Validación de la escala de ansiedad hacia las matemáticas (EAnM) y determinación de la relación entre ansiedad hacia las matemáticas, rendimiento académico y variables demográficas en escolares Españoles

75 p.La presente investigación pretende validar la Escala de Ansiedad Hacia las Matemáticas –EAnM- creada por Arias & Palacios (2015), en una muestra de 588 estudiantes de educación secundaria y bachillerato procedentes de diversas ciudades de España, cuyas edades fluctuaron entre 12 a 19 años de edad. Con el fin de determinar la validez de constructo, es que se realizó un análisis factorial exploratorio (AFE), con el método de extracción mínimos cuadrados no ponderados y una rotación promax en la muestra final de participantes (n=410). Los resultados arrojados en el AFE dieron cuenta de un solo factor preponderante, lo cual es coherente con lo expuesto por Arias & Palacios (2015) en su investigación. Sin embargo la escala EAnM, que originalmente era de 20 ítems, quedó finalmente conformada por 17 ítems debido a los criterios de eliminación. Además para determinar la fiabilidad de la se observó el índice Omega de McDonald -.95- y el índice de Alfa de Cronbach -.94-. A su vez se investigó la validez de criterio, en la que se utilizó el rendimiento académico para la relación, y cuyos resultados arrojaron que la ansiedad se relacionó de forma negativa y moderada con el rendimiento en matemáticas (r=.44). Así mismo, se analizaron diferencias por edad y género, resultando que los escolares de entre 12 a 15 años muestran niveles ligeramente más elevados de ansiedad hacia las matemáticas que los estudiantes de mayor edad, así como las mujeres muestran niveles de ansiedad matemática más altos que los hombres.Palabras Claves: Ansiedad, Ansiedad hacia las Matemáticas, Análisis Factorial Exploratorio (AFE), Rendimiento Académico, Validació

Short-term effect of eucalyptus leachates on green food webs in headwaters

Despite the reported allelopathic nature of the Eucalyptus genus, eucalypt leachates have unknown effects on the trophic base of stream green food webs. Eucalypt plantations have increased worldwide, including riparian ecosystems. We aimed to test whether short-term eucalypt leachates might alter water chemistry, periphytic algal biomass and diatoms, and herbivorous invertebrates’ (i.e., scrapers). We studied two oligotrophic and well-preserved headwaters from NW Spain. The experiment followed a before-after control-impact paired (BACIp) design, with weekly sampling before and after eucalypt leaves addition to streams. In the stream with lower discharge, the eucalypt treatments seemed to affect increases in biomass accrual (Chl-a) and diatom assemblages, disfavouring sensitive species (e.g., Eunotia minor and Achnanthidium pyrenaicum). Therefore, the ecological status was reduced from high to good. In the stream with higher discharge, invertebrate assemblages changed with scrapers having their abundances modified in comparison with the control (e.g., Habrophlebia sp. and Elmidae). Results suggest that eucalypt leaves leachates exert toxic effects on periphyton and on diatom and invertebrate assemblages, and this effect might be mediated by discharge. Alterations at the base of stream food webs may compromise their good ecological status. Further studies are necessary to identify whether this toxicity is due to allelopathic processes

La estructura y los procesos organizacionales como dimensiones relevantes para la gestión de los centros de atención primaria de la salud (CAPS)

La Atención Primaria de Salud (APS) es reconocida como uno de los componentes claves de un Sistema de Salud efectivo. Los Centros de Atención Primaria de la Salud (CAPS) desarrollan las funciones de la APS en el sistema público de salud argentino. Si bien existe estadística pública sobre el resultado del trabajo de los CAPS, no existe conocimiento sobre la forma de organizar el trabajo para lograr sus resultados. Por lo tanto, el objetivo del proyecto se centra en analizar la organización del trabajo de los CAPS a fin de identificar dimensiones relevantes para la gestión en el cumplimiento de las funciones de la APS.Facultad de Ciencias Económica

Androgen receptor polyQ alleles and COVID-19 severity in men: a replication study

Background: Ample evidence indicates a sex-related difference in severity of COVID19, with less favorable outcomes observed in men. Genetic factors have been proposed as candidates to explain this difference. The polyglutamine (polyQ) polymorphism in the androgen receptor gene has been recently described as a genetic biomarker of COVID-19 severity. Objective: To test the association between the androgen receptor polyQ polymorphism and COVID-19 severity in a large cohort of COVID-19 male patients. Materials and methods: This study included 1136 male patients infected with SARSCoV-2 as confirmed by positive PCR. Patients were retrospectively and prospectively enrolled from March to November 2020. Patients were classified according to their severity into three categories: oligosymptomatic, hospitalized and severe patients requiring ventilatory support. The number of CAG repeats (polyQ polymorphism) at the androgen receptor was obtained by PCR and patients were classified as either short (<23 repeats) or long (≥23 repeats) allele carriers. The association between polyQ alleles (short or long) and COVID-19 severity was assessed by Chi-squared (Chi2) and logistic regression analysis. Results: The mean number of polyQ CAG repeats was 22 (±3). Patients were classified as oligosymptomatic (15.5%), hospitalized (63.2%), and severe patients (21.3%) requiring substantial respiratory support. PolyQ alleles distribution did not show significant differences between severity classes in our cohort (Chi2 test p > 0.05). Similar results were observed after adjusting by known risk factors such as age, comorbidities, and ethnicity (multivariate logistic regression analysis)Instituto de Salud Carlos III (ISCIII), Spanish Ministry of Science and Innovation (COVID-19 Research Call; COV20/00181) co-financed by European Development Regional Fund (FEDER, A way to achieve Europe); Estrella de Levante (E G-N); Colabora Mujer (E G-N); Instituto de Salud Carlos III (Centro de Investigación en Red de Enfermedades Raras, CIBERer); IIS-Fundación Jiménez Díaz-UAM Chair in Genomic Medicine; Instituto de Salud Carlos III (ISCIII), Spanish Ministry of Science and Innovation (Miguel Servet Contract Number: CP17/00006 and Juan Rodes Contract Number: JR17/00020) co-financied by European Regional Development Fund (FEDER); CEGEN-PRB3-ISCIII is funded by ISCIII and ERDF, Grant Number: PT17/001

Red AUTI : Red de Aplicaciones y Usabilidad de la Televisión digital Interactiva

Desde el año 2012 diversas universidades iberoamericanas conforman la Red de Aplicaciones y Usabilidad de la Televisión Digital Interactiva (RedAUTI) de la CYTED coordinada por la UNLP. La línea de investigación y desarrollo presentada consiste en estudiar, desarrollar y evaluar aplicaciones de Televisión Digital Interactiva (TVDi). Uno de los principales objetivos es la formación de recursos humanos y fortalecimiento de la investigación mediante el trabajo intergrupal entre diferentes instituciones nacionales y extranjeras.Eje: Tecnología Informática Aplicada en EducaciónRed de Universidades con Carreras en Informática (RedUNCI

Red AUTI : Red de Aplicaciones y Usabilidad de la Televisión digital Interactiva

Desde el año 2012 diversas universidades iberoamericanas conforman la Red de Aplicaciones y Usabilidad de la Televisión Digital Interactiva (RedAUTI) de la CYTED coordinada por la UNLP. La línea de investigación y desarrollo presentada consiste en estudiar, desarrollar y evaluar aplicaciones de Televisión Digital Interactiva (TVDi). Uno de los principales objetivos es la formación de recursos humanos y fortalecimiento de la investigación mediante el trabajo intergrupal entre diferentes instituciones nacionales y extranjeras.Eje: Tecnología Informática Aplicada en EducaciónRed de Universidades con Carreras en Informática (RedUNCI

Red AUTI : Red de Aplicaciones y Usabilidad de la Televisión digital Interactiva

Desde el año 2012 diversas universidades iberoamericanas conforman la Red de Aplicaciones y Usabilidad de la Televisión Digital Interactiva (RedAUTI) de la CYTED coordinada por la UNLP. La línea de investigación y desarrollo presentada consiste en estudiar, desarrollar y evaluar aplicaciones de Televisión Digital Interactiva (TVDi). Uno de los principales objetivos es la formación de recursos humanos y fortalecimiento de la investigación mediante el trabajo intergrupal entre diferentes instituciones nacionales y extranjeras.Eje: Tecnología Informática Aplicada en EducaciónRed de Universidades con Carreras en Informática (RedUNCI

Vaspin in atherosclerotic disease and cardiovascular risk in axial spondyloarthritis: a genetic and serological study

Background: Vaspin is a novel anti-inflammatory adipokine associated with cardiovascular (CV) disease and inflammation in chronic inflammatory conditions different from axial spondyloarthritis (axSpA). Given the high incidence of CV disease (mainly due to accelerated atherosclerosis) exhibited by axSpA patients, we wondered if vaspin could also be a key molecule in this process. However, data on the role of vaspin regarding atherosclerotic disease in the context of axSpA is scarce. For this reason, we aimed to evaluate the implication of vaspin, at the genetic and serological level, in subclinical atherosclerosis and CV risk in axSpA. Methods: This study included 510 patients diagnosed with axSpA. Carotid ultrasound (US) was performed to evaluate the presence of subclinical atherosclerosis. Three vaspin gene variants (rs2236242, rs7159023, and rs35262691) were genotyped by TaqMan probes. Serum vaspin levels were assessed by enzyme-linked immunosorbent assay. Statistical analysis was performed using STATA® v.11.1. Results: Serum vaspin levels were significantly higher in female patients than in males and also in obese patients when compared to those with normal weight (p < 0.05). At the genetic level, we disclosed that the minor allele of rs2236242 (A) was associated with lower serum vaspin levels in axSpA, while the rs7159023 minor allele (A) was linked to higher serum levels (p < 0.05). When the three polymorphisms assessed were combined conforming haplotypes, we disclosed that the TGC haplotype related to high serum levels of vaspin (p = 0.01). However, no statistically significant association was observed between vaspin and markers of subclinical atherosclerosis, both at the genetic and serological level. Conclusions: Our results revealed that vaspin is linked to CV risk factors that may influence on the atherosclerotic process in axSpA. Additionally, we disclosed that serum vaspin concentration is genetically modulated in a large cohort of patients with axSpA.This work was partially supported by funds of a NEXT-VAL grant (NVAL17/10) (Instituto de Investigación Sanitaria IDIVAL) awarded to FG. RL-M is a recipient of a Miguel Servet type I programme fellowship (grant CP16/00033) from the “Instituto de Salud Carlos III” (ISCIII) and co-funded by the European Social Fund, ESF). SR-M is supported by funds of the RETICS Program (RD16/0012/0009) from ISCIII and co-funded by the European Regional Development Fund. VP-C is supported by a pre-doctoral grant from IDIVAL (PREVAL18/01). LL-G is supported by funds of a Miguel Servet type I programme fellowship from ISCIII (grant CP16/00033, co-funded by the ESF). OG is beneficiary of a grant funded by Xunta de Galicia, Consellería de Educación, Universidade e Formación Profesional and Consellería de Economía, Emprego e Industria (GAIN), GPC IN607B2019/10

Predictors of Global Non-Motor Symptoms Burden Progression in Parkinson’s Disease. Results from the COPPADIS Cohort at 2-Year Follow-Up

Background and Objective: Non-motor symptoms (NMS) progress in different ways between Parkinson's disease (PD) patients. The aim of the present study was to (1) analyze the change in global NMS burden in a PD cohort after a 2-year follow-up, (2) to compare the changes with a control group, and (3) to identify predictors of global NMS burden progression in the PD group. Material and Methods: PD patients and controls, recruited from 35 centers of Spain from the COPPADIS cohort from January 2016 to November 2017, were followed-up with after 2 years. The Non-Motor Symptoms Scale (NMSS) was administered at baseline (V0) and at 24 months ± 1 month (V2). Linear regression models were used for determining predictive factors of global NMS burden progression (NMSS total score change from V0 to V2 as dependent variable). Results: After the 2-year follow-up, the mean NMS burden (NMSS total score) significantly increased in PD patients by 18.8% (from 45.08 ± 37.62 to 53.55 ± 42.28; p < 0.0001; N = 501; 60.2% males, mean age 62.59 ± 8.91) compared to no change observed in controls (from 14.74 ± 18.72 to 14.65 ± 21.82; p = 0.428; N = 122; 49.5% males, mean age 60.99 ± 8.32) (p < 0.0001). NMSS total score at baseline (β = -0.52), change from V0 to V2 in PDSS (Parkinson's Disease Sleep Scale) (β = -0.34), and change from V0 to V2 in NPI (Neuropsychiatric Inventory) (β = 0.25) provided the highest contributions to the model (adjusted R-squared 0.41; Durbin-Watson test = 1.865). Conclusions: Global NMS burden demonstrates short-term progression in PD patients but not in controls and identifies worsening sleep problems and neuropsychiatric symptoms as significant independent predictors of this NMS progression