312 research outputs found

    Efecto de los soportes plantares con alargo de quinto radio en el tratamiento del niño con marcha en intraversión

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    A elaboração deste trabalho está enquadrado no plano de estudos do Mestrado em PodiatriaInfantil, ministrado pela ESSVA (Escola Superior de saúde do Vale do Ave do IPSN (Intituto Politécnico de Saúde Norte), e, ao abrigo de um programa ERASMUS do IPSN foi desenvolvido nas instalações da “Clínica del Pie Martín Gutiérrez” como centro adstrito ao Hospital Podológico da Universidade de Barcelona (UB) O estágio decorreu no período compreendido entre 16 de novembro de 2020 a 30 de abril de 2021, totalizando 630 horas. Ao longo desse período foram também comtemplados seminários e orientações tutorais enquadradas no plano de estudos. Este trabalho está organizado em 2 partes, uma inicial relativa ao relatório das atividades de estágio, o qual evidencia uma caracterização das atividades desenvolvidas ao longo do estágio na Clínica Martín Gutiérrez, bem uma análise critica das aprendizagens. Na segunda parte é apresentado um trabalho de investigação, cujo objetivo principal foi analisar o efeito do uso de Suportes Plantares com prolongamnto do 5º raio no tratamento da marcha em intraversão em crianças

    Características radiológicas encontradas en las cardiopatías congénitas en pacientes de 0 a 5 años evaluados por angiotomografía computada. Instituto Nacional de Salud del Niño. Breña año 2016

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    Publicación a texto completo no autorizada por el autorDetermina las características radiológicas encontradas en las cardiopatías congénitas de pacientes de 0 a 5 años evaluados por angiotomografía computada en el Instituto Nacional de Salud del Niño de Breña atendidos en el año 2016. La investigación es de tipo observacional, descriptivo, retrospectivo, transversal, con enfoque cuantitativo. Participan 63 historias clínicas de pacientes con cardiopatías congénitas que se realizan una angiotomografía computada de corazón y grandes vasos. La técnica utilizada es el análisis documental, obteniéndose los datos de las historias clínicas y de los informes angiotomográficos siendo procesados en SPSS versión 22.0. Asimismo, se realiza un análisis univariado estimándose frecuencias absolutas y relativas. Los resultados revelan que las características radiológicas observadas son: origen de la aorta de lado izquierdo (66.7%), luz conservada (82.5%); presencia de estenosis de la arteria pulmonar (82.5%), luz de arteria pulmonar conservada (55.6%); cuatro venas pulmonares (93.7%), luz de la venas pulmonares conservadas (85.7%); persistencia del ductus arterioso (49.2%); la aurícula derecha (79.4%) e izquierda (82.5%) conservadas; ventrículo derecho aumentado (50.8%) y ventrículo izquierdo conservado (65.1%). Los tipos de cardiopatías congénitas más frecuentes son atresia pulmonar (23.8%) y tetralogía de Fallot (15.9%) para cardiopatías cianóticas; y comunicación interventricular (44.4%) y persistencia del ductus arterioso (42.9%) para las cardiopatías acianóticas.Tesi

    The role of Spanish health libraries in scientific publication

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    Health libraries have been established as publication support services. Despite its importance, there is currently no study about the services that these centers offer. The aim of this work is to understand the role that libraries play in institutional scientific publishing policies. The sample was taken from the National Catalogue of Hospitals, the list of libraries of the Catalogue of Periodicals in Spanish Health Sciences Libraries (c17) and the National Catalogue of Health Sciences Publications (CNCS). Subsequently, virtual health libraries have also been incorporated. From this list, a questionnaire about library staff and activities related to publication process was sent. We obtained a participation rate of 61.21%. The average number of technical personnel was 1.15 in virtual libraries and 0.81 in hospital libraries. The activities carried out have been: training activities (82.2%), counselling (90.1%), dissemination (30.7%) and evaluation (50.5%). The staff in libraries are insufficient. In many cases technicians assume an overwork of serving in both (virtual and hospital libraries). Most libraries offer training and research support services although there are differences between virtual and hospital ones. There is a relationship between the number of technicians and the publication support services

    Simple Sequence Repeat Markers Reveal Genetic Diversity and Population Structure of Bolivian Wild and Cultivated Tomatoes (Solanum lycopersicum L.)

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    The western part of South America is a centre of diversity for tomatoes, but genetic diversity studies are lacking for parts of that region, including Bolivia. We used 11 simple sequence repeat (SSR) markers (including seven novel markers) to evaluate genetic diversity and population structure of 28 accessions (four modern cultivars, four advanced lines, nine landraces, 11 wild populations), and to compare their genetic variation against phenotypic traits, geographical origin and altitude. In total, 33 alleles were detected across all loci, with 2-5 alleles per locus. The top three informative SSRs were SLM6-11, LE20592 and TomSatX11-1, with polymorphism information content (PIC) of 0.65, 0.55 and 0.49, respectively. The genetic diversity of Bolivian tomatoes was low, as shown by mean expected heterozygosity (He) of 0.07. Analysis of molecular variance (AMOVA) revealed that 77.3% of the total variation was due to variation between accessions. Significant genetic differentiation was found for geographical origin, cultivation status, fruit shape, fruit size and growth type, each explaining 16-23% of the total variation. Unweighted Pair Group Method with Arithmetic Mean (UPGMA) tree and principal coordinate analysis (PCoA) scatter plot both revealed differentiation between accessions with determinate flowers and accessions with indeterminate flowers, regardless of cultivation status. The genetic profiles of the accessions suggest that the Bolivian tomato gene pool comprises both strictly self-pollinating and open-pollinating genotypes

    Assessing Creativity In Engineering Students: A Comparative Between Degrees and Sudents In First And Last Year

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    An online open access test (CREAX self-assessment) has been used in this work so that students from degrees in engineering in the Universidad Polite¿cnica of Madrid (UPM) could self-assess their creative competence after several classroom activities. Different groups from the first year course have been statistically compared using data from their assessment. These first year students had different professors in the subject ?Technical Drawing? and belonged to several degrees in the UPM. They were as well compared regarding sex and a group of first year students was also compared to another last year group of the degree so as to observe possible differences in the achievement of this competence. Only one difference was detected concerning sex in one of the degrees. Among degrees, the higher marks obtained by students who had done specific exercises for the development of creativity in class is highlighted. Finally, a significantly high mark was observed in students during their last year of degree with respect to first year students. The tool CREAX has become very useful in the assessment of this competence in the UPM degrees in which it has been implemented

    Teaching practice for subject of graphic expression through project based learning

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    Comunicación presentada en el XXIII International Conference on Graphic Engineering- Madrid 2013.Project-based learning PBL (Aprendizaje Basado en Proyectos, ABP) is a participatory methodology which foments skills demanded by the company, in addition to being a teaching strategy which helps to achieve competence in the subjects of graphic expression at/in the different degrees of industrial engineering. This article presents the design, development, analysis and evaluation of results obtained in a project of computer-aided design, based on PBL, aimed to students in electrical engineering degree from Polytechnic School of Malaga during the biennium 2008/2010, developed in the educational innovation project, PIE08-056.PIE08-05

    Manganese Inhalation as a Parkinson Disease Model

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    The present study examines the effects of divalent and trivalent Manganese (Mn2+/Mn3+) mixture inhalation on mice to obtain a novel animal model of Parkinson disease (PD) inducing bilateral and progressive dopaminergic cell death, correlate those alterations with motor disturbances, and determine whether L-DOPA treatment improves the behavior, to ensure that the alterations are of dopaminergic origin. CD-1 male mice inhaled a mixture of Manganese chloride and Manganese acetate, one hour twice a week for five months. Before Mn exposure, animals were trained to perform motor function tests and were evaluated each week after the exposure. By the end of Mn exposure, 10 mice were orally treated with 7.5 mg/kg L-DOPA. After 5 months of Mn mixture inhalation, striatal dopamine content decreased 71%, the SNc showed important reduction in the number of TH-immunopositive neurons, mice developed akinesia, postural instability, and action tremor; these motor alterations were reverted with L-DOPA treatment. Our data provide evidence that Mn2+/Mn3+ mixture inhalation produces similar morphological, neurochemical, and behavioral alterations to those observed in PD providing a useful experimental model for the study of this neurodegenerative disease

    The impact of CD160 deficiency on alloreactive CD8 T cell responses and allograft rejection

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    .CD160 is a member of the immunoglobulin superfamily with a pattern of expression mainly restricted to cytotoxic cells. To assess the functional relevance of the HVEM/CD160 signaling pathway in allogeneic cytotoxic responses, exon 2 of the CD160 gene was targeted by CRISPR/Cas9 to generate CD160 deficient mice. Next, we evaluated the impact of CD160 deficiency in the course of an alloreactive response. To that aim, parental donor WT (wild-type) or CD160 KO (knock-out) T cells were adoptively transferred into non-irradiated semiallogeneic F1 recipients, in which donor alloreactive CD160 KO CD4 T cells and CD8 T cells clonally expanded less vigorously than in WT T cell counterparts. This differential proliferative response rate at the early phase of T cell expansion influenced the course of CD8 T cell differentiation and the composition of the effector T cell pool that led to a significant decreased of the memory precursor effector cells (MPECs) / short-lived effector cells (SLECs) ratio in CD160 KO CD8 T cells compared to WT CD8 T cells. Despite these differences in T cell proliferation and differentiation, allogeneic MHC class I mismatched (bm1) skin allograft survival in CD160 KO recipients was comparable to that of WT recipients. However, the administration of CTLA-4.Ig showed an enhanced survival trend of bm1 skin allografts in CD160 KO with respect to WT recipients. Finally, CD160 deficient NK cells were as proficient as CD160 WT NK cells in rejecting allogeneic cellular allografts or MHC class I deficient tumor cells. CD160 may represent a CD28 alternative costimulatory molecule for the modulation of allogeneic CD8 T cell responses either in combination with costimulation blockade or by direct targeting of alloreactive CD8 T cells that upregulate CD160 expression in response to alloantigen stimulation.S

    Delirium en pacientes con trauma craneoencefálico del Hospital Universitario San Jorge, EPS

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    El trauma craneoencefálico (TEC) es cualquier alteración física o deterioro funcional del contenido craneal, secundario a un cambio brusco de energía mecánica, siendo una de sus complicaciones más frecuentes el Delirium, un síndrome neuropsiquiátrico cuyos síntomas esenciales incluyen deterioro cognitivo, alteración de la atención, el afecto y el comportamiento, que aparece súbitamente y tiene un curso fluctuante. Este estudio descriptivo incluyó 28 pacientes ingresados al Hospital San Jorge con diagnóstico de TEC durante los meses de marzo y abril de 2007, evaluados con escalas para detectar delirium. Se encontró que el 46% presentó Delirium en algún momento de su estadía hospitalaria, siendo mayor la incidencia en quienes presentaron TEC moderado y durante los primeros días de su hospitalización
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