3,623 research outputs found

    The pre-main sequence binary HK Ori : Spectro-astrometry and EXPORT data

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    In this paper we present multi-epoch observations of the pre-main sequence binary HK Ori. These data have been drawn from the EXPORT database and are complemented by high quality spectro-astrometric data of the system. The spectroscopic data appear to be very well represented by a combination of an A dwarf star spectrum superposed on a (sub-)giant G-type spectrum. The radial velocity of the system is consistent with previous determinations, and does not reveal binary motion, as expected for a wide binary. The spectral, photometric and polarimetric properties and variability of the system indicate that the active object in the system is a T Tauri star with UX Ori characteristics. The spectro-astrometry of HK Ori is sensitive down to milli-arcsecond scales and confirms the speckle interferometric results from Leinert et al. The spectro-astrometry allows with fair certainty the identification of the active star within the binary, which we suggest to be a G-type T Tauri star based on its spectral characteristics.Comment: MNRAS in press 8 pages 7 figure

    Long-term health status and trajectories of seriously injured patients: A population-based longitudinal study

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    Improved understanding of the quality of survival of patients is crucial in evaluating trauma care, understanding recovery patterns and timeframes, and informing healthcare, social, and disability service provision. We aimed to describe the longer-term health status of seriously injured patients, identify predictors of outcome, and establish recovery trajectories by population characteristics.A population-based, prospective cohort study using the Victorian State Trauma Registry (VSTR) was undertaken. We followed up 2,757 adult patients, injured between July 2011 and June 2012, through deaths registry linkage and telephone interview at 6-, 12-, 24-, and 36-months postinjury. The 3-level EuroQol 5 dimensions questionnaire (EQ-5D-3L) was collected, and mixed-effects regression modelling was used to identify predictors of outcome, and recovery trajectories, for the EQ-5D-3L items and summary score. Mean (SD) age of participants was 50.8 (21.6) years, and 72% were male. Twelve percent (n = 333) died during their hospital stay, 8.1% (n = 222) of patients died postdischarge, and 155 (7.0%) were known to have survived to 36-months postinjury but were lost to follow-up at all time points. The prevalence of reporting problems at 36-months postinjury was 37% for mobility, 21% for self-care, 47% for usual activities, 50% for pain/discomfort, and 41% for anxiety/depression. Continued improvement to 36-months postinjury was only present for the usual activities item; the adjusted relative risk (ARR) of reporting problems decreased from 6 to 12 (ARR 0.87, 95% CI: 0.83-0.90), 12 to 24 (ARR 0.94, 95% CI: 0.90-0.98), and 24 to 36 months (ARR 0.95, 95% CI: 0.95-0.99). The risk of reporting problems with pain or discomfort increased from 24- to 36-months postinjury (ARR 1.06, 95% CI: 1.01, 1.12). While loss to follow-up was low, there was responder bias with patients injured in intentional events, younger, and less seriously injured patients less likely to participate; therefore, these patient subgroups were underrepresented in the study findings.The prevalence of ongoing problems at 3-years postinjury is high, confirming that serious injury is frequently a chronic disorder. These findings have implications for trauma system design. Investment in interventions to reduce the longer-term impact of injuries is needed, and greater investment in primary prevention is needed

    Using Cepheids to determine the galactic abundance gradient I. The solar neighbourhood

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    A number of studies of abundance gradients in the galactic disk have been performed in recent years. The results obtained are rather disparate: from no detectable gradient to a rather significant slope of about -0.1 dex kpc -1. The present study concerns the abundance gradient based on the spectroscopic analysis of a sample of classical Cepheids. These stars enable one to obtain reliable abundances of a variety of chemical elements. Additionally, they have well determined distances which allow an accurate determination of abundance distributions in the galactic disc. Using 236 high resolution spectra of 77 galactic Cepheids, the radial elemental distribution in the galactic disc between galactocentric distances in the range 6-11 kpc has been investigated. Gradients for 25 chemical elements (from carbon to gadolinium) are derived...Comment: 28 pages, 14 postscript figures, LaTeX, uses Astronomy and Astrophysics macro aa.cls, graphicx package, to be published in Astronomy and Astrophysics (2002) also available at http://www.iagusp.usp.br/~maciel/index.htm

    Dynamics of the circumstellar gas in the Herbig Ae stars BF Orionis, SV Cephei, WW Vulpeculae and XY Persei

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    We present high resolution (lambda / Delta_lambda = 49000) echelle spectra of the intermediate mass, pre-main sequence stars BF Ori, SV Cep, WW Wul and XY Per. The spectra cover the range 3800-5900 angstroms and monitor the stars on time scales of months and days. All spectra show a large number of Balmer and metallic lines with variable blueshifted and redshifted absorption features superimposed to the photospheric stellar spectra. Synthetic Kurucz models are used to estimate rotational velocities, effective temperatures and gravities of the stars. The best photospheric models are subtracted from each observed spectrum to determine the variable absorption features due to the circumstellar gas; those features are characterized in terms of their velocity, v, dispersion velocity, Delta v, and residual absorption, R_max. The absorption components detected in each spectrum can be grouped by their similar radial velocities and are interpreted as the signature of the dynamical evolution of gaseous clumps with, in most cases, solar-like chemical composition. This infalling and outflowing gas has similar properties to the circumstellar gas observed in UX Ori, emphasizing the need for detailed theoretical models, probably in the framework of the magnetospheric accretion scenario, to understand the complex environment in Herbig Ae (HAe) stars. WW Vul is unusual because, in addition to infalling and outflowing gas with properties similar to those observed in the other stars, it shows also transient absorption features in metallic lines with no obvious counterparts in the hydrogen lines. This could, in principle, suggest the presence of CS gas clouds with enhanced metallicity around WW Vul. The existence of such a metal-rich gas component, however, needs to be confirmed by further observations and a more quantitative analysis.Comment: 21 pages, 13 figures. Accepted for publication by Astronomy & Astrophysic

    EXPORT: optical photometry and polarimetry of Vega-type and pre-main sequence stars

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    This paper presents optical UBVRI broadband photo-polarimetry of the EXPORT sample obtained at the 2.5m Nordic Optical Telescope. The database consists of multi-epoch photo-polarimetry of 68 pre-main-sequence and main-sequence stars. An investigation of the polarization variability indicates that 22 objects are variable at the 3sigma level in our data. All these objects are pre-main sequence stars, consisting of both T Tauri and Herbig Ae/Be objects while the main sequence, Vega type and post-T Tauri type objects are not variable. The polarization properties of the variable sources are mostly indicative of the UXOR-type behaviour; the objects show highest polarization when the brightness is at minimum. We add seven new objects to the class of UXOR variables (BH Cep, VX Cas, DK Tau, HK Ori, LkHa 234, KK Oph and RY Ori). The main reason for their discovery is the fact that our data-set is the largest in its kind, indicating that many more young UXOR-type pre-main sequence stars remain to be discovered. The set of Vega-like systems has been investigated for the presence of intrinsic polarization. As they lack variability, this was done using indirect methods, and apart from the known case of BD +31.643, the following stars were found to be strong candidates to exhibit polarization due to the presence of circumstellar disks: 51 Oph, BD +31.643C, HD 58647 and HD 233517.Comment: A&A accepte

    Discrimination of Methionine Sulfoxide and Sulfone by Human Neutrophil Elastase

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    Human neutrophil elastase (HNE) is a uniquely destructive serine protease with the ability to unleash a wave of proteolytic activity by destroying the inhibitors of other proteases. Although this phenomenon forms an important part of the innate immune response to invading pathogens, it is responsible for the collateral host tissue damage observed in chronic conditions such as chronic obstructive pulmonary disease (COPD), and in more acute disorders such as the lung injuries associated with COVID-19 infection. Previously, a combinatorially selected activity-based probe revealed an unexpected substrate preference for oxidised methionine, which suggests a link to oxida-tive pathogen clearance by neutrophils. Here we use oxidised model substrates and inhibitors to confirm this observation and to show that neutrophil elastase is specifically selective for the di-oxygenated methionine sulfone rather than the mono-oxygenated methionine sulfoxide. We also posit a critical role for ordered solvent in the mechanism of HNE discrimination between the two oxidised forms methionine residue. Preference for the sulfone form of oxidised methionine is especially significant. While both host and pathogens have the ability to reduce methionine sulfoxide back to methionine, a biological pathway to reduce methionine sulfone is not known. Taken to-gether, these data suggest that the oxidative activity of neutrophils may create rapidly cleaved elas-tase “super substrates” that directly damage tissue, while initiating a cycle of neutrophil oxidation that increases elastase tissue damage and further neutrophil recruitment

    Serial killing and the postmodern self

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    © 2006 by SAGE PublicationsThe self has been a consistently central theme in philosophy and the social sciences and, in the last decades of the 20th century, the fragmentation of the modern self has engendered extensive academic commentary. In order to contribute to current discussions about self, it is perhaps most effective to map the transformation of a single representation of the self in contemporary culture. As a cultural ‘flashpoint’, the serial killer could provide an apposite analytical focus. Drawing critically on Mark Seltzer's work on serial killers this article interprets serial killing as a form of commodified transgression. In contrast to the modern self, established through state-institutionalized routines, serial killers establish their identities through ecstatic intercourse. These acts of bodily and ethical transgression are facilitated by the use of commodities. In this way, the serial killer represents a self which is consistent with the colonization of interpersonal relations by multinational capital. The serial killer signifies the appearance of a postmodern self
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