435 research outputs found
Water Ice and Dust in the Innermost Coma of Comet 103P/Hartley 2
On November 4th, 2010, the Deep Impact eXtended Investigation (DIXI)
successfully encountered comet 103P/Hartley 2, when it was at a heliocentric
distance of 1.06 AU. Spatially resolved near-IR spectra of comet Hartley 2 were
acquired in the 1.05-4.83 micron wavelength range using the HRI-IR
spectrometer. We present spectral maps of the inner ~10 kilometers of the coma
collected 7 minutes and 23 minutes after closest approach. The extracted
reflectance spectra include well-defined absorption bands near 1.5, 2.0, and
3.0 micron consistent in position, bandwidth, and shape with the presence of
water ice grains. Using Hapke's radiative transfer model, we characterize the
type of mixing (areal vs. intimate), relative abundance, grain size, and
spatial distribution of water ice and refractories. Our modeling suggests that
the dust, which dominates the innermost coma of Hartley 2 and is at a
temperature of 300K, is thermally and physically decoupled from the
fine-grained water ice particles, which are on the order of 1 micron in size.
The strong correlation between the water ice, dust, and CO2 spatial
distribution supports the concept that CO2 gas drags the water ice and dust
grains from the nucleus. Once in the coma, the water ice begins subliming while
the dust is in a constant outflow. The derived water ice scale-length is
compatible with the lifetimes expected for 1-micron pure water ice grains at 1
AU, if velocities are near 0.5 m/s. Such velocities, about three order of
magnitudes lower than the expansion velocities expected for isolated 1-micron
water ice particles [Hanner, 1981; Whipple, 1951], suggest that the observed
water ice grains are likely aggregates.Comment: 51 pages, 12 figures, accepted for publication in Icaru
Spitzer observations of the asteroid-comet transition object and potential spacecraft target 107P (4015) Wilson-Harrington
Context. Near-Earth asteroid-comet transition object 107P/ (4015)
Wilson-Harrington is a possible target of the joint European Space Agency (ESA)
and Japanese Aerospace Exploration Agency (JAXA) Marco Polo sample return
mission. Physical studies of this object are relevant to this mission, and also
to understanding its asteroidal or cometary nature. Aims. Our aim is to obtain
significant new constraints on the surface thermal properties of this object.
Methods. We present mid-infrared photometry in two filters (16 and 22 microns)
obtained with NASA's Spitzer Space Telescope on February 12, 2007, and results
from the application of the Near Earth Asteroid Thermal Model (NEATM).We
obtained high S/N in two mid-IR bands allowing accurate measurements of its
thermal emission. Results. We obtain a well constrained beaming parameter (eta
= 1.39 +/- 0.26) and obtain a diameter and geometric albedo of D = 3.46 +/-
0.32 km, and pV = 0.059 +/- 0.011. We also obtain similar results when we apply
this best-fitting thermal model to single-band mid-IR photometry reported by
Campins et al. (1995), Kraemer et al. (2005) and Reach et al. (2007).
Conclusions. The albedo of 4015 Wilson-Harrington is low, consistent with those
of comet nuclei and primitive C-, P-, D-type asteorids. We establish a rough
lower limit for the thermal inertia of W-H of 60 Jm^-2s^(-0.5)K^-1 when it is
at r=1AU, which is slightly over the limit of 30 Jm^-2s^(-0.5)K-1 derived by
Groussin et al. (2009) for the thermal inertia of the nucleus of comet
22P/Kopff.Comment: 4 pages, 1 figure and 3 tables. Paper accepted for publicatio
Exploring the surface properties of Transneptunian Objects and Centaurs with polarimetric FORS1/VLT observations
Polarization is a powerful remote-sensing method to investigate solar system
bodies. It is an especially sensitive diagnostic tool to reveal physical
properties of the bodies whose observational characteristics are governed by
small scatterers (dust, regolith surfaces). For these objects, at small phase
angles, a negative polarization is observed, i.e., the electric vector E
oscillates predominantly in the scattering plane, contrary to what is typical
for rather smooth homogeneous surfaces. The behavior of negative polarization
with phase angle depends on the size, composition and packing of the
scatterers. These characteristics can be unveiled by modelling the light
scattering by the dust or regolith in terms of the coherent backscattering
mechanism.
We have investigated the surface properties of TNOs and Centaurs by means of
polarimetric observations with FORS1 of the ESO VLT.
TNOs Ixion and Quaoar, and Centaur Chiron show a negative polarization surge.
The Centaur Chiron has the deepest polarization minimum (-1.5 - 1.4%). The two
TNOs show differing polarization curves: for Ixion, the negative polarization
increases rapidly with phase; for Quaoar, the polarization is relatively small
(~ -0.6%), and nearly constant at the observed phase angles. For all three
objects, modelling results suggest that the surface contains an areal mixture
of at least two components with different single-scatterer albedos and photon
mean-free paths.Comment: 11 pages, 7 postscript figures, accepted by A&A; astro-ph abstract
has been replaced with a more complete on
Shape modeling technique KOALA validated by ESA Rosetta at (21) Lutetia
We present a comparison of our results from ground-based observations of
asteroid (21) Lutetia with imaging data acquired during the flyby of the
asteroid by the ESA Rosetta mission. This flyby provided a unique opportunity
to evaluate and calibrate our method of determination of size, 3-D shape, and
spin of an asteroid from ground-based observations. We present our 3-D
shape-modeling technique KOALA which is based on multi-dataset inversion. We
compare the results we obtained with KOALA, prior to the flyby, on asteroid
(21) Lutetia with the high-spatial resolution images of the asteroid taken with
the OSIRIS camera on-board the ESA Rosetta spacecraft, during its encounter
with Lutetia. The spin axis determined with KOALA was found to be accurate to
within two degrees, while the KOALA diameter determinations were within 2% of
the Rosetta-derived values. The 3-D shape of the KOALA model is also confirmed
by the spectacular visual agreement between both 3-D shape models (KOALA pre-
and OSIRIS post-flyby). We found a typical deviation of only 2 km at local
scales between the profiles from KOALA predictions and OSIRIS images, resulting
in a volume uncertainty provided by KOALA better than 10%. Radiometric
techniques for the interpretation of thermal infrared data also benefit greatly
from the KOALA shape model: the absolute size and geometric albedo can be
derived with high accuracy, and thermal properties, for example the thermal
inertia, can be determined unambiguously. We consider this to be a validation
of the KOALA method. Because space exploration will remain limited to only a
few objects, KOALA stands as a powerful technique to study a much larger set of
small bodies using Earth-based observations.Comment: 15 pages, 8 figures, 2 tables, accepted for publication in P&S
p.Ala541Thr variant of MEN1 gene: A non deleterious polymorphism or a pathogenic mutation?
Context
Multiple Endocrine Neoplasia Type 1 (MEN1) is an autosomal dominant inherited syndrome, related to mutations in the MEN1 gene. Controversial data suggest that the nonsynonymous p.Ala541Thr variant, usually considered as a non-pathogenic polymorphism, may be associated with an increased risk of MEN1-related lesions in carriers.
Objective
The aim of this study was to evaluate the pathogenic influence of the p.Ala541Thr variant on clinical and functional outcomes.
Patients and methods
We analysed a series of 55 index patients carrying the p.Ala541Thr variant. Their clinical profile was compared to that of 117 MEN1 patients. The biological impact of the p.Ala541Thr variant on cell growth was additionally investigated on menin-deficient Leydig cell tumour (LCT)10 cells generated from Men1+/Men1− heterozygous knock-out mice, and compared with wild type (WT).
Results
The mean age at first appearance of endocrine lesions was similar in both p.Ala541Thr carriers and MEN1 patients, but no p.Ala541Thr patient had more than one cardinal MEN1 lesion at initial diagnosis. A second MEN1 lesion was diagnosed in 13% of MEN1 patients and in 7% of p.Ala541Thr carriers in the year following preliminary diagnosis. Functional studies on LCT10 cells showed that overexpression of the p.Ala541Thr variant did not inhibit cell growth, which is in direct contrast to results obtained from investigation of WT menin protein.
Conclusion
Taken together, these data raise the question of a potential pathogenicity of the p.Ala541Thr missense variant of menin that commonly occurs within the general population. Additional studies are required to investigate whether it may be involved in a low-penetrance MEN1 phenotype
THERMAP: a mid-infrared spectro-imager for space missions to small bodies in the inner solar system
We present THERMAP, a mid-infrared (8-16 μm) spectro-imager for space missions to small bodies in the inner solar system, developed in the framework of the MarcoPolo-R asteroid sample return mission. THERMAP is very well suited to characterize the surface thermal environment of a NEO and to map its surface composition. The instrument has two channels, one for imaging and one for spectroscopy: it is both a thermal camera with full 2D imaging capabilities and a slit spectrometer. THERMAP takes advantage of the recent technological developments of uncooled microbolometers detectors, sensitive in the mid-infrared spectral range. THERMAP can acquire thermal images (8-18 μm) of the surface and perform absolute temperature measurements with a precision better than 3.5 K above 200 K. THERMAP can acquire mid-infrared spectra (8-16 μm) of the surface with a spectral resolution Δλ of 0.3 μm. For surface temperatures above 350 K, spectra have a signal-to-noise ratio >60 in the spectral range 9-13 μm where most emission features occur
Shape, Density, and Geology of the Nucleus of Comet 103P/Hartley 2
Data from the Extrasolar Planet Observation and Deep Impact Extended Investigation (EPOXI) mission show Comet 103P/Hartley 2 is a bi-lobed, elongated, nearly axially symmetric comet 2.33 km in length. Surface features are primarily small mounds 1%. The shape may be the evolutionary product of insolation, sublimation, and temporary deposition of materials controlled by the objects complex rotation
Bio++: Efficient Extensible Libraries and Tools for Computational Molecular Evolution
Efficient algorithms and programs for the analysis of the ever-growing amount of biological sequence data are strongly needed in the genomics era. The pace at which new data and methodologies are generated calls for the use of pre-existing, optimized—yet extensible—code, typically distributed as libraries or packages. This motivated the Bio++ project, aiming at developing a set of C++ libraries for sequence analysis, phylogenetics, population genetics, and molecular evolution. The main attractiveness of Bio++ is the extensibility and reusability of its components through its object-oriented design, without compromising the computer-efficiency of the underlying methods. We present here the second major release of the libraries, which provides an extended set of classes and methods. These extensions notably provide built-in access to sequence databases and new data structures for handling and manipulating sequences from the omics era, such as multiple genome alignments and sequencing reads libraries. More complex models of sequence evolution, such as mixture models and generic n-tuples alphabets, are also included
The rotation state of 67P/Churyumov-Gerasimenko from approach observations with the OSIRIS cameras on Rosetta
Aims. Approach observations with the Optical, Spectroscopic, and Infrared Remote Imaging System (OSIRIS) experiment onboard Rosetta are used to determine the rotation period, the direction of the spin axis, and the state of rotation of comet 67P's nucleus. Methods. Photometric time series of 67P have been acquired by OSIRIS since the post wake-up commissioning of the payload in March 2014. Fourier analysis and convex shape inversion methods have been applied to the Rosetta data as well to the available ground-based observations. Results. Evidence is found that the rotation rate of 67P has significantly changed near the time of its 2009 perihelion passage, probably due to sublimation-induced torque. We find that the sidereal rotation periods P1 = 12.76129 ± 0.00005 h and P2 = 12.4043 ± 0.0007 h for the apparitions before and after the 2009 perihelion, respectively, provide the best fit to the observations. No signs of multiple periodicity are found in the light curves down to the noise level, which implies that the comet is presently in a simple rotation state around its axis of largest moment of inertia. We derive a prograde rotation model with spin vector J2000 ecliptic coordinates λ = 65° ± 15°, β = + 59° ± 15°, corresponding to equatorial coordinates RA = 22°, Dec = + 76°. However, we find that the mirror solution, also prograde, at λ = 275° ± 15°, β = + 50° ± 15° (or RA = 274°, Dec = + 27°), is also possible at the same confidence level, due to the intrinsic ambiguity of the photometric problem for observations performed close to the ecliptic plane
Regional unit definition for the nucleus of comet 67P/Churyumov-Gerasimenko on the SHAP7 model
The previously defined regions on the nucleus of comet 67P/Churyumov-Gerasimenko have been mapped back onto the 3D SHAP7 model of the nucleus (Preusker et al., 2017). The resulting regional definition is therefore self-consistent with boundaries that are well defined in 3 dimensions. The facets belonging to each region are provided as supplementary material. The shape model has then been used to assess inhomogeneity of nucleus surface morphology within individual regions. Several regions show diverse morphology. We propose sub-division of these regions into clearly identifiable units (sub-regions) and a comprehensive table is provided. The surface areas of each sub-region have been computed and statistics based on grouping of unit types are provided. The roughness of each region is also provided in a quantitative manner using a technique derived from computer graphics applications. The quantitative method supports the sub-region definition by showing that differences between sub-regions can be numerically justified
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