Manifesto for the future of work and organizational psychology

This manifesto presents 10 recommendations for a sustainable future for the field of Work and Organizational Psychology. The manifesto is the result of an emerging movement around the Future of WOP (seewww.futureofwop.com), which aims to bring together WOP-scholars committed to actively contribute to building a better future for our field. Our recommendations are intended to support both individuals and collectives to become actively engaged in co-creating the future of WOP together with us. Therefore, this manifesto is openand never“finished.”It should continuously evolve, based on an ongoing debate around our professional values and behavior. This manifesto is meant, first of all, for ourselves as an academic community. Furthermore, it is also important for managers, decision makers, and other stakeholders and interested parties,such as students, governments and organizations, as we envision what the future of WOP could look like, and it is only through our collective efforts that we will be able to realize a sustainable future for all of us

An Introduction to Enquiry/ Problem-based Learning, Maynooth: Facilitate and the All Ireland Society for Higher Education (AISHE)

The booklet is organized into two sections. Part 1 provides an overview which answers the broad question of what is enquiry/problembased learning. Part 2 presents four case studies of enquiry/problem-based learning. The booklet draws on a few key texts but particularly on another publication by Barrett and Cashman (eds) entitled A Practitioner’s Guide to Enquiry and Problem-based Learning (201

An Introduction to Enquiry/ Problem-based Learning, Maynooth: Facilitate and the All Ireland Society for Higher Education (AISHE)

The booklet is organized into two sections. Part 1 provides an overview which answers the broad question of what is enquiry/problembased learning. Part 2 presents four case studies of enquiry/problem-based learning. The booklet draws on a few key texts but particularly on another publication by Barrett and Cashman (eds) entitled A Practitioner’s Guide to Enquiry and Problem-based Learning (201

An Introduction to Enquiry/ Problem-based Learning, Maynooth: Facilitate and the All Ireland Society for Higher Education (AISHE)

The booklet is organized into two sections. Part 1 provides an overview which answers the broad question of what is enquiry/problembased learning. Part 2 presents four case studies of enquiry/problem-based learning. The booklet draws on a few key texts but particularly on another publication by Barrett and Cashman (eds) entitled A Practitioner’s Guide to Enquiry and Problem-based Learning (201

Effect of reactive site loop elongation on the inhibitory activity of C1-inhibitor

The serine protease inhibitor C1-Inhibitor (C1-Inh) inhibits several complement- and contact-system proteases, which play an important role in inflammation. C1-Inh has a short reactive site loop (RSL) compared to other serpins. RSL length determines the inhibitory activity of serpins. We investigated the effect of RSL elongation on inhibitory activity of C1-Inh by insertion of one or two alanine residues in the RSL. One of five mutants had an increased association rate with kallikrein, but was nevertheless a poor inhibitor because of a simultaneous high stoichiometry of inhibition (>10). The association rate of the other variants was lower than that of wild-type C1-Inh. These data suggest that the relatively weak inhibitory activity of C1-Inh is not the result of its short RSL. The short RSL of C1-Inh has, surprisingly, the optimal length for inhibition. (C) 2004 Elsevier B.V. All rights reserved

How Does Scientific Argumentation Differ from the Opinion of Scientists? A Response to Siegel (2022)

Recently, the Journal of Management Studies (JMS) has published an interesting debate on the Responsible Research in Business and Management Initiative (RRBM) and the role of our research for the benefit of society, organizations, and workers (Siegel, 2022; Tsui & McKiernan, 2022). While this discussion published in the JMS Point-Counterpoint section is very relevant, in this blog we want to raise some issues in response to Siegel’s (2022) contribution. The discussion published in JMS was meant to provoke debate, and explicitly aimed at capturing ‘extreme opinions’. The question, however, is where are the boundaries of such ‘extreme opinions’? What does actually constitute valid academic argumentation? In this blog, we problematize some of Siegel’s statements. Siegel has an extended publication record in top-tier journals, as well as editorial positions, including a former editor-in-chief for JMS. He, therefore, carries an additional responsibility due to his elite status. Likewise, his former editorship of JMS may have given him a special status, which allows him greater freedom in writing compared to those who may not have such privileges. At the same time, critique on his work is more difficult to publish, based on his elite status

C-Reactive Protein Activates Complement in Infarcted Human Myocardium

Circulating levels of C-reactive protein (CRP) constitute a cardiovascular risk marker. Immunohistochemical studies have revealed co-localization of CRP and activated complement in human infarcted myocardium suggesting CRP to enhance inflammation in ischemic myocardium by inducing local complement activation. The aim was to establish whether CRP activates complement in infarcted human myocardium and to assess the relationship between this activation and the duration of infarction. Myocardial tissue samples from 56 patients that had died from acute myocardial infarction were evaluated. Specimens were taken from infarcted as well as noninfarcted sites of the heart. CRP-mediated complement activation was assessed by immunohistochemistry and by measuring levels of complement, CRP, and CRP-complement complexes, specific markers for CRP-mediated activation, in homogenates of the heart. Infarctions of 12 hours to 5 days had significantly more extensive depositions of complement and CRP and contained significantly more CRP, activated complement, and CRP-complement complexes than infarctions that were less than 12 hours old. Levels of CRP complexes correlated significantly with CRP and complement concentrations in the infarctions, as well as with the extent of complement and CRP depositions as measured via immunohistochemistry. Specific activation products of CRP-mediated activation of complement are increased in infarcts of more than 12 hours in duration and correlate with the extent of complement depositions. Hence, CRP seems to enhance local inflammatory reactions ensuing in human myocardial infarcts of more than 12 hours duration