279 research outputs found
Everyday micro-influencers and their impact on corporate brand reputation
Social media influencers (SMIs) are an important actor within the social media domain impacting upon organisations and brands. Traditionally SMIs are seen as individuals with millions of followers (Audrezet et al., 2018), however, there are also micro-influencers who have a relatively small follower base of less than 10,000 followers (Lin, Bruning, & Swarna, 2018). These micro-influencers are now being recognised in the practitioner domain as having higher engagement and trust factors than a professional-type of influencer/ celebrity with their millionplus follower-base (Main, 2017; Hyman, 2018). There remains a dearth of research on (EDMIs) everyday micro-influencers (unpaid, noncommercial, social media micro-influencers who share their experiences of corporate brands with their followers as a part of their daily lives). This study sought to understand the impact that EDMIs can have on a firm's corporate brand reputation through receivers being exposed to their positive and negative experiences. Secondly, we aimed to establish the specific variables that influence a receiver's evaluation of a firm's corporate brand reputation after exposure to positive and negative tweets from EDMI
Canadian Hydrogen Intensity Mapping Experiment (CHIME) Pathfinder
A pathfinder version of CHIME (the Canadian Hydrogen Intensity Mapping
Experiment) is currently being commissioned at the Dominion Radio Astrophysical
Observatory (DRAO) in Penticton, BC. The instrument is a hybrid cylindrical
interferometer designed to measure the large scale neutral hydrogen power
spectrum across the redshift range 0.8 to 2.5. The power spectrum will be used
to measure the baryon acoustic oscillation (BAO) scale across this poorly
probed redshift range where dark energy becomes a significant contributor to
the evolution of the Universe. The instrument revives the cylinder design in
radio astronomy with a wide field survey as a primary goal. Modern low-noise
amplifiers and digital processing remove the necessity for the analog
beamforming that characterized previous designs. The Pathfinder consists of two
cylinders 37\,m long by 20\,m wide oriented north-south for a total collecting
area of 1,500 square meters. The cylinders are stationary with no moving parts,
and form a transit instrument with an instantaneous field of view of
100\,degrees by 1-2\,degrees. Each CHIME Pathfinder cylinder has a
feedline with 64 dual polarization feeds placed every 30\,cm which
Nyquist sample the north-south sky over much of the frequency band. The signals
from each dual-polarization feed are independently amplified, filtered to
400-800\,MHz, and directly sampled at 800\,MSps using 8 bits. The correlator is
an FX design, where the Fourier transform channelization is performed in FPGAs,
which are interfaced to a set of GPUs that compute the correlation matrix. The
CHIME Pathfinder is a 1/10th scale prototype version of CHIME and is designed
to detect the BAO feature and constrain the distance-redshift relation.Comment: 20 pages, 12 figures. submitted to Proc. SPIE, Astronomical
Telescopes + Instrumentation (2014
Anterior Talofibular Ligament Repair With Suture Tape Augmentation
The most common injury sustained to the ankle ligaments is a result of inversion of the foot. This mechanism results in injury to the anterior talofibular ligament alone or in conjunction with the calcaneofibular ligament and posterior talofibular ligament. Patients experiencing recurrent ankle sprains despite nonoperative measures often require surgical management. Recent focus has been on augmentation procedures to improve the stability of a lateral ankle ligament repair by protecting it during the healing phase and supporting early mobilization. This article describes, with video illustration, anterior talofibular ligament repair with suture tape augmentation
Molecular profiling of signet ring cell colorectal cancer provides a strong rationale for genomic targeted and immune checkpoint inhibitor therapies
We would like to thank all patients whose samples were used in this study. We are also thankful to the Northern Ireland Biobank and Grampian Biorepository for providing us with tissue blocks and patient data; and Dr HG Coleman (Queen’s University Belfast) for her advice on statistical analyses. This work has been carried out with financial support from Cancer Research UK (grant: C11512/A18067), Experimental Cancer Medicine Centre Network (grant: C36697/A15590 from Cancer Research UK and the NI Health and Social Care Research and Development Division), the Sean Crummey Memorial Fund and the Tom Simms Memorial Fund. The Northern Ireland Biobank is funded by HSC Research and Development Division of the Public Health Agency in Northern Ireland and Cancer Research UK through the Belfast CRUK Centre and the Northern Ireland Experimental Cancer Medicine Centre; additional support was received from Friends of the Cancer Centre. The Northern Ireland Molecular Pathology Laboratory which is responsible for creating resources for the Northern Ireland Biobank has received funding from Cancer Research UK, Friends of the Cancer Centre and Sean Crummey Foundation.Peer reviewedPublisher PD
The Atacama Cosmology Telescope: A Measurement of the Thermal Sunyaev-Zel'dovich Effect Using the Skewness of the CMB Temperature Distribution
We present a detection of the unnormalized skewness induced by the
thermal Sunyaev-Zel'dovich (tSZ) effect in filtered Atacama Cosmology Telescope
(ACT) 148 GHz cosmic microwave background temperature maps. Contamination due
to infrared and radio sources is minimized by template subtraction of resolved
sources and by constructing a mask using outlying values in the 218 GHz
(tSZ-null) ACT maps. We measure = -31 +- 6 \mu K^3 (measurement error
only) or +- 14 \mu K^3 (including cosmic variance error) in the filtered ACT
data, a 5-sigma detection. We show that the skewness is a sensitive probe of
sigma_8, and use analytic calculations and tSZ simulations to obtain
cosmological constraints from this measurement. From this signal alone we infer
a value of sigma_8= 0.79 +0.03 -0.03 (68 % C.L.) +0.06 -0.06 (95 % C.L.). Our
results demonstrate that measurements of non-Gaussianity can be a useful method
for characterizing the tSZ effect and extracting the underlying cosmological
information.Comment: 9 pages, 5 figures. Replaced with version accepted by Phys. Rev. D,
with improvements to the likelihood function and the IR source treatment;
only minor changes in the result
Alcohol-related risk and harm amongst young offenders aged 11-17
The authors affiliations can be found at the end of this article. Abstract Purpose -The purpose of this paper is to examine the prevalence of alcohol use disorders (AUDs) amongst young people in the criminal justice system (CJS) in the North East of England and to compare the ability of the Alcohol Use Disorders Identification Test (AUDIT) to the Youth Justice Board ASSET tool in identifying alcohol-related need in Youth Offending Team (YOT) clients. Design/methodology/approach -A validated screening tool (AUDIT) was used to identify alcohol-related health risk or harm. Findings from AUDIT were compared with those of the standard criminogenic risk screening tool used in CJS (ASSET). An anonymous cross-sectional questionnaire was administered during a one-month period in 2008. The questionnaires were completed by 11-17-year-old offenders who were in contact with three YOTs, one Youth Offending Institution and one Secure Training Estate. Findings -In total, 429 questionnaires were completed out of a possible 639 (67 per cent). The majority (81 per cent) of the young offenders were identified as experiencing alcohol-related health risk or harm and 77 per cent scored within a possibly alcohol-dependent range. In total, 77 (30 per cent) of young people completing both assessments were identified as having an AUD by AUDIT but not identified as needing alcohol-related treatment using ASSET. Research limitations/implications -This research was confined to one geographical area of England, however, the results show that even in this area of high drinking by young people the levels of AUDs amongst young people in the CJS are very high. Social implications -There are major social implications to this research. It is imperative for changes to be made to the care pathways in place in the UK for young people coming through the CJS with alcohol-related issues. Originality/value -This paper adds to the evidence base by using well-validated tools to measure alcohol use amongst young people in the CJS in the UK
Microbial ligand costimulation drives neutrophilic steroid-refractory asthma
Funding: The authors thank the Wellcome Trust (102705) and the Universities of Aberdeen and Cape Town for funding. This research was also supported, in part, by National Institutes of Health GM53522 and GM083016 to DLW. KF and BNL are funded by the Fonds Wetenschappelijk Onderzoek, BNL is the recipient of an European Research Commission consolidator grant and participates in the European Union FP7 programs EUBIOPRED and MedALL. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer reviewedPublisher PD
The Atacama Cosmology Telescope: Data Characterization and Map Making
We present a description of the data reduction and mapmaking pipeline used
for the 2008 observing season of the Atacama Cosmology Telescope (ACT). The
data presented here at 148 GHz represent 12% of the 90 TB collected by ACT from
2007 to 2010. In 2008 we observed for 136 days, producing a total of 1423 hours
of data (11 TB for the 148 GHz band only), with a daily average of 10.5 hours
of observation. From these, 1085 hours were devoted to a 850 deg^2 stripe (11.2
hours by 9.1 deg) centered on a declination of -52.7 deg, while 175 hours were
devoted to a 280 deg^2 stripe (4.5 hours by 4.8 deg) centered at the celestial
equator. We discuss sources of statistical and systematic noise, calibration,
telescope pointing, and data selection. Out of 1260 survey hours and 1024
detectors per array, 816 hours and 593 effective detectors remain after data
selection for this frequency band, yielding a 38% survey efficiency. The total
sensitivity in 2008, determined from the noise level between 5 Hz and 20 Hz in
the time-ordered data stream (TOD), is 32 micro-Kelvin sqrt{s} in CMB units.
Atmospheric brightness fluctuations constitute the main contaminant in the data
and dominate the detector noise covariance at low frequencies in the TOD. The
maps were made by solving the least-squares problem using the Preconditioned
Conjugate Gradient method, incorporating the details of the detector and noise
correlations. Cross-correlation with WMAP sky maps, as well as analysis from
simulations, reveal that our maps are unbiased at multipoles ell > 300. This
paper accompanies the public release of the 148 GHz southern stripe maps from
2008. The techniques described here will be applied to future maps and data
releases.Comment: 20 pages, 18 figures, 6 tables, an ACT Collaboration pape
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