Molecular Docking Studies for the Assessment of Wound Healing Activity of Phytoconstituents in Heliotropium Indicum

One of the most crucial and complex processes is the skin's multi-stage process of healing after an injury. Heliotropium indicum is a potent antibiotic, anti- inflammatory, anti-neoplastic, anti-oxidant, and wound- healing agent. Heliotropium indicum Linn is the source of the chemical compound in question, which is abundant in sterols, ammines, volatile oils, and the pyrrolizidine alkaloids. Molecular docking studies were conducted on Heliotropium indicum using Argus lab 4.0.1 and Autodock 1.5.7. The proteins PDB ID:1YXO, 3V18, and 4G8R were selected because of their role in wound healing. The pieces work together with the protein responsible for mending wounds. The binding affinities of mupirocin and nitrofurazone are higher than those of the components stigmasterol, eugenol, borneol, and campesterol. In order to better customize Heliotropium indicum to our requirements, we now have a better knowledge of the components of the molecule that interact with their receptors in the wound healing process

Review of Waste Cooking Oil (WCO) as a Feedstock for Biofuel—Indian Perspective

A detailed review was conducted to explore waste cooking oil (WCO) as feedstock for biodiesel. The manuscript highlights the impact on health while using used cooking oil and the scope for revenue generation from WCO. Up to a 20% blend with diesel results in less pollutants, and it does not demand more modifications to the engine. Also, this reduces the country’s import bill. Furthermore, it suggests the scope for alternate sustainable income among rural farmers through a circular economy. Various collection strategies are discussed, a SWOC (strength, weakness, opportunity, and challenges) analysis is presented to aid in understanding different countries’ policies regarding the collection of WCO, and a more suitable method for conversion is pronounced. A techno-economic analysis is presented to explore the viability of producing 1 litre of biodiesel. The cost of 1 litre of WCO-based biodiesel is compared with costs Iran and Pakistan, and it is noticed that the difference among them is less than 1%. Life cycle assessment (LCA) is mandatory to reveal the impact of WCO biodiesel on socio-economic and environmental concerns. Including exergy analysis will provide comprehensive information about the production and justification of WCO as a biodiesel

Experimental analysis of solar air heater using polygonal ribs in absorber plate integrated with phase change material

Heat transfer enhancement in solar air heater has been investigated by implementing rough surfaces in the absorber plate. We use paraffin wax is used as phase change material integrated with solar air heater as a thermal energy storage system. A maximum convective heat transfer is attained during the daytime and retained as latent heat to discharge heat during OFF radiation. In this investigation, two types of absorber plates were employed such as flat and polygonal-shaped ribs at the test section. Further to investigate the heat transfer enhancement, the research was conducted with and without phase change material. The study was carried out at the mass-flow rates of 0.062 kg/s, 0.028 kg/s, and 0.01 kg/s to ascertain the enhancement of thermal efficiency and heat discharge duration. The temperatures of absorber plate, Tp, ambient Tamb, outlet, Tout, and phase change material along with solar intensity, I [Wm–2], were taken as the main parameters. The research reveals that the absorber plate with polygonal ribs tested with phase change material yields a higher temperature of 77°C with a mass-flow rate of 0.062 kg/s during peak radiation. Discharged heat energy from phase change material to absorber plate for 3.5 hours with a maximum temperature of 7.1°C