668 research outputs found
Guidance and support of women in engineering programs at Universidad Tecnologica de Bolivar
Gender equality is one of the sustainable development goals. In STEM areas, it is a requirement to expand and improve women's careers. To increase the participation of women in STEM it is not enough to attract more young women to these programs. It is necessary to provide orientation during the academic programs and ensure safe and rewarding environments so that women can succeed in their studies. The Faculty of Engineering of Universidad Tecnológica de Bolívar has gender gaps in most of its programs and several strategies are being implemented to overcome this situation. This paper analyzes five factors to guide and support women in engineering programs: academic success, protection of women, scholarships and financial assistance, international mobility, and leadership. We present several activities and strategies developed in the last three years in these five factors. The impacts of these strategies cannot be evaluated yet, but we expect that they can improve the well-being of women in engineering and contribute to the reduction of the gender gaps. © 2023 IEEE
ITIL (Information Technology Infrastructure Library) como medio para mejorar la eficacia de los servicios de TI. Un caso de estudio.
El presente trabajo presenta el caso de una gerencia de sistemas de Información de una organización que decidió utilizar a ITIL (Information Technology Index Library) como medio para mejorar la eficacia de los servicios de TI. El caso de estudio incluye tres fases: el diagnóstico del departamento, el diseño y documentación de los procesos de ITIL, incluyendo la metodología de trabajo, y la implantación de estos. Se presentan resultados preliminares derivados de la medición de los procesos.ITESO, A.C
Seroprevalence and risk factors associated with bovine herpesvirus 1 in dairy herds of Colombia
BACKGROUND AND AIM: Infectious bovine rhinotracheitis (IBR) is an infectious disease widely distributed globally and is considered the main cause of various reproductive and respiratory tract diseases in cattle and buffaloes. This study aimed to estimate seroprevalence and determine risk factors associated with the presentation of IBR in the municipality of Sotaquirá, Boyacá (Colombia). MATERIALS AND METHODS: A descriptive cross-sectional study with simple random sampling was performed, and the sample size was 1,000 cattle. Blood samples were obtained by coccygeal venipuncture and processed through indirect enzyme-linked immunosorbent assay using the Synbiotics(®) kit (Zoetis, New Jersey, USA) with a sensitivity and specificity of 96% and 98%, respectively. Data were processed using the statistical program EpiInfo(®) (Centers for Disease Control and Prevention; Atlanta, Georgia). RESULTS: A high seroprevalence of 57.5% was established. Seroprevalence was the highest in cattle >4 years of age (65.0% apparent seroprevalence [AS]; 67% true seroprevalence [TS]) and in the Holstein breed (65.5% AS; 67.8% TS). The breed and age of the animals were significantly associated with each other. The Holstein breed, age group >4 years, uncertified semen, and fetal death were established as risk factors for IBR. In comparison, the age groups of <1 and 1–2 years and the Normande breed were established as protective factors against the bovine herpesvirus-1 virus. CONCLUSION: Management factors, such as livestock from other owners and animal purchases, which affect disease presentation, are evident. The implementation and development of novel prevention and control measures for IBR at the national level are necessary
Estructura factorial de la escala DREEM en estudiantes de medicina chilenos
Indexación: ScieloBackground: The entry to a University requires an adaptation process that not all students solve with the same kind of success. Even though students’ social adaptation and emotional skills are essential, the educational environmental that they perceive has a significant influence in their academic life. Aim: To describe the changes in the perception about academic environment that medical students experience during the first three years of undergraduate career. Material and Methods: The Dundee Ready Education Environment Measure (DREEM) scale was applied to 525 first to third year medical students and an exploratory factorial analysis was made. Results: Four factors were identified: Academic Perception: academic quality that students attribute to the process in which they take part, as well as to the assessment that they do of their learning outcomes (coefficient α = 0.85); Academic Experience: refers to positive emotions that students experience during the career such as confidence, pleasure and energy (coefficient α = 0.76); Atmosphere Perception, comfort and calm that students experiment during their academic activities (coefficient α = 0.79); Teachers Perception: the perception that students have of teachers about their interest and disposition towards students (coefficient α = 0.50). Conclusions: The assessment of academic environment quality is inversely associated with the lapse that the students have spent in their undergraduate careers.
Key words: Education, Medical; Psychometrics; Students, medical; Undergraduate
Seminal plasma AnnexinA2 protein is a relevant biomarker for stallions which require removal of seminal plasma for sperm survival upon refrigeration
Some stallions yield ejaculates that do not tolerate conservation by refrigeration prior to artificial insemination (AI), showing improvement after removal of most of the seminal plasma (SP) by centrifugation. In this study, the SP-proteome of 10 different stallions was defined through high-performance liquid chromatography with tandem mass spectrometry and bioinformatic analysis in relation to the ability of the ejaculates to maintain semen quality when cooled and stored at 5°C. Stallions were classified into three groups, depending on this ability: those maintaining good quality after direct extension in a commercial extender (good), stallions requiring removal of seminal plasma (RSP) to maintain seminal quality (good-RSP), and stallions, unable to maintain good semen quality even after RSP (poor). Pathway enrichment analysis of the proteins identified in whole equine SP using human orthologs was performed using g: profiler showing enriched Reactome and the Kyoto Encyclopedia of Genes and Genomes pathways related to hexose metabolism, vesicle mediated transport, post translational modification of proteins and immune response. Specific proteins overrepresented in stallions tolerating conservation by refrigeration included a peroxiredoxin-6 like protein, and transcobalamin-2, a primary vitamin B12-binding, and transport protein. Also, the protein involved in protein glycosylation, ST3 beta-galactoside alpha-2,3-sialyltransferase 1 was present in good stallions. These proteins were nearly absent in poor stallions. Particularly, annexinA2 appeared as to be the most powerful discriminant variable for identification of stallions needing RSP prior to refrigeration, with a P = 0.002 and a q value = 0.005. Overall this is the first detailed study of the equine SP-proteome, showing the potential value of specific proteins as discriminant bio-markers for clinical classification of stallions for AI
Assessment of psychometric properties of the academic involvement questionnaire, expectations version
Indexación: Web of Science; Scielo.Background: Academic Involvement Questionnaire, Expectations version (CIA-A), assesses the expectations of involvement in studies. It is a relevant predictor of student success. However, the evidence of its validity and reliability in Chile is low, and in the case of Medical students, there is no evidence at all. Aim: To evaluate the factorial structure and internal consistency of the CIA-A in Chilean Medical school freshmen. Material and Methods: The survey was applied to 340 Medicine freshmen, chosen by non-probability quota sampling. They answered a back-translated version of CIA-A from Portuguese to Spanish, plus a sociodemographic questionnaire. For psychometric analysis of the CIA-A, an exploratory factor analysis was carried on, the reliability of the factors was calculated, a descriptive analysis was conducted and their correlation was assessed. Results: Five factors were identified: vocational, institutional and social involvement, use of resources and student participation. Their reliabilities ranged between Cronbach’s alpha values of 0.71 to 0.87. Factors also showed statistically significant correlations between each other. Conclusions: Identified factor structure is theoretically consistent with the structure of original version. It just disagrees in one factor. In addition, the factors’ internal consistency were adequate for using them in research. This supports the construct validity and reliability of the CIA-A to assess involvement expectations in medical school freshmen.http://ref.scielo.org/r2sn6
Plant phenotyping and phenomics for plant breeding
A major challenge for food production in the coming decades is to meet the food demands of a growing population (Beddington, 2010). The difficulty of expanding agricultural land, along with the effect of climate change and the increase in world population are the current societal changes that make necessary to accelerate research to improve yield-potential and adaptation to stressful environments (Lobos et al., 2014; Camargo and Lobos). [...
The Assessment of Myocardial Longitudinal Strain in a Paediatric Spanish Population Using a New Software Analysis
Two-dimensional speckle-tracking echocardiography (2DSTE) has been present for years. However, it is underutilized due to the expertise and time requirements for its analysis. Our aims were to provide strain values in a paediatric Spanish population and to assess the feasibility and reproducibility of a new strain software analysis in our environment. Methods: A cross-sectional study of 156 healthy children aged 6 to 17 years. Longitudinal strain (LS) analysis of the left ventricle, right ventricle, and left atrium was performed. Feasibility and reproducibility were assessed. The associations of clinical and echocardiographic variables with strain values were investigated by multivariate analysis. Results: Mean age was 11 ± 3 years (50% female). Feasibility of LS measurement ranged from 94.2% for left ventricle global LS (LVGLS) to 98.1% for other chamber strain parameters. Strain values were 26.7 ± 2.3% for LVGLS; 30.5 ± 4.4% and 26.9 ± 4% for right ventricle free wall LS (RVFWLS) and four chambers view LS (RV4CLS) respectively; and 57.8 ± 10.5%, 44.9 ± 9.5%, and 12.9 ± 5.5% for left atrium LS reservoir phase (LALSr), conduct phase (LALScd) and contraction phase (LALSct), also respectively. Body surface area (BSA) and age presented a negative correlation with strain values. Higher values were found in females than in males, except for LALScd. Excellent intra- and inter-observer reproducibility were found for right and left ventricular strain measurement, with intraclass correlation coefficients (ICC) ranging from 0.88 to 0.98, respectively. In conclusion, we described strain values in a healthy Spanish paediatric population. LS assessment by this new strain analysis software by semi-automatic manner was highly feasible and reproducible
Estimating Distribution of Hidden Objects with Drones: From Tennis Balls to Manatees
Unmanned aerial vehicles (UAV), or drones, have been used widely in military applications, but more recently civilian applications have emerged (e.g., wildlife population monitoring, traffic monitoring, law enforcement, oil and gas pipeline threat detection). UAV can have several advantages over manned aircraft for wildlife surveys, including reduced ecological footprint, increased safety, and the ability to collect high-resolution geo-referenced imagery that can document the presence of species without the use of a human observer. We illustrate how geo-referenced data collected with UAV technology in combination with recently developed statistical models can improve our ability to estimate the distribution of organisms. To demonstrate the efficacy of this methodology, we conducted an experiment in which tennis balls were used as surrogates of organisms to be surveyed. We used a UAV to collect images of an experimental field with a known number of tennis balls, each of which had a certain probability of being hidden. We then applied spatially explicit occupancy models to estimate the number of balls and created precise distribution maps. We conducted three consecutive surveys over the experimental field and estimated the total number of balls to be 328 (95%CI: 312, 348). The true number was 329 balls, but simple counts based on the UAV pictures would have led to a total maximum count of 284. The distribution of the balls in the field followed a simulated environmental gradient. We also were able to accurately estimate the relationship between the gradient and the distribution of balls. Our experiment demonstrates how this technology can be used to create precise distribution maps in which discrete regions of the study area are assigned a probability of presence of an object. Finally, we discuss the applicability and relevance of this experimental study to the case study of Florida manatee distribution at power plants
Statins: Could an old friend help the fight against COVID-19?
This is the peer reviewed version of the following article: "Statins: Could an old friend help the fight against COVID-19?" . British Journal of Pharmacology (2020): 19 June, which has been published in final form at https://doi.org/10.1111/bph.15166. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versionshe COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has overwhelmed healthcare systems requiring the rapid development of treatments, at least, to reduce COVID-19 severity. Drug repurposing offers a fast track. Here, we discuss the potential beneficial effects of statins in COVID-19 patients based on evidence that they may target virus receptors, replication, degradation, and downstream responses in infected cells, addressing both basic research and epidemiological information. Briefly, statins could modulate virus entry, acting on the SARS-CoV-2 receptors, ACE2 and CD147, and/or lipid rafts engagement. Statins, by inducing autophagy activation, could regulate virus replication or degradation, exerting protective effects. The well-known anti-inflammatory properties of statins, by blocking several molecular mechanisms, including NF-κB and NLRP3 inflammasomes, could limit the "cytokine storm" in severe COVID-19 patients which is linked to fatal outcome. Finally, statin moderation of coagulation response activation may also contribute to improving COVID-19 outcomesThis work and data discussed here were supported by grants from the Instituto de
Salud Carlos III (ISCIII) and Fondos FEDER European Union (PI17/00119 and Red de
Investigación Renal (REDINREN): RD16/0009, to M.R-O, PI17/01495 to J.E, PI18/01133 to
AMR, PI19/00815 to A.O); Comunidad de Madrid (“NOVELREN” B2017/BMD3751
to
M.R-O, B2017/BMD-3686 CIFRA2-CM to A.O); Spanish Ministry of Economy and
Competitiveness MINECO (DTS17/00203, DTS19/00093) to J,E; “Convocatoria
Dinamización Europa Investigación 2019” MINECO (EIN2019-103294 to M.R-O and SR-M);
ERA-PerMed-JTC2018 (KIDNEY ATTACK AC18/00064 and PERSTIGAN AC18/00071)
and DTS18/00032 to A.O; The “Sara Borrell” postdoctoral training program of the ISCIII
supported the salary of SR-M (CD19/00021), IMPROVE-PD project (“Identification and
Management of Patients at Risk–Outcome and Vascular Events in Peritoneal Dialysis”)
funding from the European Union’s Horizon 2020 research and innovation program under the
Marie Skłodowska-Curie Grant Agreement No. 812699 to M.R.O
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