Measurement of Cosmic Shear with the Space Telescope Imaging Spectrograph

Weak lensing by large-scale structure allows a direct measure of the dark matter distribution. We have used parallel images taken with the Space Telescope Imaging Spectrograph (STIS) on the Hubble Space Telescope to measure weak lensing, or cosmic shear. We measure the shapes of 26036 galaxies in 1292 STIS fields and measure the shear variance at a scale of 0.51 arcminutes. The charge transfer efficiency (CTE) of STIS has degraded over time and introduces a spurious ellipticity into galaxy shapes during the readout process. We correct for this effect as a function of signal to noise and CCD position. We further show that the detected cosmic shear signal is nearly constant in time over the approximately four years of observation. We detect cosmic shear at the 5.1 sigma level, and our measurement of the shear variance is consistent with theoretical predictions in a LambdaCDM universe. This provides a measure of the normalization of the mass power spectrum sigma_8=(1.02 +- 0.16) (0.3/Omega_m)^{0.46} (0.21/Gamma)^{0.18}$. The one-sigma error includes noise, cosmic variance, systematics and the redshift uncertainty of the source galaxies. This is consistent with previous cosmic shear measurements, but tends to favor those with a high value of sigma_8. It is also consistent with the recent determination of sigma_8 from the Wilkinson Microwave Anisotropy Probe (WMAP) experiment.Comment: 9 pages, 5 figure, 1 table, Accepted to Ap

Inflammation and Oral Contraceptive Use in Female Athletes Before the Rio Olympic Games

This study investigated the association between synthetic ovarian hormone use [i.e., the oral contraceptive (OC) pill] and basal C-reactive protein (CRP), peripheral blood immune cell subsets, and circulating pro- and anti-inflammatory cytokine concentrations in elite female athletes. Elite female athletes (n = 53) selected in Rio Summer Olympic squads participated in this study; 25 were taking an OC (AthletesOC) and 28 were naturally hormonally cycling (AthletesNC). Venous blood samples were collected at rest for the determination of sex hormones, cortisol, CRP, peripheral blood mononuclear memory and naïve CD4+ T-cells, CD8+ T-cells and natural killer cells, as well as pro- and anti-inflammatory cytokine concentrations. C-reactive protein concentrations were elevated (p < 0.001) in AthletesOC (median = 2.02, IQR = 3.15) compared to AthletesNC (median = 0.57, IQR = 1.07). No differences were reported for cortisol, cytokines, or PBMC immune cell subsets, although there was a trend (p = 0.062) for higher IL-6 concentrations in AthletesNC. Female Olympians had substantially higher CRP concentrations, a marker of inflammation and tissue damage, before the Rio Olympic Games if they used an OC. Future research should examine the potential consequences for athlete performance/recovery so that, if necessary, practitioners can implement prevention programs

Functional conservation of the Drosophila hybrid incompatibility gene Lhr

<p>Abstract</p> <p>Background</p> <p>Hybrid incompatibilities such as sterility and lethality are commonly modeled as being caused by interactions between two genes, each of which has diverged separately in one of the hybridizing lineages. The gene <it>Lethal hybrid rescue </it>(<it>Lhr</it>) encodes a rapidly evolving heterochromatin protein that causes lethality of hybrid males in crosses between <it>Drosophila melanogaster </it>females and <it>D. simulans </it>males. Previous genetic analyses showed that hybrid lethality is caused by <it>D. simulans Lhr </it>but not by <it>D. melanogaster Lhr</it>, confirming a critical prediction of asymmetry in the evolution of a hybrid incompatibility gene.</p> <p>Results</p> <p>Here we have examined the functional properties of <it>Lhr </it>orthologs from multiple Drosophila species, including interactions with other heterochromatin proteins, localization to heterochromatin, and ability to complement hybrid rescue in <it>D. melanogaster</it>/<it>D. simulans </it>hybrids. We find that these properties are conserved among most <it>Lhr </it>orthologs, including <it>Lhr </it>from <it>D. melanogaster</it>, <it>D. simulans </it>and the outgroup species <it>D. yakuba</it>.</p> <p>Conclusions</p> <p>We conclude that evolution of the hybrid lethality properties of <it>Lhr </it>between <it>D. melanogaster </it>and <it>D. simulans </it>did not involve extensive loss or gain of functions associated with protein interactions or localization to heterochromatin.</p

Investor Psychology and Security Market Under- and Overreactions

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73431/1/0022-1082.00077.pd

Acute effects of parainfluenza virus on epithelial electrolyte transport

Parainfluenza viruses are important causes of respiratory disease in both children and adults. In particular, they are the major cause of the serious childhood illness croup (laryngotracheobronchitis). The infections produced by parainfluenza viruses are associated with the accumulation of ions and fluid in the respiratory tract. It is not known, however, whether this accumulation is because of a direct effect of the viruses on ion and fluid transport by the respiratory epithelium. Here we show that a model parainfluenza virus (the Sendai virus), in concentrations observed during respiratory infections, activates Cl- secretion and inhibits Na+ absorption across the tracheal epithelium. It does so by binding to a neuraminidase-insensitive glycolipid, possibly asialo-GM1, triggering the release of ATP, which then acts in an autocrine fashion on apical P2Y receptors to produce the observed changes in ion transport. These findings indicate that fluid accumulation in the respiratory tract associated with parainfluenza virus infection is attributable, at least in part, to direct effects of the virus on ion transport by the respiratory epithelium

Does applying humic acids with fall fertilizer increase yield and/or affect soil and crop nutrient contents in a corn (Zea Mays L.) and soybean (Glycine Max L. Merr) rotation?

The application of the humic product Hydra-Hume DG A "Coated" at 10 lb A-1 with fall fertilizer in a corn and soybean rotation did not have significant effects on yield of corn and soybean, or significantly increase soil nutrient availability or crop nutrient uptake in this field study conducted in West Bend, WI. This study was conducted using commercial equipment in a commercial field. This study was composed of six replicated, strip trials consisting of a control which was the normal fall fertilizer practice, and and humic treatment which was the normal fall fertilizer practice plus 10 lb A-1 of Hydra Hume DG A "Coated". The data collected consisted of yield data, soil test data, and tissue nutrient concentration data. The study was conducted over four years of a corn-soybean rotation beginning in 2017 and ending in 2020

AIDS - Dr. Paul Cameron (discredited psychologist)

Copies of a letter and two newspaper clippings discussing Paul Cameron's false claims and distorted citations that he used to unjustly link homosexuality to pedophilia

MOESM1 of Whole-genome sequence of an evolved Clostridium pasteurianum strain reveals Spo0A deficiency responsible for increased butanol production and superior growth

Additional file 1. Table S1: Nucleotide sequence variants from published data. Table S2: Sequence and features of pDcm2.0 with codon optimized Cpa bepIM. Figure S1: Phase-contrast microscopy of WT and M150B after 6 days. Phase-bright forespores observed in the WT and the asporogenous phenotype is apparent in the M150B strain. Figure S2: Whole genome SMRT sequencing coverage depth overage across reference. Cpa wild type ATCC 6013 and Cpa mutant M150B coverage across the reference genome. Figure S3: Cultures of the wild type, M150B, and ΔSpo0A Cpa strains after 5 days culturing. Cultures were allowed to rest without agitation. M150B cultures consistently settled quickly compared to wild type, while the ΔSpo0A consistently remained in suspension longer than the wild type. This shows the M150B phenotype is not due to the Spo0A deficiency