College Student Perceptions of the Romantic Relationships for People with Disabilities

Involvement in romantic relationships is an important biological and social need for many human beings. This desire is just as strong in people who have developmental and intellectual disabilities. However, there is a strong social stigma attached to the sexuality of people who have disabilities. Unfortunately, if these negative perceptions continue to permeate among the general population, people with disabilities may begin to internalize the negative attitudes. Building on previous findings, the current study will examine if college students have negative perceptions of the romantic relationships of people with disabilities, and, if so, what demographics variables moderate these perceptions. Data will be collected from undergraduate general psychology students using an online survey. Data will be collected and analyzed prior to presentation. I hypothesize that participants will generally have negative views on the romantic relationships and sexuality of people with disabilities. Also, I predict that older participants who have a higher class standing and/or no religious affiliation will have more positive attitudes towards the romantic relationships and sexuality of people with disabilities than other students. With a better understanding of the perceptions that exist and what demographic variables interact with these perceptions, work can be done to eliminate negative attitudes

An exploration of the relationship between autism spectrum disorders, theory of mind and the serotonin transporter promoter length polymorphism

Includes bibliographical referencesAutism Spectrum Disorder (ASD) is a highly heritable prevalent pervasive developmental disorder. All cases have deficits in social communication and interaction and in restricted and repetitive behaviours and interests. The mechanisms underlying different clinical presentations remain elusive. Deficits in Theory of Mind (ToM), the ability to understand that others have mental states independent of one's own, have been suggested as a possibly underlying the socia l deficits in ASD. The serotonin transporter promoter length polymorphism (5 - HTTLPR) has been implicated in ASD, and as serotonin is implicated in social functioning more generally, it is possible that 5 - HTTLPR could underlie social functioning in ASD. As such, ToM and 5 - HTTLPR have been implicated in ASD, and specifically as underlying the social deficits typical of this disorder. This protocol assessed core ASD symptoms (i.e. deficits in social communication and interaction, and impairment in restricted and repetitive behaviours and interests) in 69 children with ASD between the ages of 7 and 14 years. The Autism Social Skills Profile, Social Communication Questionnaire, and Repetitive Behavior Scale - Revised assessed these symptoms. 5 - HTTLPR genotypes were established for 55 of these children. ToM was comprehensively assessed in 57 of the children using the University of Cape Town Autism Research Group's Theory of Mind Battery. This protocol is the first is a series of studies assessing the biological bases for social deficits in ASD. One of the main aims was to pilot the use of ASD scales in a local sample. The preliminary analyses assessed the performance of these scales. This data was also used to assess whether the new DSM - 5's merging of social communication and social interaction into a single domain was supported. Study One then assessed for possible relationships between 5 - HTTLPR and cores ASD symptoms, and hypothesised that the 5 - HTTLPR genotype with the most reduced serotonergic transmission woul d relate to increased deficits in social communication and interaction. Study Two explored possible relationships between core ASD symptoms and ToM, and between 5 - HTTLPR and ToM. It was expected that impairment in social communication and interaction would correlation with reduced ToM ability, and that ToM would be most impaired in children with the genotype with the most reduced serotonergic transmission. Preliminary analyses found the scales did not perform well in a local sample. This was likely due to cultural, socio - economic, and educational factors. The bluntness of the scales 13 and broad nature of ASD characteristics likely also contributed. The DSM - 5's diagnostic criteria were supported. Study One and Study Two found no relationships between core ASD symptoms, ToM, and 5 - HTTLPR. Core ASD symptoms were assessed very broadly and it was not possible to establish clear phenotypes for the participants, which likely undermined analyses. At most this protocol showed that broad assessment of core ASD symptoms is not specific enough to reveal relationships to underlying mechanisms, and that ToM and 5 - HTTLPR are not implicated when board measures are used. We emphasise the need for better measures in ASD. We also believe the serotonin system needs to be investigated beyond 5 - HTTLPR in AS

Reproducing the South: William Faulkner, pregnancy and the contemporary US novel

This thesis identifies pregnancy as an overlooked but significant motif in Faulkner's work which develops his major themes of southern blood politics and white supremacy, as well as the role of aesthetic production and the writer in a rapidly modernizing world. It argues that, although the major studies of Faulkner's female characters do not discuss the significance of pregnancy in this work, contemporary US writers have found the theme a significant source of inspiration. It examines how these novelists are re-writing Faulkner's pregnant characters to engage with debates about southern literary genealogies, Faulkner’s role in shaping cultural representations of the contemporary South, as well as his place in the American canon more generally. The first chapter draws out the importance of pregnancy to some of the most significant themes Faulkner re-examines so obsessively across his major novels of the 1930s. The subsequent three chapters reveal how seemingly disparate contemporary novelists – including Larry Brown, Jesmyn Ward, Suzan-Lori Parks and Jayne Anne Philips – are producing novels which focus on characters who are recognizable re-inscriptions of Faulkner’s pregnant protagonists, in sustained interrogations of Faulkner's place in the literary heritage that shapes their writing. In doing so, this thesis contributes to the ongoing critical debate concerned with the nature and extent of Faulkner's continued influence over contemporary literature, and demonstrates that his work continues to be a generative topic for today's novelists, even as the world they write about becomes increasingly removed from Yoknapatawpha

Treating infections caused by carbapenemase-producing Enterobacterales (CPE): a pragmatic approach to antimicrobial stewardship on behalf of the UKCPA Pharmacy Infection Network (PIN)

open access articleThe emergence of carbapenemase-producing Enterobacterales (CPE) as a major cause of invasive infection both within the UK and internationally poses a very real concern for all providers of healthcare. The burden of morbidity and mortality associated with CPE infections is well described. The need for early, targeted, effective and safe antimicrobial therapy remains key for the management of these infected patients yet reliable antimicrobial treatment options remain scarce. In the absence of a universal treatment for these CPE invasive infections, individual treatment options tailored to susceptibilities and severity of infection are required. This working group from within the UK Clinical Pharmacy Association (UKCPA) Pharmacy Infection Network has developed evidence-based treatment recommendations to support infection specialists in managing these complex infections. A systematic review of peer-reviewed research was performed and analysed. We report consensus recommendations for the management of CPE-associated infections. The national expert panel makes therapeutic recommendations regarding the pharmacokinetic and pharmacodynamic properties of the drugs and pharmacokinetic targets, dosing, dosage adjustment and monitoring of parameters for novel and established antimicrobial therapies with CPE activity. This manuscript provides the infection specialist with pragmatic and evidence-based options for the management of CPE infections

Intensive Archaeological Survey of the Carmel Development Municipal Utility District 2 Project, Travis County, Texas

At the request of Carmel Devco, Inc., Pape-Dawson conducted an intensive archaeological survey of the eastern portion of the proposed Carmel Development Project in northeastern Travis County, Texas. The project involves the construction of a new municipal utility district (MUD 2) within the 341-acre (138.1- hectare [ha]) project area. No impacts are planned adjacent to or within the floodplain of Wilbarger Creek and its tributaries, which composes approximately 70 acres (28.3 ha) of MUD 2. Thus, archaeological investigations were conducted within the remaining 271.4 acres (109.8 ha). The depths of impacts vary, but typically road construction impacts are 4 to 5 feet (ft) (1.22 to 1.52 meters [m]) deep, while underground utility installations may impact up to 12 ft (3.66 m) deep. A MUD is a political subdivision of the State of Texas authorized by the Texas Commission of Environmental Quality to provide water, sewage, drainage, and other services within the MUD boundaries. Based on MUD 2’s status as a political subdivision of the state, compliance with the Antiquities Code of Texas is necessary. As no federal funding or permitting is anticipated for this project, compliance with Section 106 of the National Historic Preservation Act (NHPA) will not be necessary. The investigation was conducted in compliance with the Antiquities Code of Texas under Antiquities Permit No. 7519. The purpose of the investigations was to identify all historic or prehistoric cultural resources located within the project area and to evaluate the significance and eligibility of identified resources for designation as a State Antiquities Landmark (SAL). All work was done in accordance with the archaeological survey standards and guidelines as developed by the Council of Texas Archaeologists (CTA) and adopted by the Texas Historical Commission (THC). The investigations included a cultural resources background literature and records review and an intensive pedestrian survey with shovel testing. The background review revealed that portions of the project area have been previously surveyed, and two previously recorded sites (41TV2521 and 41TV2522) are within the project area. In addition, the Pfluger Cemetery (commemorated by an Official Texas Historical Marker) is adjacent to the project area, along with site 41TV2453. Pape Dawson’s intensive archaeological survey included pedestrian survey and the excavation of 68 shovel tests on January 28 and 29, February 2 and 3, and June 7, 8, 15, and 16, 2016. The survey encountered extensive agricultural fields affording greater than 30 percent ground surface visibility; therefore, did not meet the CTA/THC standards, which require 1 shovel test per 3 acres for a project of this size. A total of ten shovel tests was positive for cultural material. Two previously recorded sites (41TV2521 and 41TV2522) were revisited and combined along with a third locus into one larger site, 41TV2521. In addition, archaeological site 41TV2527 and one isolated find were newly documented. Investigations found no evidence that adjacent site 41TV2453 extended into the project area. Sites 41TV2521 and 41TV2527 are likely part of the same historic landscape and date from the late-nineteenth to mid-twentieth centuries. Archival research indicates these sites are associated with the Bohls and Dossmann families and their tenants or laborers. Sites 41TV2521 and 41TV2527 were evaluated according to the criteria in 13 Texas Administrative Code (TAC) 26.10. Both sites were recorded based upon encountering shallowly buried cultural material in shovel tests or on the surface in a disturbed context and each site lacks intact features. Neither site possesses unique or rare attributes concerning Texas history or has the potential to contribute to a better understanding of Texas history by the addition of new and important information. Archival research did not identify any specific individuals associated with sites 41TV2521 and 41TV2527 that are significant on the local or national level. Based on these criteria, neither site is recommended eligible for designation as an SAL, and Pape-Dawson recommends no further archaeological work at sites 41TV2521 and 41TV2527. Diagnostic artifacts, project records, and photographs will be curated at the Center for Archaeological Studies at Texas State University

Reshaping consent so we might improve participant choice (II) : helping people decide

All articles in Research Ethics are published as open access. There are no submission charges and no Article Processing Charges as these are fully funded by institutions through Knowledge Unlatched, resulting in no direct charge to authors. For more information about Knowledge Unlatched please see here: http://www.knowledgeunlatched.orgPeer reviewe

Responding to symptoms suggestive of lung cancer: a qualitative interview study.

BACKGROUND: Late diagnosis of lung cancer can impact on survival rates. Patients delay seeking help for a number of reasons. This study explored symptom appraisal and help-seeking decisions among patients referred to specialist respiratory services with symptoms suggestive of lung cancer. METHODS: In-depth qualitative interviews with patients as soon as possible after referral, ideally before diagnosis and mainly within 10 weeks, explored factors impacting on their pathways prior to referral. Framework analysis, underpinned by the Model of Pathways to Treatment, was used to explore the data with particular focus on patients' beliefs and experiences, disease factors and healthcare professional influences. RESULTS: 35 patients were interviewed (aged 41-88 years, 15 women, 17 with lung cancer). All described similar presenting symptoms and triggers to seek help. Appraisal of symptoms was influenced by whether they had a lung comorbidity; seriousness of symptoms was interpreted within the context of previous illness experiences. Help-seeking was triggered when: symptoms failed to respond as expected; there was an increased awareness of symptoms of lung cancer; the public nature of a cough meant others were able to endorse help-seeking. Almost half visited the general practitioner (GP) two or more times before referral; during this period they reinterpreted initial symptoms and appraised new symptoms. The meaning given to symptoms changed over time and many became increasingly concerned they may have lung cancer. The GP played a role in ensuring timely further help-seeking but often there was little guidance on how to monitor symptoms or when to reconsult. CONCLUSIONS: Patients diagnosed with and without lung cancer had similar symptom pathways. Findings provide guidance for lung cancer awareness campaigns on the importance of social networks in endorsing patient help-seeking. The importance of appropriate advice, monitoring and safety-netting procedures by GPs for people presenting with symptoms suggestive of lung cancer is also highlighted.This report presents independent research funded by the National Institute for Health Research Programme Grants for Applied Research programme (RP-PG-0608-10045).This is the final version. It was first published by BMJ Group at http://bmjopenrespres.bmj.com/content/1/1/e00006

Surfactant-Associated Bacteria in the Near-Surface Layer of the Ocean

Certain marine bacteria found in the near-surface layer of the ocean are expected to play important roles in the production and decay of surface active materials; however, the details of these processes are still unclear. Here we provide evidence supporting connection between the presence of surfactant-associated bacteria in the near-surface layer of the ocean, slicks on the sea surface, and a distinctive feature in the synthetic aperture radar (SAR) imagery of the sea surface. From DNA analyses of the in situ samples using pyrosequencing technology, we found the highest abundance of surfactant-associated bacterial taxa in the near-surface layer below the slick. Our study suggests that production of surfactants by marine bacteria takes place in the organic-rich areas of the water column. Produced surfactants can then be transported to the sea surface and form slicks when certain physical conditions are met. This finding has potential applications in monitoring organic materials in the water column using remote sensing techniques. Identifying a connection between marine bacteria and production of natural surfactants may provide a better understanding of the global picture of biophysical processes at the boundary between the ocean and atmosphere, air-sea exchange of greenhouse gases, and production of climate-active marine aerosols

Health, ethics and environment: A qualitative study of vegetarian motivations

This qualitative study explored the motivations of vegetarians by means of online ethnographic research with participants in an international message board. The researcher participated in discussions on the board, gathered responses to questions from 33 participants, and conducted follow-up e-mail interviews with eighteen of these participants. Respondents were predominantly from the US, Canada and the UK. Seventy per cent were female, and ages ranged from 14 to 53, with a median of 26 years. Data were analysed using a thematic approach. While this research found that health and the ethical treatment of animals were the main motivators for participants’ vegetarianism, participants reported a range of commitments to environmental concerns, although in only one case was environmentalism a primary motivator for becoming a vegetarian. The data indicates that vegetarians may follow a trajectory, in which initial motivations are augmented over time by other reasons for sustaining or further restricting their diet