263 research outputs found
The Timing of Childbirth: Does the Age of First-Time Mothers Affect the Parental Gender Earnings Gap?
This paper assesses the impact the timing of first birth may have on the parental gender wage gap. Using data from the 2014 Survey of Income and Program Participation (SIPP), I use a pooled, cross-sectional sample of full-time parents in the United States labor force to examine the relationship between earnings and age at first birth for mothers and fathers and any relative difference that arises between the two. My findings indicate the presence of a parental gender wage gap, and that the timing of first birth can significantly impact parental wages. In addition, my results suggest that the timing of first birth impacts the earnings of mothers and fathers differently. Although having a child before age 30 lowers earnings for both mothers and fathers, the negative effect is larger for mothers. Finally, I find that the total earnings gap among mothers and fathers is larger between younger first-time parents relative to older first-time parents, and is smallest between mothers and fathers who have their first child after 35 years old
Parenthood, Professorship, and Librarianship: Are They Mutually Exclusive?
A survey of tenure-track and tenured librarians at ARL libraries provides data on the relationship between parenthood and professorship. Results analyze the impact of the promotion and tenure process on child-bearing and child-rearing decisions. Discrepancies are found based on gender, tenure status, and family status
On the Size and Comoving Mass Density Evolution of Early-Type Galaxies
We present a simple, empirically motivated model that simultaneously predicts
the evolution of the mean size and the comoving mass density of massive
early-type galaxies from z=2 to the present. First we demonstrate that some
size evolution of the population can be expected simply due to the continuous
emergence of early-type galaxies. SDSS data reveal that in the present-day
universe more compact early-type galaxies with a given dynamical mass have
older stellar populations. In contrast, at a given stellar velocity dispersion,
SDSS data show that there is no relation between size and age, which implies
that the velocity dispersion can be used to estimate the epoch at which
galaxies stopped forming stars, turning into early-type galaxies. Applying such
a 'formation' criterion to a large sample of nearby early-type galaxies, we
predict the redshift evolution in the size distribution and the comoving mass
density. The resulting evolution in the mean size is roughly half of the
observed evolution. Then we include a prescription for the merger histories of
galaxies between the 'formation' redshift and the present, based on
cosmological simulations of the assembly of dark matter halos. Such mergers
after the transformation into an early-type galaxy are presumably
dissipationless ('dry'), where the increase in size is expected to be
approximately proportional to the increase in mass. This model successfully
reproduces the observed evolution since z~2 in the mean size and in the
comoving mass density of massive early-type galaxies. We conclude that the
recently measured, substantial size evolution of early-type galaxies can be
explained by the combined effect of the continuous emergence of galaxies as
early types and their subsequent growth through dry merging.Comment: Accepted for publication in ApJ (13 pages, 5 figures), small changes
to match journal versio
Role of Fas and Treg Cells in Fracture Healing as Characterized in the Fas-Deficient (lpr) Mouse Model of Lupus
Previous studies showed that loss of tumor necrosis factor α (TNFα) signaling delayed fracture healing by delaying chondrocyte apoptosis and cartilage resorption. Mechanistic studies showed that TNFα induced Fas expression within chondrocytes; however, the degree to which chondrocyte apoptosis is mediated by TNFα alone or dependent on the induction of Fas is unclear. This question was addressed by assessing fracture healing in Fas-deficient B6.MRL/Faslpr/J mice. Loss of Fas delayed cartilage resorption but also lowered bone fraction in the calluses. The reduced bone fraction was related to elevated rates of coupled bone turnover in the B6.MRL/Faslpr/J calluses, as evidenced by higher osteoclast numbers and increased osteogenesis. Analysis of the apoptotic marker caspase 3 showed fewer positive chondrocytes and osteoclasts in calluses of B6.MRL/Faslpr/J mice. To determine if an active autoimmune state contributed to increased bone turnover, the levels of activated T cells and Treg cells were assessed. B6.MRL/Faslpr/J mice had elevated Treg cells in both spleens and bones of B6.MRL/Faslpr/J but decreased percentage of activated T cells in bone tissues. Fracture led to ∼30% to 60% systemic increase in Treg cells in both wild-type and B6.MRL/Faslpr/J bone tissues during the period of cartilage formation and resorption but either decreased (wild type) or left unchanged (B6.MRL/Faslpr/J) the numbers of activated T cells in bone. These results show that an active autoimmune state is inhibited during the period of cartilage resorption and suggest that iTreg cells play a functional role in this process. These data show that loss of Fas activity specifically in chondrocytes prolonged the life span of chondrocytes and that Fas synergized with TNFα signaling to mediate chondrocyte apoptosis. Conversely, loss of Fas systemically led to increased osteoclast numbers during later periods of fracture healing and increased osteogenesis. These findings suggest that retention of viable chondrocytes locally inhibits osteoclast activity or matrix proteolysis during cartilage resorption
Farmers' reasoning behind the uptake of agroforestry practices: evidence from multiple case-studies across Europe
Potential benefits and costs of agroforestry practices have been analysed by experts, but few studies have captured farmers’ perspectives on why agroforestry might be adopted on a European scale. This study provides answers to this question, through an analysis of 183 farmer interviews in 14 case study systems in eight European countries. The study systems included high natural and cultural value agroforestry systems, silvoarable systems, high value tree systems, and silvopasture systems, as well as systems where no agroforestry practices were occurring. A mixed method approach combining quantitative and qualitative approaches was taken throughout the interviews. Narrative thematic data analysis was performed. Data collection proceeded until no new themes emerged. Within a given case study, i.e. the different systems in different European regions, this sampling was performed both for
farmers who practice agroforestry and farmers who did not. Results point to a great diversity of agroforestry practices, although many of the farmers are not aware of the term or concept of agroforestry, despite implementing the practice in their own farms. While only a few farmers mentioned eligibility for direct payments in the CAP as the main reason to remove trees from their land, to avoid the reduction of the funded area, the tradition in the family or the region, learning from others, and increasing the diversification of products play the most important role in adopting or not agroforestry systems
Reduced cognitive deficits after FLASH irradiation of whole mouse brain are associated with less hippocampal dendritic spine loss and neuroinflammation
Aim
To evaluate the impact of ultra-rapid FLASH mouse whole brain irradiation on hippocampal dendritic spines and neuroinflammation, factors associated with cognitive impairment after brain irradiation.
Methods
We administered 30 Gy whole brain irradiation to C57BL6/J mice in sub-second (FLASH) vs. 240 s conventional delivery time keeping all other parameters constant, using a custom configured clinical linac. Ten weeks post-irradiation, we evaluated spatial and non-spatial object recognition using novel object location and object recognition testing. We measured dendritic spine density by tracing Golgi-stained hippocampal neurons and evaluated neuroinflammation by CD68 immunostaining, a marker of activated microglia, and expression of 10 pro-inflammatory cytokines using a multiplex immunoassay.
Results
At ten weeks post-irradiation, compared to unirradiated controls, conventional delivery time irradiation significantly impaired novel object location and recognition tasks whereas the same dose given in FLASH delivery did not. Conventional delivery time, but not FLASH, was associated with significant loss of dendritic spine density in hippocampal apical dendrites, with a similar non-significant trend in basal dendrites. Conventional delivery time was associated with significantly increased CD68-positive microglia compared to controls whereas FLASH was not. Conventional delivery time was associated with significant increases in 5 of 10 pro-inflammatory cytokines in the hippocampus (and non-significant increases in another 3), whereas FLASH was associated with smaller increases in only 3.
Conclusion
Reduced cognitive impairment and associated neurodegeneration were observed with FLASH compared to conventional delivery time irradiation, potentially through decreased induction of neuroinflammation, suggesting a promising approach to increasing therapeutic index in radiation therapy of brain tumors
Galaxy Assembly Bias on the Red Sequence
Using samples drawn from the Sloan Digital Sky Survey, we study the
relationship between local galaxy density and the properties of galaxies on the
red sequence. After removing the mean dependence of average overdensity (or
"environment") on color and luminosity, we find that there remains a strong
residual trend between luminosity-weighted mean stellar age and environment,
such that galaxies with older stellar populations favor regions of higher
overdensity relative to galaxies of like color and luminosity (and hence of
like stellar mass). Even when excluding galaxies with recent star-formation
activity (i.e., younger mean stellar ages) from the sample, we still find a
highly significant correlation between stellar age and environment at fixed
stellar mass. This residual age-density relation provides direct evidence for
an assembly bias on the red sequence such that galaxies in higher-density
regions formed earlier than galaxies of similar mass in lower-density
environments. We discuss these results in the context of the age-metallicity
degeneracy and in comparison to previous studies at low and intermediate
redshift. Finally, we consider the potential role of assembly bias in
explaining recent results regarding the evolution of post-starburst (or
post-quenching) galaxies and the environmental dependence of the type Ia
supernova rate.Comment: Accepted for publication in MNRA
Health and wellbeing of women aged 18 to 23 in 2013 and 1996: findings from the Australian Longitudinal Study on Women’s Health
Reorganization of surviving mammal communities after the end-Pleistocene megafaunal extinction
Large mammals are at high risk of extinction globally. To understand the consequences of their demise for community assembly, we tracked community structure through the end- Pleistocene megafaunal extinction in North America.We decomposed the effects of biotic and abiotic factors by analyzing co-occurrence within the mutual ranges of species pairs. Although shifting climate drove an increase in niche overlap, co-occurrence decreased, signaling shifts in biotic interactions. Furthermore, the effect of abiotic factors on cooccurrence remained constant over time while the effect of biotic factors decreased. Biotic factors apparently played a key role in continental-scale community assembly before the extinctions. Specifically, large mammals likely promoted co-occurrence in the Pleistocene, and their loss contributed to the modern assembly pattern in which co-occurrence frequently falls below random expectations.
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