Interprofessional learning in practice: The student experience

Interprofessional learning and the development of teamworking skills are recognised as essential for patient care and are also a government priority for undergraduate education. Sixteen occupational therapy students worked on an interprofessional training ward as part of their practice placement and three of them participated in an evaluation using the nominal group technique. Despite this small number, the evaluation identifies the value of this learning experience in giving the students an opportunity to appreciate the importance of interpersonal skills; to learn about other team members’ roles; and to experience the challenges of working on a busy rehabilitation ward for older people

Evaluation of high temperature structural adhesives for extended service, phase 4

The evaluation of three phenylquinoxaline polymers as high temperature structural adhesives is presented. These included an experimental crisskubjabke oiktner (X-PQ) and two experimental materials (PPQ-2501) and (PPQ-HC). Lap shear, crack extension, and climing drum peel specimens were fabricated from all three polymers, and tested after thermal, combined thermal/humidity, and stressed Skydrol exposure. All three polymers generally performed well as adhesives at initial test temperatures from 219K (-67 F) to 505K (450 F) and after humidity exposure. The 644K (700 F) cured test specimens exhibited superior Skydrol resistance and thermal stability at 505K (450 F) when compared to the 602K (625 F) cured test specimens

Measurements at low energies of the polarization-transfer coefficient Kyy' for the reaction 3H(p,n)3He at 0 degrees

Measurements of the transverse polarization coefficient Kyy' for the reaction 3H(p,n)3He are reported for outgoing neutron energies of 1.94, 5.21, and 5.81 MeV. This reaction is important both as a source of polarized neutrons for nuclear physics experiments, and as a test of theoretical descriptions of the nuclear four-body system. Comparison is made to previous measurements, confirming the 3H(p,n)3He reaction can be used as a polarized neutron source with the polarization known to an accuracy of approximately 5%. Comparison to R-matrix theory suggests that the sign of the 3F3 phase-shift parameter is incorrect. Changing the sign of this parameter dramatically improves the agreement between theory and experiment.Comment: 12 pages, RevTeX, 5 eps figures, submitted to Phys. Rev.

Influence of shock wave propagation on dielectric barrier discharge plasma actuator performance

Interest in plasma actuators as active flow control devices is growing rapidly due to their lack of mechanical parts, light weight and high response frequency. Although the flow induced by these actuators has received much attention, the effect that the external flow has on the performance of the actuator itself must also be considered, especially the influence of unsteady high-speed flows which are fast becoming a norm in the operating flight envelopes. The primary objective of this study is to examine the characteristics of a dielectric barrier discharge (DBD) plasma actuator when exposed to an unsteady flow generated by a shock tube. This type of flow, which is often used in different studies, contains a range of flow regimes from sudden pressure and density changes to relatively uniform high-speed flow regions. A small circular shock tube is employed along with the schlieren photography technique to visualize the flow. The voltage and current traces of the plasma actuator are monitored throughout, and using the well-established shock tube theory the change in the actuator characteristics are related to the physical processes which occur inside the shock tube. The results show that not only is the shear layer outside of the shock tube affected by the plasma but the passage of the shock front and high-speed flow behind it also greatly influences the properties of the plasma

Measuring hydraulic fracture apertures: A comparison of methods

Hydraulic fracture apertures predominantly control fluid transport in fractured rock masses. Hence, the objective of the current study is to investigate and compare three different laboratory-scale methods to determine hydraulic apertures in fractured (Fontainebleau and Flechtinger) sandstone samples with negligible matrix permeability. Direct measurements were performed by using a flow-through apparatus and a transient-airflow permeameter. In addition, a microscope camera permitted measuring the mechanical fracture apertures from which the corresponding hydraulic apertures were indirectly derived by applying various empirical correlations. Single fractures in the sample cores were generated artificially either by axial splitting or by a saw cut resulting in hydraulic apertures that ranged between 8 and 66 µm. Hydraulic apertures, accurately determined by the flow-through apparatus, are used to compare results obtained by the other methods. The transient-airflow permeameter delivers accurate values, particularly when repeated measurements along the full fracture width are performed. In this case, the derived mean hydraulic fracture apertures are in excellent quantitative agreement. When hydraulic apertures are calculated indirectly from optically determined mechanical apertures using empirical equations, they show larger variations that are difficult to compare with the flow-through-derived results. Variations in hydraulic apertures as observed between methods are almost certainly related to differences in sampled fracture volume. Overall, using direct flow-through measurements as a reference, this study demonstrates the applicability of portable methods to determine hydraulic fracture apertures at both the laboratory and outcrop scales

A transient homotypic interaction model for the influenza A virus NS1 protein effector domain

Influenza A virus NS1 protein is a multifunctional virulence factor consisting of an RNA binding domain (RBD), a short linker, an effector domain (ED), and a C-terminal 'tail'. Although poorly understood, NS1 multimerization may autoregulate its actions. While RBD dimerization seems functionally conserved, two possible apo ED dimers have been proposed (helix-helix and strand-strand). Here, we analyze all available RBD, ED, and full-length NS1 structures, including four novel crystal structures obtained using EDs from divergent human and avian viruses, as well as two forms of a monomeric ED mutant. The data reveal the helix-helix interface as the only strictly conserved ED homodimeric contact. Furthermore, a mutant NS1 unable to form the helix-helix dimer is compromised in its ability to bind dsRNA efficiently, implying that ED multimerization influences RBD activity. Our bioinformatical work also suggests that the helix-helix interface is variable and transient, thereby allowing two ED monomers to twist relative to one another and possibly separate. In this regard, we found a mAb that recognizes NS1 via a residue completely buried within the ED helix-helix interface, and which may help highlight potential different conformational populations of NS1 (putatively termed 'helix-closed' and 'helix-open') in virus-infected cells. 'Helix-closed' conformations appear to enhance dsRNA binding, and 'helix-open' conformations allow otherwise inaccessible interactions with host factors. Our data support a new model of NS1 regulation in which the RBD remains dimeric throughout infection, while the ED switches between several quaternary states in order to expand its functional space. Such a concept may be applicable to other small multifunctional proteins

Advancing the time of ripeness of grapes by the application of methyl 2-(ureidooxy) propionate (a growth retardant)

Methyl 2-(ureidooxy) propionate (MUP), a plant growth retardant, hastened the ripening of grape berries of Vitis vinifera L. cultivars Mataro and Sultana by about 2 weeks and 1 week, respectively. The vines were sprayed with 0.1 % solution of MUP about halfway :through the first rapid growth phase of the fruit and again 2 weeks later. Terminal and lateral shoot growth was inhibited. Ripening of berries was advanced as measured by development of colour, and changes in titratable acid and reducing sugar content. The earlier ripening of the berries may have been due to hormonal changes but the advancement was much greater than that found previously with abscisic acid or ethylene applied during the slow growth stage of berry development.Die Beschleunigung des Reifezeitpunktes von Trauben durch die Anwendung vonMethyl-2-(ureidooxy)-Propionat, einen WachstumsdämpferMethyl-2-(ureidooxy)-Propionat (MUP), welches das Pflanzenwachstum verlangsamt, beschleunigte bei den Vitis-vinifera-Sorten Mataro und Sultana die Beerenreife um etwa 2 Wochen bzw. 1 Woche. Die Reben wurden etwa in der Mitte der ersten raschen Wachstumsphase der Beeren und ein weiteres Mal 2 Wochen später mit einer 0,1%igen MUP-Lösung besprüht. Das terminale und laterale Triebwachstum war gehemmt. Die Beerenreife war beschleunigt, wie die Entwicklung der Beerenfarbe und die Veränderungen im Gehalt an titrierbarer Säure und reduzierenden Zuckern zeigten. Die frühzeitigere Beerenreife könnte auf hormonale Veränderungen zurückgehen; allerdings war die Reife viel stärker beschleunigt als im Fall früherer Versuche, in denen während der langen Wachstumsphase der Beerenentwicklung Abscisinsäure oder Äthylen angewandt worden waren