Creating a New Learning Model to Avoid Skills Gaps and to Fulfil the Future Needs of the Knowledge Society

In: A.J. Kallenberg and M.J.J.M. van de Ven (Eds), 2002, The New Educational Benefits of ICT in Higher Education: Proceedings. Rotterdam: Erasmus Plus BV, OECR ISBN 90-9016127-9The situation in the education institutions and the challenges for human resources activities inside companies changed rapidly the last years. It is not (only) because of the integration and use of new technologies. It is due to a general need to change the paradigm of new learning models (and theories) in accordance with new demands in the knowledge society. Strategic blended eLearning is an opportunity for institutions, universities and companies to utilise the “power” of technology for real social and educational change bringing benefits to all its users. Online education and learning can make a huge impact on the way companies and educational institutions do business. The Web can increase their potential significantly, giving them awareness on a larger scale and increasing or even creating revenue. From a corporate point of view it is recognised that in this day and age where use of technology and business methodologies are all relatively similar organisations need something more unusual to be considered “leading edge”. Creating a corporate university or online learning environment, can educate the people who work on the frontlines of a business. If they are well informed, impart a consistent message and feel valued they become positive ambassadors for the organisation, giving them a competitive advantage, increased productivity and an enhanced knowledge capital. Therefore it is in any case useful to be aware more clearly what the effects of strategic blended eLearning and the IT-integration can offer. The speech/workshop will highlight some of these effects looking at promising examples and methods and discuss the need of the creation of a new learning model. Furthermore the speech/workshop will argue, how this change can influence the requirements to all actors inside the “old” and “new” learning model

Struggling to a monumental triumph : Re-assessing the final stages of the smallpox eradication program in India, 1960-1980

The global smallpox program is generally presented as the brainchild of a handful of actors from the WHO headquarters in Geneva and at the agency's regional offices. This article attempts to present a more complex description of the drive to eradicate smallpox. Based on the example of India, a major focus of the campaign, it is argued that historians and public health officials should recognize the varying roles played by a much wider range of participants. Highlighting the significance of both Indian and international field officials, the author shows how bureaucrats and politicians at different levels of administration and society managed to strengthen—yet sometimes weaken—important program components. Centrally dictated strategies developed at WHO offices in Geneva and New Delhi, often in association with Indian federal authorities, were reinterpreted by many actors and sometimes changed beyond recognition

French Africa

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A Study of the Accuracy of Mass-Radius Relationships for Silicate-Rich and Ice-Rich Planets up to 100 Earth Masses

A mass-radius relationship is proposed for solid planets and solid cores ranging from 1 to 100 Earth-mass planets. It relies on the assumption that solid spheres are composed of iron and silicates, around which a variable amount of water is added. The M-R law has been set up assuming that the planetary composition is similar to the averaged composition for silicates and iron obtained from the major elements ratio of 94 stars hosting exoplanets. Except on Earth for which a tremendous amount of data is available, the composition of silicate mantles and metallic cores cannot be constrained. Similarly, thermal profiles are poorly known. In this work, the effect of compositional parameters and thermal profiles on radii estimates is quantified. It will be demonstrated that uncertainties related to composition and temperature are of second order compared to the effect of the water amount. The Super-Earths family includes four classes of planets: iron-rich, silicate-rich, water-rich, or with a thick atmosphere. For a given mass, the planetary radius increases significantly from the ironrich to the atmospheric-rich planet. Even if some overlaps are likely, M-R measurements could be accurate enough to ascertain the discovery of an earth-like planet .The present work describes how the amount of water can be assessed from M-R measurements. Such an estimate depends on several assumptions including i) the accuracy of the internal structure model and ii) the accuracy of mass and radius measurements. It is shown that if the mass and the radius are perfectly known, the standard deviation on the amount of water is about 4.5 %. This value increases rapidly with the radius uncertainty but does not strongly depend on the mass uncertainty.Comment: In press in The Astrophysical Journa

Crossing the ballistic-ohmic transition via high energy electron irradiation

P.H.M. and M.D.B. received PhD studentship support from the UK Engineering and Physical Science Research Council via Grant No. EP/L015110/1. C.P. and P.J.W.M. are supported by the European Research Council under the European Union's Horizon 2020 research and innovation programme (Microstructured Topological Materials Grant No. 715730). E. Z. acknowledges support from the International Max Planck Research School for Chemistry and Physics of Quantum Materials (IMPRS-CPQM). Irradiation experiments performed on the SIRIUS platform were supported by the French National Network of Accelerators for Irradiation and Analysis of Molecules and Materials (EMIR&A) under Project No. EMIR 2019 18-7099.The delafossite metal PtCoO2 is among the highest-purity materials known, with low-temperature mean free path up to 5 μm in the best as-grown single crystals. It exhibits a strongly faceted, nearly hexagonal Fermi surface. This property has profound consequences for nonlocal transport within this material, such as in the classic ballistic-regime measurement of bend resistance in mesoscopic squares. Here, we report the results of experiments in which high-energy electron irradiation was used to introduce pointlike disorder into such squares, reducing the mean free path and therefore the strength of the ballistic-regime transport phenomena. We demonstrate that high-energy electron irradiation is a well-controlled technique to cross from nonlocal to local transport behavior and therefore determine the nature and extent of unconventional transport regimes. Using this technique, we confirm the origins of the directional ballistic effects observed in delafossite metals and demonstrate how the strongly faceted Fermi surface both leads to unconventional transport behavior and enhances the length scale over which such effects are important. © 2023 authors. Published by the American Physical Society. Published by the American Physical Society under the terms of the "https://creativecommons.org/licenses/by/4.0/"Creative Commons Attribution 4.0 International license. Further distribution of this work must maintain attribution to the author(s) and the published article's title, journal citation, and DOI. Open access publication funded by the Max Planck Society.Publisher PDFPeer reviewe

Microstructural and magnetic characterization of Ni0.5Zn0.5Fe2O4 ferrite nanoparticles

International audienc

Sex-Biased Control of Inflammation and Metabolism by a Mitochondrial Nod-Like Receptor.

Mitochondria regulate steroid hormone synthesis, and in turn sex hormones regulate mitochondrial function for maintaining cellular homeostasis and controlling inflammation. This crosstalk can explain sex differences observed in several pathologies such as in metabolic or inflammatory disorders. Nod-like receptor X1 (NLRX1) is a mitochondria-associated innate receptor that could modulate metabolic functions and attenuates inflammatory responses. Here, we showed that in an infectious model with the human protozoan parasite, Leishmania guyanensis, NLRX1 attenuated inflammation in females but not in male mice. Analysis of infected female and male bone marrow derived macrophages showed both sex- and genotype-specific differences in both inflammatory and metabolic profiles with increased type I interferon production, mitochondrial respiration, and glycolytic rate in Nlrx1-deficient female BMDMs in comparison to wild-type cells, while no differences were observed between males. Transcriptomics of female and male BMDMs revealed an altered steroid hormone signaling in Nlrx1-deficient cells, and a "masculinization" of Nlrx1-deficient female BMDMs. Thus, our findings suggest that NLRX1 prevents uncontrolled inflammation and metabolism in females and therefore may contribute to the sex differences observed in infectious and inflammatory diseases

Effects of experimental warming on carbon sink function of a temperate pristine mire : the PEATWARM project.

communication oraleInternational audienceWithin the PEATWARM project, we use Sphagnum peatlands as a model to analyse their vulnerability to climate change using an experimental system (ITEX) that simulates in situ an increase in average temperature. We aim to determine the effects of temperature increase on the vegetation, the balance of above- and belowground gas fluxes (CO2 and CH4), the microbial diversity and activity in Sphagnum mosses and in peat, and the dynamics of labile and recalcitrant organic matter of peat. The ultimate objective is the creation of a biogeochemical model of C coupled with N and S cycles that includes interactions between these key compartments

DNA Nucleobase Synthesis at Titan Atmosphere Analog by Soft X-rays

Titan, the largest satellite of Saturn, has an atmosphere chiefly made up of N2 and CH4 and includes traces of many simple organic compounds. This atmosphere also partly consists of haze and aerosol particles which during the last 4.5 gigayears have been processed by electric discharges, ions, and ionizing photons, being slowly deposited over the Titan surface. In this work, we investigate the possible effects produced by soft X-rays (and secondary electrons) on Titan aerosol analogs in an attempt to simulate some prebiotic photochemistry. The experiments have been performed inside a high vacuum chamber coupled to the soft X-ray spectroscopy beamline at the Brazilian Synchrotron Light Source, Campinas, Brazil. In-situ sample analyses were performed by a Fourier transform infrared spectrometer. The infrared spectra have presented several organic molecules, including nitriles and aromatic CN compounds. After the irradiation, the brownish-orange organic residue (tholin) was analyzed ex-situ by gas chromatographic (GC/MS) and nuclear magnetic resonance (1H NMR) techniques, revealing the presence of adenine (C5H5N5), one of the constituents of the DNA molecule. This confirms previous results which showed that the organic chemistry on the Titan surface can be very complex and extremely rich in prebiotic compounds. Molecules like these on the early Earth have found a place to allow life (as we know) to flourish.Comment: To appear in Journal of Physical Chemistry A.; Number of pages: 6; Number of Figures: 5; Number of Tables: 1; Number of references:49; Full paper at http://pubs.acs.org/doi/abs/10.1021/jp902824