1,958 research outputs found
Narrative in design development
This paper describes the value of narrative used with ideation tools in aiding the rapid production of product concepts and designs for masters students of graphics, fine art, product and industrial design. The ideation tools used alongside narrative included elements of divergent and convergent thinking in combination with reverse engineering and functional analysis, and practical prototyping using a range of readily adapted artefacts. Narrative was introduced and used by the students in order to ensure the development of a context and purpose for the product, artefact or system developed or proposed and to stimulate original product concepts, ideas and thinking. The concept of narrative is familiar in design. Here however the concept was reinforced using structures associated with fictional narrative. Reverse engineering exploring the deconstruction and identification of function for each component in a product was used to aid students ensure practicality in their idea implementation. This paper describes positive experiences resulting from this activity, with a particular focus on the value of narrative in developing robust concepts. The use of physical prototyping provided tangible and instant feedback for divergent and convergent phases of idea development
Sodium and Water Fluxes in Free-Living Crocodylus Porosus in Marine and Brackish Conditions
Radioactive sodium and water were used to determine total body water (TBW), exchangeable sodium (ExNa) and water and sodium fluxes in free-living Crocodylus porosus in marine (hyperosmotic; salinity = 250/00-350/00) and brackish (hypoosmotic; salinity = 20/00-7.50/00) sections of the Tomkinson River in northern Australia. At capture, size-corrected TBW and ExNa pools in 62 crocodiles (hatchlings, juveniles, and subadults; weight, 0.108-54.4 kg) were independent of salinity history. To determine fluxes, all animals were released at their capture sites and left undisturbed until recapture. Thirty-seven were recaptured after 7-18 days. Fifteen of the 17 hatchlings recaptured from both salinity categories grew and maintained their condition and hydration status. In contrast, all 20 juveniles and subadults lost weight in the same period, and juveniles in hyperosmotic conditions showed significantly lower hydration and condition factors. Water effluxes in hatchlings were ~80 and ~160 ml kg-0.63 day-1 in marine and brackish conditions, respectively. Comparable sodium effluxes were 7.5 and 4.4 mmol kg-0.63 day1. All crocodiles in hyperosmotic conditions had consistently lower water effluxes (~ X0.5) and higher sodium effluxes (~ X 1.6) than did crocodiles in brackish water. In both salinity categories, hatchlings had greater water turnover (~ X 1.3, X 1.6) and sodium turnover (~ X 1.5, X 1.25) than did juveniles and subadults. Interpretation of the field data is complicated by integumentary exchange of sodium and water, a size-related aphagia apparently induced by disturbance, and difficulties of adjusting for allometric differences across a wide range of sizes. Nevertheless, it is clear that C. porosus is able to effect considerable economies of water turnover in hyperosmotic salt water and that the secretory capacity of the lingual glands, as measured in the laboratory, is more than enough to account for the highest sodium effluxes that we measured in C. porosus in the field
Recommended from our members
Factors influencing the utilisation of free-standing and alongside midwifery units in England: a qualitative research study
OBJECTIVE: To identify factors influencing the provision, utilisation and sustainability of midwifery units (MUs) in England.
DESIGN: Case studies, using individual interviews and focus groups, in six National Health Service (NHS) Trust maternity services in England.
SETTING AND PARTICIPANTS: NHS maternity services in different geographical areas of England Maternity care staff and service users from six NHS Trusts: two Trusts where more than 20% of all women gave birth in MUs, two Trusts where less than 10% of all women gave birth in MUs and two Trusts without MUs. Obstetric, midwifery and neonatal clinical leaders, managers, service user representatives and commissioners were individually interviewed (n=57). Twenty-six focus groups were undertaken with midwives (n=60) and service users (n=52).
MAIN OUTCOME MEASURES: Factors influencing MU use.
FINDINGS: The study findings identify several barriers to the uptake of MUs. Within a context of a history of obstetric-led provision and lack of decision-maker awareness of the clinical and economic evidence, most Trust managers and clinicians do not regard their MU provision as being as important as their obstetric unit (OU) provision. Therefore, it does not get embedded as an equal and parallel component in the Trust's overall maternity package of care. The analysis illuminates how implementation of complex interventions in health services is influenced by a range of factors including the medicalisation of childbirth, perceived financial constraints, adequate leadership and institutional norms protecting the status quo.
CONCLUSIONS: There are significant obstacles to MUs reaching their full potential, especially free-standing midwifery units. These include the lack of commitment by providers to embed MUs as an essential service provision alongside their OUs, an absence of leadership to drive through these changes and the capacity and willingness of providers to address women's information needs. If these remain unaddressed, childbearing women's access to MUs will continue to be restricted
Comparative Erythrocyte Metabolism in Marsupials and Monotremes
Concentrations of ATP and DPG, activities of 10 enzymes and the glycolytic rates were measured in the erythrocytes of 11 species of marsupials and two species of monotremes. Mean DPG concentrations were greater in the erythrocytes of marsupials than those of eutherian mammals. The opposite is true of ATP. Significant findings from the results of enzyme activities were: high activity of hexokinase (7.39 + 0.82 EU/g Hb) in the short-beaked echidna, pyruvate kinase (37.49 + 1.0 EU/g) Hb in bridled nailtail wallaby and glucose-6-phosphate dehydrogenase (G6PD; 41.66 + 1.24 EU/g Rb) in black-striped wallaby. About 6- to 7-fold difference in the activity of G6PD levels between the two species of wombats was confirmed. Glucose phosphate isomerase activity was also shown to be twice as high in the red cells of the common wombat compared with those of the southern hairy nosed wombat. There were wide variations in the glycolytic rate among the species examined
Facultative Aestivation in a Tropical Freshwater Turtle Chelodina rugosa
Abstract-1. Chelodina rugosa dug from aestivation sites at the end of the dry season were immediately alert and well coordinated. 2. Compared with non-aestivating animals, aestivating turtles had 20% higher plasma osmotic pressure and 7% higher sodium. Coupled with a small, but significant weight gain upon return to the water, this suggested the occurrence of minor dehydration in aestivating animals. 3. Plasma lactate levels of aestivating animals were low, averaging 1.99 mmol/1, consistent with aerobic rather than anaerobic metabolism having sustained their long period under ground. 4. No evidence was seen of dramatic physiological specialization. Aestivation in this species is interpreted as a primarily behavioural adaptation, made possible by typically reptilian abilities to tolerate a wide range in plasma electrolytes and to survive long periods without feeding
The nonlocal model of porewater irrigation: Limits to its equivalence with a cylinder diffusion model
Burrows maintained by animals in aquatic sediments ventilate the sediment and can substantially alter the rates and pathways of biologically-mediated decomposition reactions. A well known and effective way of modeling the impact of such bioirrigation in sediment diagenetic models is to assume that solutes diffuse into an annulus of sediment surrounding the burrow; the reaction diffusion equations are represented in cylindrical polar co-ordinates. More commonly, bioirrigation of sediments is represented by one-dimensional nonlocal irrigation models. Their use is typically justified by the assertion that a nonlocal model is equivalent to a radially-integrated two-dimensional diffusion model in cylindrical-polar co-ordinates. In this paper we highlight limits to this equivalence, drawing on examples from both single-species and multiple-species reaction diffusion models. A modified derivation of the nonlocal model using a higher order Taylor series approximation was tested but found to provide little improvement over the original model. We suggest some approaches for choosing nonlocal coefficients and identify particular limitations to be alert to when applying the nonlocal model
Women’s experiences of transfer from primary maternity unit to tertiary hospital in New Zealand: part of the prospective cohort Evaluating Maternity Units study
BACKGROUND: There is worldwide debate regarding the appropriateness and safety of different birthplaces for well women. The Evaluating Maternity Units (EMU) study’s primary objective was to compare clinical outcomes for well women intending to give birth in either a tertiary level maternity hospital or a freestanding primary level maternity unit. Little is known about how women experience having to change their birthplace plans during the antenatal period or before admission to a primary unit, or transfer following admission. This paper describes and explores women’s experience of these changes-a secondary aim of the EMU study. METHODS: This paper utilised the six week postpartum survey data, from the 174 women from the primary unit cohort affected by birthplace plan change or transfer (response rate 73 %). Data were analysed using descriptive statistics and thematic analysis. The study was undertaken in Christchurch, New Zealand, which has an obstetric-led tertiary maternity hospital and four freestanding midwife-led primary maternity units (2010–2012). The 702 study participants were well, pregnant women booked to give birth in one of these facilities, all of whom received continuity of midwifery care, regardless of their intended or actual birthplace. RESULTS: Of the women who had to change their planned place of birth or transfer the greatest proportion of women rated themselves on a Likert scale as unbothered by the move (38.6 %); 8.8 % were ‘very unhappy’ and 7.6 % ‘very happy’ (quantitative analysis). Four themes were identified, using thematic analysis, from the open ended survey responses of those who experienced transfer: ‘not to plan’, control, communication and ‘my midwife’. An interplay between the themes created a cumulatively positive or negative effect on their experience. Women’s experience of transfer in labour was generally positive, and none expressed stress or trauma with transfer. CONCLUSIONS: The women knew of the potential for change or transfer, although it was not wanted or planned. When they maintained a sense control, experienced effective communication with caregivers, and support and information from their midwife, the transfer did not appear to be experienced negatively. The model of continuity of midwifery care in New Zealand appeared to mitigate the negative aspects of women’s experience of transfer and facilitate positive birth experiences
A PHABULOSA/cytokinin feedback loop controls root growth in arabidopsis
The hormone cytokinin (CK) controls root length in Arabidopsis thaliana by defining where dividing cells, derived from stem cells of the root meristem, start to differentiate [ [1], [2], [3], [4], [5] and [6]]. However, the regulatory inputs directing CK to promote differentiation remain poorly understood. Here, we show that the HD-ZIPIII transcription factor PHABULOSA (PHB) directly activates the CK biosynthesis gene ISOPENTENYL TRANSFERASE 7 (IPT7), thus promoting cell differentiation and regulating root length. We further demonstrate that CK feeds back to repress both PHB and microRNA165, a negative regulator of PHB. These interactions comprise an incoherent regulatory loop in which CK represses both its activator and a repressor of its activator. We propose that this regulatory circuit determines the balance of cell division and differentiation during root development and may provide robustness against CK fluctuations
A Taxonomic Revision Of The Litoria aurea Complex (Anura: Hylidae) In South-Eastern Australia
Four subspecies of Litoria aurea have been previously recognised in south-eastern Australia. In the present paper, it is proposed that two of these subspecies (Litoria aurea aurea and Litoria aurea raniformis) be raised to specific status as Litoria aurea and Litoria raniformis respectively; that an isolated population from the New England region of NSW be recognised as a new species Litoria flavipunctata; and that the remaining two subspecies, Litoria aurea ulongae and Litoria aurea major be synonymised with Litoria aurea and Litoria raniformia respectively. This revision in taxonomy is proposed on the basis of morphological evidence and the apparent lack of hybridisation in areas of sympatry
- …