The ongoing volcanic eruption of El Hierro, Canary Islands

El Hierro, the youngest of the Canary Islands (Spain), is no stranger to hazards associated with volcanic activity or to efforts to minimize the effects of these hazards on local communities. As early as 1793, administrative records of El Hierro indicate that a swarm of earthquakes was felt by locals; fearing a greater volcanic catastrophe, the first evacuation plan of an entire island in the history of the Canaries was prepared. The 1793 eruption was probably submarine with no appreciable consequences other than that the earthquakes were felt [Carracedo, 2008]; over the next roughly 215 years the island was seismically quiet. Yet seismic and volcanic activity are expected on this youngest Canary Island due to its being directly above the presumed location of the Canary Island hot spot, a mantle plume that feeds upwelling magma just under the surface, similar to the Hawaiian Islands. Because of this known geologic activity, the Spanish Instituto Geogrfco Nacional (IGN) has managed geophysical monitoring of the island since the beginning of the 1990s.Peer Reviewe

CHK1 expression in gastric cancer is modulated by p53 and RB1/E2F1: Implications in chemo/radiotherapy response

Radiation has a limited but relevant role in the adjuvant therapy of gastric cancer (GC) patients. Since Chk1 plays a critical function in cellular response to genotoxic agents, we aimed to analyze the role of Chk1 in GC as a biomarker for radiotherapy resistance. We analyzed Chk1 expression in AGS and MKN45 human GC cell lines by RT-QPCR and WB and in a small cohort of human patient’s samples. We demonstrated that Chk1 overexpression specifically increases resistance to radiation in GC cells. Accordingly, abrogation of Chk1 activity with UCN-01 and its expression with shChk1 increased sensitivity to bleomycin and radiation. Furthermore, when we assessed Chk1 expression in human samples, we found a correlation between nuclear Chk1 accumulation and a decrease in progression free survival. Moreover, using a luciferase assay we found that Chk1’s expression is controlled by p53 and RB/E2F1 at the transcriptional level. Additionally, we present preliminary data suggesting a posttranscriptional regulation mechanism, involving miR-195 and miR-503, which are inversely correlated with expression of Chk1 in radioresistant cells. In conclusion, Chk1/microRNA axis is involved in resistance to radiation in GC, and suggests Chk1 as a potential tool for optimal stratification of patients susceptible to receive adjuvant radiotherapy after surgeryThis work was supported by Instituto de Salud Carlos III–Fondo de Investigación Sanitaria (PS09/1988 to ISP; PI11-00949, pI014-1495 and Feder Funds to RP); Comunidad Autónoma de Madrid-Universidad Autónoma de Madrid (CCG10-UAM/BIO-5871 to ISP); Fundación Leticia Castillejo Castillo and Ministerio de Ciencia e Innovación (SAF2012-30862 to RSP), Spain

Tribological behavior of oils additised with a phosphonium-derived ionic liquid compared to a commercial oil

Purpose: The purpose of this paper is to study the antifriction, antiwear and tribolayer formation properties of the trihexyltetradecylphosphonium bis(2,4,4-trimethylpentyl) phosphinate ionic liquid (IL) as additive at 1 wt.% in two base oils and their mixtures, comparing the results with those of a commercial oil. Design/methodology/approach: The mixture of the base oils used in the formulation of the commercial oil SAE 0W20 plus the IL was tested under rolling/sliding and reciprocating conditions to determine the so-called Stribeck curve, the tribolayer formation and the antifriction and antiwear behaviors. Findings: The use of this IL as additive in these oils does not change their viscosity; improves the antifriction and antiwear properties of the base oils, making equal or outperforming these properties of the SAE 0W20; and the thickness and formation rate of the tribolayer resulting from the IL-surface interaction is highly dependent on the type of base oil and influence on the friction and wear results. Originality/value: The use of this IL allows to replace partial or totally commercial antifriction and antiwear additives. Peer review: The peer review history for this article is available at: https://publons.com/publon/10.1108/ILT-05-2020-0179/

The 2011 submarine volcanic eruption in El Hierro (Canary Islands)

Forty years after the Teneguía Volcano (La Palma, 1971), a submarine eruption took place off the town of La Restinga, south of El Hierro, the smallest and youngest island of the Canarian Archipelago. Precursors allowed an early detection of the event and its approximate location, suggesting it was submarine. Uncertainties derived from insufficient scientific information available to the authorities during the eruption, leading to disproportionate civil protection measures, which had an impact on the island's economy-based primarily on tourism-while residents experienced extra fear and distress. © 2012 Blackwell Publishing Ltd, The Geologists' Association & The Geological Society of London.Peer Reviewe

Modeling the Accretion Disk around the High-mass Protostar GGD 27-MM1

Recent high angular resolution (≃40 mas) ALMA observations at 1.14 mm resolve a compact (R ≃ 200 au), flattened dust structure perpendicular to the HH 80─81 jet emanating from the GGD 27-MM1 high-mass protostar, making it a robust candidate for a true accretion disk. The jet─disk system (HH 80─81/GGD 27-MM1) resembles those found in association with low- and intermediate-mass protostars. We present radiative transfer models that fit the 1.14 mm ALMA dust image of this disk, which allow us to obtain its physical parameters and predict its density and temperature structure. Our results indicate that this accretion disk is compact (R disk ≃ 170 au) and massive (≃5 M ☉), at about 20% of the stellar mass of ≃20 M ☉. We estimate the total dynamical mass of the star─disk system from the molecular line emission, finding a range between 21 and 30 M ☉, which is consistent with our model. We fit the density and temperature structures found by our model with power-law functions. These results suggest that accretion disks around massive stars are more massive and hotter than their low-mass siblings, but they still are quite stable. We also compare the temperature distribution in the GGD 27─MM1 disk with that found in low- and intermediate-mass stars and discuss possible implications for the water snow line. We have also carried out a study of the distance based on Gaia DR2 data and the population of young stellar objects in this region and from the extinction maps. We conclude that the source distance is within 1.2 and 1.4 kpc, closer than what was derived in previous studies (1.7 kpc).Fil: Añez López, N.. Instituto de Ciencias del Espacio; EspañaFil: Osorio, M.. Instituto de Astrofísica de Andalucía; EspañaFil: Busquet, G.. Instituto de Ciencias del Espacio; EspañaFil: Girart, J. M.. Instituto de Ciencias del Espacio; EspañaFil: Macías, E.. European Southern Observatory; ChileFil: Carrasco González, C.. Instituto de Radioastronomía y Astrofísica; MéxicoFil: Curiel, S.. Universidad Nacional Autonoma de Mexico. Instituto de Astronomia; MéxicoFil: Estalella, R.. Universidad de Barcelona. Facultad de Física; EspañaFil: Fernandez Lopez, Manuel. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Argentino de Radioastronomía. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Argentino de Radioastronomía; ArgentinaFil: Galván Madrid, R.. Instituto de Radioastronomía y Astrofísica; MéxicoFil: Kwon, J.. University of tokyo; JapónFil: Torrelles, J. M.. Institut de Ciencies de l’Espai; Españ

Unveiling a cluster of protostellar disks around the massive protostar GGD 27 MM1

Context. Most stars form in clusters and thus it is important to characterize the protostellar disk population in dense environments to assess whether the environment plays a role in the subsequent evolution. Specifically, it is critical to evaluate whether planet formation is altered with respect to more isolated stars formed in dark clouds. Aims. We seek to investigate the properties of the protostellar disks in the GGD 27 cluster and compare these with those obtained from disks formed in nearby regions. Methods. We used ALMA to observe the star-forming region GGD 27 at 1.14 mm with an unprecedented angular resolution, 40 mas (∼56 au), and sensitivity (∼0.002 M·). Results. We detected a cluster of 25 continuum sources, most of which likely trace disks around Class 0/I protostars. Excluding the two most massive objects, disks masses are in the range 0.003-0.05 M·. The analysis of the cluster properties indicates that GGD 27 displays moderate subclustering. This result, combined with the dynamical timescale of the radio jet (∼104 years), suggests the youthfulness of the cluster. The lack of disk mass segregation signatures may support this as well. We found a clear paucity of disks with Rdisk > 100 au. The median value of the radius is 34 au; this value is smaller than the median of 92 au for Taurus but comparable to the value found in Ophiuchus and in the Orion Nebula Cluster. In GGD 27 there is no evidence of a distance-dependent disk mass distribution (i.e., disk mass depletion due to external photoevaporation), most likely due to the cluster youth. There is a clear deficit of disks for distances 0.04 pc. This suggests that dynamical interactions far from the cluster center are weaker, although the small disks found could be the result of disk truncation. This work demonstrates the potential to characterize disks from low-mass young stellar objects in distant and massive (still deeply embedded) clustered environments.Fil: Busquet, G.. Instituto de Estudios Espaciales de Cataluña; España. Instituto de Ciencias del Espacio (ice); EspañaFil: Girart, J. M.. Instituto de Estudios Espaciales de Cataluña; España. Instituto de Ciencias del Espacio (ice); EspañaFil: Estalella, R.. Universidad de Barcelona; EspañaFil: Fernandez Lopez, Manuel. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Argentino de Radioastronomía. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Argentino de Radioastronomía; ArgentinaFil: Galván Madrid, R.. Universidad Nacional Autónoma de México; MéxicoFil: Anglada, G.. Instituto de Astrofísica de Andalucía; EspañaFil: Carrasco González, C.. Universidad Nacional Autónoma de México; MéxicoFil: Añez López, N.. Instituto de Ciencias del Espacio (ice); EspañaFil: Curiel, S.. Universidad Nacional Autónoma de México; MéxicoFil: Osorio, M.. Instituto de Astrofísica de Andalucía; EspañaFil: Rodríguez, L. F.. Universidad Nacional Autónoma de México; MéxicoFil: Torrelles, J. M.. Instituto de Estudios Espaciales de Cataluña; España. Instituto de Ciencias del Espacio (ice); Españ

Stellar populations of galaxies in the ALHAMBRA survey up to z∼1z \sim 1. I. MUFFIT: A Multi-Filter Fitting code for stellar population diagnostics

We present MUFFIT, a new generic code optimized to retrieve the main stellar population parameters of galaxies in photometric multi-filter surveys, and we check its reliability and feasibility with real galaxy data from the ALHAMBRA survey. Making use of an error-weighted $\chi^2$-test, we compare the multi-filter fluxes of galaxies with the synthetic photometry of mixtures of two single stellar populations at different redshifts and extinctions, to provide through a Monte Carlo method the most likely range of stellar population parameters (mainly ages and metallicities), extinctions, redshifts, and stellar masses. To improve the diagnostic reliability, MUFFIT identifies and removes from the analysis those bands that are significantly affected by emission lines. We highlight that the retrieved age-metallicity locus for a sample of $z \le 0.22$ early-type galaxies in ALHAMBRA at different stellar mass bins are in very good agreement with the ones from SDSS spectroscopic diagnostics. Moreover, a one-to-one comparison between the redshifts, ages, metallicities, and stellar masses derived spectroscopically for SDSS and by MUFFIT for ALHAMBRA reveals good qualitative agreements in all the parameters. In addition, and using as input the results from photometric-redshift codes, MUFFIT improves the photometric-redshift accuracy by $\sim 10$-$20\%$, and it also detects nebular emissions in galaxies, providing physical information about their strengths. Our results show the potential of multi-filter galaxy data to conduct reliable stellar population studies with the appropiate analysis techniques, as MUFFIT.Comment: 31 pages, 18 figures, accepted for publication in A&

The ALHAMBRA Survey: Bayesian Photometric Redshifts with 23 bands for 3 squared degrees

The ALHAMBRA (Advance Large Homogeneous Area Medium Band Redshift Astronomical) survey has observed 8 different regions of the sky, including sections of the COSMOS, DEEP2, ELAIS, GOODS-N, SDSS and Groth fields using a new photometric system with 20 contiguous ~ $300\AA$ filters covering the optical range, combining them with deep $JHKs$ imaging. The observations, carried out with the Calar Alto 3.5m telescope using the wide field (0.25 sq. deg FOV) optical camera LAICA and the NIR instrument Omega-2000, correspond to ~700hrs on-target science images. The photometric system was designed to maximize the effective depth of the survey in terms of accurate spectral-type and photo-zs estimation along with the capability of identification of relatively faint emission lines. Here we present multicolor photometry and photo-zs for ~438k galaxies, detected in synthetic F814W images, complete down to I~24.5 AB, taking into account realistic noise estimates, and correcting by PSF and aperture effects with the ColorPro software. The photometric ZP have been calibrated using stellar transformation equations and refined internally, using a new technique based on the highly robust photometric redshifts measured for emission line galaxies. We calculate photometric redshifts with the BPZ2 code, which includes new empirically calibrated templates and priors. Our photo-zs have a precision of $dz/(1+z_s)=1$ for I<22.5 and 1.4% for 22.5<I<24.5. Precisions of less than 0.5% are reached for the brighter spectroscopic sample, showing the potential of medium-band photometric surveys. The global $P(z)$ shows a mean redshift =0.56 for I=0.86 for I<24.5 AB. The data presented here covers an effective area of 2.79 sq. deg, split into 14 strips of 58.5'x15.5' and represents ~32 hrs of on-target.Comment: The catalog data and a full resolution version of this paper is available at https://cloud.iaa.csic.es/alhambra

Plasma coenzyme Q10 status is impaired in selected genetic conditions.

Identifying diseases displaying chronic low plasma Coenzyme Q10 (CoQ) values may be important to prevent possible cardiovascular dysfunction. The aim of this study was to retrospectively evaluate plasma CoQ concentrations in a large cohort of pediatric and young adult patients. We evaluated plasma CoQ values in 597 individuals (age range 1 month to 43 years, average 11 years), studied during the period 2005-2016. Patients were classified into 6 different groups: control group of healthy participants, phenylketonuric patients (PKU), patients with mucopolysaccharidoses (MPS), patients with other inborn errors of metabolism (IEM), patients with neurogenetic diseases, and individuals with neurological diseases with no genetic diagnosis. Plasma total CoQ was measured by reverse-phase high-performance liquid chromatography with electrochemical detection and ultraviolet detection at 275 nm. ANOVA with Bonferroni correction showed that plasma CoQ values were significantly lower in the PKU and MPS groups than in controls and neurological patients. The IEM group showed intermediate values that were not significantly different from those of the controls. In PKU patients, the Chi-Square test showed a significant association between having low plasma CoQ values and being classic PKU patients. The percentage of neurogenetic and other neurological patients with low CoQ values was low (below 8%). In conclusión, plasma CoQ monitoring in selected groups of patients with different IEM (especially in PKU and MPS patients, but also in IEM under protein-restricted diets) seems advisable to prevent the possibility of a chronic blood CoQ suboptimal status in such groups of patients