969 research outputs found

    Hyvinvointi varhaiskasvatuksessa työyhteisön ja opettajien näkökulmasta

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    Tiivistelmä. Tässä kandidaatintutkielmassa tarkastellaan varhaiskasvatuksen henkilöstön hyvinvointia ja siihen vaikuttavia tekijöitä niin työyhteisön kuin varhaiskasvatuksen opettajien näkökulmasta. Tutkielmassa kuvataan varhaiskasvatuksen työyhteisön ja opettajien hyvinvoinnin tilaa ja siihen vaikuttavia tekijöitä vastaamalla seuraaviin tutkimuskysymyksiin: Mistä osatekijöistä rakentuu varhaiskasvatuksen työyhteisön hyvinvointi ja Mitkä tekijät vaikuttavat varhaiskasvatuksen opettajien työhyvinvointiin. Kuvailevana kirjallisuuskatsauksena toteutettu tutkielma pohjautuu uudehkoihin tieteellisiin tutkimusartikkeleihin, joiden ohella hyödynnetään vanhempia klassikkoteoksia esimerkiksi teoriataustassa. Tutkielman keskeiset käsitteet ovat hyvinvointi, työhyvinvointi ja varhaiskasvatuksen työyhteisö. Edellä mainitut käsitteet avataan tutkielman teoreettisessa viitekehyksessä. Hyvinvointi nähdään tutkielmassa ilmiönä, johon pystyy vaikuttamaan niin myönteisesti kuin negatiivisesti organisaation ja yksilön toiminnalla. Työhyvinvoinnilla tarkoitetaan tässä tutkielmassa yksilön kokemusta omasta jaksamisestaan suhteessa työhön. Varhaiskasvatuksen työyhteisöllä kuvataan varhaiskasvatusyksikön sosiaalista työympäristöä, jossa työskentelee varhaiskasvatusyksikön johtaja, varhaiskasvatuksen opettajat ja lastenhoitajat sekä varhaiserityisopettaja. Tutkielman tulokset osoittavat, että varhaiskasvatuksessa koettava hyvinvointi rakentuu yhteiskunnan ja varhaiskasvatusyksikön toimintakulttuurin sekä johtamisen luomasta kokonaisuudesta. Keskeisimpänä varhaiskasvatuksen työntekijöiden hyvinvointiin vaikuttavana tekijänä esille nousee yhteiskunnan alhainen arvostus varhaiskasvatustyötä kohtaan, mikä näkyy varhaiskasvatuksessa puutteellisina resursseina. Tämä taas johtaa työntekijöiden kuormittuneisuuteen ja työn mielekkyyden sekä merkityksellisyyden alenemiseen. Yhteiskunnan mahdollistamat resurssit näkyvät toimintakulttuurissa, jonka vuoksi keskeistä on toimiva, ammattitaitoinen johtaminen

    Factor Retention Decisions in Exploratory Factor Analysis Results: A Study Type of Knowledge Management Process at Malaysian University Libraries

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    Structural equation modeling (SEM) is a versatile statistical modeling tool which uses in the social sciences research. Recently, in Library and Information Science (LIS) environment, structural equation modeling has gained popularity across many disciplines, due to its generality and flexibility. Its estimation techniques, modeling capabilities and breadth of application are expanding rapidly.This paper reported a structural equation modeling through an Exploratory Factor Analysis (EFA) result, which involves 300 lead users at six selected Malaysian university libraries through survey. The decision of how many factors to retain is a critical component of exploratory factor analysis. Evidence is presented that parallel analysis is one of the most accurate factor retention methods. SPSS 20 was utilized to analyze the factor analysis data. In this regards, the results of EFA could provide empirical evidence of each hypotheses construct. It is hoped that the EFA results could be used to level Confirmatory Factor Analysis (CFA) to perform full Structural Equation Modeling.© 2013 The Authors. Copyright for this article is retained by the author(s), with first publication rights granted to the journal. This is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).fi=vertaisarvioitu|en=peerReviewed

    Effect of site of lactate infusion on regional lactate exchange in pigs

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    Background The rate of extra-hepatic lactate production and the route of influx of lactate to the liver may influence both hepatic and extra-hepatic lactate exchange. We assessed the dose-response of hepatic and extra-hepatic lactate exchange during portal and central venous lactate infusion. Methods Eighteen pigs randomly received either portal (n=5) or central venous (n=7) lactate infusion or saline (n=6). Sodium lactate was infused at 33, 66, 99, and 133 µmol kg−1 min−1 for 20 min each. Systemic and regional abdominal blood flows and plasma lactate were measured at 20 min intervals until 1 h post-infusion, and regional lactate exchange was calculated (area under lactate uptake-time curve). Results Total hepatic lactate uptake [median (95% confidence interval)] during the experimental protocol (140 min) was higher during portal [8198 (5487-12 798) µmol kg−1] than during central venous lactate infusion [4530 (3903-5514) µmol kg−1, P<0.05]. At a similar hepatic lactate delivery (∼400 µmol kg−1 min−1), hepatic lactate uptake [mean and standard deviation (sd)] was higher during portal [118 (sd 55) µmol kg−1 min−1] than during central venous lactate infusion [44 (12) µmol kg−1 min−1, P<0.05]. Time courses of arterial lactate concentrations and lactate uptake at other measured regions were similar in both groups. Conclusions Higher hepatic lactate uptake during portal compared with central venous lactate infusion at a similar total hepatic lactate influx underlines the role of portal vein lactate concentration in total hepatic lactate uptake capacity. Arterial lactate concentration does not depend on the site of lactate infusion. At higher arterial lactate concentrations, all regions participated in lactate uptak

    Effects of prolonged endotoxemia on liver, skeletal muscle and kidney mitochondrial function

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    INTRODUCTION: Sepsis may impair mitochondrial utilization of oxygen. Since hepatic dysfunction is a hallmark of sepsis, we hypothesized that the liver is more susceptible to mitochondrial dysfunction than the peripheral tissues, such as the skeletal muscle. We studied the effect of prolonged endotoxin infusion on liver, muscle and kidney mitochondrial respiration and on hepatosplanchnic oxygen transport and microcirculation in pigs. METHODS: Twenty anesthetized pigs were randomized to receive either endotoxin or saline infusion for 24 hours. Muscle, liver and kidney mitochondrial respiration was assessed. The cardiac output (thermodilution) and the carotid, superior mesenteric and kidney arterial, portal venous (ultrasound Doppler) and microcirculatory blood flow (laser Doppler) were measured, and systemic and regional oxygen transport and lactate exchange were calculated. RESULTS: Endotoxin infusion induced hyperdynamic shock and impaired the glutamate-dependent and succinate-dependent mitochondrial respiratory control ratio in the liver (glutamate, median (range) endotoxemia 2.8 (2.3–3.8) vs controls 5.3 (3.8–7.0); P < 0.001; succinate, endotoxemia 2.9 (1.9–4.3) vs controls 3.9 (2.6–6.3), P = 0.003). While the ADP added/oxygen consumed ratio was reduced with both substrates, the maximal ATP production was impaired only in the succinate-dependent respiration. Hepatic oxygen consumption and extraction, and the liver surface laser Doppler blood flow remained unchanged. Glutamate-dependent respiration in the muscle and kidney was unaffected. CONCLUSION: Endotoxemia reduces the efficiency of hepatic mitochondrial respiration but neither skeletal muscle nor kidney mitochondrial respiration, independent of regional and microcirculatory blood flow changes

    Systematic review of analgesics and dexamethasone for post-tonsillectomy pain in adults

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    Background: Intense pain can last several days after tonsillectomy. It is often undertreated and improved analgesic strategies that can be safely used at home are needed. Methods: We conducted a systematic review and meta-analysis on the effectiveness of systemic medications used for post-tonsillectomy pain in adult and adolescent (13 yr old) patients. Studies were identified from PubMed, the Cochrane Library, and by hand searching reference lists from studies and review articles. Randomised, double-blind, placebo-controlled studies reporting on pain intensity or use of rescue analgesia were included. Results: Twenty-nine randomised controlled trials representing 1816 subjects met the inclusion criteria. Follow-up time was Conclusions: Single analgesics and dexamethasone provide only a weak to moderate effect for post-tonsillectomy pain on the day of operation and thus a multimodal analgesic strategy is recommended. Short follow-up times and clinical heterogeneity of studies limit the usefulness of results.Peer reviewe

    An integrated hardware/software design methodology for signal processing systems

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    This paper presents a new methodology for design and implementation of signal processing systems on system-on-chip (SoC) platforms. The methodology is centered on the use of lightweight application programming interfaces for applying principles of dataflow design at different layers of abstraction. The development processes integrated in our approach are software implementation, hardware implementation, hardware-software co-design, and optimized application mapping. The proposed methodology facilitates development and integration of signal processing hardware and software modules that involve heterogeneous programming languages and platforms. As a demonstration of the proposed design framework, we present a dataflow-based deep neural network (DNN) implementation for vehicle classification that is streamlined for real-time operation on embedded SoC devices. Using the proposed methodology, we apply and integrate a variety of dataflow graph optimizations that are important for efficient mapping of the DNN system into a resource constrained implementation that involves cooperating multicore CPUs and field-programmable gate array subsystems. Through experiments, we demonstrate the flexibility and effectiveness with which different design transformations can be applied and integrated across multiple scales of the targeted computing system

    Regional brain morphometry in patients with traumatic brain injury based on acute- and chronic-phase magnetic resonance imaging.

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    Traumatic brain injury (TBI) is caused by a sudden external force and can be very heterogeneous in its manifestation. In this work, we analyse T1-weighted magnetic resonance (MR) brain images that were prospectively acquired from patients who sustained mild to severe TBI. We investigate the potential of a recently proposed automatic segmentation method to support the outcome prediction of TBI. Specifically, we extract meaningful cross-sectional and longitudinal measurements from acute- and chronic-phase MR images. We calculate regional volume and asymmetry features at the acute/subacute stage of the injury (median: 19 days after injury), to predict the disability outcome of 67 patients at the chronic disease stage (median: 229 days after injury). Our results indicate that small structural volumes in the acute stage (e.g. of the hippocampus, accumbens, amygdala) can be strong predictors for unfavourable disease outcome. Further, group differences in atrophy are investigated. We find that patients with unfavourable outcome show increased atrophy. Among patients with severe disability outcome we observed a significantly higher mean reduction of cerebral white matter (3.1%) as compared to patients with low disability outcome (0.7%)
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