The SCUBA Half Degree Extragalactic Survey (SHADES) - III : Identification of radio and mid-infrared counterparts to submillimetre galaxies

Peer reviewe

Evaluating 35 Methods to Generate Structural Connectomes Using Pairwise Classification

There is no consensus on how to construct structural brain networks from diffusion MRI. How variations in pre-processing steps affect network reliability and its ability to distinguish subjects remains opaque. In this work, we address this issue by comparing 35 structural connectome-building pipelines. We vary diffusion reconstruction models, tractography algorithms and parcellations. Next, we classify structural connectome pairs as either belonging to the same individual or not. Connectome weights and eight topological derivative measures form our feature set. For experiments, we use three test-retest datasets from the Consortium for Reliability and Reproducibility (CoRR) comprised of a total of 105 individuals. We also compare pairwise classification results to a commonly used parametric test-retest measure, Intraclass Correlation Coefficient (ICC).Comment: Accepted for MICCAI 2017, 8 pages, 3 figure

Probing highly obscured, self-absorbed galaxy nuclei with vibrationally excited HCN

We present high resolution (0."4) IRAM PdBI and ALMA mm and submm observations of the (ultra) luminous infrared galaxies ((U)LIRGs) IRAS17208-0014, Arp220, IC860 and Zw049.057 that reveal intense line emission from vibrationally excited ($\nu_2$=1) J=3-2 and 4-3 HCN. The emission is emerging from buried, compact (r<17-70 pc) nuclei that have very high implied mid-infrared surface brightness $>$$5\times 10^{13}$ L$_{\odot}$ kpc$^{-2}$. These nuclei are likely powered by accreting supermassive black holes (SMBHs) and/or hot (>200 K) extreme starbursts. Vibrational, $\nu_2$=1, lines of HCN are excited by intense 14 micron mid-infrared emission and are excellent probes of the dynamics, masses, and physical conditions of (U)LIRG nuclei when H$_2$ column densities exceed $10^{24}$ cm$^{-2}$. It is clear that these lines open up a new interesting avenue to gain access to the most obscured AGNs and starbursts. Vibrationally excited HCN acts as a proxy for the absorbed mid-infrared emission from the embedded nuclei, which allows for reconstruction of the intrinsic, hotter dust SED. In contrast, we show strong evidence that the ground vibrational state ($\nu$=0), J=3-2 and 4-3 rotational lines of HCN and HCO$^+$ fail to probe the highly enshrouded, compact nuclear regions owing to strong self- and continuum absorption. The HCN and HCO$^+$ line profiles are double-peaked because of the absorption and show evidence of non-circular motions - possibly in the form of in- or outflows. Detections of vibrationally excited HCN in external galaxies are so far limited to ULIRGs and early-type spiral LIRGs, and we discuss possible causes for this. We tentatively suggest that the peak of vibrationally excited HCN emission is connected to a rapid stage of nuclear growth, before the phase of strong feedback.Comment: 13 pages, 7 figures, accepted for publication in Astronomy and Astrophysic

The local FIR Galaxy Colour-Luminosity distribution: A reference for BLAST, and Herschel/SPIRE sub-mm surveys

We measure the local galaxy far-infrared (FIR) 60-to-100 um colour-luminosity distribution using an all-sky IRAS survey. This distribution is an important reference for the next generation of FIR--submillimetre surveys that have and will conduct deep extra-galactic surveys at 250--500 um. With the peak in dust-obscured star-forming activity leading to present-day giant ellipticals now believed to occur in sub-mm galaxies near z~2.5, these new FIR--submillimetre surveys will directly sample the SEDs of these distant objects at rest-frame FIR wavelengths similar to those at which local galaxies were observed by IRAS. We have taken care to correct for temperature bias and evolution effects in our IRAS 60 um-selected sample. We verify that our colour-luminosity distribution is consistent with measurements of the local FIR luminosity function, before applying it to the higher-redshift Universe. We compare our colour-luminosity correlation with recent dust-temperature measurements of sub-mm galaxies and find evidence for pure luminosity evolution of the form (1+z)^3. This distribution will be useful for the development of evolutionary models for BLAST and SPIRE surveys as it provides a statistical distribution of rest-frame dust temperatures for galaxies as a function of luminosity.Comment: 12 pages, 7 figures. MNRAS in press. This revision matches final published version. Fixes typos in footnote 1 and equation 8. Minor modifications to text and references. Final results unchange

Robot-Assisted vs. Conventional Laparoscopic Rectopexy for Rectal Prolapse: A Comparative Study on Costs and Time

PURPOSE: Laparoscopic rectopexy has become one of the most advocated treatments for full-thickness rectal prolapse, offering good functional results compared with open surgery and resulting in less postoperative pain and faster convalescence. However, laparoscopic rectopexy can be technically demanding. Once having mastered dexterity, with robotic assistance, laparoscopic rectopexy can be performed faster. Moreover, it shortens the learning curve in simple laparoscopic tasks. This may lead to faster and safer laparoscopic surgery. Robot-assisted rectopexy has been proven safe and feasible; however, until now, no study has been performed comparing costs and time consumption in conventional laparoscopic rectopexy vs. robot-assisted rectopexy. METHODS: Our first 14 cases of robot-assisted laparoscopic rectopexy were reviewed and compared with 19 patients who underwent conventional laparoscopic rectopexy in the same period. RESULTS: Robot-assisted laparoscopic rectopexy did not show more complications. However, the average operating time was 39 minutes longer, and costs were 557.29 (or: $745.09) higher. CONCLUSION: Robot-assisted laparoscopic rectopexy is a safe and feasible procedure but results in increased time and higher costs than conventional laparoscopy. AD - Department of Surgery, Maastricht University Hospital, Maastricht, The Netherlands

AzTEC Millimetre Survey of the COSMOS Field - II. Source Count Overdensity and Correlations with Large-Scale Structure

We report an over-density of bright sub-millimetre galaxies (SMGs) in the 0.15 sq. deg. AzTEC/COSMOS survey and a spatial correlation between the SMGs and the optical-IR galaxy density at z <~ 1.1. This portion of the COSMOS field shows a ~ 3-sigma over-density of robust SMG detections when compared to a background, or "blankfield", population model that is consistent with SMG surveys of fields with no extragalactic bias. The SMG over-density is most significant in the number of very bright detections (14 sources with measured fluxes S(1.1mm) > 6 mJy), which is entirely incompatible with sample variance within our adopted blank-field number densities and infers an over-density significance of >> 4. We find that the over-density and spatial correlation to optical-IR galaxy density are most consistent with lensing of a background SMG population by foreground mass structures along the line of sight, rather than physical association of the SMGs with the z <~ 1.1 galaxies/clusters. The SMG positions are only weakly correlated with weak-lensing maps, suggesting that the dominant sources of correlation are individual galaxies and the more tenuous structures in the region and not the massive and compact clusters. These results highlight the important roles cosmic variance and large-scale structure can play in the study of SMGs.Comment: 12 pages, 11 figures, 2 tables, accepted for publication in MNRA

Deep 1.1 mm-wavelength imaging of the GOODS-S field by AzTEC/ASTE - I. Source catalogue and number counts

[Abridged] We present the first results from a 1.1 mm confusion-limited map of the GOODS-S field taken with AzTEC on the ASTE telescope. We imaged a 270 sq. arcmin field to a 1\sigma depth of 0.48 - 0.73 mJy/beam, making this one of the deepest blank-field surveys at mm-wavelengths ever achieved. Although our GOODS-S map is extremely confused, we demonstrate that our source identification and number counts analyses are robust, and the techniques discussed in this paper are relevant for other deeply confused surveys. We find a total of 41 dusty starburst galaxies with S/N >= 3.5 within this uniformly covered region, where only two are expected to be false detections. We derive the 1.1mm number counts from this field using both a "P(d)" analysis and a semi-Bayesian technique, and find that both methods give consistent results. Our data are well-fit by a Schechter function model with (S', N(3mJy), \alpha) = (1.30+0.19 mJy, 160+27 (mJy/deg^2)^(-1), -2.0). Given the depth of this survey, we put the first tight constraints on the 1.1 mm number counts at S(1.1mm) = 0.5 mJy, and we find evidence that the faint-end of the number counts at S(850\mu m) < 2.0 mJy from various SCUBA surveys towards lensing clusters are biased high. In contrast to the 870 \mu m survey of this field with the LABOCA camera, we find no apparent under-density of sources compared to previous surveys at 1.1 mm. Additionally, we find a significant number of SMGs not identified in the LABOCA catalogue. We find that in contrast to observations at wavelengths < 500 \mu m, MIPS 24 \mu m sources do not resolve the total energy density in the cosmic infrared background at 1.1 mm, demonstrating that a population of z > 3 dust-obscured galaxies that are unaccounted for at these shorter wavelengths potentially contribute to a large fraction (~2/3) of the infrared background at 1.1 mm.Comment: 21 pages, 9 figures. Accepted to MNRAS

The Herschel Comprehensive (U)LIRG Emission Survey (HerCULES): CO Ladders, fine structure lines, and neutral gas cooling

(Ultra) Luminous Infrared Galaxies ((U)LIRGs) are objects characterized by their extreme infrared (8-1000 $\mu$m) luminosities ($L_{LIRG}>10^{11}$L$_\odot$ and $L_{ULIRG}>10^{12}$ L$_\odot$). The Herschel Comprehensive ULIRG Emission Survey (HerCULES; PI van der Werf) presents a representative flux-limited sample of 29 (U)LIRGs that spans the full luminosity range of these objects (10$^{11}\leq L_\odot \geq10^{13}$). With the \emph{Herschel Space Observatory}, we observe [CII] 157 $\mu$m, [OI] 63 $\mu$m, and [OI] 145 $\mu$m line emission with PACS, CO J=4-3 through J=13-12, [CI] 370 $\mu$m, and [CI] 609 $\mu$m with SPIRE, and low-J CO transitions with ground-based telescopes. The CO ladders of the sample are separated into three classes based on their excitation level. In 13 of the galaxies, the [OI] 63 $\mu$m emission line is self absorbed. Comparing the CO excitation to the IRAS 60/100 $\mu$m ratio and to far infrared luminosity, we find that the CO excitation is more correlated to the far infrared colors. We present cooling budgets for the galaxies and find fine-structure line flux deficits in the [CII], [SiII], [OI], and [CI] lines in the objects with the highest far IR fluxes, but do not observe this for CO $4\leq J_{upp}\leq13$. In order to study the heating of the molecular gas, we present a combination of three diagnostic quantities to help determine the dominant heating source. Using the CO excitation, the CO J=1-0 linewidth, and the AGN contribution, we conclude that galaxies with large CO linewidths always have high-excitation CO ladders, and often low AGN contributions, suggesting that mechanical heating is important

Neurofilament light in plasma is a potential biomarker of central nervous system involvement in systemic lupus erythematosus

BACKGROUND: Neuropsychiatric manifestations (NP) are common in systemic lupus erythematosus (SLE). However, the pathophysiological mechanisms are not completely understood. Neurofilament light protein (NfL) is part of the neuronal cytoskeleton. Increased NfL concentrations, reflecting neurodegeneration, is observed in cerebrospinal fluid (CSF) in several neurodegenerative and neuroinflammatory conditions. We aimed to explore if plasma NfL could serve as a biomarker for central nervous system (CNS) involvement in SLE. METHODS: Sixty-seven patients with SLE underwent neurological examination; 52 underwent lumbar puncture, while 62 underwent cerebral magnetic resonance imaging (MRI). We measured selected auto-antibodies and other laboratory variables postulated to have roles in NP pathophysiology in the blood and/or CSF. We used SPM12 software for MRI voxel-based morphometry. RESULTS: Age-adjusted linear regression analyses revealed increased plasma NfL concentrations with increasing creatinine (β = 0.01, p < 0.001) and Q-albumin (β = 0.07, p = 0.008). We observed higher plasma NfL concentrations in patients with a history of seizures (β = 0.57, p = 0.014), impaired motor function (β = 0.36, p = 0.008), increasing disease activity (β = 0.04, p = 0.008), and organ damage (β = 0.10, p = 0.002). Voxel-based morphometry suggested an association between increasing plasma NfL concentrations and the loss of cerebral white matter in the corpus callosum and hippocampal gray matter. CONCLUSION: Increased plasma NfL concentrations were associated with some abnormal neurological, cognitive, and neuroimaging findings. However, plasma NfL was also influenced by other factors, such as damage accrual, creatinine, and Q-albumin, thereby obscuring the interpretation of how plasma NfL reflects CNS involvement. Taken together, NfL in CSF seems a better marker of neuronal injury than plasma NfL in patients with SLE

Searching for massive galaxies at z>=3.5 in GOODS-North

We constrain the space density and properties of massive galaxy candidates at redshifts of z>=3.5 in the GOODS-N field. By selecting sources in the Spitzer+IRAC bands, a highly stellar mass-complete sample is assembled,including massive galaxies which are very faint in the optical/near-IR bands that would be missed by samples selected at shorter wavelengths. The z>=3.5 sample was selected down to 23 mag at 4.5 micron using photometric redshifts that have been obtained by fitting the galaxies SEDs at optical, near-IR and IRAC bands. We also require that the brightest band in which candidates are detected is the IRAC 8 micron band in order to ensure that the near-IR 1.6 micron (rest-frame) peak is falling in or beyond this band. We found 53 z>=3.5 candidates, with masses in the range of M~10^10-10^11M_sun. At least ~81% of these galaxies are missed by traditional Lyman Break selection methods based on UV light. Spitzer+MIPS emission is detected for 60% of the sample of z>=3.5 galaxy candidates. Although in some cases this might suggest a residual contamination from lower redshift star-forming galaxies or AGN, 37% of these objects are also detected in the sub-mm/mm bands in recent SCUBA,AzTEC and MAMBO surveys, and have properties fully consistent with vigorous starburst galaxies at z>=3.5. The comoving number density of galaxies with stellar masses >= 5x10^10M_sun(a reasonable stellar mass completeness limit for our sample) is 2.6x10^-5Mpc^-3 (using the volume within 3.5<z<5), and the corresponding stellar mass density is ~2.9x10^6M_sunMpc^-3, or~3% of the local density above the same stellar mass limit.For the sub-sample of MIPS-undetected galaxies,we find a number density of ~0.97x10^-5Mpc^-3 and a stellar mass density of ~1.15x10^6M_sun Mpc^-3.[abridged]Comment: Accepted by A&A; 35 pages, 15 figures, references update