FLEXOB - Entwicklungstool für dynamische, modellbasierte CAD-Systeme

Objektorientierte Modellierungstechniken werden gegenwärtig vor allem Entwicklern von CAD-Systemen angeboten. Sie erzeugen über die Schritte OO-Modellanalyse und OO-Softwaredesign OO-Programme, die mit ihrer Compilation das durch den Softwareingenieur gefundene Modell festschreiben. Generell, aber insbesondere im Bauwerksdesign, ist dieses Vorgehen unbefriedigend, da hier eine Normung von Modellen nicht gelingt, der Entwurfsprozeß vergleichsweise lang ist und eine Kooperation von Ingenieurgewerken mit verschiedenen Modelldomänen die Regel sind. Darüber hinaus weisen die Modelle in frühen Phasen ein hohes Maß an Unschärfe und Abstraktion auf. CAD-Tools, die diese Phasen unterstützen, benötigen deshalb: statt eines genormten Produktmodells ein einheitliches, kognitiv begründetes Modellstrukturierungsparadigma, für das mit der Objektorientierung eine mögliche Ausprägung gegeben ist, ein explizites, verfügbares Domänenmodell zur fortwährenden Interpretation von Bauwerksmodellen, deskriptive Elemente, die die Interpretation von Objekten und Attributen erleichtern, ein Konzept zur Behandlung von Unschärfe und Abstraktion. Hieraus ergeben sich für die Entwicklung von CAD-Systemen folgende Forderungen : Explizite Verfügbarkeit von Klassenobjekten und deren Erzeugung und Veränderung zur Laufzeit, Vererbung auf Klassen- und Instanzniveau, Erweiterte Attributkonzepte (Facetten), Unterstützung der Aggregation als einer wesentlichen Modellstrukturierungsrelation, Verfügbarkeit von OO-Schnittstellen zum Aufbau von CAD-Systemen aus Tools einerseits, sowie zur Trennung von Modellverwaltung und Modellrepräsentation andererseits. Als ein herausragendes Merkmal des Objektorientierten Paradigmas wird die Anwendungsnähe genannt, da Erscheinungen der behandelten Domäne sich analog in Modellen und Programmen wiederfinden (sollen). Unter der Grundannahme, daß dieses Paradigma auch durch den Anwender zur Erstellung seiner Modellwelten verwendet wird, will FLEXOB eine homogene Umgebung schaffen, die die Modellwelt des Softwareingenieurs zu Analysezwecken dem Anwender zur Verfügung stellt und die die Erweiterung dieser Modellwelt auf deskriptivem Niveau ermöglicht. Das Tool FLEXOB und einige wesentliche Implementationsdetails werden im Beitrag vorgestellt. Es handelt sich bei diesem Tools um eine C++ Klassenbibliothek, die entweder als Objektmodul oder als Windows-DLL verwendet werden kann. Aspekte des Nutzungsregimes solch flexibler Modellverwaltungen werden im Beitrag ebenfalls angespochen

Optimization-based calibration of hydrodynamic drag coefficients for a semisubmersible platform using experimental data of an irregular sea state

For the simulation of the coupled dynamic response of floating offshore wind turbines, it is crucial to calibrate the hydrodynamic damping with experimental data. The aim of this work is to find a set of hydrodynamic drag coefficients for the semisubmersible platform of the Offshore Code Comparison Collaboration, Continuation, with Correlation and unCertainity (OC6) project which provides suitable results for an irregular sea state. Due to the complex interaction of several degrees of freedom (DOF), it is common to calibrate drag coefficients with the time series of decay tests. However, applying these drag coefficients for the simulation of an irregular sea state results in misprediction of the motions. By using numerical optimization, it is possible to calibrate multiple drag coefficients simultaneously and effectively, while also considering several DOF. This work considers time series of structural displacements from wave tank tests of the OC6 project and from simulations of the same load cases in OpenFAST. Results are transferred into the frequency domain and the deviation between power spectral densities of surge, pitch and heave from experiment and numerical simulation is used as an objective function to obtain the best fitting drag coefficients. This novel numerical optimization approach enables finding one set of drag coefficients for different load cases, which is a major improvement compared to decay-test-tuned drag coefficients. © Published under licence by IOP Publishing Ltd

HOPS: Automated detection and authentication of pathogen DNA in archaeological remains

High-throughput DNA sequencing enables large-scale metagenomic analyses of complex biological systems. Such analyses are not restricted to present day environmental or clinical samples, but can also be fruitfully applied to molecular data from archaeological remains (ancient DNA), and a focus on ancient bacteria can provide valuable information on the long-term evolutionary relationship between hosts and their pathogens. Here we present HOPS (Heuristic Operations for Pathogen Screening), an automated bacterial screening pipeline for ancient DNA sequence data that provides straightforward and reproducible information on species identification and authenticity. HOPS provides a versatile and fast pipeline for high-throughput screening of bacterial DNA from archaeological material to identify candidates for subsequent genomic-level analyses

Resonant forcing of select degrees of freedom of multidimensional chaotic map dynamics

We study resonances of multidimensional chaotic map dynamics. We use the calculus of variations to determine the additive forcing function that induces the largest response, that is, the greatest deviation from the unperturbed dynamics. We include the additional constraint that only select degrees of freedom be forced, corresponding to a very general class of problems in which not all of the degrees of freedom in an experimental system are accessible to forcing. We find that certain Lagrange multipliers take on a fundamental physical role as the efficiency of the forcing function and the effective forcing experienced by the degrees of freedom which are not forced directly. Furthermore, we find that the product of the displacement of nearby trajectories and the effective total forcing function is a conserved quantity. We demonstrate the efficacy of this methodology with several examples.Comment: 11 pages, 3 figure

Modified Blalock Taussig shunt: a not-so-simple palliative procedure

OBJECTIVES Thirty-two consecutive isolated modified Blalock Taussig (BT) shunts performed in infancy since 2004 were reviewed and analysed to identify the risk factors for shunt intervention and mortality. METHODS Sternotomy was the only approach used. Median age and weight were 10.5 (range 1-74) days and 2.9 (1.9-4.4) kg, respectively. Shunt palliation was performed for biventricular hearts (Tetralogy of Fallot/double outlet right ventricle/transposition of great arteries_ventricular septal defect_pulmonary stenosis/pulmonary atresia_ventricular septal defect/others) in 21, and univentricular hearts in 11, patients. Hypoplastic left heart syndrome patients were excluded. Two procedures required cardiopulmonary bypass. Median shunt size was 3.5 (3-4) mm and median shunt size/kg body weight was 1.2 (0.9-1.7) mm/kg. Reduction in shunt size was necessary in 5 of 32 (16%) patients. RESULTS Three of 32 (9%) patients died after 3 (1-15) days due to cardiorespiratory decompensation. Lower body weight (P = 0.04) and bigger shunt size/kg of body weight (P = 0.004) were significant risk factors for mortality. Acute shunt thrombosis was observed in 3 of 32 (9%), none leading to death. Need for cardiac decongestive therapy was associated with univentricular hearts (P < 0.001), bigger shunt size (P = 0.054) and longer hospital stay (P = 0.005). Twenty-eight patients have undergone a successful shunt takedown at a median age of 5.5 (0.5-11.9) months, without late mortality. CONCLUSIONS Palliation with a modified BT shunt continues to be indicated despite increased thrust on primary corrective surgery. Though seemingly simple, it is associated with significant morbidity and mortality. Effective over-shunting and acute shunt thrombosis are the lingering problems of shunt therap

Large-scale distributions of tropospheric nitric, formic, and acetic acids over the western Pacific basin during wintertime

We report here measurements of the acidic gases nitric (HNO3), formic (HCOOH), and acetic (CH3COOH) over the western Pacific basin during the February-March 1994 Pacific Exploratory Mission-West (PEM-West B). These data were obtained aboard the NASA DC-8 research aircraft as it flew missions in the altitude range of 0.3–12.5 km over equatorial regions near Guam and then further westward encompassing the entire Pacific Rim arc. Aged marine air over the equatorial Pacific generally exhibited mixing ratios of acidic gases \u3c100 parts per trillion by volume (pptv). Near the Asian continent, discrete plumes encountered below 6 km altitude contained up to 8 parts per billion by volume (ppbv) HNO3 and 10 ppbv HCOOH and CH3COOH. Overall there was a general correlation between mixing ratios of acidic gases with those of CO, C2H2, and C2Cl4, indicative of emissions from combustion and industrial sources. The latitudinal distributions of HNO3 and CO showed that the largest mixing ratios were centered around 15°N, while HCOOH, CH3COOH, and C2Cl4 peaked at 25°N. The mixing ratios of HCOOH and CH3COOH were highly correlated (r2 = 0.87) below 6 km altitude, with a slope (0.89) characteristic of the nongrowing season at midlatitudes in the northern hemisphere. Above 6 km altitude, HCOOH and CH3COOH were marginally correlated (r2 = 0.50), and plumes well defined by CO, C2H2, and C2Cl4 were depleted in acidic gases, most likely due to scavenging during vertical transport of air masses through convective cloud systems over the Asian continent. In stratospheric air masses, HNO3 mixing ratios were several parts per billion by volume (ppbv), yielding relationships with O3 and N2O consistent with those previously reported for NOy

An investigation of the chemistry of ship emission plumes during ITCT 2002

A ship emission plume experiment was conducted about 100 km off the California coast during the NOAA Intercontinental Transport and Chemical Transformation (ITCT) 2K2 airborne field campaign. Measurements of chemical species were made from the NOAA WP-3D aircraft in eight consecutive transects of a ship plume around midday during 2.5 hours of flight. The measured species include NOx, HNO3, peroxyacetylnitrate (PAN), SO2, H2SO4, O3, CO, CO2, nonmethane hydrocarbons (NMHC), and particle number and size distributions. Observations demonstrate a NOx lifetime of ∼1.8 hours inside the ship plume compared to ∼6.5 hours (at noontime) in the moderately polluted background marine boundary layer of the experiment. This confirms the earlier hypothesis of highly enhanced in-plume NOx destruction. Consequently, one would expect the impact of ship emissions is much less severe than those predicted by global models that do not include rapid NOx destruction. Photochemical model calculations suggest that more than 80% of the NOx loss was due to the NO2 + OH reaction; the remainder was by PAN formation. The model underestimated in-plume NOx loss rate by about 30%. In addition, a comparison of measured to predicted H2SO4 in the plumes suggests that the photochemical model predicts OH variability reasonably well but may underestimate actual values. Predictions of in-plume O3 production agree well with the observations, suggesting that model-predicted peroxy radical (HO2 + RO2) levels are reasonable. The model estimated ozone production efficiency ranges from 6 to 30. The largest model bias was seen in the comparison with measured HNO3. The model overestimated in-plume HNO3 by about a factor of 6. This is most likely caused by underestimated HNO3 sinks possibly involving particle scavenging. However, limited data availability precluded a conclusive test of this possible loss process. Copyright 2005 by the American Geophysical Union

Chemical composition of air masses transported from Asia to the U.S. West coast during ITCT 2K2: Fossil fuel combustion versus biomass-burning signatures

As part of the Intercontinental Transport and Chemical Transformation experiment in 2002 (ITCT 2K2), a National Oceanic and Atmospheric Administration (NOAA) WP-3D research aircraft was used to study the long-range transport of Asian air masses toward the west coast of North America. During research flights on 5 and 17 May, strong enhancements of carbon monoxide (CO) and other species were observed in air masses that had been transported from Asia. The hydrocarbon composition of the air masses indicated that the highest CO levels were related to fossil fuel use. During the flights on 5 and 17 May and other days, the levels of several biomass-buming indicators increased with altitude. This was true for acetonitrile (CH3CN), methyl chloride (CH3Cl), the ratio of acetylene (C2H2) to propane (C3H8), and, on May 5, the percentage of particles measured by the particle analysis by laser mass spectrometry (PALMS) instrument that were attributed to biomass burning based on their carbon and potassium content. An ensemble of back-trajectories, calculated from the U.S. west coast over a range of latitudes and altitudes for the entire ITCT 2K2 period, showed that air masses from Southeast Asia and China were generally observed at higher altitudes than air from Japan and Korea. Emission inventories estimate the contribution of biomass burning to the total emissions to be low for Japan and Korea, higher for China, and the highest for Southeast Asia. Combined with the origin of the air masses versus altitude, this qualitatively explains the increase with altitude, averaged over the whole ITCT 2K2 period, of the different biomass-burning indicators. Copyright 2004 by the American Geophysical Union