844 research outputs found
The importance of crown dimensions to improve tropical tree biomass estimates
Tropical forests play a vital role in the global carbon cycle, but the amount of carbon they contain and its spatial distribution remain uncertain. Recent studies suggest that once tree height is accounted for in biomass calculations, in addition to diameter and wood density, carbon stock estimates are reduced in many areas. However, it is possible that larger crown sizes might offset the reduction in biomass estimates in some forests where tree heights are lower because even comparatively short trees develop large, well-lit crowns in or above the forest canopy. While current allometric models and theory focus on diameter, wood density, and height, the inďŹuence of crown size and structure has not been well studied.To test the extent to which accounting for crown parameters can improve biomass estimates, we harvested and weighed 51 trees (11â169 cm diameter) in southwestern Amazonia where no direct biomass measurements have been made. The trees in our study had nearly half of total above ground biomass in the branches (44% Âą 2% [mean Âą SE]), demonstrating the importance of accounting for tree crowns. Consistent with our predictions, key pantropical equations that include height, but do not account for crown dimensions, underestimated the sum total biomass of all 51 trees by 11% to 14%, primarily due to substantial underestimates of many of the largest trees. In our models, including crown radius greatly improves performance and reduces error, especially for the largest trees. In addition, over the full data set, crown radius explained more variation in above ground biomass (10.5%) than height (6.0%). Crown form is also important: trees with a monopodial architectural type are estimated to have 21â44% less mass than trees with other growth patterns. Our analysis suggests that accounting for crown allometry would substantially improve the accuracy of tropical estimates of tree biomass and its distribution in primary and degraded forests
New evidence for a massive black hole at the centre of the quiescent galaxy M32
Massive black holes are thought to reside at the centres of many galaxies,
where they power quasars and active galactic nuclei. But most galaxies are
quiescent, indicating that any central massive black hole present will be
starved of fuel and therefore detectable only through its gravitational
influence on the motions of the surrounding stars. M32 is a nearby, quiescent
elliptical galaxy in which the presence of a black hole has been suspected;
however, the limited resolution of the observational data and the restricted
classes of models used to interpret this data have made it difficult to rule
out alternative explanations, such as models with an anisotropic stellar
velocity distribution and no dark mass or models with a central concentration
of dark objects (for example, stellar remnants or brown dwarfs). Here we
present high-resolution optical HST spectra of M32, which show that the stellar
velocities near the centre of this galaxy exceed those inferred from previous
ground-based observations. We use a range of general dynamical models to
determine a central dark mass concentration of (3.4 +/- 1.6) x 10^6 solar
masses, contained within a region only 0.3 pc across. This leaves a massive
black hole as the most plausible explanation of the data, thereby strengthening
the view that such black holes exist even in quiescent galaxies.Comment: 8 pages, LaTeX, 3 figures; mpeg animation of the stellar motions in
M32 available at http://oposite.stsci.edu/pubinfo/Anim.htm
Mitochondrial targeting adaptation of the hominoid-specific glutamate dehydrogenase driven by positive Darwinian selection
Many new gene copies emerged by gene duplication in hominoids, but little is known with respect to their functional evolution. Glutamate dehydrogenase (GLUD) is an enzyme central to the glutamate and energy metabolism of the cell. In addition to the single, GLUD-encoding gene present in all mammals (GLUD1), humans and apes acquired a second GLUD gene (GLUD2) through retroduplication of GLUD1, which codes for an enzyme with unique, potentially brain-adapted properties. Here we show that whereas the GLUD1 parental protein localizes to mitochondria and the cytoplasm, GLUD2 is specifically targeted to mitochondria. Using evolutionary analysis and resurrected ancestral protein variants, we demonstrate that the enhanced mitochondrial targeting specificity of GLUD2 is due to a single positively selected glutamic acid-to-lysine substitution, which was fixed in the N-terminal mitochondrial targeting sequence (MTS) of GLUD2 soon after the duplication event in the hominoid ancestor ~18â25 million years ago. This MTS substitution arose in parallel with two crucial adaptive amino acid changes in the enzyme and likely contributed to the functional adaptation of GLUD2 to the glutamate metabolism of the hominoid brain and other tissues. We suggest that rapid, selectively driven subcellular adaptation, as exemplified by GLUD2, represents a common route underlying the emergence of new gene functions
CMIP5 climate model analyses: Climate extremes in the United States
Given the increases in spatial resolution and other improvements in climate modeling capabilities over the last decade since the CMIP3 simulations were completed, CMIP5 provides a unique opportunity to assess scientific understanding of climate variability and change over a range of historical and future conditions. With participation from over 20 modeling groups and more than 40 global models, CMIP5 represents the latest and most ambitious coordinated international climate model intercomparison exercise to date. Observations dating back to 1900 show that the temperatures in the twenty-first century have the largest spatial extent of record breaking and much above normal mean monthly maximum and minimum temperatures. The 20-yr return value of the annual maximum or minimum daily temperature is one measure of changes in rare temperature extremes
The moment of truth for WIMP Dark Matter
We know that dark matter constitutes 85% of all the matter in the Universe,
but we do not know of what it is made. Amongst the many Dark Matter candidates
proposed, WIMPs (weakly interacting massive particles) occupy a special place,
as they arise naturally from well motivated extensions of the standard model of
particle physics. With the advent of the Large Hadron Collider at CERN, and a
new generation of astroparticle experiments, the moment of truth has come for
WIMPs: either we will discover them in the next five to ten years, or we will
witness the inevitable decline of WIMP paradigm.Comment: To appear in Nature (Nov 18, 2010
Dark Matter from Minimal Flavor Violation
We consider theories of flavored dark matter, in which the dark matter
particle is part of a multiplet transforming nontrivially under the flavor
group of the Standard Model in a manner consistent with the principle of
Minimal Flavor Violation (MFV). MFV automatically leads to the stability of the
lightest state for a large number of flavor multiplets. If neutral, this
particle is an excellent dark matter candidate. Furthermore, MFV implies
specific patterns of mass splittings among the flavors of dark matter and
governs the structure of the couplings between dark matter and ordinary
particles, leading to a rich and predictive cosmology and phenomenology. We
present an illustrative phenomenological study of an effective theory of a
flavor SU(3)_Q triplet, gauge singlet scalar.Comment: 10 pages, 2 figures; v2: references added, minor changes to collider
analysis, conclusions unchange
Community-based intervention to promote breast cancer awareness and screening: The Korean experience
<p>Abstract</p> <p>Background</p> <p>There are many differences in culture, community identity, community participation, and ownership between communities in Western and Asian countries; thus, it is difficult to adopt the results of community intervention studies from Western countries. In this study, we conducted a multicity, multicomponent community intervention trial to correct breast cancer myths and promote screening mammography for women living in an urban community in Korea.</p> <p>Methods</p> <p>A 6-month, 2-city community intervention trial was conducted. In the intervention city, 480 women were surveyed at baseline and 7 months later to evaluate the effects of the intervention program. Strategies implemented in the intervention city included community outreach and clinic and pharmacy-based in-reach strategies.</p> <p>Results</p> <p>This study showed a 20.4-percentage-point decrease in myths about the link between cancer and breast size, a 19.2-percentage-point decrease in myths concerning mammography costs, and a 14.1-percentage-point increase in intention to undergo screening mammography. We also saw a 23.4-percentage-point increase in the proportion of women at the action stage of the transtheoretical model in the intervention city. In the comparison city, smaller decreases and increases were observed.</p> <p>Conclusions</p> <p>Our study showed the value of an intervention study aimed at reducing belief in breast cancer myths in an urban community in Korea. The invention also made women more likely to undergo mammography in future.</p
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Risk measures for direct real estate investments with non-normal or unknown return distributions
The volatility of returns is probably the most widely used risk measure for real estate. This is rather surprising since a number of studies have cast doubts on the view that volatility can capture the manifold risks attached to properties and corresponds to the risk attitude of investors. A central issue in this discussion is the statistical properties of real estate returnsâin contrast to neoclassical capital market theory they are mostly non-normal and often unknown, which render many statistical measures useless. Based on a literature review and an analysis of data from Germany we provide evidence that volatility alone is inappropriate for measuring the risk of direct real estate.
We use a unique data sample by IPD, which includes the total returns of 939 properties across different usage types (56% office, 20% retail, 8% others and 16% residential properties) from 1996 to 2009, the German IPD Index, and the German Property Index. The analysis of the distributional characteristics shows that German real estate returns in this period were not normally distributed and that a logistic distribution would have been a better fit. This is in line with most of the current literature on this subject and leads to the question which indicators are more appropriate to measure real estate risks. We suggest that a combination of quantitative and qualitative risk measures more adequately captures real estate risks and conforms better with investor attitudes to risk. Furthermore, we present criteria for the purpose of risk classification
Socio-Economic Instability and the Scaling of Energy Use with Population Size
The size of the human population is relevant to the development of a sustainable world, yet the forces setting growth or declines in the human population are poorly understood. Generally, population growth rates depend on whether new individuals compete for the same energy (leading to Malthusian or density-dependent growth) or help to generate new energy (leading to exponential and super-exponential growth). It has been hypothesized that exponential and super-exponential growth in humans has resulted from carrying capacity, which is in part determined by energy availability, keeping pace with or exceeding the rate of population growth. We evaluated the relationship between energy use and population size for countries with long records of both and the world as a whole to assess whether energy yields are consistent with the idea of an increasing carrying capacity. We find that on average energy use has indeed kept pace with population size over long time periods. We also show, however, that the energy-population scaling exponent plummets during, and its temporal variability increases preceding, periods of social, political, technological, and environmental change. We suggest that efforts to increase the reliability of future energy yields may be essential for stabilizing both population growth and the global socio-economic system
Histone deacetylase inhibitor, butyrate, attenuates lipopolysaccharide-induced acute lung injury in mice
<p>Abstract</p> <p>Background</p> <p>Histone deacetylase (HDAC) inhibitors, developed as promising anti-tumor drugs, exhibit their anti-inflammatory properties due to their effects on reduction of inflammatory cytokines.</p> <p>Objective</p> <p>To investigate the protective effect of butyrate, a HDAC inhibitor, on lipopolysaccharide (LPS)-induced acute lung injury (ALI) in mice.</p> <p>Methods</p> <p>ALI was induced in Balb/c mice by intratracheally instillation of LPS (1 mg/kg). Before 1 hour of LPS administration, the mice received butyrate (10 mg/kg) orally. The animals in each group were sacrificed at different time point after LPS administration. Pulmonary histological changes were evaluated by hematoxylin-eosin stain and lung wet/dry weight ratios were observed. Concentrations of interleukin (IL)-1β and tumor necrosis factor (TNF)-ι in bronchoalveolar lavage fluid (BALF) and concentrations of nitric oxide (NO) and myeloperoxidase (MPO) activity in lung tissue homogenates were measured by enzyme-linked immunosorbent assay (ELISA). Expression of nuclear factor (NF)-κB p65 in cytoplasm and nucleus was determined by Western blot analysis respectively.</p> <p>Results</p> <p>Pretreatment with butyrate led to significant attenuation of LPS induced evident lung histopathological changes, alveolar hemorrhage, and neutrophils infiltration with evidence of reduced MPO activity. The lung wet/dry weight ratios, as an index of lung edema, were reduced by butyrate administration. Butyrate also repressed the production of TNF-ι, IL-1β and NO. Furthermore, the expression of NF-κB p65 in nucleus was markedly suppressed by butyrate pretreatment.</p> <p>Conclusions</p> <p>Butyrate had a protective effect on LPS-induced ALI, which may be related to its effect on suppression of inflammatory cytokines production and NF-κB activation.</p
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