Comparative radio-opacity of bones of commonly consumed fish species in western Kenya region on digitalised lateral neck X-ray films

Objective: To determine the comparative radio-opacity on digital plain radiographs of bones of 10 fish species commonly consumed in Western Kenya Region.Design: Descriptive cross sectional study.Setting: Jaramogi Oginga Teaching and Referral Hospital, Kisumu Kenya.Results: There was excellent interobserver agreement on the rating of 21out of 25 films evaluated. The overall sensitivity of plain radiographs in detection of raw and cooked fish bones was 72% and 69% respectively but varied significantly between fish species. The specificity of the technique was 100% overall.Conclusion: Lateral soft tissue neck radiograph is an appropriate screening tool in cases of a suspected impacted fishbone. If a fishbone is identified on a radiograph, the patient should be referred for endoscopy without further imaging. If the radiograph is normal, then there should be no further imaging or endoscopy. An observation policy can be adopted. Radiographs may be of limited value in cases of Butter fish (Schilbe intermedius) and Elephant snout fish (Momuruscarnume) bone impaction as these bones are radiolucent. In such cases, further imaging by CT scan or endoscopy without further imaging may be recommended when clinically indicated

The Silver Cyprinid Rastrineobola Argentea as the main diet source for rearing Anopheles arabiensis mosquitoes

Background & objectives: All organisms that are cultured for laboratory bioassays need food for sustenance and amplification of the colony to such numbers that would not compromise the progress of the research at hand. For effective turnover rate in the population generation, the diet should be such that it is readily available and provide adequate nutrients to the organisms. The aim of this study was to test and evaluate the efficacy of Rastrineobola argentea as a diet source for rearing Anopheles arabiensis Patton mosquitoes for research. Methods: Crushed fish, Rastrineobola argentea and two other commercial larval feeds (Tetramin Baby fish food and baker’s yeast) were compared for their efficacy as diet sources for feeding Anopheles arabiensis mosquito larvae. The effects of these diet types were determined against fecundity, size, longevity and male mating competitiveness. Results: Mosquitoes raised on Tetramin Baby fish food laid larger egg batches (66.45 ± 5.03 mm) as compared to crushed fish (64.86 ± 4.93 mm) or bakers’ yeast (50.49 ± 4.25 mm). However, the number of eggs laid by the mosquitoes irrespective of the diet type did no differ significantly (p < 0.132). Mosquitoes raised on Tetramin Baby fish food were larger in size (3.06 ± 0.02 mm) as compared to those raised on crushed R. argentea (2.93 ± 0.01 mm) or baker’s yeast (3.00 ± 0.02 mm). The choice of diet was found to influence both mosquito size (p < 0.001) and fecundity (p < 0.013). Conclusion: This study found that crushed R. argentea is an effective mosquito larval diet and that it has the potential of being more effective than tetramin if refined further and supplements added. Keywords Rastrineobola argentea; Anopheles arabiensis; Fecundity; Longevity; Eclosio

The Global Financial Crisis, Inflation Rate And Stock Market Returns In Kenya

The moderating effect of events such as the 2008 Global Financial Crisis (GFC) on the relation between stock market returns and macroeconomic variables has attracted very little attention. This study investigates the extent to which the 2008 GFC moderated the relationship between inflation rate and stock market returns. The study uses month-onmonth inflation rate and year-on-year inflation rate from 1st January 1993 to 31st December 2015 and divides the sample data into pre-crisis period (from 1st January 1993 to 31st December 2007); crisis period (from 1st January 2008 to 30th June 2009); and post-crisis period (from 1st July 2009 to 31st December 2015). It uses a product-term regression model instead of the most widely applied additive regression model. Results indicate that a unit increase in the both measures of inflation rate had significant depressing effects on stock market returns after the crisis compared to before the crisis. Likewise, the results reveal that average stock market returns were significantly higher after the crisis compared to before the crisis at low rather than medium or high values of the two measures of inflation rate. These results suggest that the Kenyan stock market is highly sensitive to variations in inflation rate, especially as it emerges from a financial or political turmoil. This study is empirically innovative in the sense that it is the first to examine the moderating effect of the 2008 GFC on the relation between inflation rate and stock market returns in Kenya using a product-term model

Leveraging Farmer Field Days to Provide Family Planning and Other Health Services in Rural Kenya

Background: Access to family planning (FP) and other reproductive health (RH) services is difficult in much of rural Africa. Distance to health facilities, staff shortages, stock-outs, and other barriers impede the uptake and continued use of contraception. One way to improve FP access in rural areas is to deliver FP services at non-health events. FHI and Land O’Lakes collaborated to assess a model for providing health services through existing farmer-education events.  This study examined the introduction of Family Planning/Reproductive Health services through Land O’Lakes-supported dairy cooperatives. Methods: The study was conducted at seven events in Central and Rift Valley provinces between August and December 2010. Typical field days draw attendees from across the dairy sector: farmers, processors, development partners and officials from the Ministry of Livestock Development and the Kenya Dairy Board. At each study site, local Land O Lakes and dairy cooperative staff helped to incorporate a “family health camp” where attendees could consult with clinicians. The package included FP services, child immunizations, antenatal care, sexually transmitted infection screening and treatment, and HIV counseling and testing. All women, 18 to 49 years old, who received services from an on-site provider, were invited to participate in a survey about the health camp and the offered services. A total of 319 women were interviewed. Key findings: Use of health services at the seven field days was high; more than 80% of the 2,344 attendees received consultations. The services provided most frequently during the field-days were non-reproductive health exams (66%), FP counseling (18%), and HIV counseling and testing (13%). Of the women interviewed, 40% were affiliated with a dairy cooperative. One-quarter of current FP users acquired additional supplies of contraceptives at the event.  Knowledge contributions: This study contributes to the scant data regarding the provision of health services in the non-health sector. . This model provides a convenient way for rural people to access health services. Key Words: FP services, non-health sector, rural area, farmer

Risk mapping of Rinderpest sero-prevalence in Central and Southern Somalia based on spatial and network risk factors

The Somali livestock production system is oriented towards domestic trade and export with seasonal movement patterns of herds/flocks in search of water and pasture and towards export points. The objective of the study is to develop a predictive spatial model of presence of rinderpest.Habka loo diyaariyo xoola soomaliyeed ee loogu talagalay in lagu iibiyo dalka gudihiisa ama dibaddiisa, iyagoo xoolahaas loo kaxaynaayo hadba meeshi biyo iyo baad leh iyo goobtii laga dhoofinayaba. Qasdiga daraasaadkaani wuxuu yahay sidii loo hormarin lahaa habka looga hortegi lahaa cudurrada faafa ee lo'da.Il sistema di produzione di bestiame somalo è orientato verso il commercio interno e l'esportazione con movimenti stagionali delle mandrie/greggi in cerca di acqua e pascoli e verso i luoghi di esportazione. L'obiettivo dello studio è quello di sviluppare un modello spaziale predittivo della presenza di peste bovina

Risk mapping of Rinderpest sero-prevalence in Central and Southern Somalia based on spatial and network risk factors

<p>Abstract</p> <p>Background</p> <p>In contrast to most pastoral systems, the Somali livestock production system is oriented towards domestic trade and export with seasonal movement patterns of herds/flocks in search of water and pasture and towards export points. Data from a rinderpest survey and other data sources have been integrated to explore the topology of a contact network of cattle herds based on a spatial proximity criterion and other attributes related to cattle herd dynamics. The objective of the study is to integrate spatial mobility and other attributes with GIS and network approaches in order to develop a predictive spatial model of presence of rinderpest.</p> <p>Results</p> <p>A spatial logistic regression model was fitted using data for 562 point locations. It includes three statistically significant continuous-scale variables that increase the risk of rinderpest: home range radius, herd density and clustering coefficient of the node of the network whose link was established if the sum of the home ranges of every pair of nodes was equal or greater than the shortest distance between the points. The sensitivity of the model is 85.1% and the specificity 84.6%, correctly classifying 84.7% of the observations. The spatial autocorrelation not accounted for by the model is negligible and visual assessment of a semivariogram of the residuals indicated that there was no undue amount of spatial autocorrelation. The predictive model was applied to a set of 6176 point locations covering the study area. Areas at high risk of having serological evidence of rinderpest are located mainly in the coastal districts of Lower and Middle Juba, the coastal area of Lower Shabele and in the regions of Middle Shabele and Bay. There are also isolated spots of high risk along the border with Kenya and the southern area of the border with Ethiopia.</p> <p>Conclusions</p> <p>The identification of point locations and areas with high risk of presence of rinderpest and their spatial visualization as a risk map will be useful for informing the prioritization of disease surveillance and control activities for rinderpest in Somalia. The methodology applied here, involving spatial and network parameters, could also be applied to other diseases and/or species as part of a standardized approach for the design of risk-based surveillance activities in nomadic pastoral settings.</p

Co2 exchange and biomass development of the herbaceous vegetation in the portuguese montado ecosystem during spring

Montado are spatially heterogeneous ecosystems that are economically important for the production of cork and herbaceous biomass that provide fodder for animals. Understanding of how trees and the herbaceous layer interact to determine pasture yield and the overall CO2 exchange of the herbaceous layer is crucial. Portable chamberswere used to study CO2 exchange by the herbaceous layer component of the montado ecosystem in southern Portugal. Biomass, Net herbaceous layer CO2 exchange (NEE) and respiration (Reco) were measured in the open and understory locations between March and May, during the active growing period. Parameter fits on the NEE data were performed using empirical hyperbolic light response model, while ecosystem respiration (Reco) data were fitted with a two-parameter exponential model. Annual green biomass productions were 405.8 9.0 and 250.6 6.3 g m 2 in the open and the understory, respectively. The respective maximum NEE during the day were 24.0 2.9 and 9.6 2.2 mmol m 2 s 1 while maximum Reco were 20.6 2.2 and 10.0 1.6 mmol m 2 s 1, occurring in April. Photosynthetic photon flux density (PPFD) explained more that 70% of variations in daytime NEE while soil temperature at 10 cm depth (Tsoil) explained >50% of the variations in Reco under non-limiting soil moisture conditions. Both the herbaceous layer communities shared similar plant functional types and no significant difference in nutrient nitrogen (N) occurred between them. The two herbaceous layer components shared similar physiological characteristics and differences that arose in their CO2 uptake capacities and green biomass production were the result of microclimatic differences created by tree shadin

Whole-genome sequencing in an autism multiplex family

BACKGROUND: Autism spectrum disorders (ASDs) represent a group of childhood neurodevelopmental disorders that affect 1 in 88 children in the US. Previous exome sequencing studies on family trios have implicated a role for rare, de-novo mutations in the pathogenesis of autism. METHODS: To examine the utility of whole-genome sequencing to identify inherited disease candidate variants and genes, we sequenced two probands from a large pedigree, including two parents and eight children. We evaluated multiple analytical strategies to identify a prioritized list of candidate genes. RESULTS: By assuming a recessive model of inheritance, we identified seven candidate genes shared by the two probands. We also evaluated a different analytical strategy that does not require the assumption of disease model, and identified a list of 59 candidate variants that may increase susceptibility to autism. Manual examination of this list identified ANK3 as the most likely candidate gene. Finally, we identified 33 prioritized non-coding variants such as those near SMG6 and COQ5, based on evolutionary constraint and experimental evidence from ENCODE. Although we were unable to confirm rigorously whether any of these genes indeed contribute to the disease, our analysis provides a prioritized shortlist for further validation studies. CONCLUSIONS: Our study represents one of the first whole-genome sequencing studies in autism leveraging a large family-based pedigree. These results provide for a discussion on the relative merits of finding de-novo mutations in sporadic cases versus finding inherited mutations in large pedigrees, in the context of neuropsychiatric and neurodevelopmental diseases