomes, and toxicity data were collected. Outcomes were presented for the study population and compared between MET alteration types. Total of 62 patients were included with a median age of 58.5 (range, 26-78). Major histological type was adenocarcinoma, and 3 patients (4.8%) had sarcomatoid component. The most common MET analyzing method was next generation sequencing (90.3%). MET amplification and mutation frequencies were 53.2% (n = 33) and 46.8% (n = 29), respectively. Overall response rate and disease control rate were 56.5% and 74.2% in whole study population, respectively. Median progression free survival (PFS) was 7.2 months (95% confidence interval [CI]: 3.8-10.5), and median overall survival (OS) was 18.7 months (95% CI: 13.7-23.7), regardless of treatment line. Median PFS was 6.1 months (95% CI: 5.6-6.4) for patients with MET amplification, whereas 14.3 months (95% CI: 6.7-21.7) for patients with MET mutation (P = .217). Median PFS was significantly longer in patients who have never smoked (P = .040), have good performance score (P < .001), and responded to the treatment (P < .001). OS was significantly longer in patients with MET mutation (25.6 months, 95% CI: 15.9-35.3) compared to the patients with MET amplification (11.0 months; 95% CI: 5.2-16.8) (P = .049). In never-smokers, median OS was longer than smoker patients (25.6 months [95% CI: 11.8-39.3] vs 16.5 months [95% CI: 9.3-23.6]; P = .049). The most common adverse effects were fatigue (50%), peripheral edema (21%), nausea (29%) and diarrhea (19.4%). Grade 3 or 4 adverse effects were observed in 6.5% of the patients. This real-life data confirms efficacy and safety of crizotinib in the treatment of advanced NSCLC harboring MET alteration