525 research outputs found
Future scope and directions of nanotechnology in creating next-generation supercapacitors
The primary global research scheme of the 21st century is nanotechnology. Looking forward to the future, nanotechnologies’ generalized diffusion will seem to turn them into supplies, generating more space for privileged and superior values of applications such as information technology, nanoenergy, nanobiotechnologies, and nanomaterials.1-5 In general, nanotechnology is the understanding and controlling of the matters of dimensions of approximately 1-100 nm, in which a unique phenomenon facilitates novel applications.2 The application domains covered by nanotechnology are discussed in detail in this chapter
Experimental studies of the processes occuring in ion plating discharges
A theoretical study of the processes occurring in ion plating is carried out and the potential of various mechanisms affecting properties of ion-plated films is studied. Three pieces of apparatus are designed and developed to study the contributions of the mechanisms responsible for the properties of ionplated films.A thorough experimental investigation of the processes occurring in ion plating discharges is carried out
Low secondary electron yield engineered surface for electron cloud mitigation
Secondary electron yield (SEY or δ) limits the performance of a number of devices. Particularly, in high-energy charged particle accelerators, the beam-induced electron multipacting is one of the main sources of electron cloud (e-cloud) build up on the beam path; in radio frequency wave guides, the electron multipacting limits their lifetime and causes power loss; and in detectors, the secondary electrons define the signal background and reduce the sensitivity. The best solution would be a material with a low SEY coating and for many applications δ < 1 would be sufficient. We report on an alternative surface preparation to the ones that are currently advocated. Three commonly used materials in accelerator vacuum chambers (stainless steel, copper, and aluminium) were laser processed to create a highly regular surface topography. It is shown that this treatment reduces the SEY of the copper, aluminium, and stainless steel from δmax of 1.90, 2.55, and 2.25 to 1.12, 1.45, and 1.12, respectively. The δmax further reduced to 0.76-0.78 for all three treated metals after bombardment with 500 eV electrons to a dose between 3.5 × 10-3 and 2.0 × 10-2 C·mm-2
Epidemiological alteration in pathogens found in ground meat in Iran: unexpected predominance of vancomycin-resistant Enterococcus faecalis
Colonization of the human and animal intestinal tract with potential pathogenic bacteria is correlated with the risk of contamination of food products. The current study analyzed the prevalence of Enterococcus faecalis and Escherichia coli O157H7 in ground meat in Ilam, Iran. Both index organisms were identified following standard food microbiological methods. For E. faecalis, the susceptibility to vancomycin was tested, and PCR was used to check for the vanA gene. E. faecalis was present in all 24 ground meat samples, with no E. coli O157H7 detected in samples. The analysis showed the presence of the vanA gene in 5/24 vancomycin resistant enterococci. In conclusion, this study for the first time demonstrates the presence of vancomycin-resistant enterococci in ground meat in Iran. This observation warrants further epidemiologic investigation and should be followed up in the future
The "Mohazell" herbal formula in combination with a calorie-restricted diet can improve systemic inflammation in obesity: A randomized double-blind, clinical trial
Inflammation is one of the primary mechanisms involved in the development of metabolic complications. The aim of the present study was to determine the effects of "Mohazell", a traditional herbal formula consisting of Origanum vulgare, Carumcarvi, Trachyspermum copticum and Ruta Graveolen in combination with a calorie-restricted diet on biomarkers of systemic inflammation in obese adults. In this double-blind placebo-controlled randomized clinical trial, 68 volunteer obese (Body mass index: 30-35 kg/m2) subjects aged 25-50 years were recruited. Participants were randomly divided into two groups, an intervention group (n=34) and a placebo group (n=34). Each group received either: (1) a low-calorie diet with 3 g/day of 'Mohazell' or (2) a low-calorie diet with 3 g/day placebo for 8 weeks. Patients weight was measured, their BMI was calculated and biochemical parameters such as high Sensitivity C-reactive protein (hs-CRP), tumor necrosis factor-alpha (TNF-α) and IL-6 were measured at baseline and after the intervention. No side effects were reported with the 'Mohazell' supplementation. 'Mohazell' decreased serum levels of TNF-α (p=0.001) and hs-CRP (p=0.04) in the treatment group. Also, IL-6 decreased insignificantly in both groups (p=0.78). Additionally, significant reductions were observed for weight, BMI, Energy and macronutrients (p<0.05). There were statistically significant differences for weight (0.023), BMI (0.046) and TNF-α (0.001) in between group analysis. The 'Mohazell' supplementation combined with a calorie-restricted diet may modulate systemic inflammatory biomarkers in obese adults. However, more studies are needed to clarify the efficacy of 'Mohazell' as an adjunct therapy to improve inflammatory parameters in obese subjects. © Mattioli 1885
Comparison of quadruple and triple Furazolidone containing regimens on eradication of helicobacter pylori
Background: The effectiveness of classic standard triple therapy regimen of helicobacter pylori (H. pylori) eradication has decreased to unacceptably low levels, largely related to development of resistance to metronidazole and clarithromycin. Thus successful eradication of H. pylori infections remains challenging. Therefore alternative treatments with superior effectiveness and safety should be designed and appropriately tested in all areas depending on the native resistance patterns. Furazolidone has been used successfully in eradication regimens previously and regimens containing furazolidone may be an ideal regimen. Methods: H. pylori infected patients with proven gastric or duodenal ulcers and /or gastric or duodenal erosions at Imam Khomeini Hospital in Sari/Northern Iran, were randomly allocated into three groups: group A (OABF) with furazolidone (F) (200 mg bid.), group B (OABM-F) metronidazole (M) (500 mg bid.) for the first five days, followed by furazolidone (F) (200 mg bid.) for the second five days and group C (OAF) with furazolidone (F) (200 mg tid.). Omeprazole (O) (20 mg bid.) and amoxicillin (A) (1000 mg bid.) were given in all groups; bismuth (B) (240 mg bid.) was prescribed in groups A&B. Duration of all eradication regimens were ten days. Eight weeks after treatment, a 14C-urea breath test was performed for evaluation of H. pylori eradication. Results: A total of 372 patients were enrolled in three groups randomly (124 patients in each group); 120 (97) patients in group A (OABF), 120 (97) in group B (OABM-F) and 116 (93) in group C (OAF) completed the study. The intention-to-treat eradication rates were 83.7 (95 CI= 77.3-90.4), 79.8 (95 CI= 72.6-87), and 84.6 (95 CI= 78.2-91.1) and per-protocol eradication rates were 86.6 (95 CI= 80.5-92.8), 82.5 (95 CI= 75.6-89.4), and 90.5 (95 CI= 85.1-95.9) for groups OABF, OABM-F, and OAF, respectively. No statistical significant differences were found in case of severe drug adverse effects between the above mentioned three groups (p> 0.05). The most common side effects, namely nausea and fever, occurred in all groups, but more frequently in group C (OAF) (p< 0.05). Conclusion: In developing countries such as Iran, furazolidone-based regimens can substitute clarithromycinbased regimens for H. pylori eradication because of a very low level of resistance, low cost and high effectiveness. Considering per-protocol eradication rate of ten days OAF regimen, and the acceptable limit of ninety percent, we recommend this regimen in developing countries such as Iran to be substituted of classic standard triple therapy. In order to minimize rare serious adverse effects, one week high dose OAF regimen should be taken into consideration in other studies
A Multi-Armed Bandit to Smartly Select a Training Set from Big Medical Data
With the availability of big medical image data, the selection of an adequate
training set is becoming more important to address the heterogeneity of
different datasets. Simply including all the data does not only incur high
processing costs but can even harm the prediction. We formulate the smart and
efficient selection of a training dataset from big medical image data as a
multi-armed bandit problem, solved by Thompson sampling. Our method assumes
that image features are not available at the time of the selection of the
samples, and therefore relies only on meta information associated with the
images. Our strategy simultaneously exploits data sources with high chances of
yielding useful samples and explores new data regions. For our evaluation, we
focus on the application of estimating the age from a brain MRI. Our results on
7,250 subjects from 10 datasets show that our approach leads to higher accuracy
while only requiring a fraction of the training data.Comment: MICCAI 2017 Proceeding
One Anastomosis/Mini-Gastric Bypass (OAGB/MGB) as Revisional Surgery Following Primary Restrictive Bariatric Procedures: a Systematic Review and Meta-Analysis
One anastomosis gastric bypass (OAGB/MGB) has gained popularity in the past decade. International databases were searched for articles published by September 10, 2020, on OAGB/MGB as a revisional procedure after restrictive procedures. Twenty-six studies examining a total of 1771 patients were included. The mean initial BMI was 45.70 kg/m2, which decreased to 31.52, 31.40, and 30.54 kg/m2 at 1, 3, and 5-year follow-ups, respectively. Remission of type-2 diabetes mellitus (T2DM) following OAGB/MGB at 1-, 3-, and 5-year follow-up was 65.16 ± 24.43, 65.37 ± 36.07, and 78.10 ± 14.19%, respectively. Remission/improvement rate from gastroesophageal reflux disease (GERD). Also, 7.4% of the patients developed de novo GERD following OAGB/MGB. Leakage was the most common major complication. OAGB/MGB appears to be feasible and effective as a revisional procedure after failed restrictive bariatric procedures
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